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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
american-athlete carry everyday player team
We want them to know what it's like to be a leader, what it's like to be a team player because those things carry on in everyday life. Troy Vincent
american-athlete chain drugstore
The point of that is, if you look at Walgreen's history, they've always been pioneers in the application of technology. They're the only drugstore chain that I know to have their own satellite. James Collins
american-athlete
We're in Manila. Come on, gorilla; this is a thriller. Joe Frazier
american-athlete bing singing
Why that would be like challenging Bing Crosby to a singing contest,wouldn't it? Ben Hogan
american-athlete mostly
I think it'll be an emotional day. It'll be exciting for me, mostly it'll be exciting for them. I'm not going to get to come here a lot, so, it'll be a special day, hopefully. Latrell Sprewell
american-athlete everybody
I know just one thing is those guys, KG and everyone, they're hungry. They want it bad. Sam's the only one that's had that, has the ring. Other than him, everybody else over there, we want it bad. Latrell Sprewell
american-athlete
I'm still going to have to go out and score, but defensively hopefully I can make them a little bit better. Latrell Sprewell
american-athlete great playing
Sam is there, Sam has been playing well, he has been doing great in camp. Latrell Sprewell
american-athlete guys
You guys know the way I play. And what's so ironic is, KG is the same way. I'm looking at him in practice and going, 'Wow, I'm always that guy,' you know? Latrell Sprewell
art children natural
Be natural my children. For the writer that is natural has fulfilled all the rules of art. Charles Dickens
art block food
To see the butcher slap the steak before he laid it on the block, and give his knife a sharpening, was to forget breakfast instantly. It was agreeable too - it really was - to see him cut it off so smooth and juicy. There was nothing savage in the act, although the knife was large and keen; it was a piece of art, high art; there was delicacy of touch, clearness of tone, skilful handling of the subject, fine shading. It was the triumph of mind over matter; quite. Charles Dickens
art school speech
Eloquence is the language of nature, and cannot be learned in the schools; but rhetoric is the creature of art, which he who feels least will most excel in. Charles Caleb Colton
art people dirt
Mrs Joe was a very clean housekeeper, but had an exquisite art of making her clenliness more umcomfortable and unacceptable than dirt itself. Cleanliness is next to godliness, and some people do the same by their religion. Charles Dickens
art philosophy ideas
We all draw a little and compose a little, and none of us have any idea of time or money. Charles Dickens
art prayer hate
Beware, I pray thee, of presuming that thou art saved. If thy heart be renewed, if thou shalt hate the things that thou didst once love, and love the things that thou didst once hate; if thou hast really repented; if there be a thorough change of mind in thee; if thou be born again, then hast thou reason to rejoice: but if there be no vital change, no inward godliness; if there be no love to God, no prayer, no work of the Holy Spirit, then thy saying "I am saved" is but thine own assertion, and it may delude, but it will not deliver thee. Charles Spurgeon
art children crowns
Alas, if our children lose the crown of life, it will be but a small consolation that they have won the laurels of literature or art. Charles Spurgeon
art doubt whispering
Come boldly, 'O believer, for despite the whisperings of Satan and the doubtings of thine own heart, thou art greatly beloved. Charles Spurgeon
art honesty believe
I firmly believe that the only reason why I'm on this planet, the only reason why I live, breathe, and exist is, that it's my duty to be as honest as possible in my art. Alanis Morissette
civilization luxury selfishness
A semi-civilized state of society, equally removed from the extremes of barbarity and of refinement, seems to be that particular meridian under which all the reciprocities and gratuities of hospitality do most readily flourish and abound. For it so happens that the ease, the luxury, and the abundance of the highest state of civilization, are as productive of selfishness, as the difficulties, the privations, and the sterilities of he lowest. Charles Caleb Colton
civilization saws ends
I saw someone peeing in Jermym Street the other day. I thought, is this the end of civilization as we know it? Or is it simply someone peeing in Jermyn Street? Alan Bennett
civilization solitude going-out
Modern civilization is so complex as to make the devotional life all but impossible. It wears us out by multiplying distractions and beats us down by destroying our solitude, where otherwise we might drink and renew our strength before going out to face the world again. Aiden Wilson Tozer
civilization doubt moral
I have no doubt that historians will conclude that we of the twentieth century had intelligence enough to create a great civilization but not the moral wisdom to preserve it. Aiden Wilson Tozer
civilization stuff jingles
Freedom!- is the fatuous jingle of our civilization, but only those deprived of it have the barest inkling re: what the stuff actually is. David Mitchell
civilization creating alternatives
It's a difficult business, creating a new, alternative civilization. David Graeber
civilization climate-change humans
More than any other time in history, the 1990s will be a turning point for human civilization. David Suzuki
civilization age generations
Generations do not age. Every youth of any period, any civilization, has the same possibilities as always. Cesare Pavese
civilization savages fragility
They do not understand the fragility of civilization and the constant nearness of savage nature. Camille Paglia
crude listening seemed
With these reissues, listening to these tapes, it seemed very crude to me. There's no way I'd ever want to play like that again. Thurston Moore
crude giving lack patient problem wrong
We're giving the patient the wrong medicine. The problem is not the lack of crude oil. Fadel Gheit
crude drive events floor high market price pricing seeing short term though
Short term events like this which are unpredictable can drive a high price floor for crude prices. That is why we are seeing pricing in the high 50s even though the market is well supplied. Victor Shum
crude deferred expect falling lead next oil season since turnaround weeks work
Since many refineries deferred their maintenance work after the hurricanes, we expect this year's turnaround season to be particularly heavy. As a result, crude oil consumption by refiners should decrease, which could over the next weeks lead to falling oil prices. Tobias Merath
crude oil pressure
mitigated some of the upward pressure on crude oil prices. Jason Schenker
crude full high low market recipe strong
We have high crude prices. We have low inventories. We have strong demand. All of that would be a recipe for a taut market even with refineries (running at full capacity). Daniel Yergin
crude dichotomy economic high market path political price remains resistance structural until
The real dichotomy in this market is that crude inventories are very high and that could make for some violent, back-and-forth price action. For the foreseeable future, the path of least resistance remains up until there is a significant structural economic or political shift. Michael Fitzpatrick
crude cooks
I'm a rather crude cook. Dominic West
crude high oil price prices pump reason record
The price of crude oil is a big reason pump prices are in record high territory. Geoff Sundstrom
earlier heads hit looking proved toward
We're in a funk, definitely. I don't even know what to say. We can hit the ball. We proved that earlier in the season. But we're still confident. We've got our heads up and we're looking toward tomorrow. Matt Bowman
earlier gone gotten hit maybe warm
When he first hit it, I thought it was probably gone. It had just gotten cold. Maybe earlier when it was warm it would have gone out. Jermaine Dye
earlier feet felt pick year
We felt like we could pick up 94 feet - something we were doing earlier in the year when we had more bodies. Doc Sadler
earlier force issue
We're going to have to force the issue a little earlier than we wanted to. Steve Sherman
earlier employ gifts less pastor presidency
The earlier practice of the Church had been more or less to employ in worship under the presidency of the pastor or pastors, the gifts of the congregation. Robert Rainy
earlier girls hope maria open today
Like everyone else, they wanted to take Hope and Maria out of the game. I told the girls earlier today that someone is going to get open shots. Bret Tuetken
earlier kids michael
A lot of my friends were a lot into theatre a lot earlier than I was. A lot of my friends were kids who were in The Broadway Kids and the kids auditioning for Gavroche in 'Les Miz.' I was never that kid. I was weaned on Michael Jackson. Not literally, because that would have been odd. Erich Bergen
earlier might recession recovery vigorous
We might be out of recession already. The recovery could be more vigorous than earlier anticipated. Ken Goldstein
earlier good last supported year
She had a good year last year. If we could have supported her at all with some runs, especially earlier in the year, she would have had a much better record. Mike Harper
early lots market options people uniquely watch work
Try out lots of different options early in your career. Then watch the responses: how you feel, what the market values, what people appreciate about you. It's the only way to find work that's uniquely right for you. Lisa Gansky
early pleased signals
We are pleased with the early signals this year, John Eyler
early fourth freshmen quarter
We started subbing and early in the fourth quarter we had some freshmen on the field. Pat Scelza
early easy good job maintain playing road start tough
We started really well. Playing on the road isn't easy and getting a good start is so important and we really did a good job early on. We didn't maintain the intensity, but after a start like that, it is tough to keep up that level. Curt Fredrickson
early executing good half looks missed open second shots
We started out well, executing and getting open shots in rhythm. They crawled back into it right at the end of the first half, and in the second half we got some good looks early but missed them. Jack Schrader
early guys identify season struggled team trying
We struggled early on with our team trying to identify their roles. That is what the early season and midseason tournaments are for. The guys have done that. Chris Renner
early five hopefully key looking middle peak reason row time valley win
We are looking to make it five in a row after this match. The key is to peak at the right time and to hopefully peak in the early to middle of April. There is no reason why we can't win the Valley this year. Greg Kennett
early held rest struggled
We struggled early but otherwise, we held our own the rest of the way. Curtis Brown
early fixing turkeys
We started fixing the place up, probably in October. We put our first turkeys on the place in early December. Rich Rogers
egypt order greek
Elegance is reduction, simplification, condensation. It is spare, stark, sleek. Elegance is cultivated abstraction. The source of Greek and Roman classicism - clarity, order, proportion, balance - is in Egypt. Camille Paglia
egypt japan white
Imperialism and slavery are no white male monopoly, but are everywhere from Egypt, Assyria, and Persia to India, China and Japan. Camille Paglia
egypt personality lines
Capitalism, gaudy and greedy, has been inherent in western aesthetics from ancient Egypt on. It is the mysticism and glamour of things , which take on a personality of their own. As an economic system, it is in the Darwinian line of Sade, not Rousseau. Camille Paglia
egyptians reverse
We approached the Egyptians first. It was kind of the reverse of normal. ... At first they had to be convinced. Peter Lacovara
egypt recipes ingredients
It’s not that Egypt doesn’t have a recipe for a democratic transition. It seems to lack even the basic mental ingredients. David Brooks
egypt white giving
President Obama invited John McCain to the White House to give his opinion on Egypt, specifically what it's like to be a mummy. Bill Maher
egypt fifth land officers seven
Let Pharaoh do this, and let him appoint officers over the land, and take up the fifth part of the land of Egypt in the seven plenteous years. Bible Bible
egypt iran america
Even non-democratic allies no longer trust America. Barack Obama has alienated our most important and longest standing Arab allies, Egypt and Saudi Arabia. Both the anti-Muslim Brotherhood and the anti-Iran Arab states have lost respect for him. Dennis Prager
egyptians meetings order others since worked
Since then, I have worked tirelessly in all my meetings with Egyptians and others in order to do so, Ariel Sharon
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
productive-work people mud
I hope I don't sound like an old-fashioned stick-in-the-mud, but when I hear about people making vast fortunes without doing any productive work or contributing anything to society, my reaction is: “How can I get in on that? Dave Barry
products quarter talked
There are some big inventories out there. The new products that they have talked about aren't out for another quarter or so. So it's probably going to be more of the same for some time. Bob Turner
products
It is necessary that I am viewed as a product. I am a product. Ayumi Hamasaki
production
We're getting production from different people. They're working well as a team. Ed Miller
product ready search serious
We're ready to compete. We're very serious about this. Search evolves. We have a product that I think is part of that. Barry Diller
products putting quality shelves sure
We want to make sure we're only putting safe, quality products on our shelves for our customers. Karen Burk
product
The product is out there. It's not necessarily right, and it's not necessarily wrong. It's just the idea that was generated. Matt Flynn
production recording step
The production and recording is a big step up. Grayson White
productive-life people good-relationship
Psychology, unlike chemistry, unlike algebra, unlike literature, is an owner's manual for your own mind. It's a guide to life. What could be more important than grounding young people in the scientific information that they need to live happy, healthy, productive lives? To have good relationships? Daniel Goldstein
proposing simple
We're proposing a very simple LNG import terminal, Robert Wyatt
proposing silver washington
If we had a silver bullet, we would be proposing it to Washington right now. Ken Cohen
proposing step
This year, what we are proposing is one more step in the process. Dennis Godfrey
ripe time
The time was ripe for Flower. The vibe was right. Jody Watley
ripe
When I was almost 13 I was ripe for religion. I was actually just plain ripe. Kathie Lee Gifford
surprising
I think the most surprising thing about giving is it takes a while to find out what you're really interested in and what you really want to do. Marc Benioff
surprising work
As an actor, the thing I want to do to an audience is always be ahead of them and always be surprising in the work without deviating from the writer's intention. Steve Bisley
surprising
We want things to be beautiful, surprising to see, but they also have to be functional. One without the other doesn't make any sense. Philip Schiller
surprising
Everything is surprising, rightly seen. A. S. Byatt
surprising
I can get really obsessive. I like writing many drafts, and I try not to because it is very time-consuming, especially when you're working on a novel. But I do like to take a story and reorder it, put things in different places. This allows me to see things in a new and sometimes surprising way. Carol Windley
surprising truth
Here is the surprising truth: It's often easier to make something 10 times better than it is to make it 10 percent better. Astro Teller
surprising
I was shocked. I won't say it was crushing, but it was surprising and disappointing. Michael Hein
surprising
If you want a machine to be able to interact with people, it better not do things that are surprising to people. Rodney Brooks
surprising
The thing that's been really surprising about the evolution of Facebook is - I think then, and I think now - that if we didn't do this, someone else would have done it. Mark Zuckerberg