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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
against arrange highest lower price sale timing weigh
We want the highest price possible. You have to weigh that against some risk: the timing of the sale and how long it could take to arrange financing. So sometimes it does make sense to take a lower price. D. Miller
against bodies offense progress test
We want to test ourselves, see the progress we've made against bodies other than the UB offense and get a feel for where we are, what we need to do, and take it into the season. Tom Jones
against associate bobby discuss information jimmy man trial
There was a man who was an associate of jimmy Hoffa, who testified against Hoffa in his trial down in Tennessee. We had information from him that he and Hoffa did, in fact, discuss the planning of an assassination conspiracy against Bobby Kennedy. Louis Stokes
against both brazil match sides
The match against Brazil was football at its best. Both sides had opportunities to win the game. Michel Patini
against extremism prejudice pretend tackle
The way to tackle Muslimphobia is to tackle prejudice against Muslims. What it is not is to pretend that Islamist extremism does not exist. Maajid Nawaz
against concerned good helena quick
The one thing you're always concerned with against Helena is transition. They're quick at it, they're good at it, so you have to be good at it. John LaFontaine
against champion fight key stand team
The other team is always going to make a run. The key to being a heavyweight champion is to fight back and stand up against the punches. Orlando Early
against coin continue deserve player side terrific win
The other side of the coin is that we had a terrific win against Adelaide, and every player deserve to continue on. So it is pretty tight. Chris Connolly
against comparison easy fourth improving last note positive results year
The positive thing to note is that they actually had improving results as the year went on. But they were going against a very easy comparison -- they were down 3% in last year's fourth quarter. Benj Steinman
deep-thought disease saws
I am not superstitious, but the first time I saw this medal, bearing the venerated likeness of John Calvin, I kissed it, imagining that no one saw the action. I was very greatly surprised when I received this magnificent present, which shall be passed round for your inspection. On the one side is John Calvin with his visage worn by disease and deep thought, and on the other side is a verse fully applicable to him: 'He endured, as seeing Him who is invisible. Charles Spurgeon
deep-water water knowing-god
You will never know God's strength until He has supported you in deep waters. Charles Spurgeon
deeper determines experience god greatest personally power push quality quite talk teacher walk within
How well I walk my talk, and not talk my talk, determines the quality of my engagement, of all my experience with what is quite personally my God. I'm my greatest teacher, and within me, I have the power to push myself deeper and higher. Lorraine Toussaint
deep proves
We've always been deep on the bench, ... and it just proves that we can play with any team. Tim Palmer
deep shadow
Where there is much light, the shadow is deep Johann Wolfgang von Goethe
deep dirt parking ruts train walk welcome
When you walk off the train from New York, you see this dirt parking lot with deep ruts and tractor-trailers with graffiti on them. Welcome to New Brunswick. Bill Bray
deeper type understanding
It's so important as a creative person to go out and look for things. Go to galleries, talk to people, read books. Yes, you can just type something into Google, but if you read and interact, you'll have a deeper understanding of the world. Nicola Formichetti
deeper work
There is nothing deeper than to work for a year with the same artist. Hans-Ulrich Obrist
deep man mystery object retain simple somehow
I think those who object to my characterizing man as simple want somehow to retain a deep mystery at his core. Herbert A. Simon
illinois people house
What success I achieved in the theatre is due to the fact that I have always worked just as hard when there were ten people in the house as when there were thousands. Just as hard in Springfield, Illinois as on Broadway. Bill Robinson
illinois issues use
Illinois Senator Paul Simon, once said "The test for a Supreme Court nominee is not where he stands on any one specific issue. The test is this: Will you use your power on the court to restrict freedom or expand it"? Dick Durbin
illinois black population
Illinois has less than a 12 percent black population and I won with 55 percent of the vote. Carol Moseley Braun
illinois nominations republican
I accept the Republican nomination for the U.S. Senate, to represent the State of Illinois. Alan Keyes
illinois needs mets
I am committed to working with Speaker Hastert and the other members of the Illinois congressional delegation to do all that I can to ensure that Illinois' funding needs are adequately met. Bill Lipinski
illinois paying payment providers state stretch
What he's going to do I think is stretch out the payment cycle. What he's going to do is essentially make the providers of the state of Illinois pay for it by paying them more re-imbursements and more slowly. Steve Rauschenberger
illinois states middle
I grew up in Danville, Illinois, right in the middle of the state. Dick Van Dyke
illinois people usual
To the people of Illinois let me say this. Business as usual IS OVER. Bruce Rauner
illinois style
To us, it's novel. In Illinois (where we are from), this would not sell. They don't like this style. Nancy Barr
marquee push road seed win
This would be our marquee win, a road win at Texas. I think that could push us up one seed or two. Kevin Bookout
marquee survive
The marquee is going to survive August, ... And it is going to survive me. Rocco Landesman
marquee others raising spend talking time upgrade urge
We spend a lot of time talking to our tournaments about the need to upgrade what they do. Yet we're the marquee event, and if we're going to urge others to keep raising the standard, we have to show them what it is. Bob Combs
marquee
I've been to Marquee in New York. And this is the upscale of the Marquee in New York. Kevin Federline
marquee middle miss player unless
If you're up top, you get a marquee player through about 10 or 11. If you're in the middle of the pack, you'll miss out on that unless you go up. A.J. Smith
played taken
We've already done that. The two quarterbacks we have, Vincent hasn't played before and Gill played JC. We've taken out as much as we can. Hal Mumme
played stopped ways
We stopped doing all the little things that we did earlier. We reverted back to some of our old ways and played with not a lot of intensity. Mike Pomerenke
played stood
We stood up to the challenge. We played very well. We did not play well enough to win. Dave Odom
played
We started a little slow, but we hadn't played any. Scooter Dunn
played since team time
We were a whole different team since the first time we played them. Indy Uhlenhopp
played teams
'Justified' is one of the greatest teams I've ever played for. It's just awesome. Neal McDonough
played
When we weren't in the box, I thought we played pretty well. Jeff Halpern
played proud starting
We're starting to come together. We played as a team, and I was very proud of them tonight. Travis Paquet
played prepared time
We're more prepared for it than the first time we played them. Jeff Perreault
sincere substitutes ardent
There is no substitute for thoroughgoing, ardent, and sincere earnestness. Charles Dickens
since stimulated
We started giving presentations at practitioner conferences in 1986, and since then all of our derivatives research has been stimulated by contact with practitioners. John Hull
sincere loses
How can we lose when we're so sincere? Charles M. Schulz
since
I've always been interested in singing, and I've always been singing and dancing since I was little. Lindsay Lohan
since
What they have done is insufficient. It's now two years since the decision. Jonathan Todd
since uncharted
We're in uncharted territory. We haven't experienced something like this since the 1980's. John Felmy
since
You know, I didn't get to go to university because I've been acting since I was a kid. Isla Fisher
since time
I say to my mother all the time, 'You're the child.' And she says, 'Yeah, you're the mother.' I've been that way with her since I was 11. Kristy McNichol
since
Since I can't write the greatest American novel, I'm going to write the longest American novel. Thomas Steinbeck
southern desire pieces
The Northern onslaught upon slavery was no more than a piece of specious humbug designed to conceal its desire for economic control of the Southern states. Charles Dickens
southern said southerner
A true Southerner will never say in 2-3 words what can better be said in 10-12. Charles Kuralt
southern election certain
The secession of the Southern States, individually or in the aggregate, was the certain consequence of Mr. Lincoln's election. Belle Boyd
southern comfort world
I can't see this world unless I go/ outside my southern comfort zone. Brad Paisley
southern heritage dialect
I'm most comfortable with the Southern dialects, really. It's easy, for example, for me to do Irish because we've got Irish heritage where I come from. Brad Pitt
southern gentleman southern-gentleman
I'm a southern gentleman. Jamie Foxx
southern flying towns
Been on what I call my Flying Saucer Tour--appearing in small Southern towns--in front of handfuls of hillbillies. Bill Hicks
southern
We really have no idea what is going on now in southern China. Guan Yi
southern
Many, many of them are from southern Louisiana. Samantha Bingham
sweet smell long
So long as lust, whether of the world or flesh, smells sweet in our nostrils, so long we are loathsome to God. Charles Caleb Colton
sweet flower book
I have somewhere seen it observed that we should make the same use of a book that the bee does of a flower: she steals sweets from it, but does not injure it. Charles Caleb Colton
sweet flower book
Others, again, give us the mere carcass of another man’s thoughts, but deprived of all their life and spirit, and this is to add murder to robbery. I have somewhere seen it observed, that we should make the same use of a book, as a bee does of a flower; she steals sweets from it, but does not injure it; and those sweets she herself improves and concocts into honey. But most plagiarists, like the drone, have neither taste to select, nor industry to acquire, nor skill to improve, but impudently pilfer the honey ready prepared from the hive. Charles Caleb Colton
sweet nature morning
The rich, sweet smell of the hayricks rose to his chamber window; the hundred perfumes of the little flower-garden beneath scented the air around; the deep-green meadows shone in the morning dew that glistened on every leaf as it trembled in the gentle air: and the birds sang as if every sparkling drop were a fountain of inspiration to them. Charles Dickens
sweet men way
Man loves his own ruin. The cup is so sweet that though he knows it will poison him, yet he must drink it. And the harlot is so fair, that though he understands that her ways lead down to hell, yet like a bullock he follows to the slaughter till the dart goes through his liver. Man is fascinated and bewitched by sin. Charles Spurgeon
sweet light ministers
Light physical is said by Solomon to be sweet, but gospel light is infinitely more precious, for it reveals eternal things, and ministers to our immortal natures. Charles Spurgeon
sweet jesus father
It is sweet to remember that the exaltation of Christ in heaven is a representative exaltation. He is exalted at the Father's right hand, and though as Jehovah He had eminent glories, in which finite creatures cannot share, yet as the Mediator, the honours which Jesus wears in heaven are the heritage of all the saints. It is delightful to reflect how close is Christ's union with His people. We are actually one with Him; we are members of His body; and His exaltation is our exaltation. Charles Spurgeon
sweet memories blessed
Good thoughts are blessed guests, and should be heartily welcomed, well fed, and much sought after. Like rose leaves, they give out a sweet smell if laid up in the jar of memory. Charles Spurgeon
sweet joy sorrow
There is a sweet joy that comes to us through sorrow. Charles Spurgeon
teams
The other teams have left, and they're still not really back. We haven't left, and we're not going anywhere. Walter Leger
teams
We've already made the decision. Most teams put five, but we're going to put six. Alain Vigneault
teams three
When the three of us are on, we're really tough. There are not a lot of teams that can keep up with us when we play like that. Paul Davies
teams trying
We're just still searching, just trying to find out what teams are the best. Steve Rodecap
teams
Most teams that you have, they have one or two go-to guys. They've got a go-to team. Bernie Bickerstaff
teams top
Most of the teams at the top just didn't give up as much ground. Matthew Faltys
teams
When we started out as freshmen, we were ok, but there were other teams out there who were a lot better than us. Tyler Mitchell
teams travel
Many of them play on the same travel teams and know each other well. Marissa Chovanec
teams
SEC teams are going to make runs. That just happens. It's part of the game, man. Eric Ferguson
wins
For some reason, we play better on the road. Some of our wins are ugly, but we don't care. E. P. Thompson
wins
In 2014, we have some new activities and new order wins in the non-automotive space. Baba Kalyani
wins worry
You know, it's going to happen. I'm not going to worry too much. We're getting wins and right now we're in first place and that's all that matters. Gino Guyer
wins
We got to 10 wins and I still think there are things we need to tighten up. Mike Vrabel
wins
I was nervous, ... And you think about Utah, and all the wins they've had, it makes you more nervous. But I did what I had to do. Aaron Brown
wins
That's good. Now, we've just got to get him the wins that count. David Bowens
wins worry
I just worry about the wins right now. Brian Gionta
wins
It was important. It's one of the wins we need to try and make districts. Angelo Johnson
wins
I think about getting the wins to put us atop of the conference. That overshadows everything else. Mark Walters