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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
almost fully investors money rate recommend simply since work
I almost always recommend investors get fully invested, since it's better to put your money to work than to let it simply track the rate of inflation. Louis Navellier
almost badly people provided schooling
The majority of people in Angola were not provided with any kind of schooling and were completely illiterate, very badly paid, and treated almost as slaves. Louis Leakey
almost begging ceremony good people private putting script
As a teenager, in my songbook, I used to script what my lighting would be like. I used to dance in my roo;, it was like putting myself in a trance, and making myself feel good about things, almost like a private ceremony of begging people to like you. Mika
almost body goes hip hurdles knee leg move split tells trainer
I hate leg exercises. I hate one-legged squats. I hate the hurdles and the split squats. I hate all the leg exercises. I know they help me, and I'm able to move around and don't have knee problems, and my hip doesn't hurt anymore, but when my trainer tells me I have to do them, I almost feel like my body goes into convulsions. Michael Strahan
almost along broken gets good hard pushed unless writer written
Nothing good gets written without the writer suffering along the way, in my opinion. Writing should be a pleasure, but unless you feel almost broken many, many times in the journey to a novel, you haven't pushed yourself hard enough. Mohsin Hamid
almost apologetic avoiding bars based brutal change exposed films flow money people suit truth
After 'Chandni Bar' there was a shutdown of such bars in Mumbai. After 'Page 3' people started avoiding such events. 'Traffic Signal' exposed the money flow through the mafia. I'm not apologetic about the brutal truth in my films. Almost 70% of my films are based on reality, and 30% I fictionalize or change to suit my film. Madhur Bhandarkar
almost fat great percentage product
The percentage of fat in this product here is almost 50 percent fat. But it's turkey. But because it's turkey, we think we're doing a great job. Margo Rodriguez
almost extremely following line sad
We are pretty much approaching the line of an almost Serb-free Kosovo, which is an extremely sad phenomenon. One exodus is following another. Kris Janowski
almost exception few odds people talked
We've already talked to people and it's completely safe, ... And with the exception of a few odds and ends, we're almost done. Chuck D.
baseball growing-up book
I didnt really grow up a comic book fanatic. I was a big baseball player, and my passion in life, in third grade, was collecting baseball cards. That was my childhood thing. Alan Ritchson
baseball kids player
I wanted to be a baseball player, naturally, but I wasn't good enough. I didn't know what I was going to do with my life. I just had a kind of energy, I was a fairly happy kid. Al Pacino
based behalf business customers decisions field includes line operating personnel regional responsibility restaurant ultimately
We want the line -- which for McDonald's includes our divisional and regional staffs, owner/operators and restaurant personnel -- to make decisions on behalf of customers based on field operating needs. The line ultimately has responsibility and accountability for our business success, Jack Greenberg
base fabulous fan football great
We want to see football in Ottawa. It's a great fan base and has some fabulous potential. But having said that, there's also reality. Ken Hildahl
baseball fun missing
If you're not having fun in baseball, you miss the point of everything. Chris Chambliss
baseball gone home-run
Back, back, back, back... Gone! Chris Berman
baseball hate yankees
Here at NBC there is just one more reason to hate the Yankees. Chet Huntley
baseball school games
I'm a very competitive person, whether it's school, baseball or even playing video games. David Price
baseball winning player
My goal on Earth is not to win a World Series or be the best baseball player who ever lived. That simply is not up to me because I have to wait and see if it is part of the Lord's plan. My goal is to follow the Lord and what he wants me to do so that someday I may enter His kingdom and receive everlasting life. David Murphy
began high injured marks student
I didn't know anything about acting, I didn't know anything about theater, but I was just an exceptional student at high school. I wanted to play ball; I'm going after a basketball scholarship and be a doctor. I got injured and my marks began to drop. Louis Gossett, Jr.
began begin gone rest
We started slowly, but then began to put things together. We were 3-9 to begin the year, but we have gone 9-4 the rest of the way. Brian Keith
began came collapse decision divers night operation parts pull rescue stopped structure tide
We stopped the rescue operation around 11 o'clock (Thursday) night, ... As the tide came in, the structure began to move, and other parts began to collapse again. We made the decision to pull our divers out. John Timoney
began dropping garbage gently goods nice people
We started from scratch. Immediately people began dropping things off - and they were nice things. Our goods are gently used. We are not a junkyard or garbage drop. Helen Scannell
began graduate nbc school thriving
When I was at graduate school in London, I began working at NBC News, which had a thriving documentary unit. Leslie Cockburn
began coast government island lifetime majority sort spent war
Sri Lanka is an island off the coast of India. There's two ethnicities there; one the Sinhalese, which is the majority and the government, and the minority, who are the Tamils. That's where I'm from. And my lifetime sort of began there; I spent 10 years, and I was there during when the war started and fled as a refugee to England. M.I.A.
began black book coast history interested single soldiers
Writing 'Native Guard,' I didn't know I was working on a single book. I began writing that book because I was interested in the lesser-known history of these black soldiers stationed off the coast of my hometown. Natasha Trethewey
began business create decipher developing dream life original qualities reality stuck tells work
I was commissioned in 2003 to create an original show, and began developing 'Upwake.' 'Upwake' tells the story of Zero, a modern-day business man, going to work with his life in a suitcase, stuck between dream and reality and not able to decipher the two. I wanted 'Upwake' to have the same audiovisual qualities as a movie would. Natasha Tsakos
began finished knocking kong moved next police soon work
While I was writing 'Stick Out Your Tongue' in Beijing, the police began knocking on my door again. As soon as I finished the book, I moved to Hong Kong so that I could work undisturbed on my next novel. Ma Jian
constantly destroyed rebuilding
Everybody's constantly being destroyed and rebuilding themselves, some more drastically than others. Michael Shannon
constantly education point
The point is professional enrichment, education, professional development. We are constantly learning. Susan Clark
constantly trying
Where I live, there's a lot of canyons. We're climbing constantly - we're like mountain goats. I'm just trying to get better at that. Joey Santiago
constantly facebook hang home huge influence looked text town
I have always looked up to my brothers. They are a huge influence on me. We constantly text and Facebook each other to give each other support. And we all hang out at home when we are in town together. Lexi Thompson
constantly learning means primarily protect remaining reminds threat toward vigilant win
Remaining vigilant toward this ever-present threat means constantly learning how better to protect ourselves. But primarily it reminds us that we must fight and win the war on terror, so that we do not have to fight it here in America. Mark Kennedy
constantly happier happiness hunt somewhat tiresome
I'm constantly on the hunt for insights about happiness or ideas about how to be happier - which probably makes me a somewhat tiresome companion at times. Gretchen Rubin
constantly redefine
You have to constantly redefine who you are. M.I.A.
constantly house noise open pounding whether
Whether my house was open or not, the noise was just as bad. ... It was like someone constantly pounding on the house. David Blair
constantly hit life moment motivating music whether
Whether it's soundtracking a moment in my life or just motivating me to hit the gym, I constantly have music playing. Even if it's just in my head. Reid Scott
facts may opinion
You may alter an opinion, but you cannot alter a # fact . Charles Spurgeon
facts embarrassing theft
[A] great embarrassing fact… haunts all attempts to represent the market as the highest form of human freedom: that historically, impersonal, commercial markets originate in theft. David Graeber
facts economic globalization
Globalization is a fact of economic life Carlos Salinas de Gortari
facts sacred comment
Comment is free but facts are sacred. C. P. Scott
facts republican celebrate
Well, I'm celebrating the fact that Republicans are doing better with women. Cathy McMorris Rodgers
facts sometimes sometimes-in-life
The plain unwelcome fact is that sometimes life stymies you. Aidan Chambers
facts accused resent
We resent being faced with facts we'd prefer to ignore as much as being wrongly accused of doing something we haven't. Aidan Chambers
facts investigation mark
A 'fact' merely marks the point where we have agreed to let investigation cease. Bliss Carman
facts film more-money
Im very happy with the success of short films. In fact, for me, the short films make more money than the features. Bill Plympton
infancy people
We're at the infancy stage, which is why we need to get more people involved. Bill Chambers
infancy-is brevity extremes
Infancy is what is eternal, and the rest, all the rest, is brevity, extreme brevity. Antonio Porchia
infancy-is able regression
Regression to the stage of early infancy is not a suitable method in and of itself. Such a regression can only be effective if it happens in the natural course of therapy and if the client is able to maintain adult consciousness at the same time. Alice Miller
infancy tenderness
Tenderness is the infancy of love. Antoine Rivarol
infancy people rough
This was the infancy of the industry... There were a lot of rough people around. Harry Reems
infancy-is literature poet
In the infancy of society every author is necessarily a poet Percy Bysshe Shelley
infancy-is rights mind
Habituated from our Infancy to trample upon the Rights of Human Nature, every generous, every liberal Sentiment, if not extinguished, is enfeebled in our Minds. George Mason
infancy-is trance hypnotic
We are all in a post-hypnotic trance induced in early infancy. R. D. Laing
infancy-is important genetics
The neuroscience area - which is absolutely in its infancy - is much more important than genetics. Leon Kass
modern poet should
How many modern transsexuals are unacknowledged shamans? Perhaps it is to poets they should go for counsel, rather than surgeons. Camille Paglia
modern apprentice
The modern technologist is less 'sorcerer' and more 'sorcerer's apprentice'. Barry Commoner
modern
I would like to do something modern and possibly funny. Dan Stevens
modern solutions
It is a Modern day, and these times need Modern solutions to Modern problems. Corin Nemec
modern-life plumber ifs
If I had it [life] to do all over again, I'd have been a plumber. Albert Einstein
modern outside presidency turned
When a presidency has been turned around, particularly the modern presidency, there's often an outside element. Fred Greenstein
modern presented words
There are no four-letter words or vulgarity. It's got modern themes, but they are presented in an old-fashioned way. Sally Deering
modern people
I don't think people want chains. People want modern conveniences, but they don't want chains. Dean Miller
modern success tolkien
The success that the Tolkien books had redefined modern fantasy. George R. R. Martin
others-opinions live-for-others opinion
When you live for others' opinions, you are dead. Carlos Slim
others-happiness blood people
I'm pretty much fixated on certain themes. Family, but it's family of choice as much as family of blood. Individuality, yes, but not at the cost of others' happiness. Be true to your friends. Remembering to find some wonder and hope in the world. Basically it boils down to: treat people like you'd like them to treat you, leave the world a little better than it was when you got here, respect others and stand up for those who can't stand up for themselves. Charles de Lint
others
Let the others have the charisma. I've got the class. George W. Bush
others search thyself
Search others for virtues, thyself for thy vices. Benjamin Franklin
others search self thy vices
Search others for their virtues, thy self for thy vices Benjamin Franklin
others though wounded wounds
He that wounds himself, even though he has not the right, is not culpable; but if others have wounded him, they are culpable. Akiva ben Joseph
others runs
When the others see how much he runs they will know they have competition. Rafael Benitez
others perish plot
Those who plot the destruction of others often perish in the attempt. Phaedrus
others proud today
But for others like me, today is a day to be proud of those we love. Owen Arthur
practicals
I'm practical. I see something, and I do it. China Machado
practical
She would not sugarcoat it for you. It was always very practical and real-world. Holly Tachovsky
practicals practical-life compelled
In practical life we are compelled to follow what is most probable ; in speculative thought we are compelled to follow truth. Baruch Spinoza
practical present sell town
What we need to do is sell this idea (to the town). It's not going to sell as a 'Save the Church' (proposal). The way we need to present it to the town is to find a sensible, practical use for this structure. Bruce Graham
practical sports
But as a practical matter, Detroit's the sports city in the country. Rick Snyder
practical
From a practical standpoint, most Americans don't live there. John Taylor
practical situations wisdom
Practical wisdom is what's called for in situations that have a moral dimension to them. Barry Schwartz
practical sing song
My mother and father come from that post-Depression, middle-of-World-War -I kind of thinking that says, 'Find a practical job. You know what I mean, Mr. Big Shot? So, you can sing a song ...' Al Jarreau
practical time
Theoretically, they still have time to do it, but from a practical standpoint, I don't think they are going to let it happen. Paul Hubbert
science uniforms taste
In science, reason is the guide; in poetry, taste. The object of the one is truth, which is uniform and indivisible; the object of the other is beauty, which is multiform and varied. Charles Caleb Colton
science disorder cures
No disorders have employed so many quacks, as those that have no cure; and no sciences have exercised so many quills, as those that have no certainty. Charles Caleb Colton
science mind cost
The acquirements of science may be termed the armour of the mind; but that armour would be worse than useless, that cost us all we had, and left us nothing to defend. Charles Caleb Colton
science tolerance religion
We are not clear as to the role in life of these chemicals; nor are we clear as to the role of the physician. You know, of course, that in ancient times there was no clear distinction between priest and physician. Alan Watts
science judging hammers
What happens if a big asteroid hits Earth ? Judging from realistic simulations involving a sledge hammer and a common laboratory frog, we can assume it will be pretty bad. Dave Barry
science animal mph
Scientists tell us that the fastest animal in the world, with a speed of 120 mph, is a cow dropped out of a helicopter. Dave Barry
science simple water
Here's a simple experiment that you might want to try if there is absolutely nothing else going on in your life. All you need is a cork, a bar magnet, and a pail of water. Simply attach your magnet to your cork, then drop it into the water, and voilà (literally, "you have a compass")-you have a compass. How does it work? Simple. Notice that, no matter which way you turn the bucket, the cork always floats on top of the water (unless the magnet is too heavy). Using this scientific principle, early hardy mariners were able to tell at a glance whether they were sinking! Dave Barry
science years careers
I ... began my career as a wireless amateur. After 43 years in radio, I do not mind confessing that I am still an amateur. Despite many great achievements in the science of radio and electronics, what we know today is far less than what we have still to learn. David Sarnoff
science oxygen breathe
Freedom is the oxygen without which science cannot breathe. David Sarnoff
short-life light long
Time is short. Eternity is long. It is only reasonable that this short life be lived in the light of eternity. Charles Spurgeon
short-life long way
Better to have a short life that is full of what you like doing than a long life spent in a miserable way... Alan Watts
shortcuts
There are no shortcuts. NONE. Mark Cuban
shortcuts
There is no shortcut to anyplace worth going. Beverly Sills
short-life years today
We foolish mortals sometimes live through years not realizing how short life is, and that TODAY is your life. Edith Schaeffer
short time
We have to get something going and have a short time to get there, ... I couldn't go out like that. If you're going to go back in, do something good. Brett Favre
short-life fire new-life
All roads for me lead back to Mozart. In his tragically short life, he breathed new life, fire and meaning into every form of music that existed in his time. Charles Hazlewood
short-life acceptance medicine
A saying from the area of Chinese medicine would be appropriate to mention here: "One disease, long life; no disease, short life." In other words, those who know what's wrong with them and take care of themselves accordingly will tend to live a lot longer than those who consider themselves perfectly happy and neglect their weakness. So, in that sense at least, a Weakness of some sort can do you a big favor, if you acknowledge that it's there. Benjamin Hoff
short-life length width
I [prefer] a short life with width to a narrow one with length. Avicenna
statesman
Now I know what a statesman is; he's a dead politician. We need more statesmen. Bob Edwards
theory
The classical theory of omniscient rationality is strikingly simple and beautiful. Herbert A. Simon
theory
Was Einstein's theory good? Relatively. Bo Burnham
theory observation
Observation always involves theory. Edwin Powell Hubble
theory understood convinced
Einstein explained his theory to me every day, and on my arrival I was fully convinced that he understood it. Chaim Weizmann
theory
My theory. Music can fix anything. Anything. Asa Butterfield
theory
Everybody has a theory. Daniel Handler
theory precision unified
A unified theory would put us at the doorstep of a vast universe of things that we could finally explore with precision. Brian Greene
theory
The oldest theory of contract is I think negative. Frederick Pollock
theory therefore trivial
If string theory is a mistake, it's not a trivial mistake. It's a deep mistake and therefore kind of worthy. Lee Smolin