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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
body damp
A demd, damp, moist, unpleasant body! Charles Dickens
body culture clock
A less 'brainy-culture' would learn to synchronise its body rhythms rather than its clocks. Alan Watts
body pieces granted
The day I take either my body or my work for granted will be the day you hear that I've smashed every inch of myself to pieces. Akshay Kumar
body
I'm thrilled with my body of work. Chris Cooper
body demand pay
Our bodies demand our attention; our bodies demand that we actually pay attention to what is going on with our lives. Chogyam Trungpa
body spirit good-things
The spirit of dance is an amazing thing. When the body and the spirit meet, it's a good thing. Chita Rivera
body needs humans
The adornment of the body is a human need. David LaChapelle
body needs materialistic
The adornment of the body is a human need. I don't see anything superficial about it unless your life becomes very materialistic. David LaChapelle
body towels pounds
I've gained a few pounds around the middle. The only lower body garments I own that still fit me comfortably are towels. Dave Barry
dave fraternity great simply special surpass tradition
What's special is the great tradition in our program. To be in the same fraternity as Dave Gunther - and surpass him - is simply great. Rich Glas
dave felt known perfect relationship
What's perfect about our relationship is that I've known Dave for two years now, and I've never once been disappointed or felt like he let me down or did something I disapproved of. JoLaine Jones
dave folks fred hilton jeff veronica
For tech, I like the 'DailySearchCast', 'TWiT' and anything Veronica Belmont does on CNET. I think Perez Hilton is a riot, and the rest of my consumption is by people: Folks like Dave Winer, Fred Wilson, Mark Cuban, Brian Alvey, Jeff Jarvis, Xeni Jardin, etc. Jason Calacanis
dave finish given great himself kings manager moments nice season
Luc himself has had discussions with (general manager Dave Taylor) and said he was disappointed. But what else can we do? He has put in a lot of years, and given a lot of great moments to Kings fans. So it would be nice to see him finish the season playing. Pat Brisson
dave kindness learn personal point priority situation
On a personal level, that's not the kind of situation I want to be in, having to relearn someone or have someone learn me at this point in my career. But this is one of those nothing-you-can-do-about-it situations. ... The priority is and the important part is Dave is OK. Curt Schilling
dave figure gone repeatedly stuff tried
We have repeatedly tried to get Dave to figure out what he'd like to do with this stuff and it hasn't really gone anywhere. Doug Herzog
dave
A lot like Dave Matthews or John Mayer, I kind of stick with the acoustic genre. Brandon Jones
dave deal major players stay venezuela
Of course, I know about Bo Diaz - he's from Venezuela! ... I know all about the players from Venezuela - Luis Aparicio, Dave Concepcion, Andres Galarraga, the Big Cat. It's a big deal when any player from Venezuela makes it to the major leagues. But the idea is to stay there, and I'm a long way from that. Miguel Perez
dave huge last million problem tigers took worth year
(Former Tigers pitcher) Dave Mlicki made $6.2 million last year. This year he's making $750,000. Good. The problem isn't that he took a huge cut. The problem is he was never worth $6 million. Doug Pappas
destined
I was persuaded now that I was destined to lead a life on the Plains. Buffalo Bill
destined foster guarantee hope permanent population segment spent
When we foster an economy without hope, we guarantee that a segment of our population will be destined to know homelessness on a permanent basis, and not for the one night I voluntarily spent at a shelter. Jackie Speier
destined hard managers people
I always thought there were some people who were just destined to be disengaged in their jobs because that was their personality, and no matter how hard managers tried, there wasn't much they could do with some of those people. Tom Rath
destined destiny determined
Some are destined to succeed, some are determined to succeed. H. Tejomayananda
destined european gas ground information russian shows ukraine
We have information from the ground that shows Ukraine has started illegally siphoning off Russian gas destined for European consumers. Sergei Kupriyanov
destined girl growing harder incredibly knew nickname prove tells time work
I knew from the time I was a young girl that I was destined to be a writer. I'm incredibly stubborn. The more someone tells me I can't do something, the harder I work to prove them wrong. My father's nickname for me when I was growing up was 'Hardhead.' Lori Wilde
destined destiny drown man proverbs
If a man is destined to drown, he will drown even in a spoonful of water. Yiddish Proverbs
destined felt saw
I saw Roland Barthes's 'Mourning Diary' at a bookshop, and I felt it was like I was destined to see the book. I read it all in one go while I was in the shop. The book was mind-blowing. Go Ah-sung
destined monkey slippery trees
The day the monkey is destined to die, all the trees get slippery African Proverb
early lots market options people uniquely watch work
Try out lots of different options early in your career. Then watch the responses: how you feel, what the market values, what people appreciate about you. It's the only way to find work that's uniquely right for you. Lisa Gansky
early pleased signals
We are pleased with the early signals this year, John Eyler
early fourth freshmen quarter
We started subbing and early in the fourth quarter we had some freshmen on the field. Pat Scelza
early easy good job maintain playing road start tough
We started really well. Playing on the road isn't easy and getting a good start is so important and we really did a good job early on. We didn't maintain the intensity, but after a start like that, it is tough to keep up that level. Curt Fredrickson
early executing good half looks missed open second shots
We started out well, executing and getting open shots in rhythm. They crawled back into it right at the end of the first half, and in the second half we got some good looks early but missed them. Jack Schrader
early guys identify season struggled team trying
We struggled early on with our team trying to identify their roles. That is what the early season and midseason tournaments are for. The guys have done that. Chris Renner
early five hopefully key looking middle peak reason row time valley win
We are looking to make it five in a row after this match. The key is to peak at the right time and to hopefully peak in the early to middle of April. There is no reason why we can't win the Valley this year. Greg Kennett
early held rest struggled
We struggled early but otherwise, we held our own the rest of the way. Curtis Brown
early fixing turkeys
We started fixing the place up, probably in October. We put our first turkeys on the place in early December. Rich Rogers
given no-hope pledge
God has given no pledge which He will not redeem, and encouraged no hope which He will not fulfill. Charles Spurgeon
given guy guys perception
The perception now is that (Woods) is still the guy to beat. But I don't think guys think it's a given that he's going to win. Lee Janzen
given park rules
We've already given them an extension. It's really simple: The rules of the park have to be followed. Sharon Stewart
given life lived name people talk tony
I hate it when people talk about Tony Curtis and say: 'His real name was Bernie Schwartz... ' That was just the name that he was given at birth. It's not the person he lived his life with, and became. Nicolas Roeg
given movies sad
A lot of my movies have come to be thought about only years after the fact, and I'm sad about that but also happy about it in a way, as it's given them longevity. Nicolas Roeg
given relevant considering
I have given up considering happiness as relevant. Edward Gorey
given hoard wealth
Wealth that you hoard is not yours; wealth that you have given is really yours. Sathya Baba
given heck love sharks shocked
What the Sharks did, it shocked the heck out of me. We've always been rivals, but I think they know how much I love this game, and how much I've given to it. Luc Robitaille
given
We have assumed control where once we worked with what we were given. Bill McKibben
later-in-life life-is-hard trying
Trying to manage diabetes is hard because if you don't, there are consequences you'll have to deal with later in life. Bryan Adams
later-in-life handsome
As I would learn later in life, money makes you extremely handsome. Mark Cuban
later-in-life fame
It's probably healthier to find fame later in life. Bill Nighy
later school
When he got to the school, they would not let him in and he was later told Christopher had been shot. Mark Nation
later line list sit year
We're going to sit down later this year and come up with a list of the (water line problems) we know about that we just haven't done anything on. Lyle Thomas
later
We're not anticipating problems, other than that we're getting them later than we expected. Kathy Miller
later offer opportunity raise
Macquarie is stalling for time. There's always the opportunity to raise the offer later on. Michael Long
later life perhaps shelves side
There are books on our shelves we haven't read and doubtless never will, that each of us has probably put to one side in the belief that we will read them later on, perhaps even in another life. Umberto Eco
later learned men nobody save shot
Later we learned that it was one of our own men hanging on the wire. Nobody could do anything for him; two men had already tried to save him, only to be shot themselves. Ernst Toller
pay attention share
I've bought QPP shares but unfortunately both times I bought it they immediately dropped by over 10p. Do you pay much attention to the dealing notes? Alan Green
pay attention objects
Faith is occupied with the Object upon which it rests and pays no attention to itself at all. Aiden Wilson Tozer
pay ifs
I would pay to do what I do if I had to. David McCullough
pay debt turns
As it turns out, we don't "all" have to pay our debts. Only some of us do. David Graeber
payroll-tax taxes payroll
I've never supported a wage tax and I've never supported a payroll tax. David Dewhurst
payroll-tax taxes payroll
Ive never supported a payroll tax. David Dewhurst
pay attention use
Pay close attention to the particular thoughts you use to deprive yourself of happiness. Byron Katie
pay attention pay-attention
I said, I'm going to stand up and somebody is going to pay attention to me. Buddy Guy
pay matter taught
Courage taught me no matter how bad a crisis gets… any sound investment will eventually pay off. Carlos Slim
prices stocks turns volume
When volume drops off, prices settle down. Volume is the force that turns stocks higher. Louis Navellier
price-of-freedom vigilance stills
The price of freedom is still, and always will be, eternal vigilance. Margaret Thatcher
price stay structural
We have said that this is a structural issue, not a short-term factor, and the price is going to stay the same, Rafael Ramirez
price question successful
We know we'll be successful with this operation. The only question is the price we'll pay. Stephen Davis
priceless
Price. You're priceless. Bret Easton Ellis
price-of-success paid paid-in-full
The price of success must be paid in full, in advance. Brian Tracy
prices
One of the prices that we pay for integration was the disintegration of the black community. Ed Smith
price-tag vision tag
The grander the vision the greater the price tag. Bill Hybels
price reasonable resonate sounds
The price sounds reasonable and should resonate with consumers, Michael Gartenberg
running men roots
It is not so difficult a task to plant new truths, as to root out old errors; for there is this paradox in men, they run after that which is new, but are prejudiced in favor of that which is old. Charles Caleb Colton
running vices common
When all run by common consent into vice, none appear to do so. Charles Caleb Colton
running moving views
When all moves equally (says Pascal), nothing seems to move as in a vessel under sail; and when all run by common consent into vice, none appear to do so. He that stops first, views as from a fixed point the horrible extravagance that transports the rest. Charles Caleb Colton
running men hands
Some men are very entertaining for a first interview, but after that they are exhausted, and run out; on a second meeting we shall find them flat and monotonous; like hand-organs, we have heard all their tunes. Charles Caleb Colton
running eye two
He had but one eye and the pocket of prejudice runs in favor of two. Charles Dickens
running pain boys
I took a good deal o' pains with his eddication, sir; let him run in the streets when he was very young, and shift for hisself. It's the only way to make a boy sharp, sir. Charles Dickens
running church-bells religion
Some wish to live within the sound of a chapel bell, I want to run a rescue shop within a yard of Hell. Charles Studd
running europe usa
My gut feeling is that SF as we know it today is actually a heavily propagandized field that grew out of a specific set of cultural trends running in the USA and Europe between 1918 and 1950, during the post-imperial modernization period. Charles Stross
running wall real
Humans are not as unsophisticated as mulch wrigglers, they can see the writing on the wall. Is it any surprise, that among the ones who look outward, the real debate is not over whether to run, but over how far and how fast? Charles Stross
seasons
I will never have my best season. Brian Dawkins
season six wonderful
Six and five, ... We thought 6-5 would be a wonderful season for this team. Steve Spurrier
season
We've still a lot to do before the season starts. Richard Walker
season
She's been killing it all season and is only getting better. W. S. Gilbert
season
The PD is over now. We've got a new season to play now, and we need to go 3-0 to get to where we want to be. Walter Brower
season
(We) still have a lot to accomplish. That's something to think about when the season is over. Derrick Brooks
season second worked
I worked with her on the second season of Dark Angel in Vancouver, one of my first real jobs. Ashley Scott
season seasons tale
This season has really been a tale of two seasons for me, Ricky Ford
season
We didn't come out to play, we didn't come out with any urgency. We've got to do better because, if we do this in the playoffs, the season is over. Dema Kovalenko
sports play interesting
It is interesting that Hindus, when they speak of the creation of the universe do not call it the work of God, they call it the play of God, the Vishnu lila, lila meaning play. And they look upon the whole manifestation of all the universes as a play, as a sport, as a kind of dance — lila perhaps being somewhat related to our word lilt Alan Watts
sports song thinking
I'm delighted about the track's success in the sports world, but the frustrating thing is, I don't think I got rich on it. The labels and publishers did very cheap deals on our songs. Alan Parsons
sports careers race
So in fact the only thing you can judge in this sport its the longterm. You can judge a career or a season, but not one race. Alain Prost
sports squash drivers
I was looking at the history of the sport and I couldn't understand why there have been so many good South American drivers, especially Brazilians. Alain Prost
sports winning thinking
When you win a race like this the feeling is very, very good. There have been times when I have been flat-out to finish sixth, but you can't see that from the outside. In 1980 I finished three or four times in seventh place. I pushed like mad, yet everyone was gathered around the winner and they were thinking that I was just trundling around. But that's motor racing. So in fact the only thing you can judge in this sport is the long term. You can judge a career or a season, but not one race. Alain Prost
sports thinking throwing
I don't think the discus will ever attract any interest until they let us start throwing them at one another. Al Oerter
sports team hate
I think the Cowboys are one of only two teams in all of sports that engender love and hate to that extreme. The other is the Yankees. You love the Yankees or you hate the Yankees. Al Michaels
sports vanity play
It's the bane of both the news and sports businesses, both electronic and print - 'You heard it here first!' Who cares? That's nothing but a vanity play. If it's not right, it's garbage. Al Michaels
sports believe miracle
Do you believe in miracles? Al Michaels
strong jobs men
No two things differ more than hurry and dispatch. Hurry is the mark of a weak mind, dispatch of a strong one. A weak man in office, like a squirrel in a cage, is laboring eternally, but to no purpose, and is in constant motion without getting on a job; like a turnstile, he is in everybody's way, but stops nobody; he talks a great deal, but says very little; looks into everything but sees nothing; and has a hundred irons in the fire, but very few of them are hot, and with those few that are, he only burns his fingers. Charles Caleb Colton
strong mind haste
Hurry is the mark of a weak mind, dispatch of a strong one. Charles Caleb Colton
strong party reason
He that aspires to be the head of a party will find it more difficult to please his friends than to perplex his foes. He must often act from false reasons which are weak, because he dares not avow the true reasons which are strong. Charles Caleb Colton
strong hands monsters
The mob is a monster, with the hands of Briareus, but the head of Polyphemus,--strong to execute, but blind to perceive. Charles Caleb Colton
strong advice desire
When we feel a strong desire to thrust our advice upon others, it is usually because we suspect their weakness; but we ought rather to suspect our own. Charles Caleb Colton
strong passion may
Strong as our passions are, they may be starved into submission, and conquered without being killed. Charles Caleb Colton
strong men thinking
Men of strong minds and who think for themselves, should not be discouraged on finding occasionally that some of their best ideas have been anticipated by former writers; they will neither anathematize others nor despair themselves. They will rather go on discovering things before discovered, until they are rewarded with a land hitherto unknown, an empire indisputably their own, both right of conquest and of discovery. Charles Caleb Colton
strong circles errors
Unity of opinion is indeed a glorious and desirable thing, and its circle cannot be too strong and extended, if the centre be truth; but if the centre be error, the greater the circumference, the greater the evil. Charles Caleb Colton
strong two mind
No two things differ more than hurry and despatch. Hurry is the mark of a weak mind; despatch of a strong one. Charles Caleb Colton
talking judging mind
It has been well observed that the tongue discovers the state of the mind no less than that of the body; but in either case, before the philosopher or the physician can judge, the patient must open his mouth. Charles Caleb Colton
talking world human-nature
There are prating coxcombs in the world who would rather talk than listen, although Shakespeare himself were the orator, and human nature the theme! Charles Caleb Colton
talking people realizing
People often say to me, 'I understand what you are talking about intellectually, but I don't really feel it, I don't realize it,' and I am apt to reply, 'I wonder whether you do understand it intellectually, because if you did you would also feel it.' Alan Watts
talking listening ordinary
We have somehow conned ourselves into the notion that this moment is ordinary. This now moment, in which I'm talking and you're listening, is eternity. Alan Watts
talking topics los-angeles
If you spend any time in Los Angeles, there's only one topic of conversation. Alan Rickman
talking bored actors
What is it about actors? God knows I get bored with actors talking about themselves. Alan Rickman
talking people signing
I genuinely like the people I meet at signings or the bits of public talking that I do. Alan Moore
talking today economy
I don't know where the stock market is going, but I will say this, that if it continues higher, this will do more to stimulate the economy than anything we've been talking about today or anything anybody else was talking about. Alan Greenspan
talking way communicate
It was repugnant, but it was the only way to communicate. Alain Resnais
training felt
I loved being back out on the pitch. Although I have not been in full training, I felt pretty good. David Ginola
training stardom
I've been in training for stardom. Bernie Mac
training mind taught
I didn't mind basic training. It taught me that something that seems impossible at the start can be achieved. Arnold Schwarzenegger
training adore hard
I simply adore the exhaustion that comes with training hard. Deena Kastor
training boeing film
I always liked show biz and got to make a few training films at Boeing. Bill Nye
training mind spirit
The word liberal distinguishes whatever nourishes the mind and spirit from the training which is merely practical or professional or from the trivialities which are no training at all. Alan K. Simpson
training java degrees
I fear - as far as I can tell - that most undergraduate degrees in computer science these days are basically Java vocational training. Alan Kay
training benefits enough
You benefit from getting in enough volume at the beginning of your training. Bernard Lagat
training age trying
We've been trying to sell cyclists of all ages and abilities on very detailed and demanding education and training programs designed to make them more like motorists. Bicyclists have shown they don't want this. What cyclists repeatedly tell us they do want is more safe places to ride, and it is time we listened to that message. Bill Wilkinson
understanding mind half
It is with disease of the mind, as with those of the body; we are half dead before we understand our disorder, and half cured when we do. Charles Caleb Colton
understanding vietnam realizing
As I come to understand Vietnam and what it implies about the human condition, I also realize that few humans will permit themselves such an understanding. Alan Moore
understanding sides stories
If you only hear one side of the story, you have no understanding at all. Chinua Achebe
understanding levels fox-news
There are a lot of folks at Fox News who bring a certain level of sophistication to their understanding of politics. David Shuster
understanding safe too-much
This was the consequence of seeing too much and understanding the horrible truth: No one is safe. The world is not manageable. David Sedaris
understanding realizing understood
I'd always thought that I understood this, but lately I realize that what I call "understanding" is basically just fantasizing. David Sedaris
understanding humanity different
What helps you as an actor when it comes to roles is that deeper understanding of so many different fractions of humanity. Because oftentimes, even in comedy, there is conflict. David Koechner
understanding curiosity kind
Understanding is a kind of ecstasy Carl Sagan
understanding joining magnificence
The very act of understanding is a celebration of joining, merging, even if on a very modest scale, with the magnificence of the Cosmos. Carl Sagan
workouts
When I'm touring, I have to think of workouts that don't require a gym. Miranda Lambert