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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics.
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online.
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services.
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts.
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters.
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here,
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof.
allowed available concern consumers dependent fast federal information interpret leverage manage model private sector send soon totally
We want to totally reconfigure this model so that the purchasers have available information before they make a purchase. Our concern is how soon can consumers get the info how soon can NMVTIS get the information. If we're dependent on federal agencies, we're not going to get it as fast as if the private sector is allowed to leverage that info manage it and interpret it and send it back out.
allowed although clueless far following gigs killer producers resume suddenly
I had done a couple of plays, but I was a clueless boob. 'Cosby' allowed me to have something on my resume that was real and then the producers of 'Guiding Light' let me play a preppy killer just the following month. Suddenly I had two gigs on my resume that made me look like a real actor, although I was far from it. Michael Weatherly
allowed pleasure
The pleasure is in being allowed to play in so many different sandboxes. Julie Andrews
allowed creep necessary
We've allowed those things to creep back. They are not necessary and should not be allowed.
allowed football loan needs
We've allowed him to go out on loan because he needs to play some first-team football, Alan Curbishley
allowed benefits bring business companies services sure
We, U S West, are not allowed to be in the long-distance business today. But we wanted to make sure that we could bring the benefits of services of companies like Qwest to our customers.
allowed defense stops
We started to get some defense stops and that allowed us to run.
allowed stuff
We started out well, and then when we made substitutions and allowed them to get stuff going.
allowed double played running slower stopped
We stopped running and played at a slower tempo, which allowed them to sag in and double team.
assumed audience clubs girlfriend people stage worked
The people who worked at the clubs just assumed I was a tagalong girlfriend or groupie. I'd get up on stage and the audience was just like, 'Show me your tits!' I had nothing to show anyway. Gwen Stefani
assumed coming found surprises
We always assumed he was coming here. When we found out, it was like, 'Wow!' But nothing surprises me anymore. It's a business. Hugh Douglas
assumed led totally
We were totally in Chicago's position. We led the whole way, and for a long time, it was just assumed that we were going to play in the postseason. Tim Salmon
assumed buy came lived markets people stylist
When I was a child, I lived in Morocco, and I would always buy a lot of beads from the markets and to make jewellery for friends. Later, at 18, I would do my own clothes and make my own patterns. When I first came to New York, people just assumed I was a stylist because I was so into fashion.
assumed coming dressed men
We would see nothing but men coming in and trashy dressed women. We just assumed that that's what it was.
assumed chemical definite far knew might production single therefore
We knew they had them, ... We had some very definite locations, particularly the production facilities... As far as the front-line ammo depot and where they might and might not have been located, we didn't know, and therefore we assumed every single one of them had chemical weapons. Norman Schwarzkopf
assumed longer people performed position remain took
There are people out there who, when they took their desks, assumed they could remain in their position as long as they performed well in that position. That is no longer the case. Mike Mason
assumed broke
What we assumed was it broke up because it sank. Now we know it sank because it broke up. David Brown
assumed authors exotic great order traveled
When I was young, I assumed that authors must have traveled the world or done exotic things in order to tell great stories. Kevin Henkes
certainly continued obviously president relationship white
I certainly know that this relationship could not have continued the way it did, when I was at the Pentagon and the president was obviously at the White House, without Betty. Monica Lewinsky
certainly chinese doctors filtered following four gotten government individual latest listed manual medical ordinary people perceive profession raid shows step until version
Until about four years ago, the Chinese medical profession was still following a version of the diagnostic manual that still listed homosexuality as an illness. That has also changed, but that may not have filtered down into how individual doctors or just ordinary people perceive it. Things have certainly gotten better, though, but this latest raid shows that the government can still step back, as well as forward.
certainly council full impose preparing resolution sanctions
We are preparing a resolution for the full council to adopt. It would impose the sanctions. It's a down payment, and certainly not the end of the sanctions process. John Bolton
certainly china fast growing markets outside products sell
There are certainly very high-growth markets outside the U.S.. China is the fourth-largest market in the world for Dell to sell its products and we're growing fast there. Michael Dell
certainly days glory growth microsoft prospects solid
There are certainly some solid growth prospects for Microsoft but it's not going to be the glory days again. Alan Davis
certainly love sarah work york
There are certainly some artists in New York that I would love to work with. One is Sarah Michelson. David Hallberg
certainly challenges issues people pursuing system
There are certainly issues that keep people from pursuing hate-crime charges. It's a system that's fraught with challenges because of the under-reporting.
certainly closely continue extremely threat watching
There are certainly hundreds of individuals who we have been watching very closely and continue to watch extremely closely ... because of the threat they offer, Charles Clark
certainly concerns fully human rights serious
There are certainly human rights concerns. Very serious human rights concerns that I would like to have fully clarified,
charity christianity
There can be no Christianity where there is no charity Charles Caleb Colton
charity
You cannot separate charity and religion.
charity excitement pleasure
There are not a few among the disciples of charity who require, in their vocation, scarcely less excitement than the votaries of pleasure in theirs. Charles Dickens
charity great-things involved
IIFA is always involved in charity, and that's why it's a great thing that I am a part of IIFA and will continue to work along with them. Akshay Kumar
charity philanthropy opium
Charity . . . is the opium of the privileged. Chinua Achebe
charity legs stools
Hope is a leg of a 3-legged stool with Faith and Charity. Dieter F. Uchtdorf
charity faith-hope-and-charity
The things we hope for lead us to faith, while the things we hope in lead us to charity.
charity favors begging
It is not begging but the beggar, who has forfeited favor with the elect. Agnes Repplier
charity degradation hunger
For those who are not hungry, it is easy to palaver about the degradation of charity ... Charlotte Bronte
confused real dope
I was playing a part of someone dealing dope on a street corner - and there was a guy actually dealing heroin right there. I looked at him, he looked at me, and I got real confused. Al Pacino
confused confusion ego
In the process of burning out these confusions, we discover enlightenment. If the process were otherwise, the awakened state of mind would be a product dependent upon cause and effect and therefore liable to dissolution. Anything which is created must, sooner or later, die. If enlightenment were created in such a way, there would always be a possibility of ego reasserting itself, causing a return to the confused state. Enlightenment is permanent because we have not produced it; we have merely discovered it. Chogyam Trungpa
confused appreciate people
A great deal of chaos in the world occurs because people don't appreciate themselves. Having never developed sympathy or gentleness toward themselves, they cannot experience harmony or peace within themselves, and therefore, what they project to others is also inharmonious and confused.
confused believe writing
I believe people instinctively know that about writing, yet people get confused about that when it comes to acting. Chiwetel Ejiofor
confused ideas done
I have so many ideas; there are so many things that need to be done, so many possibilities, you know; one is terribly excited, but at the same time, you're almost confused, because you don't know where to begin.
confused thinking air
Do you know anyone who hasn't changed his mind? This door was a tree, then it will be firewood for someone, then it will return to air and earth. We're all like that, constantly changing. It's simply honest to report that you've changed your mind when you have. When you're afraid of what people will think if you speak honestly, that's where you become confused. Byron Katie
confused mind stories
He tried to reconstruct the story in his mind, but it kept getting confused, bleeding into itself like watercolors. Catherynne M. Valente
confused people ankles
When a liver becomes cirrhotic, those are the common complications. We see that the patients have bleeding from their stomach and intestines. They have abdomens that become full of fluid. Their ankles swell with the same type of fluid, and they also can become confused and not themselves. Those are kind of the main things that we see when people get end-stage liver disease and have cirrhosis. John Roberts
confused war winter
We talk about spreading democracy and freedom all over the world, but they are to us words rather than conditions. We haven't even got them here in America, and the farther we get into this war the farther we get away from democracy and freedom. Where is it leading us to, and when will it end? The war might stop this winter, but that is improbable. It may go on for fifty years or more. That also is improbable. The elements are too conflicting and confused to form any accurate judgment of its length. There may be a series of wars, one after another, going on indefinitely. Charles Lindbergh
death sovereign warp
Death is the only sovereign whom no partiality can warp, and no price corrupt.
death medicine literature
Death is the liberator of him whom freedom cannot release, the physician of him whom medicine cannot cure, and the comforter of him whom time cannot console.
death hands body
The hand that unnerved Belshazzar derived its most horrifying influence from the want of a body, and death itself is not formidable in what we do know of it, but in what we do not.
death two sound
Death is like thunder in two particulars; we are alarmed, at the sound of it; and it is formidable only from that which preceded it.
death tears world
When death strikes down the innocent and young, for every fragile form from which he lets the panting spirit free, a hundred virtues rise, in shapes of mercy, charity, and love, to walk the world and bless it. Of every tear that sorrowing mortals shed on such green graves, some good is born, some gentler nature comes.
death eye giving
To close the eyes, and give a seemly comfort to the apparel of the dead, is poverty's holiest touch of nature.
death universal-truth universal
Death is a mighty, universal truth.
death fire mad
Keep out of Chancery. It's being ground to bits in a slow mill; it's being roasted at a slow fire; it's being stung to death by single bees; it's being drowned by drops; it's going mad by grains.
death waiting-rooms immortality
Death is the waiting-room where we robe ourselves for immortality. Charles Spurgeon
difficult productivity
Productivity is notoriously difficult to predict. Alan Greenspan
difficult given nine team teams
The one thing we like about our team over most teams we play is our depth. We play nine guys, and any one of them can go big on you on a given night. I think we're a difficult team to scout.
difficult experience gains good leadership players providing
The pluses are that (Gordon) is a good player. He is going to be one of the better players in the league. If he gains more experience he will be really good, he has had some difficult times and has been providing good leadership as a freshman.
difficult road
We are a little fatigued. It's been a difficult road trip.
difficult nearly perfect riders several today wind
Where the wind made it difficult for several riders Saturday, today was nearly perfect for the runners.
difficult liberate lord path shall street
Where the path is difficult and the street is narrow, there the Lord shall liberate you
difficult
I was just used to being in shape, and getting out of it was really difficult for me. McKayla Maroney
difficult movies
I've been told my movies are difficult to market. Nicolas Roeg
difficult except hard headline icon journal knew loved people pinpoint stands start talk talking worked
When you talk about an icon and a legend, an extraordinary individual, as well as a people's person, it's difficult where to start about the man. He was the kind of person where all you would have to say is Amby and people knew who you were talking about. People loved him. On the day of his passing, the headline in the (Providence) Journal read, A one, and last, of a kind. In all of the years that I worked with Amby, it's hard to pinpoint what stands out the most, except that he was always there. Jim Norton
finished one-thing
One thing is about to be finished, but here is something that is only begun. And while I live it will continue Alan Paton
finish games months second short six spring training won work
We've won it before, and anything short of that is failure. You don't work the whole off-season, spring training and six months of games to finish second or third. If you don't win, you should feel it's a failure. Derek Jeter
finish hear hopefully mean ok running talked track
We've already talked about that and they're OK with that. I want them to hear that from me and let them know I'm going to finish what I started. Hopefully that'll mean we're running track into May.
finish
We started together, and we are going to finish together.
finished slow
We started out kind of slow but we finished strong.
finishing interest knows
Actually, I have an interest in finishing my Ph.D., but I just know I never will. David Duchovny
finishing planning
I'm planning on finishing the Gospels at some point.
finished great hesitant oh risks seen studios yeah
Well, the studios don't really want to take those risks right off the bat. They'll take the risk after they've seen the finished product and say oh yeah we want that. This is a great film but they are hesitant to take the risk when you just see it on paper. Nia Long
finish projects
When I was in office, as a trustee and mayor, there were projects that were not finished. I just feel like I didn't finish what I started.
learning enemy safe
It is always safe to learn, even from our enemies; seldom safe to venture to instruct, even our friends.
learning ignorance knowledge
The greater the scientist, the more he is impressed with his ignorance of reality, and the more he realizes that his laws and labels, descriptions and definitions, are the products of his own thought. They help him to use the world for purposes of his own devising rather than understand and explain it. Alan Watts
learning evolution programming
Optimization hinders evolution. Alan Perlis
learning nouns programming
Any noun can be verbed.
learning thinking language
A good programming language is a conceptual universe for thinking about programming.
learning thinking knowing
A language that doesn't affect the way you think about programming is not worth knowing.
learning machines program
To understand a program, you must become both the machine and the program.
learn offspring reason
We want them to go back to doing what they used to do, which is migrate. The reason they migrate is for food. When they don't migrate, their offspring don't learn to migrate.
learn people stop tolerant
We want to stop profiling. The more that people learn about Islam, the more tolerant they become.
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
lessons management investment
A Lesson on Elementary, Worldly Wisdom As It Relates To Investment Management & Business Charlie Munger
lessons hard-lessons hard
The more hard lessons you can learn vicariously rather than through your own hard experience, the better.
life strong truth
There is nothing so strong or safe in an emergency of life as the simple truth.
life saying-goodbye expectations
Life is made of ever so many partings welded together.
life autism world
This is a world of action, and not moping and droning in.
life moral existence
Let us be moral. Let us contemplate existence.
life littles
Do all the good you can and make as little fuss about it as possible.
life people astonishing
It is astonishing how much more people are interested in lengthening life than improving it.
life soul prison
Life is the jailer of the soul in this filthy prison, and its only deliverer is death.
life happiness dark
Much too oft we make life gloomy-- When happy we might be, If we gathered more of sunshine, And not dark shadows see.
life distance journey
Evils in the journey of life are like the hills which alarm travelers upon their road; they both appear great at a distance, but when we approach them we find that they are far less insurmountable than we had conceived.
marriage stars wife
My wife, the star I steer by. David McCullough
marriage party talking
As you get older; you've probably noticed that you tend to forget things. You'll be talking with somebody at a party, and you'll know that you know this person, but no matter how hard you try, you can't remember his or her name. This can be very embarassing, especially if he or she turns out to be your spouse. Dave Barry
marriage remains engines
Marriage remains the most efficient engine of disenchantment yet invented. Caitlin Flanagan
marriage want married
When I'm married I want to be single, and when I'm single I want to be married. Cary Grant
marriage mass potential terrorism weapons
The potential marriage of weapons of mass destruction with terrorism is everyone's nightmare. Condoleezza Rice
marriage men village
As a walled town is more worthier than a village, so is the forehead of a married man more honorable than the bare brow of a bachelor. William Shakespeare
marriage carnival-rides carnivals
Marriage isn't a carnival ride. Aisha Tyler
marriage kids grandchildren
I'm most proud of the longevity of my marriage, my kids, and my grandchildren. If you don't have that, you really don't have very much. Bob Newhart
marriage rocks long
A marriage is like a long trip in a tiny row boat: if one passenger starts to rock the boat, the other has to steady it, otherwise, they will go to the bottom together. David Reuben
nearly politics turn
You have to turn a blind eye to politics in nearly all Westerns. Clive Sinclair
nearly town work
Nearly all our blokes are locals, but a lot of them work out of town during the week, Gary Roberts
nearly people screen
There are people who you see on screen and think, 'Wow, that's a slim person,' and in the flesh they look nearly dead. Romola Garai
nearly perfect rain
For rain fans, it's going to be a nearly perfect day.
nearly played solid stepped
Kendra stepped up and played a solid game, nearly getting a double-double.
nearly public
To date, every American citizen has nearly $27,000 in public debt riding on our backs. Paul Gillmor
nearly
What you do is not nearly as important as who you are.
nearly
It is so cold out there, my head nearly fell off. Mark McKinney
nearly
I think it's nearly impossible to write something fictional without having it be about yourself in some way or another. Jami Attenberg
opens sink sucked
As for Philadelphia, you know what it is like? Sink holes. You stand in the earth and it opens up and you're sucked down. I'm never going to escape Philadelphia.
opens plays
When we come out and he plays aggressive, that opens it up for other players. When he plays like that, the sky's the limit. Dee Brown
opens
She always opens it up to questions, comments, suggestions.
opens shirley
Shirley Temple opens doors for Shirley Temple Black. Shirley Temple
opens sort
When I go and teach, it sort of opens me up in some way. And when you're open, you're more receptive. Stephen Frears
opens stay wonderful
The Internet is a wonderful thing, but it opens the door to many crimes, so you have to stay ahead of it. Frank Abagnale
opens until
Until he opens up, there's nothing we can do.
opens talented welcome
We welcome that. Then it opens things up for our other talented receivers.
opens pushed screens stay studios three
Or, if it opens on three screens, it's going to stay on those three screens for much of the summer. He's not going to be pushed around like most studios are pushed around. Peter Bart
ordinarily
It's not just what you would ordinarily think of.
ordinarily witness
A summary witness is ordinarily a dispassionate presenter,
reason rhetoric foe
The press is the foe of rhetoric, but the friend of reason.
reason
Faith is led confidently to expect what reason would never suggest.
reason event-horizon lacking
We are alone. Live our lives, lacking anything better to do. Devise reason later. Alan Moore
reason accepting
Never ever accept 'Because You Are A Woman' as a reason for doing or not doing anything. Chimamanda Ngozi Adichie
reason take-me happens
Things happen for a reason. We'll see where life takes me from here. Buddy Rice
reason shares sold
The only reason I sold the 500,000 shares on Sept. 17, the only reason, was Sept. 11. Jeffrey Skilling
reason violent expeditions
The expedition of my violent love outrun the pauser, reason.
reason inequality seems
Do not banish reason for inequality; but let your reason serve to make the truth appear where it seems hid, and hide the false seems true.
reason
Love reasons without reason.
spanish written
I've always written about social concerns. My first book was about Spanish Harlem. Dan Wakefield
spanish-philosopher
Be content to act, and leave the talking to others. Baltasar Gracian
spanish-philosopher time withdraw
There is always time to add a word, never to withdraw one.
spaniards
He that trusts much Obliges much, says the Spaniard. George Herbert
spanish verbs
Sometimes you can do things with Spanish - like verbs and genders - easier than you can in English. Juan Felipe Herrera
span time
(The sequel) would span its own time period. You wouldn't have to see the first one to get it.
spanish
I know how to say 'faster' and 'defend' in Bosnian, Spanish and Creole.
spaniards fairs
I played a Spaniard. I looked about as Spanish as any other fair-skinned German. Lawrence Welk
spanish-inquisition inquisition
No one expects the Spanish Inquisition! Oscar Wilde
spouse
You can change your spouse, your friends but never your club. Adam Richman
spouse
What is a spouse for? Not to be your personal servant, certainly! Marly Youmans
spouse
A lot of times your spouse sees things about you that you don't necessarily see. Ted Cruz
spouse communicate persons
There is no lonelier person than the one who lives with a spouse with whom he or she cannot communicate. Margaret Mead