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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
age way young
I am not old, but my young way was never the way to age. Charles Dickens
age church body
We devote the activity of our youth to revelry and the decrepitude of our old age to repentance: and we finish the farce by bequeathing our dead bodies to the chancel, which when living, we interdicted from the church. Charles Caleb Colton
age waste excess
The excesses of our youth are drafts upon our old age. Charles Caleb Colton
age matter fairytale
In a utilitarian age, of all other times, it is a matter of grave importance that fairy tales should be respected. Charles Dickens
age pay time-is-money
I've reached an age at which I'd rather pay more for something that "just works" than roll up my sleeves, reach for a spanner, and make it work. Time is money, and the older we get the less of it we've got left. Charles Stross
age amusement serious
Pleasure, so called, is the murderer of serious thought. This is the age of excessive amusement. Everybody craves for it, like a babe for its rattle! Charles Spurgeon
agents very-good turns
I knew with Snape I was working as a double agent, as it turns out, and a very good one at that. Alan Rickman
age towns my-family
Hee Haw was probably my biggest exposure to live music at a young age, because there wasn't any live music around my town and no one in my family played instruments. Alan Jackson
age golden golden-rule
Here's my Golden Rule for a tarnished age: Be fair with others, but keep after them until they're fair with you. Alan Alda
barely happened hurricane praying stand state
We are praying that the hurricane dissipates or that it weakens. This state can barely stand what happened to it. Kathleen Blanco
barely biggest both car choice corners front happy push race team touch tremendous turns wing wrong
Unfortunately, I think we made the wrong choice on our race setup, and the Marlboro Team Penske car had a tremendous push in Turns 3 and 4. Those corners were my biggest problem. I could barely touch the throttle going through there. The team made front wing adjustments on both of our pits stops, but it didn't really help. All considering, I'm pretty happy with a fourth-place finish. Helio Castroneves
barely core meeting rural
We're barely meeting the core in rural Utah. J. M. Roberts
barely growth keeping
We're barely keeping up with the growth in Naperville and the surrounding communities, ... We need more beds. Pam Davis
barely good played
We're barely getting beat, just one or two possessions away from winning. We've played good basketball. But we haven't played consistent. Tom Halbmaier
barely drink forget life quite remember sign space sunday three
Three years ago, I used to go out a lot and I used to drink quite a lot. On a Sunday night, I'd think, 'Right, I have to sign on on Thursday, and I can't forget that' and now, into the space of one day, I'm cramming in what then I would have done in two weeks. I can barely remember my old life now. Paul Thomson
barely came hurt luckily people
When I came here I barely thought I would play as a freshman, ... But some people got hurt and luckily I got to go in. Jose Alvarado
barely few genuine remembered
I barely remembered my father; I'm confused between genuine memory and the few photographs that survived. Tom Stoppard
barely black came patch school walk
She came to school with a black eye. She had a patch over her eye. She could barely walk and she was in pain. Jerry Jones
coherent consensus everybody final quantum
Space can vibrate, space can fluctuate, space can be quantum mechanical, but what the devil is it? And, you know, everybody has their own idea about what it is, but there's no coherent final consensus on why there is space. Leonard Susskind
coherent convinced faith totally
I am totally convinced the Christian faith is the most coherent worldview around. Ravi Zacharias
coherent creeps cripple defense exhaust guided ideology instead liberals national plans rule smug
Think what evil creeps liberals would be if their plans to enfeeble the individual, exhaust the economy, impede the rule of law, and cripple national defense were guided by a coherent ideology instead of smug ignorance. P. J. O'Rourke
coherent life novels suddenly
As for writing novels - it's what I've done for 30 some-odd years. I can't suddenly say I'm going to take up golf. I need something in my life. As long as I can write a coherent sentence, I'll keep at it. Susan Isaacs
coherent market social
Basically, on the question of Europe, I want to see a social Europe, a cohesive Europe, a coherent Europe, not a free market Europe. Jeremy Corbyn
coherent fine full headache rest
I have a little headache still, but I'm a little more coherent today. With a full day's rest, I'll be fine by (Saturday's game). Jon Brockman
coherent government presented relatively
I think the government presented a relatively streamlined case. It was a pretty coherent presentation of the witnesses. Jonathan Halpern
coherent company demand huge maintain parts production spare
There is a huge demand for spare parts that only Sikorsky can meet. Without the Teamsters, the company can't maintain a coherent production schedule. Loren Thompson
coherent forced literate witty
He is forced to be literate about the illiterate, witty about the witless and coherent about the incoherent. John Crosby
everybody experience hard ice trying year
We want them to experience what it's like to be in that situation. This has been a hard year for everyone -- not just the kids, but everybody off the ice who are trying so hard to make this thing work. Trent Yawney
everybody level morning provide service three treat whether
We want to treat everybody the same, ... provide the same level of service whether it's three in the morning or three in the afternoon. David Burns
everybody helped thank
We want to thank everybody who helped us, Alan Henderson
everybody nobody sound
We want to sound like everybody and nobody at the same time. Jamie Varley
everybody losses prepared record
We want to show everybody we belong. Our record doesn't matter. All those losses prepared us for this. Alexis Karel
everybody segment
We want to see something that's going to be a win-win for everybody and not just for one segment of the population. Larry Glass
everybody firing guy jumping keeps loose relaxation telling therapist
I've always been the locker-room jokester, the fun guy, the guy who keeps it loose and easy. But also, on Sundays, the guy in that huddle jumping up and down, telling guys, 'Hey, get it going. Let's go.' Firing everybody up. So I'm part relaxation therapist and part Red Bull. Michael Strahan
everybody half million racing until
Until about 20 (laps) to go, and then everybody is going to be racing for that million and a half dollars. Greg Biffle
everybody finesse known looking program soft tough trying
We've always been known as a soft program, a finesse program -- all about speed, whatever. We're just trying to go out and show everybody this isn't the Gators that you're used to looking at. We're trying to show them that we're really tough and that we're really going to go out and play. Jarvis Herring
sentences
Make no a complete sentence. Amy Poehler
sentences
When I read a review, 90% of the review is about my lifestyle, and the last two sentences are about the record. Pete Wentz
sentences
This sentence contradicts itself - no actually it doesn't. Douglas Hofstadter
sentences
The best sentence? The shortest. Anatole France
sentences moved
I moved through the days like a severed head that finishes a sentence. Amy Hempel
sentences urged
I do not think of literature as something confessional or therapeutic. I make sentences in order to be precise about experiences and things. I am urged by many things and no things in particular. Per Petterson
sentences
There are a lot of things you can be doing with your kids. We want them to write sentences by the end of kindergarten. Michelle Green
sentences aspire
Music: what so many sentences aspire to be. Mary Oliver
sentences knows
I know all those words, but that sentence makes no sense to me. Matt Groening
sisters stocking
When I was a kid, my sisters and I used to get a little present in our stocking each day of December, usually an ornament, some sweets, or a little toy. Birgitte Hjort Sorensen
sisters spend time together travel weekends
I like to get together with my sisters and my nephews, and I try not to travel on weekends so that I can spend time with friends and family. Lacey Chabert
speaking
Where they're just speaking in tongues, like they're on a drug or something... Would I really do that if that's what it would take? Lucinda Williams
speaking
When I was a kid, I resented my grandparents not speaking the perfect English I wanted to speak. Jose Antonio Vargas
speaking
I feel like I'm speaking with my therapist. Libba Bray
speaking
There is a part for everyone. And if they don't want a speaking part, they can be on the set crew. Kathy Deepe
speaking-up democracy principles
So now is the time, more than ever, for those who truly value all the principles of democracy, especially including dissent, to be the most forceful in speaking up, standing up and speaking out. Jim Hightower
speaking-well names grace
In the greatest difficulties, in the heaviest trials, in the deepest poverty and necessities, He has never failed me; but because I was enabled by His grace to trust Him He has always appeared for my help. I delight in speaking well of His name. George Muller
speaking start stuff
Sometimes, when we're together, we start just speaking pidgin and stuff like that and that's good, too. Itula Mili
speaking-well literature wells
If you make yourself understood, you're always speaking well. Moliere
speaking
Chemically speaking or biologically, we research things, but we don't know half of them. We only know our half of it - symbolically - and we don't know ourselves more than half. Yoko Ono
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
trouble mercy heavy
These heavy troubles are heralds of weighty mercies. Charles Spurgeon
trouble novel incomplete
There are things the story must have or else look incomplete. And these will almost automatically present themselves. When they don't, you are in trouble and then the novel stops. Chinua Achebe
trouble failure-of-leadership nigeria
The trouble with Nigeria is simply and squarely a failure of leadership, Chinua Achebe
trouble bloodshed hard
I labored hard to avoid trouble and bloodshed. Chief Joseph
trouble ifs
If you are a friend of somebody and that friend is in trouble, you don't just drop them. David Tang
trouble my-family bigs
If not for my family, I would have been in big trouble. Chad Everett
trouble crosses
Usually one gets a heavier cross when one attempts to get rid of an old one. Edith Stein
trouble economy free-market
The trouble with a free market economy is that it requires so many policemen to make it work. Dean Acheson
trouble reason authority
As soon as we abandon our reason and are content to rely on authority, there is no end to our troubles. Bertrand Russell
until worked
Until 1998, I worked in marketing at ASB bank. I loved it. Jonah Lomu
until
Divorce was illegal in Chile up until 2005 or so. Hector Tobar
until
We're going to look. We'll always look until we get that solved. Jerry Angelo
until
We're going to keep doing it until (the problem) disappears. Ed Troyer
until wait
Wait until you see what we have planned. Ruth Miller
until
I didn't have an exhibition anywhere until I was 30. My first exhibition was at 30, and then for my first show in America, I'm 50. It's kind of all right: I'm just a slow burner. Tracey Emin
until
We must not only strike the iron while it is hot, we must strike it until it is hot. Tom Sharpe
until
I started with the guitar around 12 years old but didn't learn the banjo until I was about 18 or 19. Elle King
until
She's about 40 pounds. She just sits there until I get annoyed. Miles Austin