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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
biggest last mistakes three won
We've won our last three that way. We'll take 26 more like that as long we win. We never get discourage. We just play through our mistakes and that's the biggest difference. Al Harrington
biggest butter cake care eat favorite favors home love mad mom name siblings sweet time
I have the biggest sweet tooth! You name it, I will eat it. My all-time favorite is my mother's butter cake. Every time I go home, my mom will already have the cake made because I love it so much. This makes my siblings mad because they think she favors me. I don't care because she probably does! Michael Strahan
biggest compete hungry products showcase support
The other thing is, I know how competitively hungry they are. They're not here just to be here. They're here to compete hard, showcase their products and support their teams. And they're going to do it on the biggest stage. Brian France
biggest capital corporate funding high hybrid investors market potential since yield
The potential of the hybrid capital market is enormous. As issuers and investors become more comfortable with these securities, they could become one of the biggest corporate funding innovations since high yield bonds. Michael Klein
biggest performance prove surprise
The post-Fed performance of the S&P 500 could prove to be the biggest surprise of 2006. Francois Trahan
biggest concern easier elderly fearful near paper people perception quite
The perception of some of the elderly is that it's electronic, and (they) don't want to get near it, but quite frankly, it's easier to use than the paper ballots. My biggest concern is elderly people that are too fearful to even try. Don Briel
biggest bring champions city classic community continue continues financial foundation golf great greater heritage history join kansas local major means names played pleased pride three tour tournament
We are pleased to join with three other great local companies, the Pride of Kansas City Foundation and the PGA TOUR to continue to bring the Champions Tour to Kansas City. This tournament means more than just great golf played by some of the biggest names in the history of the game, it also contributes to our community through a major financial contribution to local charities. Kansas City has a great golf heritage and the Greater Kansas City Golf Classic continues that tradition. Len Lauer
biggest brush cigarette determine exact fires offender people
We are averaging as many as 15 brush fires a week. We can't always determine the exact cause, but the biggest offender is people flicking cigarette butts out of their cars. Ray Yeakley
biggest current expansion gases greenhouse losing moving risk solving
We are at risk of losing some manufacturing, but the biggest risk is we won't get any expansion of current manufacturing. You're not solving the problem. You're just moving the greenhouse gases to another location. Dorothy Rothrock
complex difficult order presence require time
We started this for the right reasons, ... We're on the right track. It is a very, very difficult and complex track. But in order to get there, it is going to require the presence of Americans for probably a long time to come. You'll see us downsize, I hope, immediately. But it is still going require us to be there for a while to come. Saxby Chambliss
complex due front locations ubiquitous
Clearly-drawn front lines have become a thing of the past due to complex locations with ubiquitous enemy threats. Niki Tsongas
complexes talking three
When you take those three complexes alone, you're talking about hundreds of units. Bob Lambert
complex far impose life structures suspicious tendency writers
It's worth being suspicious of writers - or anyone! - who does that myth-making thing. There's always a tendency to retrospectively impose structures on a life. Life as it's lived has a far more complex shape. Guy Gavriel Kay
complex familiar games good players team though whether won year
Whether they had the new players or not, they're still a team we're not familiar with. They're a complex team and even though they haven't won many games this year they still have some good qualities, especially with the new players they've added. Amado Guevara
complex document gives insight movements piano process quartet rare work
What this document gives us is rare insight into the imponderable process of decision-making by which this most complex of quartet movements is made over into a work for piano four-hands. Richard Kramer
complex
What's really complex about it is you're going to have to do allocations you've never had to do before. Mark Luscombe
complex engaging last
Working with celebrities has become, over the last decade, a lot more complex with so many more nonprofits engaging with celebrities. Darren Irby
complexity greater increased life sort sublime toward unfolding
If the process of life is about moving toward increased complexity and organization, a sort of sublime unfolding of greater and greater self-organizing systems, then we're actually doing pretty well. Jason Silva
core good group help host impossible meet officials support thank
We want to thank the officials organization. We get a really good group of core officials to help with the meet. It would be impossible to host the meet without the support that we have from the community. Scott Walkinshaw
core everybody interviews knows life
Interviews don't go to the core of my life. Everybody knows my life - it's an open book. Michael Moriarty
core definitely exams focus items sections
There are definitely items and sections of the core exams that focus on security, Robert Stewart
core despite industries manhattan publishing
There are core industries in Manhattan that are thriving, despite the recession, and publishing is one of them. Robert Freedman
core cost early energy increases jump limited longer mature pass power pricing rest saw seeing today whenever
We still see limited penetration into the rest of the economy. It's too early to say you're seeing pricing power to pass on the energy cost increases just because you saw just a jump in the core PPI number. The world has changed. In the old traditional world, whenever you had mature expansion, you had pricing power. Today with globalization, that's no longer the case. Anthony Chan
core divisions processes production
We want our divisions to concentrate on the automotive core processes - development, production and sales. Dieter Zetsche
core exercises work
I do a combo of running, weights, and core exercises and try to work out at least three times a week. Lisa Vidal
core dismiss diverse great music panic reflect single tried widespread
We've always tried to reflect people's diverse music collections. We don't want to dismiss our core in any way, but . . . as great as Widespread Panic has been to us and has been a really big part of what we've done, we can't have Widespread Panic every single year. Jonathan Mayers
core debate debated elsewhere environment game labor looking rules seattle treated whether
What we're looking at in Seattle is a debate over the rules of the game and how the environment and labor will be treated -- whether they will be debated elsewhere or whether they will become part of the core discussions about trade. Harley Shaiken
differences rome atheism
Sir Richard Steele has observed, that there is this difference between the Church of Rome and the Church of England: the one professes to be infallible, the other to be never in the wrong. Charles Caleb Colton
differences law grace
Relationship is the difference between grace and law. Charles Stanley
differences galaxy
Where-so-ever beings exist throughout all galaxies, it doesn't make any difference - you are all of them....and when they come into being, that's you coming into being. Alan Watts
differences anxiety amount
No amount of anxiety makes any difference to anything that is going to happen. Alan Watts
differences numbers life-and-death
A live body and a dead body contain the same number of particles. Structurally, there's no discernible difference. Life and death are unquantifiable abstracts. Why should I be concerned? Alan Moore
differences empowerment want
You can’t buy that kind of empowerment. To just know that as far as you are aware, you have not got a price; that there is not an amount of money large enough to make you compromise even a tiny bit of principle that, as it turned out, would make no practical difference anyway. I’d advise everyone to do it, otherwise you’re going to end up mastered by money and that’s not a thing you want ruling your life. Alan Moore
differences leisure tvs
The difference between film and TV is the pace. You don't have the leisure of time in television. Alan Ball
differences climbing perspective
The difference between a mountain and a molehill is your perspective. Al Neuharth
differences done jersey
This is a difference between being a governor and being in a legislature. Because when something doesn't work in New Jersey, they look at me, say: "Why didn't it get done? Why didn't you do it?" You have to be responsible and accountable. Chris Christie
directed movies
The first two movies I directed failed, when I was 21 and 23, and that was the greatest thing that could have happened. M. Night Shyamalan
directed england found historic historical letters lord purchase showing stanley travel
We found historic letters showing that Lord Stanley directed his aid-de-camp to travel to England to purchase the Cup. That was an interesting historical find. W. S. Gilbert
directed finding individual message reminding voters
We know he has done a very retail-oriented campaign, going right to individual voters and surgically finding those who will vote and vote for him. His message is directed at reminding voters what he has done for them. Bob Stein
directed practical toward
She is so smart, it's scary. She's very much a theoretician, but it's always directed toward what's practical and possible. James Chessen
directed fact filmmakers films good men nominated women year
The fact that men and women are nominated this year in films that women have directed is good for women filmmakers generally, Catherine Hardwicke
directed influenced
The real blackmail is what Chirac has done. I am very disappointed that Chirac has influenced and directed the meeting. Jacques Chirac
directed
I've directed a couple of times in the theater, but I wouldn't make a habit of it because it's too consuming. Brian Cox
directed feature tim
I'm being photographed, worrying about my hair - and yet here I am, I've directed a feature film, why do I care about the way I look? Who cares? Does Tim Burton care? Does Joel Coen? Nicole Holofcener
directed ends form inside towards
Form as a goal always ends in formalism. For this striving is directed not towards an inside, but towards an outside. But only a living inside has a living outside. Ludwig Mies van der Rohe
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
less looking toward
We are looking less favorably toward 2016 bidding at this moment, Peter Ueberroth
less mean point push start sure year
We are at the point of the year where if you push him back, it could mean one less start at the end of the year. We need to make sure that he can pitch. If we do push him back, we want to make sure we have the matchups we need at the end of the season. Mike Scioscia
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
measures ourselves safety satisfied security
We have satisfied ourselves that appropriate safety and security measures will be in place. David Morgan
measures preventive un war
I am against preventive war because it means measures by the UN against us. Moshe Sharett
measures principal protect quite security
I'm insisting, quite unapologetically, on the need to have these appropriate security measures in place to protect the voters, which is my principal charge. Kevin Shelley
measures realize required steps
Extraordinary measures were required and I realize that not all of these steps were popular. Tom McCall
measures network onto people procedures security supposed
We used sophisticated security procedures and measures to make sure only people who are supposed to be on the network can get onto the network. Michael Clarke
measures rise stop
Kenyans should rise and stop this draconian measures by a dictatorship government. Raila Odinga
measures online security similar
There are similar security measures to those of online banking. John Proctor
measures
It'd be that much more if we didn't have some of the conservation measures we have here, Thomas Flynn
measures safety
We have a lot of safety measures in place already, so I feel pretty comfortable with those, Chris Gibson
population republican goodness
Goodness knows the Republican electorate is a pretty narrow slice of the population. David Price
population conservation policy
You don't have a conservation policy unless you have a population policy. David R. Brower
population potential proportion social
The potential for social unrest, social instability is pretty significant. You have a very substantial proportion of your population that has been undereducated, malnourished, marginalized, is disaffected, not able to go to school. John Williamson
population potential proportion social
The potential for social unrest, social instability is pretty significant, ... You have a very substantial proportion of your population that has been undereducated, malnourished, marginalized, is disaffected, not able to go to school. John Williamson
population climate problem
I've always been opposed to population control. In climate terms, population is not the biggest problem going forward. Bill McKibben
population
The population is healthy, but it's not like we've got a lot of them. Kelly Wood
population rate
The population is growing, the unemployment rate is dropping. It's a combination of those two factors. Charlie Roberts
population form educated
There is no better form of trade a developing nation can engage in than to sell services provided by an educated population. Brian Behlendorf
population should myth
There is a segment of the American population that has been excluded from the national myth, and that should be redressed. Edward Zwick
reading writing character
Mr. Pickwick took a seat and the paper, but instead of reading the latter, peeped over the top of it, and took a survey of the man of business, who was an elderly, pimply-faced, vegetable-diet sort of man, in a black coat, dark mixture trousers, and small black gaiters; a kind of being who seemed to be an essential part of the desk at which he was writing, and to have as much thought or sentiment. Charles Dickens
reading believe writing
I have nothing else to tell; unless, indeed, I were to confess that no one can ever believe this narrative, in the reading, more than I have believed it in the writing. Charles Dickens
reading writing style
Speech recognition is utterly crap for writing fiction. If you try reading a novel aloud you'll soon figure out why - written prose style is utterly unlike the spoken word. Charles Stross
reading years people
I hear people all the time say, well I read through the Bible last year. Well, so what? I'm all for reading through the Bible. But how much of that got on the inside, or did they just cover three more chapters today? I would never discredit reading the Scriptures, but it is important to meditate on it. Charles Stanley
reading age praying
It is a reading age, a preaching age, a working age, but it is not a praying age. Charles Spurgeon
reading believe water
To believe a thing is to see the cool crystal water sparkling in the cup. But to meditate on it is to drink of it. Reading gathers the clusters; contemplation squeezes forth their generous juice. Charles Spurgeon
reading light giving
Give yourself to reading.’... You need to read. Renounce as much as you will all light literature, but study as much as possible sound theological works, especially the Puritanic writers, and expositions of the Bible. Charles Spurgeon
reading writing impossible
...she felt about reading what some writers felt about writing: that it was impossible not to do it and that at this late stage of her life she had been chosen to read as others were chosen to write. Alan Bennett
reading long enough
The days weren't long enough for the reading she wanted to do. Alan Bennett
skills honey taste
Most plagiarists, like the drone, have neither taste to select, industry to acquire, nor skill to improve, but impudently pilfer the honey ready prepared, from the hive. Charles Caleb Colton
skills generations novelists
We're currently living with a generation of established novelists who are embarrassingly out of date with respect to social networking, internet skills, and so on. Charles Stross
skills perception taoism
But the transformation of consciousness undertaken in Taoism and Zen is more like the correction of faulty perception or the curing of a disease. It is not an acquisitive process of learning more and more facts or greater and greater skills, but rather an unlearning of wrong habits and opinions. As Lao-tzu said, "The scholar gains every day, but the Taoist loses every day. Alan Watts
skills age lucky
And the maestro surely wielded the chairman's baton with extraordinary skill. His stellar record suggests that the only right answer to the age-old question of whether it is better to be lucky or good may be: both. Alan Blinder
skills cards world
I don't know if this is an illusion but I would love to be able to take my card-throwing skills and be able to puncture a watermelon. Now I know I can take this question and say, "I would want to solve the economic problems in the world" - but I want to stick that card in that watermelon. Dave Franco
skills judging-yourself luck
Don't confuse luck with skill when judging others, and especially when judging yourself. Carl Icahn
skills class looks
You've got to look and pick your shots - and that's where your class and skill comes out. Billy Joe Saunders
skills mind soil
In the productions of the mind, as in those of the soil, the gifts of nature are excelled by industry and skill . . . Edward Gibbon
skills energy kind
Picasso is still influencing me. Of course, I haven't got that kind of energy, or skill. David Hockney
slightly
I am slightly shocked to have gone as far as I have. Steven Patrick Morrissey
slightly
'Kraken' is set in London and has a lot of London riffs, but I think it's more like slightly dreamlike, slightly abstract London. It's London as a kind of fantasy kingdom. China Mieville
slightly
I always feel like I've been slightly misunderstood. As a woman, you get judged for appearances or things like that I don't really care about. Lykke Li
slightly worried
I'm always slightly worried if I do a film and we're filming it in Luxembourg. I know it's going to go straight DVD. Michelle Gomez
slightly
I'm always for a weakened Conservative party, slightly or massively, John Godfrey
slightly spin
If anything it was a slightly more hawkish spin (than we were expecting). Rainer Guntermann
slightly somewhere venus wrong
I think we are all slightly down in the dumps after another loss. We may be in the wrong sign... Venus may be in the wrong juxtaposition with somewhere else. Ted Dexter
slightly style
Her style is gorgeous, provocative and ever so slightly deranged. Simon Doonan
slightly
I'm severely overrated. I'm just above a hack. That should be the name of my new DVD: 'Chris Rock: Slightly Above Hack'. Chris Rock
tasks advertising easy
It is an easy and vulgar thing to please the mob, and no very arduous task to astonish them. Charles Caleb Colton
tasks generations embrace
Every generation must recognize and embrace the task it is peculiarly designed by history and by providence to perform. Chinua Achebe
tasks reader
As a reader you have a task to do, you have something to do. You bring your experience to it. It's not all inherit in the poem. Edward Hirsch
tasks illusion principal
The principal task of friendship is to foster one`s friends` illusions. Arthur Schnitzler
tasks artistic solutions
That is the artistic task: To choose the best from these solutions. Arne Jacobsen
tasks may architecture
In addressing a task, one almost always has several possible options, sometimes only a few, and they may all be practical and functional. But they lack the aesthetic aspect that raises it to architecture. Arne Jacobsen
tasks
Unfortunately, I'm an engineer. I'm always thinking about, what's the task and how do I get it done? And some of my tasks are pretty broad, and pretty fuzzy, and pretty funky, but that's the way I think. Michael Porter
tasks problem states
The task of a writer is not to solve the problem but to state the problem correctly. Anton Chekhov
tasks holy knows
While it is good that we seek to know the Holy One, it is probably not so good to presume that we ever complete the task. Dietrich Bonhoeffer
types
We do need different types of propulsion to get to Mars. I wrote one of the first Ph.D. theses on that in the 1960s. Edgar Mitchell
types
We all know the types who listen to Pete Seeger songs; even Pete admits they aren't interesting. P. J. O'Rourke
types
To be honest, I enjoy all different types of films and experiences. Abbie Cornish
types
I've been charged with misappropriation of funds or misuse of two types of funds. Chen Shui-bian
types
There are two different types of leader. A person can either be like a thermometer or a thermostat. A thermometer will tell you what the temperature is. A thermostat will not only tell you what the temperature is, but it'll move you to the temperature you need to get to. Kevin McCarthy
types
There's always going to be short-term fluctuations. But we think they're going to do well in all types of markets. Dan Ahrens
types vicious
I just don't think I've had the desire yet to write a vicious animal - like a dog-gone-bad or anything - where I do feel that I need a balance of all types of humans. Sara Gruen
version
For the Greeks, there was no single canonical version of creation, but a number of overlapping stories. Neil MacGregor
version
But there is only one version of the truth, right? Theresa Klein
versions
Yes, I am aware that I am the gayer version of Jeff Lewis. Daniel Tosh
version younger
He's kind of like a younger version of Brett Favre. Mike Rucker
version
We're now the (junior varsity) version of that, Paul Rudd
versions
We've done so many versions of this song. Nancy Wilson
version
If something comes around that would be a challenge, then that would be wonderful. But if it's a watered-down version of something I've already done, I'd rather do something else. Rene Russo
version visit
The new CMC version removes the need for an administrator to visit each site. Mark Lewis
version
If you want a long version of the inaugural address, come on Tuesday. Jon Corzine