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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
effect feedback fuel jet normal pleased received report supply
We are pleased to report that we have received feedback from the jet fuel consortium to the effect that supply will be back to normal by this weekend. Solomon Makgale
effect energy higher prices
We are going to see the effect of higher energy prices trickle up to the middle-income consumers. Ken Perkins
effect good wonder
My actions and the things I say and do, I wonder if they have an effect on my daughter and the way she's going to be as a person. I just want her to be a good person. Leah Remini
effects great talk year
When you talk about effects of (winning that game), in any one year it doesn't have that great of an effect, John Lilly
effective-listening listening
Listening is a positive act: you have to put yourself out to do it. David Hockney
effective forces gravity known objects stuff
We account for one-sixth of the forces of gravity we see in the universe. There is no known objects accounting for most of the effective gravity in the universe. Something is making stuff move that is not anything we have ever touched. Neil deGrasse Tyson
effective exercise group major patients performed reducing seems showing standard studies symptoms
What the studies are showing is that exercise, at least when performed in a group setting, seems to be at least as effective as standard antidepressant medications in reducing symptoms in patients with major depression, James Blumenthal
effect george pockets retailers roll sales tried
When (former Gov. George Ryan's) administration tried to roll back the sales tax, it just went into the pockets of refiners and retailers and had no effect on prices, Steve Brown
effectiveness too-much loses
If you do too much it's going to lose its effectiveness. Bob Ross
fools-and-foolishness good mix silly
Mix a little foolishness with your prudence: it's good to be silly at the right moment. (Odes, bk. 4, no. 12, l. 27) Horace
fools-and-foolishness lovely mix moment serious silly
Mix a little foolishness with your serious plans; it's lovely to be silly at the right moment Horace
fools-and-foolishness four pride taxed taxes-and-taxation three twice
We are taxed twice as much by our idleness, three times as much by our pride and four times as much by our foolishness. Benjamin Franklin
fools good guess guy respectful saw steve suffer
I never, ever, saw the evil Steve Jobs. He was always the most well-mannered and respectful guy I knew. And we got to be pretty good friends. He didn't suffer fools gladly. I guess he didn't think I was a fool. Nolan Bushnell
fools hold idlers lay men mortal work
Tomorrow is the day when idlers work, and fools reform, and mortal men lay hold on heaven. Persius
fools-and-foolishness money
A fool and his money are soon parted. Thomas Tusser
fools-and-foolishness metals pocket precious uses
RHADOMANCER, n. One who uses a divining-rod in prospecting for precious metals in the pocket of a fool. Ambrose Gwinett Bierce
fools itself life revenge sweeter
Revenge is sweet, sweeter than life itself - so say fools Juvenal Juvenal
fools men tools
Men have become the fools of their tools Henry David Thoreau
half linux firsts
I was Computer Shopper's linux columnist for more than half a decade, from the late 90s onwards. Yes, I know about Linux. (My first review of a Linux distro in the press was published in late 1996.) Charles Stross
half empty gods-will
If I empty out half of my life, God can only fill half...God will fill as much of us as we allow Him to fill. Aiden Wilson Tozer
half safe matter
There are many different kinds of radioactive waste and each has its own half-life so, just to be on the safe side and to simplify matters, I base my calculations on the worst one and that's plutonium. David R. Brower
half intensity played second slow
We started slow today. In the second half we played with better intensity than we did in the first half. Linda Flohr
halfway michigan respecting seven state ten
We are at the turn, we are halfway around the track. It's just about respecting Michigan State and approaching like we have the other seven (Big Ten games). Kristy Curry
halftime hard played struggled
We struggled a little and they made it very hard to penetrate the middle. We made some adjustments at halftime and played better. Jim Mott
half pulled second
We started off slow, ... but in the second half we really pulled away. Robert Bates
half missing three top
We started each half missing a wide-open lay-up, and that kind of set the tone. My top three scorers couldn't find the basket. Dean Montzingo
half period second spent team wears
We spent the whole second period in the box. It wears half the team down. We can't be doing that. It kills us. Jeff Carter
inches esteem
Whenever you get one inch above the ground in your own esteem, you are that inch too high! Charles Spurgeon
inches
We're inches away from getting (the leases) completed. Bill Ryan
inches lower maybe six three
We're going with about three to six inches for the area, maybe more on the lower end of that range. John Gresiak
inch price square ticket
The price of the ticket is exhaustion. Look at the view. And I can see every square inch of the track. Andy Murphy
inch love miles six thousand
Love is a thousand miles long but comes in six inch installments. Unknown
inches
She's only about 41/2 inches from the automatic. Aaron Nida
inch looked nine
I like the idea of working in an album-sized chunk, you know, and I never looked at Nine Inch Nails as a project that would be a hit-driven, single-based kind of thing. Trent Reznor
inches
I had four compression fractures in my spine. They were repaired, but it cost me two inches of height. Tom Brokaw
inch mortgage percent rates
Mortgage rates may inch up, but I don't see them getting back up to 8, 9 or 10 percent for a long time. Brad Monroe
innocent crime contradictory
You don't have many suspects who are innocent of a crime. That's contradictory. If a person is innocent of a crime, then he is not a suspect. Edwin Meese
innocent shots deserve
The more innocent they are, the more they deserve to be shot. Bertolt Brecht
innocent-person justice long
That it is better 100 guilty Persons should escape than that one innocent Person should suffer, is a Maxim that has been long and generally approved. Benjamin Franklin
innocent nobody people planning since
Since 1999 we've had 100,000 innocent people murdered in America. But nobody is planning on commemorating all those people killed. Michael Paranzino
innocent people proposal punish
This proposal would punish people who are innocent of any wrongdoing. Bill Hamilton
innocent naive save simple trying
She's still the same old simple Cindy. She's just as innocent and naive as ever, just trying to save the world again. Anna Faris
innocent position proven until
We're kind of in the position that everybody's innocent until proven guilty. Rick Watson
innocent miss reason
We don't have little Miss Innocent who was sprayed for no reason at all. Steven Cohen
innocent-person murder human-nature
But I know human nature, my friend, and I tell you that, suddenly confronted with the possibility of being tried for murder, the most innocent person will lose his head and do the most absurd things. Agatha Christie
millions
I want to sell out arenas and sell millions of records. Katy Perry
millions
Let's just say it would be in the millions of dollars, F. Stone
millions pair restore surgery
A simple, well-proven surgery can restore sight to millions, and something even simpler, a pair of glasses, can make millions more see. Thulasiraj Ravilla
millions rainy sunday themselves
Millions long for immortality who do not know what to do with themselves on a rainy Sunday afternoon. Susan Ertz
millions people reason unified vote younger
So many millions of people don't feel like their vote has any meaning. There is no reason why younger people can't be a unified force. Mike Burkett
millions moment moments patient worthwhile
Not only will this make you treat each moment more preciously, but you will be more patient with yourself and with others, recognizing that there are millions of moments on the path to any worthwhile achievement. Menachem Mendel Schneerson
millions
If it's accessible by hundreds of millions of people, then it's as mainstream as it gets. Warren Ellis
millions politics
I'm in politics to make the lives of millions of Indians better. Nandan Nilekani
millions people somebody
I'm not sure who has the right to say that you have better taste than somebody else, because essentially what you're doing is calling millions of people morons. Simon Cowell
sincere substitutes ardent
There is no substitute for thoroughgoing, ardent, and sincere earnestness. Charles Dickens
since stimulated
We started giving presentations at practitioner conferences in 1986, and since then all of our derivatives research has been stimulated by contact with practitioners. John Hull
sincere loses
How can we lose when we're so sincere? Charles M. Schulz
since
I've always been interested in singing, and I've always been singing and dancing since I was little. Lindsay Lohan
since
What they have done is insufficient. It's now two years since the decision. Jonathan Todd
since uncharted
We're in uncharted territory. We haven't experienced something like this since the 1980's. John Felmy
since
You know, I didn't get to go to university because I've been acting since I was a kid. Isla Fisher
since time
I say to my mother all the time, 'You're the child.' And she says, 'Yeah, you're the mother.' I've been that way with her since I was 11. Kristy McNichol
since
Since I can't write the greatest American novel, I'm going to write the longest American novel. Thomas Steinbeck
toward wants
We're just working toward that now. Everyone wants to be in the same place at the end. Ryan Getzlaf
toward
For more than eight decades, Washington has been my hometown. My whole orientation is toward this place. Katharine Graham
toward victims violent
I think 'Dirty Harry' was probably sensitive toward the victims of violent crime. Clint Eastwood
toward
We still have a long way to go and we're still working toward that. Maurice Cheeks
towards
We are moving towards a new form of collective intelligence. Jane McGonigal
towards
I am very reactive towards everything. There are some who don't react at all, they absorb everything quietly, while I'd go all out and show my expressions. This is not part of some tamasha I do; I do it because it's part of my personality. To each his own. Preity Zinta
toward
I think a policy of isolationism toward Cuba is misplaced and hasn't worked. Rand Paul
toward vast within
One speck within vast star-space lyingAwoke, arose, resumed its clothing,And crawled another day toward dying. William Benet
toward western
It is going more and more toward the Western part of the world. Joseph Domenech