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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
chemical
We have no such weapons at all, no chemical weapons, no biological weapons. Mohammed Aldouri
chemicals chosen companies cost costs declining driving due fall flat impact industries logistics measure metric multiple operate percent performance power prices pricing primary ratio rising sales saw strong though top using
While many companies use multiple logistics cost measures, the primary metric chosen can have a significant impact on how logistics cost performance is viewed. For example, those companies using logistics costs as a percent of sales as their primary measure and who operate in industries such as chemicals and other commodities saw that cost ratio fall in 2005 due to strong upward pricing power that impacted the top line, even though logistics costs also rose. Other industries had rising logistics costs with flat or declining prices for their products, driving up logistics costs as a percent of sales. Dan Gilmore
chemical exposure highest hurricane industry lose union
Union Pacific's exposure to the chemical industry is the highest of all the rails, so it had the most to lose from Hurricane Rita. Peter Smith
chemical compound extending range reactions success widely
This success led my theoretical group to the chemical reactivity theory, extending more and more widely the range of compound and reactions that were discussed. Kenichi Fukui
chemical distinct information provide reacting reactions role served shape
This simple idea served to provide information on the geometrical shape of reacting molecules, and I was able to make the role of the frontier orbitals in chemical reactions more distinct through visualization, by drawing their diagrams. Kenichi Fukui
chemical easily passes purely split
As is known, the sugar molecule as it passes through lactic acid can easily be split by purely chemical means. Eduard Buchner
chemicals cures
Thoughts are chemical. They can either kill us or cure us. Bernie Siegel
chemical finding full influence likelihood might molecules organisms since turn useful
Since there are so many different environments in the soil, the likelihood of finding different organisms and different chemistries is high. The world is full of microorganisms that have learned, chemically, how to get along, how to communicate with, how to influence other animals. It might turn out that they're making chemical molecules that turn out to be useful to people. Robert Goodman
chemical dangerous food further human identify move necessary per premature stores studies taking ultimate
We really don't know if human consumption of that chemical is dangerous per se, so it's premature to say. We don't move on taking it out of the food stores yet. Further studies are necessary to identify the ultimate outcomes. Andrew Olaharski
clearly economy employment fed influenced next potential reflection report surprise
The potential is that there could have been a surprise that could have influenced the Fed next Tuesday, and clearly that hasn't happened. But employment is a lagging indicator. So the report is not a reflection of where the economy is going, but where it's been. Douglas Altabef
clearly position remains stated
The position remains as we have clearly stated it on many occasions. Peter Varney
clearly internet pleased
We are pleased with the decisions. It clearly established the constitutionality of the Internet Registry Act. David Wald
clearly consensus dollar next risks short upside
There are clearly upside risks around the consensus expectations for non-farm payrolls. As such, we would not be short the U.S. dollar over the next 24 hours. John Kyriakopoulos
clearly identify lead problems stated sudden theme
There are clearly stated problems that we have to identify and have to uncover. The overlying theme is things that would lead to sudden incapacitation, Dave Roberts
clearly core data debate decision fed help inflation market numbers raising remains resolve stop until whether
We're in a market that is clearly in a little short-term decision box. It's the debate whether core inflation remains low, which allows the Fed to stop raising rates, or whether core inflation is not able to be contained. We'll get a progression of data and numbers that will help resolve this somewhat, but until then, we're in the box. Rod Smyth
clearly fort longer meant planned recognize regret sincerely spent
We spent longer than we had planned in Fort Lauderdale, which meant that the itinerary has had to be changed, and we do regret that sincerely and clearly we do recognize there's been a lot of disruption. Carol Marlow
clearly content freedom golf good hit life thinking
If you're thinking clearly and are content about where your life is - to where you can just think about the present, think about the now - that's what you need to do to hit good golf shots. I know there are a lot of distractions, but when you're thinking clearly, you're more free. You've got to have that freedom on the golf course. Lucas Black
clearly happier identical invent liberated national pretending rather spanish
I'm happier not pretending I know anything about El Cid in Spain. He's a Spanish national hero. I'd rather invent a character inspired by him but clearly not identical to him. And then I feel liberated creatively. Guy Gavriel Kay
extremely fulfilling helped kids laid learning nine original parents people program proud
We started the program nine years ago with kids that were just learning to play hockey, so this is a fulfilling day for me and a lot of original parents who helped for the organization. We're extremely proud of these kids, particularly, and for all the people who laid the groundwork. Kevin Quinn
extremely job kept man worked
We started out in a match-up zone. But we've worked and worked and worked on our man defense, and we did an outstanding job with it after the first quarter. I think we got Murdock extremely frustrated, and we kept (Marietta's guards) pretty contained. Robbie Stancil
extremely finishing game good heavy last minutes paid price weekend
Where our finishing was very, very good last weekend it let us down tonight. We really should have put the game away in the first 90 minutes and we haven't done that and have paid a heavy price for it. We are extremely disappointed. Sam Allardyce
extremely planet
I'm just extremely excited to explore the planet that we're living on. Nick Woodman
extremely fun great people plays quick support team
We want people to come support us, and I think they're going to see a great game. They are an extremely quick team that plays hard. It should be fun to watch. Don Flanagan
extremely focused gasoline markets product remain weak weakness
US product markets remain extremely weak at present, with most of that weakness focused in gasoline markets. Kevin Norrish
extremely
We're doing extremely well ... it's so exciting. Jan Nash
extremely glad mistakes
We're extremely glad to get the win, ... but we're still making too many mistakes. Jim Sweeney
extremely governor piece property rights work
We're extremely disappointed that the governor vetoed an important property rights piece of legislation, and we'll work to override the veto. Scott Shockley
facts may opinion
You may alter an opinion, but you cannot alter a # fact . Charles Spurgeon
factor growth leading robert since success thank valuable vision
We want to thank Robert for his valuable contribution to the Company's development and growth since its inception, ... His entrepreneurial vision has been a leading factor in our success to date. Glenn Parker
facts embarrassing theft
[A] great embarrassing fact… haunts all attempts to represent the market as the highest form of human freedom: that historically, impersonal, commercial markets originate in theft. David Graeber
facts economic globalization
Globalization is a fact of economic life Carlos Salinas de Gortari
facts sacred comment
Comment is free but facts are sacred. C. P. Scott
facts republican celebrate
Well, I'm celebrating the fact that Republicans are doing better with women. Cathy McMorris Rodgers
fact feels funny might mug people twice wake
I wake up every day and look at my own ugly mug in the mirror and don't think twice about it. The fact that other people might want to look at me still feels funny. It's flattering, but funny. Luke Bracey
fact positives truth
The positives are closure. The fact is we participated with an ineligible player. That's the truth. You can't sugar-coat that. Gene Smith
fact last proud
We are proud of the fact that we surpassed last year's donation. Robert Fraser
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
lethal people sort
They thought someone was going around injecting people with some sort of lethal medication. Frank Minyard
lethal playing since third together
Those two have been playing together since third grade. They are a lethal one-two punch. They set each other up well. Kurt Hempen
lethal question risk
There's no question with this kind of essentially lethal risk that there is going to have to be some kind of risk-management program. Robert Temple
lethal weapons
These weapons were extraordinarily potent. Some of them were actually engineered, genetically, to become more lethal than the strains in nature, Jonathan Tucker
lethal nice tall
It was nice to see him out there. He's big, strong, tall and fast. That's a lethal combination. Charlie Frye
producers belle protective
On Belle de Jour, the producer was very protective. It was very hard for me. Catherine Deneuve
producers
There are certainly producers I hang with and directors I hang with and actors I hang with. Michael Keaton
producers automobile vehicle
You cannot buy a bad automobile any more from any producer. We have to do more products not because we're looking at a particular segment, but because it's a great vehicle. Bob Lutz
produce sought tasted
I always sought out organic produce because to me it always tasted better; the quality was better - if you got it fresh. Nell Newman
produce production
We're manning up production as much as we can, ... We can only produce so many. Richard Thomas
produce surprised
We're going to produce some runs, and I would be surprised if we didn't. Max Bukovac
produce six steel stronger
With nanotechnology, you can produce steel that's 100 times stronger but six times lighter. Jim Thomas
produces
It's the dualistic ways of looking at things that produces the evil. Robert M. Pirsig
producers
The producers want us to sell, sell, sell. That's my little joke. That's what we do by day; by night, we're artists. Mike Nichols
repeats i-can
Repeat after me: 'I am doing the best that I can.' Debra Messing
repeat sustained talk worry
One can always hope, but I worry this will be a repeat of that experience. After the 1960 riots, there was a lot of talk and a lot of commissions, but there was no real sustained action. Alan Curtis
repeat run
I can't repeat that in the paper. You've got to let him know you can't let him run around like that. I just told him, we play them one more time. Chris Neil
repeated
We've been there over a week, and we've made repeated requests. Ron Redmond
repeat wish
I wish I could repeat it a little more often. Darren Clarke
repeat
I will repeat that, again, he's been disciplined. Jeff Bower
repeat tough
It doesn't get any easier. It will be tough to repeat what we did today. Judd Anderson
repeat type waste
Don't even try to type him. It's a waste of time. He'll never repeat tendencies. Zach Thomas
repeat win
The way things are going here, we could repeat the 1996 result. Only this time, we should win the trophy. Milan Baros
states secretary
I loved what I did. I could've been secretary of state for ever. Madeleine Albright
states evident secretary
I loved being Secretary of State, that's probably evident to everyone who watched me. Madeleine Albright
states barometer interest
...interest is the barometer of the state... David Hume
states hyperbole constant
I live in a constant state of hyperbole. Eden Sher
states senators productive
I was very productive as a senator for my state. Carol Moseley Braun
state
We wrestled better than we did in the first. We got after the guys, and they wanted to get to the state final. Clifford Garnto
state
to play in the state in which they're franchised. Paul Tagliabue
state
We're realists. We know we're in a state where the Legislature is anti-choice. Susan Hill
state systems whether
When the state inspectors look at us, they will see that the systems are in place. You have to have a system whether you have one person or 100. Al Mollozzi
tape research labs
I started in a research lab for TV cameras, then I worked at a tape duplication facility. That was the first introduction for me to recorded music and hi-fi. Alan Parsons
tape golden eras
A cool & diversified version of a mix tape. The BreakBeat Poets is a thorough and complete summation of Golden Era writers who continue to build the scene of literary and performance poetry. Chance The Rapper
tape cameras eric
I'd just like to know what a cop WOULD have to do to get indicted - and what good are cop cameras since Eric Garner IS on tape? Bill Maher
tape watch
Watch the tape throughout, and you'll see him doing things like that. Josh Childress
tapes watching work
Watching those tapes told me I've still got a lot of work to do, Derrick Brooks
tape faces graves
Those [Watergate] tapes are going to take me to my grave with a huge smile on my face.. Ben Bradlee
tape degrees moments
I used to be so hard on myself. So hard on myself. Just my own worst critic to the nth degree. Absolutely undermining my confidence in every moment. Bad tape in my head all the time. Bellamy Young
tape
When I look at myself on tape I can see that, but I just didn't make the adjustments at the time. Alfonso Soriano
tape realizing invisible
There is probably more invisible tape out there than we realize. Demetri Martin
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
tests firsts beats
Everything I make as a producer, I visualize it as a DJ first. And all those beats, I test them as a DJ. David Guetta
tests failing explanation
Where we have good, testable explanations, they then have to be tested, and we drop the ones that fail the tests. David Deutsch
tests majority failing
The overwhelming majority of theories are rejected because they contain bad explanations, not because they fail experimental tests. David Deutsch
tests poultry clients
I would expect an extremely high percentage of the chickens would test positive. Our poultry industry clients wouldn't like that. Bryan Shelton
tests firsts calling
The test of a first-rate work, and a test of your sincerity in calling it a first-rate work, is that you finish it. Arnold Bennett
tests faces indifference
The test of an invention is the power of an inventor to push it through in the face of staunch-not opposition, but indifference-in society. Edwin Land
tests way facts
Evolution is a theory, and it's a theory that you can test. We've tested evolution in many ways. You can't present good evidence that says evolution is not a fact. Bill Nye
tests rings universe
The universe rings true whenever you fairly test it. C. S. Lewis
tests
We meet all life's greatest tests alone. Agnes Macphail
toward wants
We're just working toward that now. Everyone wants to be in the same place at the end. Ryan Getzlaf
toward
For more than eight decades, Washington has been my hometown. My whole orientation is toward this place. Katharine Graham
toward victims violent
I think 'Dirty Harry' was probably sensitive toward the victims of violent crime. Clint Eastwood
toward
We still have a long way to go and we're still working toward that. Maurice Cheeks
towards
We are moving towards a new form of collective intelligence. Jane McGonigal
towards
I am very reactive towards everything. There are some who don't react at all, they absorb everything quietly, while I'd go all out and show my expressions. This is not part of some tamasha I do; I do it because it's part of my personality. To each his own. Preity Zinta
toward
I think a policy of isolationism toward Cuba is misplaced and hasn't worked. Rand Paul
toward vast within
One speck within vast star-space lyingAwoke, arose, resumed its clothing,And crawled another day toward dying. William Benet
toward western
It is going more and more toward the Western part of the world. Joseph Domenech