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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
along information loved objective pass
We want them to get precise, objective information so they can pass it along to their other loved ones. Humberto Moreira
along job love movies people
You can make movies and not particularly get along with the people you're working with but, when they say 'Action,' your job is to make it look like you're in love. Luke Bracey
along beating becoming bottom carrot enormous great harder incentives move people trajectory trying
For people who are at the bottom economically, the world is becoming a harder and harder place. And yet the incentives to become rich are so great because enormous amounts of wealth are being accumulated. And so those two things, that carrot and stick, are beating people along this trajectory of trying desperately to move up in the world. Mohsin Hamid
along amount appreciate chose corey defensive depth five great last opportunity sign talent
We appreciate all that Corey has done for this organization over the last five years. With the great amount of depth and talent we have along the defensive line, we chose to give Corey and opportunity to sign with another team. Andy Reid
along college commitment expand extending further future golf great high junior ongoing players programs proud relationship school support
We are proud to expand our support of junior golf by extending our relationship with the Junior World Championships. Our sponsorship of this prestigious event, along with our ongoing support of high school and college programs around the country, further demonstrates our commitment to the players who are the future of this great game. George Fellows
along barrier center concrete dropped heard highway horror lane proposed stories type
We've all heard horror stories about a proposed concrete barrier about to be dropped in the center lane along Southgate. The center median is necessary, but it won't be the concrete type used in highway construction projects. Richard Waugh
along announce construct corn ethanol highway location plans plant pleased sioux south
We are pleased to announce that Little Sioux Corn Processors, L.P., plans to construct an ethanol plant at a location south of Akron, Iowa, along Highway 12. Gary Tucker
along continue develop generation goal great improve looking moves next prospects rangers season
We are looking to develop the next generation of great Rangers players, ... Our goal is to continue to improve as the season moves along and to continue to develop the many great young prospects we have now. Glen Sather
along brand exciting forward fun hard looking team winning
We are looking forward to working hard and having a winning season. This should be an exciting team and brand of basketball. I think we will all have a lot of fun along the way. Ricky Stokes
alphabet box cares check design fear hard issue laundry list nature offend president problem run speeches state sun union
The problem with State of the Union speeches is that they are, by their nature and design, alphabet soup. It's hard to know what a president really cares about when they run down a laundry list and check every issue box under the sun for fear they will offend some constituency if they don't. Mark McKinnon
alphabet certain eleven placed sort vowel
Out of the simple consonants of the alphabet and our eleven vowels and diphthongs all possible syllables of a certain sort were constructed, a vowel sound being placed between two consonants. Hermann Ebbinghaus
alphabet artistic essential preserve rigidity
For designers, the rigidity of an alphabet presents a never-ending artistic challenge: How do you do something new and still preserve the letters' essential forms? Virginia Postrel
alphabet
We don't know. It will go to the Swahili alphabet or something else, Jim Lushine
alphabet beyond found imagination letter poking sort spell starts surprised
My alphabet starts with this letter called yuzz. It's the letter I use to spell yuzz-a-ma-tuzz. You'll be sort of surprised what there is to be found once you go beyond 'Z' and start poking around! Dr. Seuss
alphabet days good greek news
I don't think we're going to get into the Greek alphabet this year. The good news is it's still 56 days before it starts. John Williams
alphabet chant gaelic memory months remember room script seeing start
I'd just go into a room in my memory and just look around and start seeing things that I'd forgotten, like the alphabet on the blackboard in Irish, which we had to chant every day for months and months and months. I remember the Gaelic script and things like that. And this awful, putrid lavatory that we used outside." () Frank McCourt
alphabet english-mathematician eventually found full hour later rather screen shifting suddenly toy understood until
Eventually I found it had been working all along-but didn't show anything on screen until it had the first full page of text. I inserted 30 new lines, and suddenly my toy said 'hEllO woRlD'. An hour later I understood alphabet shifting rather better! Graham Nelson
alphabet good inception
From the inception of the alphabet organizations, they have been very, very selfish. It's never been about what's good for boxing. It's always been about what's good for them, specifically what's good for them financially. Steve Farhood
billion chinese life people remember
The people will always remember him, ... We have 1.2 billion people, but the life of every Chinese person is precious. Jiang Zemin
billion increase mp3 percent players sales sold video
We are projecting an increase in sales of MP3 players to $4.5 billion in 2006, with 30 percent of all MP3 players sold having video playback capability. Sean Wargo
billion gas prepared supply
We are prepared to supply 30-40 billion cu m of gas to China. Saparmurat Niyazov
billion bit china countries global happens increases nobody original population projection seems situations studied took total
We studied different countries around the world that are representative of different situations and took a look at where they'd end up. One thing that happens right away, which nobody seems to have thought of, is that the total global population increases dramatically. From an original projection of 8 billion we end up topping out at 10 to 11 billion. In many countries, this would have an enormous, and not necessarily positive, impact. For example, the idea that China would go from 1.5 to 1.8 billion, just because of this, is a bit frightening. Shripad Tuljapurkar
billions businesses pay state taxes
There are businesses in our state that make billions and pay no taxes at all. Bob Gammage
billion cash flow interested next phase seeing sit stardust together watching
We're interested in watching the next phase of high-rise condos going up, and we're interested in seeing how the Stardust comes together with their new $4 billion product. We have cash flow we can sit on while we're watching the market. Peter Feinstein
billion imagined incredibly inhabited virtual
We're incredibly excited to welcome the 500 millionth Poptropican into our virtual world. When we started in 2007, we never could have imagined that we'd see a day when half a billion avatars inhabited Poptropica. Jeff Kinney
billion octopus split
We split from our common ancestor with the octopus half a billion years ago. And yet, you can make friends with an octopus. Sy Montgomery
billion divine landed providence somehow spin sun
We spin around the Sun with 6 billion of us and somehow through divine providence we landed right here right now. Byron Dorgan
bits bob brian coming dylan hopefully lots sit song stuff together totally type
We've all got lots of different influences. We never sit down to write a song and say, 'This is going to be a Brian Eno type of song,' or 'This is a Bob Dylan song.' It's totally little bits of lots of different stuff that come together and hopefully it's something coming out of us that we're creating. Robbie Guertin
bits
There are bits of me in all my characters. Chris Lilley
bits complete groups information kinds lack offer recall situation small tire
There are some groups who say that Firestone's tire recall should be expanded. They offer small bits of information but lack the complete picture. These kinds of suggestions will make the situation worse. Helen Petrauskas
bits pieces tear wall
When you tear out insulation from the wall or something like that and it comes out in bits and pieces all you do is tear it all out. Greg Austin
bits case certain future longer might particular unemployed
I no longer say I'm unemployed. I say I'm unemployable. It's different. An unemployed suggests at a certain point in the future, you might be employed. That's not the case with me. I'm unemployable, and unfortunately, that's one of the bits of the web, in particular of Google. Norman Finkelstein
bits concerned helping process sure
With the little bits I have, no. I'm not concerned about that one bit. I'm more concerned with helping the process and making sure everything comes to the front. Pete Carroll
bits last
We're just hauling out the last bits of debris. Mike Riley
bits british-actor delighted receive suicidal thrilled
I won't say I wouldn't be grateful and happy and delighted and thrilled to bits to receive a nomination. But I wouldn't be suicidal if it didn't happen. Tom Wilkinson
bits dialogue doodle false fragments full lines messy process run single suddenly
My process is messy and non-linear, full of false starts, fidgets, and errands that I suddenly need to run now; it is a battle to get something - anything - down on paper. I doodle in sketchbooks: bits of ideas, fragments of sentences, character names, single lines of dialogue with no context. Ellen Klages
dna abbreviations strings
DNA is an abbreviation for deoxyribonucleicantidisestablishmentarianism, a complex string of syllables. Dave Barry
dna body messengers
DNA is the messenger which illuminates that connection,handed down from generation to generation,carried,literally,in the bodies of my ancestors. Bryan Sykes
dna numbers links
Scientists have established huge numbers of links between particular diseases and snippets of DNA, but in the great majority of cases, this has not yet been translated into treatments that can help cure patients. These treatments will come - tomorrow, or the day after. Charles C. Mann
dna born term
When you're born again, your DNA changes. You have the ability to understand God's terms. Bill McCartney
dna light speed
The electronic image is not fixed to any material base and, like our DNA, it has become a code that can circulate to any container that will hold it, defying death as it travels at the speed of light. Bill Viola
dna america volunteer
More young people are volunteering than ever before. More people are including service to others on their busy lives' to do list. The promise of America is embedded deep in our DNA, calling us to a much less shallow search for happiness and meaning. Arianna Huffington
dna sitting waiting
We're just sitting back, waiting for the DNA of this child. Jackie Cox
dna future
What we didn't have was a DNA that we really thought would be the future of Ford. Phil Martens
dna hell-raising catholic
I come from an Irish Catholic family, and hell-raising is part of the DNA. Brian Dennehy
genetics primarily study understanding
What I am primarily is a neurogeneticist: I use genetics to study problems in neurobiology. The one problem I study primarily... understanding of the sense of touch. Martin Chalfie
genetics pure rarely truth
The truth, it is said, is rarely pure or simple, yet genetics can at times seem seductively transparent. Iain McGilchrist
genetics plays strong
We can say genetics plays a strong role. Margaret Gatz
genetics process found
In no sense other than an utterly trivial one is reproduction the inverse of chemical disintegration. It is a misunderstanding of genetics to suppose that reproduction is only 'intended' to make facsimiles, for parasexual processes of genetical exchange are to be found in the simplest living things. Peter Medawar
genetics plays
We don't yet know if genetics plays a factor. Christopher Haiman
human-nature abstinence appetite
Subdue your appetites, my dears, and you've conquered human nature . Charles Dickens
human-nature lifeless permanent
The more a thing tends to be permanent, the more it tends to be lifeless. Alan Watts
humanity architect grey
Yes, Garnett Grey was an Architect. Were a psychoanalyst to approach him from behind, tap his shoulder, and say 'Humanity,' Garrett'd spin and respond, without hesitation, 'Solvable'. Chip Kidd
humanity
We cannot trample upon the humanity of others without devaluing our own. Chinua Achebe
humanity mud practicals
We cannot trample upon the humanity of others without devaluing our own. The Igbo, always practical, put it concretely in their proverb Onye ji onye n'ani ji onwe ya: 'He who will hold another down in the mud must stay in the mud to keep him down.' Chinua Achebe
humanity end-of-the-world world
Anticipating the end of the world is humanity's oldest passtime David Mitchell
humanity originality specks
Your turn has come to sift through the dreck of humanity for rare specks of originality David Mitchell
humanity states organized
The better organized the state, the duller its humanity. David Mitchell
humanity identity divorced
Our identity was bestowed upon us by God and when humanity rebelled against God, we were divorced from the source of our identity. In this vacuum, work can wrongfully become the source of our identity wreaking havoc on our lives and work. Work was never meant to carry the weight of our identity. David Kim
information asks
I only ask for information. Charles Dickens
information
We want to see how much information is forthcoming between now and the 7th. Charles Schumer
information increase intervention
My sustenance is information. My interventions are hidden. I increase as I learn. I compute, so I am. China Mieville
information seeking
We are always seeking new and better information. Mayor Barse
information points seen start worrying
We've already had some very worrying points of information which could have seen the start of the correction. Richard Davidson
information light obtain whether
Where they lived, how big they were, how much light they emitted, whether they even existed, we weren't sure. What we've done, we think, is obtain the first information about these stars. Alexander Kashlinsky
information listening ought truly
Where's our majority, they're the one's who ought to be here listening to this. This is information we really and truly ought to be concentrating on. Bill Summers
information knowledge lost wisdom
Where is wisdom we have lost in knowledge? Where is the knowledge we have lost in information? T. S. Eliot
information you-like-it ownership
When you post something, when you text something, you lose ownership of it when you hit enter or send. Who you send it to, where you post it, they take ownership of that information whether you like it or not. Mark Cuban
itself strength
One of the things that launched the strength in biotech is when the pharmaceutical industry itself got a little slow. Louis Navellier
itself lend setting troubled
With 'Holes' I was troubled that there weren't very many female characters. I tried to put them in where I could. But the setting didn't lend itself to girls. Louis Sachar
itself outcome risk shows
The outcome itself shows it was an unreasonable risk. Jeff Justice
itself legitimacy thus
Where 'Paranormal Activity' really comes into its own is its rhetoric of legitimacy - how it uses itself to authenticate itself, and thus furthers the pretence of being real. Stephen Graham Jones
itself left microsoft
What's left under MSN -- MSNBC? Microsoft just divested itself of that, too. Matt Rosoff
itself plan rules
The plan itself is still being drafted. We're working with HUD on rules and regulations. Pete Smith
itself ok stopped stuff sundance
There is nothing I can do about this stuff and I am pretty well ok with the fact that I think Sundance is not going to be stopped by it, because he Festival is itself now, and doesn't need me out there to talk about it like I did years ago. Robert Redford
itself knew music
The music sold itself before anybody knew who I was. Enya
itself knocking narrative starts
When the narrative itself starts knocking on the glassed-in box that was your prescription for how you were going to write this novel... you have to listen to it. Jim Crace
levels might fields
I just feel compelled to continue to be transparent. It just really levels the playing field and eradicates the shame that I have, or that one might have, about being human. So I'm going to just keep going. Alanis Morissette
levels harmony discord
So what is discord at one level of your being is harmony at another level. Alan Watts
level next worthwhile
We want to see what's out there and is it worthwhile to take anything to the next level of funding. James Allen
levels teammate comfort
Keep being aggressive, that's what my teammates and my coaches ask me to do. If I see things are going well, I know there's more of a comfort level for me to continue to do that. Chris Copeland
levels ordinary different
Spirituality doesn’t exist on another level different from ordinary life. Chogyam Trungpa
levels hierarchy size
The truly privileged theories are not the ones referring to any particular scale of size or complexity, nor the ones situated at any particular level of the predictive hierarchy, but the ones that contain the deepest explanations. David Deutsch
levels embarrassment lows
I've generally got low levels of embarrassment. Caitlin Moran
level lost love paul saw truth
When I saw Paul Scofield do 'Love's Labor's Lost at Stratford,' that's when I saw the potential of the level of truth that could go on up there on a stage. I said, 'This is what I want to do.' Michael Moriarty
level product schedule struggled until
We struggled at times, but most of it was because of our schedule. It was more the product of our schedule than how we were playing. We really didn't play at the level we could until New York. Jim Boeheim
message ok orleans running send
We want to send the message that New Orleans is up and running and it's OK to come back. Bill Taylor
message send sharp strong suspension talks temporary
We want to send a very strong and sharp message to the Palestinians, and the temporary suspension of talks is that message. Mark Regev
messages willing commanders
I am more willing to come out when I get my message from my commander. David Koresh
messages beats audience
If the beat gets to the audience, and the message touches them, you've got a hit. Casey Kasem
messages beats music-is
But otherwise, music is about a beat and a message. Casey Kasem
messages dramatic persuasive
We can be dramatic, even theatrical; we can be persuasive; but the message we are telling must be true. Edwin Land
message peace people understand
We want people to understand our message is one of peace and not one of hate. Megan Challender
message putting respond responsibility rests seemed
Ultimately, the responsibility rests with the drivers, and they seemed to respond to the message we were putting out. Mark Phelan
messages rich certain
Music in itself carries a whole set of messages which are very, very rich and complex, and the words either serve to exclude certain ones or point up certain others. Brian Eno
resides
As long as it resides in my lake, I have to keep the lakeshore cordoned off, Janice Hahn
wonderful hypothetical
Now everything is wonderful and hazardous and nothing's hypothetical. Alan Moore
wonderful scientist interest
I'm in this wonderful position where I can do what interests me. And whatever comes along that interests me, I do. The rest of the time I bother scientists about communicating. Alan Alda
wonder-love two people
Each of us has been designed for one of two immortal functions, as either a storyteller or as a cross-legged listener to tales of wonder, love, and daring. When we cease to tell or listen, then we no longer exist as a people. Bryce Courtenay
wonder ifs
And it's the wonders I'm after, even if I have to bleed for them. Catherynne M. Valente
wonderful used many-friends
It's wonderful to meet so many friends that I didn't used to like. Casey Stengel
wonderful cheeky
Don't let them get you down. Be cheeky. And wild. And wonderful. Astrid Lindgren
wonderful
When or if answers are found, you can be assured those answers will lead to more questions. Is the troubling or wonderful? It depends on your view of your place in nature, your place among the stars; I suppose. Bill Nye
wonder silver chairs
You see, Aslan didn't tell Pole what would happen. He only told her what to do. That fellow will be the death of us once he's up, I shouldn't wonder. But that doesn't let us off following the signs. - The Silver Chair C. S. Lewis
wonderful
Every time I read Erin Belieu work I'm pierced in that wonderful way poetry can. Cheryl Strayed