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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
australia giving community
South Australia was the first community to give the secret ballot for political elections. Catherine Helen Spence
australia begin commitment continue history proud year
We are proud of our 40 year history in Australia and our commitment in the 1960s to begin manufacturing in Australia which we continue here today. Marketing Manager
australia data lower markets note per pleased recent run seen strong
We are pleased to note that the recent run of strong data in Australia has seen markets lower that probability to only about 15 per cent. Bill Evans
australia aware council cricket
We are at loggerheads with Australia and the International Cricket Council is aware of it. Gerald Majola
australia spending education-spending
Australia must prioritise education spending. It is not a question of whether or not we have the money, it is a question of how we choose to spend it. Bob Brown
australia laughing desire
I read the Phantom comics when I was in Australia shooting 'Dead Calm'' and when one of the crew told me that there were plans for a movie, I went for it. That was in 1987 and I told (producer) Graham Burke I was going to be the Phantom. We had a laugh about that recently because you usually get what you deserve, not what you desire, and that is especially true in Hollywood! Billy Zane
australian guy meant
What this Australian guy meant when he said I was a Googlewhack, Dave Gorman
australian close easing fed interest investors likely monetary policy quite rates renewed shifting starting toward widening wonder
U.S. interest rates are pretty close to the top. By year- end it is quite likely the Fed will be shifting toward easing monetary policy and investors will be starting to wonder about a renewed widening in the Australian and U.S. interest-rate gap. Shane Oliver
australia people nicknames
In Australia, everyone gets a nickname and people started calling me "Izzy" and I hated it so I just adopted Bella. Bella Heathcote
camps chad ensuring government primary refugee reminded responsibility security
We reminded the government of Chad that it has the primary responsibility for ensuring the security of refugee camps on its territory. Ron Redmond
camps community happy head hopefully improve next summer supported work year
We're going to head off to some big camps and tournaments this summer and get a lot of work in at the gym. We're very happy that the community supported us the way they did this year. Hopefully we'll come back next year and improve upon what we've established this season. Lamont McCann
camps cultural culture good hated job kids knows korean relate
When I made him go to culture camps, he hated it. And today, that's why he does such a good job at the Korean cultural camps (where he's an aide) because he can relate to the kids who don't want to be there. He knows what's in their hearts. Deborah Dawson
camps full goes life loaded seldom
She had the loaded handbag of someone who camps out and seldom goes home, or who imagines life must be full of emergencies. Mavis Gallant
camps improve large pay price refinement strengthen talents thus
Men, by associating in large masses, as in camps and cities, improve their talents but impair their virtues; and strengthen their minds, but weaken their morals; thus a retrocession in the one, is too often the price they pay for a refinement of the Charles Caleb
camps coal covers dust laws mud people protect roads shaking situation talked
The people I've talked to say the situation in the coal camps is getting worse. Blasts are shaking their houses, and dust and mud covers the roads and everything. There is nothing preventative about the new laws they passed. It was just an after-the-fact thing. It does nothing to protect the people. Larry Bush
camps drove finally group kinda left people three
Sen. Brownback went off to one direction. I drove into another direction. Another group went into another direction. We went up and down the camps and just kinda left people -- and finally got alone. Then in three of the camps, there were no minders with us, M. Wolfe
camps cells exile fear finally freedom leaders oppressed people prison stand torture until
There are nations, where people live in captivity, fear and silence. I believe, one day from prison camps and torture cells and from exile the leaders of freedom will emerge. The world should stand with those oppressed people until the day of their freedom finally arrives. Tsakhiagiin Elbegdorj
camps clowning clowns elevator none subway taken war
I've taken clowns into the war in Bosnia, the refugee camps of Kosovo, and none of those are any more important than clowning in a subway or an elevator or just walking down the street. Patch Adams
events bigs made
I've never made up events, but I've always been a big exaggerator. It's written on my humorist license that I'm allowed to do that. David Sedaris
events hard ourselves pushing strengthen week
We still need to strengthen ourselves in the sprints. We're pushing hard in those events this week in practice. Marilyn Fitzgerald
events great handled last played
We're in a great place to win. Everyone is gunning for us. We played really well in the last two events and for the most part, when one of us wasn't hot, the other did well. When we put it together, we really handled the teams. Todd Rogers
events president serious taking
Where is the president when such serious events are taking place? Jacques Chirac
events individual seven swim tired west won
We actually didn't swim very well tonight. West Chester won seven individual events out of nine. We were just tired and not as up for it. Mike Schnur
events phrases sometimes
Sometimes a single phrase of testimony can set events in motion that affect someone's life for eternity. Dieter F. Uchtdorf
events shapes courses
A single event can shape our lives or change the course of history. Deepak Chopra
events different journalism
A journalist is basically a chronicler, not an interpreter of events. Where else in society do you have the license to eavesdrop on so many different conversations as you have in journalism? Where else can you delve into the life of our times? Bill Moyers
events process
Change is not an event, its a process. Cheryl James
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
known nonlinear terms
There are challenges in terms of the measurement of VAR for what are known as nonlinear derivatives, where things like gamma and vega are important dimensions of the risk. John Hull
known throughout true
Throughout the ages, they are known as wise, who weep, remembering the True One. O. Singh
known
The dead are often known to eat 27 and 53 David Almond
known phenomena physicists quantum
With the exception of gravitation and radioactivity, all of the phenomena known to physicists and chemists in 1911 have their ultimate explanation in the laws of quantum electrodynamics. Richard P. Feynman
known loves man opens platform speak spends time
My greatest platform is not with all my degrees, everything else, it's not all my books, everything. It's that I'm known as a man who loves his wife and spends time with his children. That opens more; I speak as a daddy. Josh McDowell
known square
This will not be known as the Times Square of the West, ... Times Square will be known as the l.a. live of the East. Alex Padilla
known
Once a thing is known,it can't be UNknown. Chris Crutcher
known people
If you are well known at something else, you get points for doing stuff which lots of other people do, and much more, and they don't get any points at all. You get over-praised, over-credited. Tom Stoppard
known putting shooting
Shooting my scenes, I hadn't really even known what I was putting in his medicine, Roger Bart
mega
I don't dream to be like mega crazy rich. will.i.am
mega fortunate
I'm really fortunate that I've had some mega hits. Juice Newton
megalomaniacs
Im the shyest megalomaniac youre ever likely to meet. Kate Bush
offering flames wind
Without the Spirit of God we can do nothing. We are as ships without wind or chariots without steeds. Like branches without sap, we are withered. Like coals without fire, we are useless. As an offering without the sacrificial flame, we are unaccepted. Charles Spurgeon
offering errors judging
Save me from the error of judging a church by its size, popularity or the amount of its yearly offerings. Aiden Wilson Tozer
offering giving offering-to-god
We ought not to be looking for a place to hide, but a place to give ourselves as an offering to God. Aiden Wilson Tozer
offering care return
By offering individuals ownership and control of their health care coverage, we return control to the patients; and that is exactly where it should be. Chris Chocola
offering media ideas
Being overseas at the time it all kind of happened was perfect because I had no idea that it was going to attract so much media attention and provoke these lovely people calling in and offering up their opinions and advice. Cathy Freeman
offering tickets
We started by offering tickets to evacuees in the Starkville motels. We thought we would give out about 200 or so. Larry Templeton
offering yankees guy
One of the best things about being a Yankee is that you have guys like Whitey Ford, Phil Rizzuto, Ron Guidry and Reggie Jackson wandering around the locker room offering you advice. Derek Jeter
offering perfect culture
No place is perfect, but I admire Oahu for its offering of the tropical and the urban, and then its Asian-inflected culture and cuisines. Chang-Rae Lee
offering order television
If we were built, what were we built for? ... Why do we have this amazing collection of sinews, senses, and sensibilities? Were we really designed in order to recline on the couch, extending our wrists perpendicular to the floor so we can flick through the television's offerings? Were we really designed in order to shop some more so the economy can grow some more? Or were we designed to experience the great epiphanies that come from contact with each other and with the natural world? Bill McKibben
setting work
When I work on a novel, I usually have one character and a setting in mind. Kevin Henkes
setting various
There are various interpretations of the new law. It is setting us back. Sam Aiona
setting whatever whether
She's our unquestioned leader. She does so much, whatever we need, whether it's points, rebounds, assists, setting up plays. She does it all. Mike Harris
setting unable women
In the Sixties, fashion was about liberation. It was about setting women free; it wasn't about being unable to walk. Veruschka von Lehndorff
setting
I don't think it's so much of a disadvantage setting up from scratch. David Leslie
setting
I have begun, with my colleagues, setting up a new party, Ariel Sharon
setting team win
I'd been setting up my team all night, ... I'm going to win the game. That's what I do. . . . They didn't say it was going to be easy. Gilbert Arenas
setting
We've got the possibility of setting things right, Ruby Dee
setting talking teenagers
We've got two teenagers we're talking to right now, and one of them has confessed to setting the fire. Yvonne Martinez
southern desire pieces
The Northern onslaught upon slavery was no more than a piece of specious humbug designed to conceal its desire for economic control of the Southern states. Charles Dickens
southern said southerner
A true Southerner will never say in 2-3 words what can better be said in 10-12. Charles Kuralt
southern election certain
The secession of the Southern States, individually or in the aggregate, was the certain consequence of Mr. Lincoln's election. Belle Boyd
southern comfort world
I can't see this world unless I go/ outside my southern comfort zone. Brad Paisley
southern heritage dialect
I'm most comfortable with the Southern dialects, really. It's easy, for example, for me to do Irish because we've got Irish heritage where I come from. Brad Pitt
southern gentleman southern-gentleman
I'm a southern gentleman. Jamie Foxx
southern flying towns
Been on what I call my Flying Saucer Tour--appearing in small Southern towns--in front of handfuls of hillbillies. Bill Hicks
southern
We really have no idea what is going on now in southern China. Guan Yi
southern
Many, many of them are from southern Louisiana. Samantha Bingham
sports play interesting
It is interesting that Hindus, when they speak of the creation of the universe do not call it the work of God, they call it the play of God, the Vishnu lila, lila meaning play. And they look upon the whole manifestation of all the universes as a play, as a sport, as a kind of dance — lila perhaps being somewhat related to our word lilt Alan Watts
sports song thinking
I'm delighted about the track's success in the sports world, but the frustrating thing is, I don't think I got rich on it. The labels and publishers did very cheap deals on our songs. Alan Parsons
sports careers race
So in fact the only thing you can judge in this sport its the longterm. You can judge a career or a season, but not one race. Alain Prost
sports squash drivers
I was looking at the history of the sport and I couldn't understand why there have been so many good South American drivers, especially Brazilians. Alain Prost
sports winning thinking
When you win a race like this the feeling is very, very good. There have been times when I have been flat-out to finish sixth, but you can't see that from the outside. In 1980 I finished three or four times in seventh place. I pushed like mad, yet everyone was gathered around the winner and they were thinking that I was just trundling around. But that's motor racing. So in fact the only thing you can judge in this sport is the long term. You can judge a career or a season, but not one race. Alain Prost
sports thinking throwing
I don't think the discus will ever attract any interest until they let us start throwing them at one another. Al Oerter
sports team hate
I think the Cowboys are one of only two teams in all of sports that engender love and hate to that extreme. The other is the Yankees. You love the Yankees or you hate the Yankees. Al Michaels
sports vanity play
It's the bane of both the news and sports businesses, both electronic and print - 'You heard it here first!' Who cares? That's nothing but a vanity play. If it's not right, it's garbage. Al Michaels
sports believe miracle
Do you believe in miracles? Al Michaels
training felt
I loved being back out on the pitch. Although I have not been in full training, I felt pretty good. David Ginola
training stardom
I've been in training for stardom. Bernie Mac
training mind taught
I didn't mind basic training. It taught me that something that seems impossible at the start can be achieved. Arnold Schwarzenegger
training adore hard
I simply adore the exhaustion that comes with training hard. Deena Kastor
training boeing film
I always liked show biz and got to make a few training films at Boeing. Bill Nye
training mind spirit
The word liberal distinguishes whatever nourishes the mind and spirit from the training which is merely practical or professional or from the trivialities which are no training at all. Alan K. Simpson
training java degrees
I fear - as far as I can tell - that most undergraduate degrees in computer science these days are basically Java vocational training. Alan Kay
training benefits enough
You benefit from getting in enough volume at the beginning of your training. Bernard Lagat
training age trying
We've been trying to sell cyclists of all ages and abilities on very detailed and demanding education and training programs designed to make them more like motorists. Bicyclists have shown they don't want this. What cyclists repeatedly tell us they do want is more safe places to ride, and it is time we listened to that message. Bill Wilkinson