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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
ants headache
Do ants get headaches? David Mitchell
ants closing kitchen
like ants in the kitchen - without closing all the holes, there is always a way in. Bill Bradley
ants asks associated extent field problems reduced rid study urban whenever
The extent to which urban runoff can be reduced or contained, problems associated with Argentine ants should diminish. Whenever I'm out in the field and someone asks what I'm doing and I tell them I study Argentine ants, the first thing they want to know is, How do I get rid of the ants from my home? David Holway
ants beat damage die head hurt people ruined wings
When they die here naturally, wings get beat up, ants eat off the head or antenna. There's so much damage it'd be a ruined species. It would hurt me more to see that specium ruined and we didn't let more people see it. Dennis Nelson
antsy people type
I'm such an antsy type of person. I can't write in a room without other people around. I write in coffee shops. Paul Haggis
ants sun gleam
What is it all but a trouble of ants in the gleam of a million million of suns? Alfred Lord Tennyson
antsy time
We were a little antsy to play the game, but at the same time you want to do too many things in the first minutes. Manu Ginobili
ants jump people
People will jump on it like ants on a muffin, Michael Hawley
ants humans human-beings
We are human beings, not ants. Jami Attenberg
asking may usual
In cases of doubtful morality, it is usual to say is there any harm in doing this? This question may sometimes be best answered by asking ourselves another; is there any harm in letting it alone? Charles Caleb Colton
asking good-enough enough
I found I wasn't asking good enough questions because I assumed I knew something. Alan Alda
ask china friendly stay
We want to stay friendly with China. We would like to ask China to be a little more transparent. Yoshinori Ono
asking-questions people understanding
If you don't understand, ask questions. If you're uncomfortable about asking questions, say you are uncomfortable about asking questions and then ask anyway. It's easy to tell when a question is coming from a good place. Then listen some more. Sometimes people just want to feel heard. Here's to possibilities of friendship and connection and understanding. Chimamanda Ngozi Adichie
asking want grumbling
What the Lord wants is that you shall go about the business to which He sets you, not asking for an easy post, nor grumbling at a hard one. Catherine Booth
asking-why television want
Nowadays, to be frank, every week is a good week for freakshow television. we might start asking, Why are there so many freaks? And why do they all want to be on television? Caitlin Moran
ask god invent minutes ourselves side ten
We can ask ourselves why we invent God, and then, ten minutes later, we invent Satan - why? Because we need him; there's something fascinating about the other side of the coin. Mads Mikkelsen
asked reason
The only reason why I know is because I get asked all the time. Darin Schreck
ask check false gives identify information people phone provide recommend respond themselves time written
The other thing is to ask the person on the phone to identify themselves and who they are working for, ... At any time they should be able to provide something in writing. We recommend that people dont respond over the phone but have information mailed to them. That gives them time to check it out and, if it is a scam, (the false organization) wont have written material. Richard Head
betrayal evil old-and-new
The religion of both Old and New Testaments is marked by fervent outspoken testimonies against evil. To speak smooth things in such a case may be sentimentalism, but it is not Christianity. It is a betrayal of the cause of truth and righteousness. Charles Spurgeon
betrayal fake elements
The fake slap invariably makes contact, adding the elements of shock and betrayal to what had previously been plain old-fashioned fear. David Sedaris
betrayal book reading
History is not the story of heroes entirely. It is often the story of cruelty and injustice and shortsightedness. There are monsters, there is evil, there is betrayal. That's why people should read Shakespeare and Dickens as well as history ~~ they will find the best, the worst, the height of noble attainment and the depths of depravity. David McCullough
betrayal rocks challenges
I find life itself provides ample and sufficient tests of my valor and mettle: illness; betrayal; fruitless searches for love; working for the abusive, the insane, and the despotic. All challenges easily as thrilling to me as scrambling over icy rock in a pair of barely adequate boots. David Rakoff
betrayal hate heart
You are going to break your promise. I understand. And I hold my hands over the ears of my heart, so that I will not hate you. Catherynne M. Valente
betrayal exercise irritation
I know that disavowal is an unusal form of betrayal. From the outside it is impossible to tell if you are disowning someone or simply exercising discretion, being considerate, avoiding embarrassments and sources of irritation. But you, who are doing the disowning, you know what you're doing. And disavowal pulls the underpinnings away from a relationship just as surely as other more flamboyant types of betrayal. Bernhard Schlink
betrayal men mind
Man is a mind betrayed, not served, by his organs. Edmond de Goncourt
betrayal play ideas
I'm trying to take culture and put it onstage, demonstrate it is capable of sustaining you. There is no idea that can't be contained by life: Asian life, European life, certainly black life. My plays are about love, honor, duty, betrayal - things humans have written about since the beginning of time. August Wilson
betrayal thinking play
I think the play offers (white Americans) a different way to look at black Americans For instance, in 'Fences' they see a garbageman, a person they don't really look at, although they see a garbageman every day. By looking at Troy's life, white people find out that the content of this black garbageman's life is affected by the same things- love, honor, beauty, betrayal, duty. Recognizing that these things are as much part of his life as theirs can affect how they think about and deal with black people in their lives. August Wilson
clues events final found involve large leave multiple smaller steps work
We found that many large introns are removed by multiple recursive splicing steps, ... These steps involve the sequential excision of smaller subfragments. Our work also indicates that most recursive splicing events leave no clues in the final mRNA. This is why they have not been detected before now. Javier Lopez
clues letting people somehow
People are always surprised to see clues to my being a normal kind of guy. As if I'm somehow letting the team down. Nick Cave
clues damaged evidence fires gives indicator physical totally
We are able to get a lot of physical evidence and clues in there because of, it's not totally damaged and that gives us an indicator also of how the fires were set. Jim Cavanaugh
clues confirm search storage
Mr. Burke had a storage locker. We executed a search warrant to see if there were any clues to confirm him as the bomber. Linda Bowman
clues department media orlando picked police scent sharing strongest
One of the two strongest clues that the Orlando Police Department is sharing with the media is the scent that was picked up in the woods. Samantha Knapp
clues domestic economic four looking market news next percent point surprises
I don't think we'll get any big surprises in the economic news next week, ... What the market will be looking for are any clues that point to anything other than four percent GDP (gross domestic product) growth. James Awad
clues paintings states united
I absorbed as many Impressionist paintings as I could, in Parisian museums and in many museums in the United States and in books, looking for clues to architecture, clothing, settings. Susan Vreeland
clues company internet mtv reach television tv
From the Internet to television to radio, Viacom is going to be there, ... It is the only company that can reach every demographic from (children's TV program) Blue's Clues to MTV to CBS. Mel Karmazin
clues identify physicians proper
We wanted to see if physicians could identify the clues that were provided, so that they could make the proper diagnosis. Stephen Sisson
discovery action motive
We are not more ingenious in searching out bad motives for good actions when performed by others, than good motives for bad actions when performed by ourselves. Charles Caleb Colton
discovery heaven mystery
We must leave the discovery of this mystery, like all others, to time, and accident, and Heaven's pleasure. Charles Dickens
discovery people life-is
But one of the things I learned from improvising is that all of life is an improvisation, whether you like it or not. Some of the greatest scientific discoveries of the 20th century came out of people dropping things. Alan Arkin
discovery serendipity
Some of the greatest things, as I understand, they have come about by serendipity, the greatest discoveries Alan Alda
discovery bravery arrogance
The discovery of magic can happen only when we transcend our embarrassment about being alive, when we have the bravery to proclaim the goodness and dignity of human life, without either hesitation or arrogance. Then magic can descend onto our existence. Chogyam Trungpa
discovery stories exciting
FCU's PLS discovery has quickly become one of the most exciting stories in the uranium sector. David Talbot
discovery self cosmos
We are made of stellar ash. Our origin and evolution have been tied to distant cosmic events. The exploration of the cosmos is a voyage of self-discovery. Carl Sagan
discovering happened katie
Forgiveness is discovering that what you thought happened, didn’t. Byron Katie
discovery giving surprise
We had avoided discovery by the Sioux scouts, and we were confident of giving them a complete surprise. Buffalo Bill
easily fighting great kept kids mentally plugging position tent tough
We're mentally tough and we were not going to go away. We got down 10 and could have easily folded the tent on the big stage. The kids just kept fighting and plugging away and got us back into that thing. They put us in a great position at halftime. Tony Vis
easily easy unless
Unless it comes down really hard, it'll be very easy to manage. It'll be easily treatable with salt. David Buck
easily life seniors york
Life in New York can be so, I don't know, chaotic, overwhelming, busy, frantic, and often, seniors can easily get overlooked. Aaron Lazar
easily lives
We can easily get our lives out of balance. Joseph B. Wirthlin
easily good hear peace reach since talk time true
True there has been more talk of peace since 1945 than, I should think, at any other time in history. At least we hear more and read more about it because man's words, for good or ill, can now so easily reach the millions. Lester B. Pearson
easily excellent food
A first date should be elegant. In comfortable surroundings. A place with excellent food, where you can talk easily and get to know each other. Oleg Cassini
easily mexican shuns therefore
The Mexican succumbs very easily to sentimental effusions, and therefore he shuns them. Octavio Paz
easily outcome realizing
I could easily go one or two days without realizing that I'm so, so hungry. That's the negative outcome of what I've become. Takeru Kobayashi
easily peace whose
He will easily be content and at peace, whose conscience is pure. Thomas a Kempis
facts may opinion
You may alter an opinion, but you cannot alter a # fact . Charles Spurgeon
factor growth leading robert since success thank valuable vision
We want to thank Robert for his valuable contribution to the Company's development and growth since its inception, ... His entrepreneurial vision has been a leading factor in our success to date. Glenn Parker
facts embarrassing theft
[A] great embarrassing fact… haunts all attempts to represent the market as the highest form of human freedom: that historically, impersonal, commercial markets originate in theft. David Graeber
facts economic globalization
Globalization is a fact of economic life Carlos Salinas de Gortari
facts sacred comment
Comment is free but facts are sacred. C. P. Scott
facts republican celebrate
Well, I'm celebrating the fact that Republicans are doing better with women. Cathy McMorris Rodgers
fact feels funny might mug people twice wake
I wake up every day and look at my own ugly mug in the mirror and don't think twice about it. The fact that other people might want to look at me still feels funny. It's flattering, but funny. Luke Bracey
fact positives truth
The positives are closure. The fact is we participated with an ineligible player. That's the truth. You can't sugar-coat that. Gene Smith
fact last proud
We are proud of the fact that we surpassed last year's donation. Robert Fraser
farther good job late matching night played step team
We were a step late all night long. We did not do a good job of matching their intensity. They played hard. They played like a team that wanted to go a little farther (in the playoffs). Tony Woody
farther guys sitting station until work
When I was on the radio, I used to be able to go a lot farther than I can now. You don't really remember until you're on the radio again, sometimes in your old radio station and sitting with the guys you used to work with and you go, 'Oh yeah, I can't say these things anymore. I'm handcuffed.' Jimmy Kimmel
farther frustrated hardly music played playing
To play music, you have to understand it. I didn't understand 'Topographic Oceans.' That's why I hardly played on it. It frustrated me no end - and playing the whole thing on tour, I got farther and farther away from it. Rick Wakeman
farther kept stopped throughout
Throughout the at-bat I just kept going farther and farther. I wanted to see how much they would let me have before they stopped me. They never did, and I told Skins, 'I can take this. Grady Sizemore
farther kept stopped throughout
Throughout the at-bat, I just kept going farther and farther, ... I wanted to see how much they would let me have before they stopped me. They never did, and I told Skins, 'I can take this.' Grady Sizemore
farther man polish-novelist
I had ambition not only to go farther than any man had ever been before, but as far as it was possible for a man to go. Joseph Conrad
farther finally happy trying
We're happy to go to state. We've been trying to go farther and farther each year. And we finally made it this year. Angelica Sails
farther nervous trying
We're anxiously trying to get it reinstated ... We're getting more nervous the farther away we get. Peter Gregg
farther
Now I'm this far up the ladder and I've got so much farther to go with what I want to achieve with it. Karl Urban
foresee healthy stay
I foresee us -- if we stay healthy -- being right in the hunt. Jerrad Jeske
foresee june metal ounce per precious reach
I foresee that the precious metal would reach $800 per ounce by June this year. Tanvir Abid
foresee
I foresee a lot of opportunities for suppliers. Russell Vandiver
foresee next
I don't foresee this going into next week. Michael Cuddyer
foresee governor run situation
He does not foresee a situation in which he would run for governor at this time, Ken Salazar
foresee results trivial
You can not foresee the results of even the most trivial act. Wallace Wattles
foresee profoundly shortcuts
When we try and take shortcuts that's when we get outscored. I'd be profoundly disappointed if we (took shortcuts) again. I can't foresee that happening. Tom Elwood
foresee injuries knew minor position short
We got in that position because of injuries and don't think we didn't know we were short in the minor leagues. We knew that, but who is going to foresee injuries? Frank Robinson
foresee people time
People in the industry foresee a time in which, for many people, the only thing they'll need on a computer is a browser. Mitch Kapor
intelligence intellectual useless
It is only the constant exertion and working of our sensitive, intellectual, moral, and physical machinery that keeps us from rusting, and so becoming useless. Charles Simmons
intelligence politics fool
I will keep where there is wit stirring, and leave the faction of fools. William Shakespeare
intelligence
There is no such thing as Intelligence; one has intelligence of this or that. One must have intelligence only for what one is doing. Edgar Degas
intelligence may courses
Of course not. After all, I may be wrong. Bertrand Russell
intelligence run
Let's just say that more intelligence is needed. You can't just run up and do this, you have to think about it. Billy Higgins
intelligence music women
In the music industry, intelligence in women is undervalued. Bat for Lashes
intelligence-services numbers together
We haven't really had the time yet to pore through all those records in Baghdad. We'll find ample evidence confirming the link, that is the connection if you will between al Qaida and the Iraqi intelligence services. They have worked together on a number of occasions. Dick Cheney
intelligence intelligence-and-intellectuals luck proverbs
You don't need intelligence to have luck, but you do need luck to have intelligence. Jewish Proverb
intelligence-gathering flaws sept-11
But it is equally incontrovertible that if our intelligence gathering process is seriously flawed, we had better find out and find out fast if we are to avoid another Sept. 11. Adam Schiff
millennia people phenomena religious war
People sense that our reaction to phenomena such as epidemics or religious war is not that different to how we reacted to plagues or to battles a millennia ago. Karen Maitland
millennials earth kingdoms
But the Jews will also be believers, so you can say that all the saints, both gentiles and Jews, will go into the millennial kingdom and populate the earth. Tim LaHaye
million mind run
When you take away the phone and e-mail and you don't have a million things to run around to, it allows your mind the space to think more expansively about the things that matter. Ewan McGregor
million today worth
What $1 million is worth today is not the same as it will be worth in 2030. Harold Jones
million perry rick win word
We're going to have to use the word million in the plural, but with that being said, we're not going to have to outspend Rick Perry to win this thing. Jason Stanford
millions
I want to sell out arenas and sell millions of records. Katy Perry
million returned three troops vietnam
Three years into American involvement in Vietnam they were up to 500,000 troops in-country and there probably were already a million who had returned home. Michael Schwartz
million next project received three
Three years ago we received 7 million applications. This year, we project 13 million applications. Next year, 15 million. Frank Moss
million movies offered
Luckily, I haven't been offered any $300 million movies that I hate. So I'm not in that predicament just yet. James Frecheville
millions
Let's just say it would be in the millions of dollars, F. Stone
million people promise represent senate texans truth
And the people I have been accountable to every single day in the Senate are the 27 million Texans who I represent and I made a promise to them that I make to you today, which is, if I am elected, every single day I will do two things: tell the truth, and do what I said I would do. Ted Cruz
recognize sensitive
We're sensitive to consumers, we recognize there's more out of people's pocketbooks, Tim Hearn
recognize support
At Walmart, we recognize the need to support the development of our nation's youth. Sylvia Mathews Burwell
recognizes trying weaker
She recognizes me. She's weaker but she's still trying to talk. Suzanne Vitadamo
recognizes
The only place I really get recognized is at Ralphs. Whenever I'm in L.A., I go to Ralphs, and for some reason, everyone there recognizes me. Lauren Lee Smith
recognized students taking
We're 20 to 40 students away from being a Recognized district. It was close, but we're not taking any chances. Brad Lancaster
recognized
The only ones those certifications are recognized by are the associations who give them. Ted Nelson
recognized
I seem to get recognized more in London and Europe than over here in the States. David Boreanaz
recognize tried
I've tried to recognize my wife's individuality, her personality, her desires, her background, her ambitions. Gordon B. Hinckley
recognized wants
Everyone wants to be seen. Everyone wants to be heard. Everyone wants to be recognized as the person that they are and not a stereotype or an image. Loretta Lynch
trying sometimes failing
Try to do unto others as you would have them do to you, and do not be discouraged if they fail sometimes. It is much better that they should fail than you should. Charles Dickens
trying want scripture
Dear friends, whenever you want to understand a text of Scripture, try to read the original Charles Spurgeon
trying littles reason-why
The great reason why we have so little good preaching is that we have so little piety. To be eloquent one must be in earnest; he must not only act as if he were in earnest, or try to be in earnest, but be in earnest. Charles Spurgeon
trying world term
A myth is an image in terms of which we try to make sense of the world. Alan Watts
trying world
But we try to pretend, you see, that the external world exists altogether independently of us. Alan Watts
trying way hurrying
Hurrying and delaying are alike ways of trying to resist the present. Alan Watts
trying rooms natural
That Beatle euphoria has always been there, and it's hard to be in a room with a Beatle and try to be totally natural. You never shake that off. Alan Parsons
trying entertainment television
I try to do things in comics that cannot be repeated by television, by movies, by interactive entertainment. Alan Moore
trying acting together
Improvisation sometimes seemed more like jazz than acting, like verbal jazz, with the actors playing a theme back and forth, and then introducing another theme, incorporating it, somehow trying to work their way all together to a meaning of some kind, or at least a conclusion. Alan Arkin
work quality may
Although profoundly "inconsequential," the Zen experience has consequences in the sense that it may be applied in any direction, to any conceivable human activity, and that wherever it is so applied it lends an unmistakable quality to the work. Alan Watts
work apology giving
Give a civil servant a good case and he'll wreck it with clichés, bad punctuation, double negatives, and convoluted apology. Alan Clark
work mean doing-nothing
If I am doing nothing, I like to be doing nothing to some purpose. That is what leisure means. Alan Bennett
work sleep thinking
A gentleman ... sleeps at his work. That's what work's for. Why do you think they have the SILENCE notices in the library? So as not to disturb me in my little nook behind the biography shelves. Alan Ayckbourn
work play able
You've got to get good habits of working hard so that when that play comes up during the regular season that you're able to complete it and do it the right way. Al Kaline
work people kind
Japanese people tend to be much better adjusted to the notion of work, any kind of work, as honorable. Akio Morita
workout training cardio
I do a dance-based cardio workout infused with circuit training, and emphasizing strength and alignment. Chloe Sevigny
work-out effort feels
If I put forth a legitimate effort, then I feel like, if that doesn't work out, that's all I can do. Dave Chappelle
work-out levels mail
I always take a relationship to the next level. If that works out, I take it to the next level after that, until I finally reach that level when it becomes absolutely necessary for me to leave. Dave Chappelle