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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
ages power wisdom
The power is yours, but not the sight; / You see not upon what you tread; / You have the ages for your guide, / But not the wisdom to be led. Edwin A. Robinson
ages community people section
We want people of all ages from every section of the community to be involved. John Hutton
ages eats face skin ten time trick winter
My face and skin trick is to moisturise well in the winter time, because the weather eats up your skin, and I never go to sleep with make up on. Someone told me it ages you ten years. Kelly Rowland
ages characters eligible inevitably life likely revived time tom written
In the life of any actor or actress, there is inevitably a time when they will be eligible to act in a Tom Stoppard play. He has written a lot, and they are revived often, and there are so many characters of different ages that it was more likely I'd end up in something of his than that I wouldn't. Ed Stoppard
ages aristotle bergman human nature oneself plato serious since socrates thinkers understand
Since Socrates and Plato first speculated on the nature of the human mind, serious thinkers through the ages - from Aristotle to Descartes, from Aeschylus to Strindberg and Ingmar Bergman - have thought it wise to understand oneself and one's behavior. Eric Kandel
ages exclusive men women
We're high-end, exclusive for men and women ages 21 to 60. Tim Watkins
ages british building burnt crushes egyptian forgive granite hall heavy marbles material present produced quite relics statues successive thousand tiresome turned visited wandered weary wishing yesterday
Yesterday I went out at about twelve, and visited the British Museum; an exceedingly tiresome affair. It quite crushes a person to see so much at once; and I wandered from hall to hall with a weary and heavy heart, wishing (Heaven forgive me!) that the Elgin marbles and the frieze of the Parthenon were all burnt into lime, and that the granite Egyptian statues were hewn and squared into building stones, and that the mummies had all turned to dust, two thousand years ago; and, in fine, that all the material relics of so many successive ages had disappeared with the generations that produced them. The present is burthened too much with the past. Nathaniel Hawthorne
ages consummate deal fiction great pleasure science trying
I read a great deal of science fiction with consummate pleasure between, say, the ages of 12 and 16. Then I got away from it. In my mid- to late 20s, I started trying to write it. William Gibson
ages chewing food hugely maybe people print slow
I read hugely as a child, but I slowed up when the print got smaller. I am a very slow reader. I don't know why. Maybe it is like some people chewing their food for ages and some wolfing it down. Geraldine McCaughrean
air long joy
He was consious of a thousand odours floating in the air, each one connected with a thousand thoughts, and hopes, and joys, and cares, long, long, forgotten. Charles Dickens
air house honor
Honor is the most capricious in her rewards. She feeds us with air, and often pulls down our house, to build our monument. Charles Caleb Colton
air might physicians
Some persons will tell you, with an air of the miraculous, that they recovered although they were given over; whereas they might with more reason have said, they recovered because they were given over. Charles Caleb Colton
air should vendetta
Knowledge, like air, is vital to life. Like air, no one should be denied it. Alan Moore
air sky needs
Lots of cosy sky That God and I can share. I need air. I need air. Alan Jay Lerner
air actors eras
Certainly the movies were always in the air for me. I come from the era when actors thought it was a big deal to be in the movies. Al Pacino
airport commercial deadline open remain service view
We want to see the airport remain open to commercial service. We view this deadline (Tuesday) ... as a deadline after which we will re-evaluate where the airport stands. Kathleen Bergen
airplane thinking artist
Learning to fly an airplane taught me a way of thinking, an approach to problem-solving that was applicable and effective. Pilots are very methodical and meticulous, and artists tend not to be. Chris Carter
airports percent
Out of all the airports that are out there only about 5 percent have commercial service. Chris Brown
beings fallen few glance looked love nowadays people power stories
The power of a glance has been so much abused in love stories that it has come to be disbelieved. Few people daresay nowadays that two beings have fallen in love because they have looked at eachother. Yet that is the way love begins, and only that way. Victor Hugo
beings cloning fiction human possible question
The possible cloning of human beings is now not relegated to the world of fiction, and the question to the world is this -- what should we do with this science? James Greenwood
beings human level moral object stage strongly
We strongly object on a moral level to the destruction of human beings at any stage of development for research. Dennis Poust
beings economics fear good great greed help human machines psychology reasons swing
The great thing about behavioural psychology and economics is that they help us to see that there are actually pretty good reasons why human beings swing from greed to fear, and why we're not really calculating machines or utility-maximisers. Niall Ferguson
beings belief believe cling conducive doctrine due welfare
Whatsoever, after due examination and analysis, you find to be kind, conducive to the good, the benefit, the welfare of all beings that doctrine believe and cling to, and take it as your guide. Buddha
beings canadian human life proud
We're proud to have him. As human beings and in life and in this country, I think a big part of being Canadian is being able to forgive. Kevin Lowe
beings contact countries global human increases number obviously
With the number of countries now that have significant outbreaks of some sort, obviously there is more contact with human beings and that increases the possibility of ... a global human pandemic. Kent Hill
beings disease human life whether
When your life is threatened, whether it's by human beings or by disease or whatever, you come to appreciate life. Ayaan Hirsi Ali
beings dog help learned persuade
I learned from my dog long before I went to Gombe that we weren't the only beings with personalities. What the chimps did was help me to persuade others. Jane Goodall
chains forged
I wear the chains I forged in life. Charles Dickens
chain climbs guys rings
There are some climbs but not much for these riders. A lot of those guys will probably be going up in their big chain rings a lot of these climbs. Kurt Burkhart
chain church clear feet forest huge property sitting snapped tall trees uprooted worked
We also worked on the church property taming a forest of uprooted trees. Huge trees -- 20 feet tall -- had been snapped off and just the trunks were sitting there. We went in with a Bobcat and chain saws to clear up the church's wooded property. Dennis Johnson
chain collecting commerce commercial conducting including legal licensed local native operate respect state supply tribes
We respect the right of Native American tribes to operate commercial enterprises, and the right of licensed distributors to supply them with legal products. But in conducting commerce with non-Native American consumers, everyone in the supply chain should play by the same rules, including collecting state and local taxes. James Calvin
chains frugal preserves
Disdain the chain, preserve your freedom; and maintain your independency: be industrious and free; be frugal and free. Benjamin Franklin
chainsaw seen
I've never seen 'Texas Chainsaw Massacre', I've never seen 'Halloween', I've never seen any of the 'Friday the 13ths.' Lin Shaye
chain entertainment entire family food looking
We're looking at the entire food chain of children's and family entertainment. Andy Heyward
chain check pull tire trap
Back then the cars had a trap door that we could pull open with a chain to check our tire wear. Tim Flock
chain maybe open riding stops
I'm just riding this train as long as I can. As long as I'm having fun, I'll do it. When it stops being fun, I'll try something else. Maybe I'll open up a chain of Popeye's Chicken. Gabrielle Union
distances hold worked
We're back. That is what it used to be and we need to keep it there. It worked today, but those distances aren't going to hold up all the time. Dick Booth
distances dreams dynamism jacket man marriage marriages time travel travels
'Mr. Peanut' is not about a man who dreams of killing his wife; that's jacket copy, to me. 'Mr. Peanut' is about the dynamism of marriage and the distances - some tragic, some redemptive - that marriages travel over time, and those travels ain't always pretty. Adam Ross
distances people power remarkable tolkien travel
Because of the power of the Tolkien name, people will travel from remarkable distances to see this production. Kevin Wallace
distances guaranteed included note record stack tenure track
Note to academics: Aristarchus' track record of astronomical research would probably have guaranteed him tenure somewhere, if tenure had been invented. His stack of reprints included measuring the distances of the Moon and Sun. Seth Shostak
distances people prices sink suburbs work
For people who live in the suburbs and must commute long distances to work, their wealth will sink as energy prices rise. Robert Kiyosaki
distances drive eat meals people phone prepare
We've had people eat their meals in their sleep; prepare meals in their sleep. We've had people have phone conversations in their sleep. We've had people drive long distances in their sleep. Mark Mahowald
distances next official results send until wait
We couldn't get all our times or distances in some of the events. We will have to wait until they send us the official results next week. Paul Sadorf
distances factor measure radio telescope
We have established that the radio telescope we used, the Very Long Baseline Array, can measure distances with unprecedented accuracy--nearly a factor of 100 times better than previously accomplished. Mark Reid
distances farther
This is an important race. Do we go farther distances or shorten up? Christopher Paasch
equivalent knowledge man
Man is not weak; knowledge is more than equivalent to force. Samuel Johnson
equivalent screaming shirt tearing
Actors want to act; actors want to emote. It's like the emotional equivalent of tearing your shirt off and screaming to the heavens: you want to express, and you want to be seen to be expressing. Joel Edgerton
equivalent human
The idea that being human and having rights are equivalent - that rights are inherent - is unintelligible in a Darwinian world. Tom Stoppard
equivalent somebody tattooed
Somebody actually tattooed my face on his arm. In a couple years, that will be the equivalent of having a Screech tattoo. Chris Jericho
equivalent exercise good lose lots obedience people promising spend time weight
Lots of people make resolutions to try to spend more time with their dog, to try to take them to obedience class, to take them out for sports. It's the canine equivalent of promising that we're going to go out and exercise more ourselves, lose weight and be good and moral. Stanley Coren
equivalent feature largest mere sauces whether
Many of the Prego sauces - whether cheesy, chunky or light - have one feature in common: The largest ingredient, after tomatoes, is sugar. A mere half-cup of Prego Traditional, for instance, has the equivalent of more than two teaspoons of sugar: as much as two-plus Oreo cookies. Michael Moss
equivalent expresses found interests leaning networks proactive rather skills time
Proactive giving is what you do when you've found your passion. It expresses your values, interests and concerns. It engages not just your dollars, but also your mind, time, skills and networks - the philanthropic equivalent of leaning in, rather than leaning back. Most importantly, proactive giving is something you want to do. Laura Arrillaga-Andreessen
equivalent five glasses judge pairs policy voters
Voters can have on the equivalent of five different pairs of glasses when they judge a policy proposal. H. Hart
equivalent goals group groups law main minority personal tie
One of my personal goals was to tie each of the law school's minority groups with the equivalent group on the main campus, Darrell Jackson
examined poked
We have to get used to being examined and poked and touched. Jerry Green
examine future kinds measure needs
With these kinds of proposals, the devil is in the details. We're going to examine this realignment closely. We will fight any measure that compromises our needs - now or in the future. John B. Larson
examine felt memoir originated playing
I don't know where the idea originated that memoir writing is cathartic. For me, it's always felt like playing my own neurosurgeon, sans anesthesia. As a memoirist, you have to crack your head open and examine every uncomfortable thing in there. Koren Zailckas
examine playing transform
I examine other people's characteristics, so when I'm playing characters, I don't always have to make them me; I can transform into others. Marcia Gay Harden
examine taught
Euclid taught me that without assumptions there is no proof. Therefore, in any argument, examine the assumptions. E. T. Bell
examined financial finished obviously pleased processes reporting
We're obviously pleased to be finished with it. It's made us better. We examined all of our processes and controls, and I really think we have strengthened our financial reporting and controls. Mark Land
examine gonna wants
He's gonna go back with us. The doc wants to get an MRI on him, but he's got some ligament problems. They want to examine him more. Joe Paterno
examined issues perhaps petition recently
I think what's perhaps most disheartening about this petition is that these issues were examined recently by the board. Richard Henning
examined friday status
He has some damage. He's going to be examined Friday and we'll know more about his status after we get some more opinions. Ken Holland
examining hopefully nature reveals
I like examining the ordinary, and by doing so, one hopefully reveals the extraordinary nature within. Kevin Henkes
examining followed problem
We really followed our noses. No one was examining this problem of spontaneous pain. Sally Lawson
examining releasing
What we're examining in this investigation is if there were alternatives to automatically releasing him. Russ Marlan
examining falling points software
We have a scorecard, and there are 22 points that we go through examining how the software behaves. In this case, XCP is falling down. Sam Curry
examining famous level people sour work
It's sour grapes, I admit, I want to be more famous so people are examining my work couplet by couplet, you know what I mean? That's the level where I want to go. Frank Black
examining people process
This show is not about the process of prosecuting somebody. It's about going into this world and examining why people do what they do.. Jonathan Littman
examining hole people picked sure systems
We are examining our systems to make sure there is not some hole where people are not getting picked up. Gary Karr
examining increased lighting security side
We've increased patrols ... on that side of campus, and we're examining other things over there as well, from lighting to security fences. Mark Kelly
examining fast happened light mechanism pinned players quite shoe strong support swimming turned
Kyle's, for instance, would've happened in a swimming pool. The way that thing got pinned and turned had nothing to do with the turf whatsoever, ... What we're examining very closely, quite frankly, are the shoes. The players all want, just like the padding, as little a shoe, as light a shoe, as fast a shoe as they can get. But the shoe also is a very strong support mechanism for the foot. Brian Billick
force jones lets passing run stop stopped tee yards
We want to stop the run first and then force them into a passing game. I think that's what we did two years ago when we went up there in the rain. We stopped FSU tailback Greg Jones for 15 yards on 13 carries. That just lets you tee off on the quarterback. Thomas Carroll
force illegal labor speak support
We want to show we're part of the labor force as well. We have a right to speak up and say we don't support illegal immigration. Alex Segura
force forces-of-nature
We have become a force of nature. David Suzuki
force good percent solid work
The other thing is you need a good solid work force and 50 percent of us is female, so just play the numbers. Elizabeth Ivey
force girls needed played rushed tried
We started slow, like we usually do, but we rushed things, and tried to force them when we needed to be more patient. The girls played hard, it just didn't happen. Mike Royer
forced size struggled
We struggled with their size and their length. They forced us to make perimeter shots. Matt Benefiel
forced offensive played stopped
We stopped them from getting offensive boards. We did that, forced some turnovers and played our game. Ryan Diggs
force good percent talking work
We're talking about a good 80 percent of our work force in Charleston. Gregory Lagana
forced picked pressure
We started out sluggish, but they responded well and picked up the pressure and forced some turnovers. Joel Sullivan
mail importance receiver
E-mail importance is defined by the receiver, not the sender. Chris Alexander
mail junk minutes
If I dont get at least one e-mail every ten minutes, I feel unloved. Even junk mail makes me feel seen. Sad, I know. Sigh. Chris Abani
mail matter fans
Fan mail is one thing, but fans you meet in person are a different matter entirely. Audrey Meadows
mail
When we come to Miami, we need to just mail it in. We don't even need to stop. Bernie Bickerstaff
mail man
Unfortunately, no, ... man responsible for the mail bombings. Theodore Kaczynski
mail quite secure system
With the Hotmail breach, the mail was quite secure as it was going over the Internet. It was the back-end system that wasn't secure. Scott Schnell
mail communicate
I communicate mostly via e-mail and receive hundreds of e-mails a day. Diane von Furstenberg
mail genes ability
E-mail has some magical ability to turn off the politeness gene in a human being. Jeff Bezos
mail kind shows
I never got any kind of mail regarding whatever I did on the show. Jamie Farr
missiles deterrent
Even an inaccurate missile is quite a deterrent. Caspar Weinberger
missiles thousands
There are thousands of these surface-to-air missiles around the world. Richard Shelby
missiles moved seen zones
This is one of the things that we have seen over time, that in the no-fly zones there will be surface-to-air missiles moved in, moved around and moved out, Richard Myers
sending sure
We're making sure that we're sending the right message. Jerry Gonzalez
sending surface work
Sending Minerva to the surface did not work. Junichiro Kawaguchi
sending sounds
Sending in the commandos sounds very hip, but it isn't the whole solution. Sunita Narain
sending silly start stupid
Sending him back out there, that's a little silly to try to do something stupid with a man's career. We haven't done that to him all year, and we weren't going to start today. Ron Gardenhire
sending
I get a lot of email, so if you're sending me an email, if you want to rise above the clutter, put something on it: say, 'Hey!' Robert Scoble
sending
On reflection, I think the sending off was justified. Danny Mills
sending stopping
I was sending her all the way. There was no stopping her. Dan Carter
sending team
But we'll be sending a competitive team to the Giro. John Lelangue
sending talking
We're talking about sending him down so he can get some game-time experience. Mike Browning
spending enjoy ifs
What would you like to do if money were no object? How would you really enjoy spending your life? Alan Watts
spending born deficit-spending
I understand deficit spending. I was born in deficit spending. Al Sharpton
spending combination increase
If we increase spending, we have got to raise taxes or any combination. Bobby Scott
spending-time spending feels
Spending time outdoors makes you feel great. Elizabeth Hurley
spending
I was not interested in spending 10 years in the culture wars. Leon Wieseltier
spending
You cannot keep out of trouble by spending more than you earn. William J. H. Boetcker
spending federal-spending
Federal spending is atrocious. Jason Chaffetz
spending
I don't think anyone's pushing for spending limits in the campaign. Craig Benson
spending
know that there has to be a spending limit. Arnold Schwarzenegger
technical trained
There wasn't much technical terminology, and then, most academics are not trained in writing. And there is what is probably worse than ever before, the growing use of professional jargon. Stephen Jay Gould
technical
We want to let you use a Mac, or Windows PC, or iPad, or Android, without having to think about any of the technical details. Arash Ferdowsi
technical
We like to say at Khosla Ventures, and this is one of the reasons to do what we do, we'll take technical risks that nobody else will. Vinod Khosla
technical time various
There's always pressure on filming. There's the weather, people, various different technical problems. There's always pressure! And there's never really enough time for anything, really! Sylvester McCoy
technical
When I am hiring, I look at the technical qualifications. Michael Harris
technical
There's really not much that's technical to it, Jim Anderson
technical type value
That type of technical analysts does not have a lot of value. Scott Stewart
technical
The scholarships don't necessarily have to be used at a university. If someone wanted to go to a technical school, or even something like hairdressing school, they could use it for that, too. Tony Giarrusso
technical
That may well be a technical thing - it's something I will look at during the winter, Nick Knight
thousand conscience
Conscience is a thousand swords. William Shakespeare
thousand
To-morrow? - Why, To-morrow I may be / Myself with Yesterday's Sev'n Thousand Years. Edward Fitzgerald
thousand right-words ifs
One word is worth a thousand pictures. If it's the right word. Edward Abbey
thousands
For thousands of years, there have been lies about being gay or not being gay. If you know they're lies, you're free. Don Miguel Ruiz
thousand
A word is worth a thousand pictures. Elie Wiesel
thousand
A word is worth a thousand images. Andreas Gursky
thousands
There are tens of thousands in there who are probably going hungry, Ron Redmond
thousands wrestling
He's doing a lot more wrestling now. But sometimes it comes back because he's drilled in thousands and thousands of times. Jake Shulaw
thousand yards
I would give up one thousand yards to get a win. Derrick Brooks
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton