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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics.
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online.
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services.
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts.
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters.
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here,
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof.
centers disease except facility fact highly locked remarkable scourge secure similarly stored thousands tiny vanished vault
It is a remarkable fact that smallpox, a scourge for thousands of years, has now vanished from the earth, except for two tiny vials, one locked in a highly secure facility at the Centers for Disease Control, in Atlanta, and another stored in a similarly secure vault in Siberia. Michael Specter
center feelings
I don't have the feelings of self-worth that a woman should have... and that's been the center of a lot of my mistakes and a lot of my pain. Monica Lewinsky
center children coming emergency increase rising seeing
We are seeing a rising increase in children coming through our children's emergency center with injuries.
center importance microsoft partners people presenting push research value
We started the push by presenting to partners the importance of people being at the center of how Microsoft delivers value in research and development and for customers.
centers clearly convention giving market space talking winners
We're talking about a market where convention centers are giving their space away. There clearly will be winners and losers.
center controls feet fit form game jon less midfield minute point solid source start steve takes
We start a lot form Tom's feet at center back. Stefan takes over at the midfield and controls things from that point on. He's more or less the distribution source for everything. And Jon and Steve are just really solid workhorses in the midfield. They could play in every minute of every game and through overtime. They're just real fit specimens.
center cushion game guy terrible throw
We spotted him that one run. My freakin' terrible throw went to center field. Give a guy like that a one-run cushion when he's got his 'A' game . . . that's tough.
center consider county crosses district downtown elected front hospital line mind money nearest notice plan putting sides texas trauma travel white
When you travel through Montgomery County and notice the white crosses on the sides of the roads, keep in mind that the nearest trauma center to each cross is downtown Houston. The 2007 Texas Legislature will consider appropriating money for more trauma centers. If elected to the hospital district board, I plan on putting Montgomery County at the front of the line for one of these new facilities.
centers death football four halftime others polling running taliban voting women
When you think four years ago Taliban were here, women were being stoned to death at halftime at football games, now you have women running polling centers and women voting and men voting and, I think, each one voting for some of the others as well.
four last match proved ways won
We've won one game. We won four last year. We've got a ways to go before we match last year. We haven't proved anything. J. Taylor
four pages scripts
I did three or four weeks of work on 'Godzilla;' it wasn't a page-one rewrite or anything like that. The term is 'script doctoring,' is what I did on it. David S. Goyer
four guards looking plays using
UNLV plays four guards. So using four guards was something we were looking at doing anyway.
four major played players proud
We are proud to have four players who played a major part in Wednesday's success.
four great last learn practicing
We are practicing with Hartland and they will get us prepared. They've been there the last four years and we should learn from them. They are a great program. B. F. Skinner
fourth half later left moved second third
We usually just have two forwards up top. But later in the second half I moved up a third one, and with about 1:45 left I moved in a fourth one. Kyle Smith
four larger whim
We started this on a whim four years ago. We don't want to make it any larger than it is. It really is a lot of fun.
fourth offensive options struggled third
We struggled to find another offensive weapon. Their third and fourth options made shots, and we're not that deep.
four large plays shows
We are a fluid, but large group. We do a lot of plays and four shows a years.
helping-someone achievement saving
Helping someone come to a saving knowledge of Christ is the greatest achievement possible. Charles Stanley
helping conservation protect
The more you know about a species, the more you understand about how better to help protect them. Alan Clark
help understand
We want them to understand we're here to help and do everything we can, Mike Harris
help organize
We want to see how we can help organize the transfer. Javier Solana
helping-others names way
Helping others is a question of being genuine and projecting that genuineness to others. This way of being doesn't have to have a title or a name particularly. It is just being ultimately decent. Chogyam Trungpa
helping conspiracy crime
Prosecutors tend to love conspiracy charges because the rules of evidence are easier, meaning you can get more in to help prove a crime. David Shuster
helping-someone stories sometimes
I love helping someone else tell their story, but I like being the storyteller sometimes. David Schwimmer
helping ability
All of those measures of relationships that you have in your life help feed your and inform your ability to act. David Koechner
helping help-me help-yourself
Seriously? You won’t help me?” “Help yourself get killed? No, I won’t. Dave Barry
management function greater
The smaller the function, the greater the management. C. Northcote Parkinson
management terrorism torture
Shamefully we now learn that Saddam's torture chambers reopened under new management, U.S. management. Edward Kennedy
management labor position
I will not be in the position of having management dictated to by labor. Charles M. Schwab
management son
Unfortunately, my son is not on the management team.
management sole folly
Anger and folly walk cheek by sole. Benjamin Franklin
management employee knows
Your employees know each other better than they know you. Ben Horowitz
management behavior profit
Shareholders have the right and obligation to set the parameters of corporate behavior within which management pursues profit. Eliot Spitzer
management reason revision sales sony targets
So far, Sony management has no reason to make any revision in sales targets for the PlayStation,
management respond structure terms
This streamlines the management structure in terms of the way we respond to our owners. Mark Siegel
network shifting social word
Where I do my word processing, how I collaborate, maintaining my social network . . . those things are shifting away from Microsoft.
networking building-wealth essentials
Networking is an essential part of building wealth. Armstrong Williams
network pay
Univision is the only network where you pay for more, not for less.
networks political realize stripped television work
should be stripped of their non-profit status, and television networks who work with them should realize they are working with a political organization, not an educational organization. Ralph Nader
network
She actually started the women's network in this town, Donna Shalala
networks percent storage
Seventy-five percent of our networks are storage related. Mark E. Smith
network offering providing represent services unique
We are providing the broadest offering with the most flexibility for our network operators. Each of these services represent something unique to the operator.
networking social utilize
I really utilize all of my social networking sites. Bethany Mota
network quebec support
My support network and my friends are here. I like Quebec a lot.
operations otherwise risk transform ultimately
Ultimately it's going to be better for the patient. It's going to transform otherwise high-risk operations into lower-risk operations. John Byrne
operations stop
There is a possibility that we will have to stop operations by the end of the year.
operations system
Basically, you've got one and two in programming and one and two in system operations now all interconnected in a little knot.
operations performed
I feel that the operations could and should have been performed a lot sooner,
operations preparing since
We've been preparing for such operations ever since 2003.
operations ruling similar since
But since they have been a part of similar operations previously we are not ruling out the possibility.
operations
We think that cross-border operations would be unwise. E. O. Wilson
operations voting
Voting operations (in the countryside) are normal, with some exceptions.
operations tend
when it comes to operations on that continent, we tend to do it on the cheap. Kofi Annan
output slightly weaker worry
Output was slightly weaker than expected, but I wouldn't worry too much.
output prices pricing rise
The rise in output prices confirms signs... that firms are clawing back some pricing power.
reduced stopped
We've reduced it significantly ... but I don't think we've stopped it completely. Mike Adams
reduce simply
Most of us working on poverty alleviation simply want to know, 'How much poverty can I reduce for every dollar I donate?' Leila Janah
reduce
You'd have to reduce a whole lot of ammonia before you get any benefit. David Mitchell
reduced saying test
We're not saying let's make everything easier. There will be the need for a new test because of the new standards, but they have not been reduced in difficulty.
reduced
Although sometimes the morbid is also the transcendent, the transcendent cannot be reduced to the morbid. Siri Hustvedt
reduced
Glory comes too late, after one as been reduced to ashes.
reduce
If they are making that much profit, they should reduce rates.
reduce save trying
We're trying to reduce that and save lives.
reduce wasteful
As a taxpayer, I want to assure you that Republicans are doing everything we can to reduce wasteful spending. Jeff Miller
steps backing-up steady
History has spurts and then is steady, and then maybe even backing up a step, and then forward again. Alan Bean
steps surprise reader
I really like it when you can step outside of what's come before and find a surprise for the reader and find a surprise for yourself. Dave Gibbons
steps tough push-yourself
You take yourself to a place where you've got absolutely nothing left and then you find out you have to push yourself one more step. That's a tough place to be in. Bryan Clay
steps comfort grows
It is only when You really STEP OUT of Your comfort zone that You GROW. Bear Grylls
steps problem illegal
Illegal immigrants are already a very big problem for us. We are already taking big steps to disallow illegal immigrants from coming in. Antonis Samaras
steps commencement experiments
One failed experiment is one step closer to Success Denzel Washington
steps should
Until we see what we are, we cannot take steps to become what we should be. Charlotte Perkins Gilman
steps looks hard
It's hard to see things when you're too close. Take a step back and look. Bob Ross
steps roles muhammad
When a 'Life of Brian' comes out with Muhammad in the lead role, directed by an Arab equivalent of Theo van Gogh, it will be a huge step forward. Ayaan Hirsi Ali
systems
I think you'll see very aggressively priced systems out there. Paul Otellini
systems weather
Fortunately, the weather did end up cooperating, and it's all systems go.
systems-change consciousness individual
As one individual changes, the system changes. Ram Dass
systems
Some of our systems are 20, 30, 40 years old. We need to modernize them, and it's not cheap.
systems
We've got a lot of new systems going.
systems terrible widespread
It would have been terrible (without the widespread patching). That got a lot of systems fixed.
systems-change belief circumstances
External circumstances will not change until internal belief systems change. Myles Munroe
systems
There's a lot of systems on (boats). They're complicated.
three four finished
In 1980 I finished three or four times in seventh place. Alain Prost
three balls easy
The three-ball is an easy shot if you're uncontested, but when they know you can shoot, it's a lot harder to get off. Chris Copeland
three essentials action
There are three essential factors in all human activity: spirit, materials, and action. Chiang Kai-shek
three kind i-can
I can find only three kinds of business in the Universe: mine, yours, and God's. Byron Katie
three england beats
When you beat Arsenal, they are a good three points. Bryan Robson
three
The other three have really made strides. They're consistently getting better.
three
We've already got three up on the board. Steve Alford
three moments hours
Preferred three hours quicker over one moment late. William Shakespeare
three kind persons
Before repeating something bad about another person, ask yourself these three questions: Is it true? Is it necessary for me to tell it? Is it kind to tell it?
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed.
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent.
time two black
Time,- that black and narrow isthmus between two eternities.
time looks one-thing
To look back to antiquity is one thing, to go back to it is another.
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death.
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away.
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends.
tying
I would not like to say anything at this stage. There are some clues... We are tying these together,