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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
apples age rama
The other major kind of computer is the "Apple," which I do not recommend, because it is a wuss-o-rama New-Age computer you basically just plug in and use. Dave Barry
apples ipods people
If Apple ever lowers the iPod's price and develops Windows software for it, watch out: the invasion of the iPod people will surely begin in earnest. David Pogue
apples meals looks
I love to eat an apple after a meal, just to cleanse my teeth - they always look polished afterwards. Catherine Zeta-Jones
apple difficult jobs period periods positive steve trajectory
The period when Steve Jobs was not there was one of the most difficult periods in the company's history. When he returned, he set Apple back on a positive trajectory again. Rakesh Khurana
apple hard hold lead minutes played today tough trying
We are a first-half team. ... Trying to hold a lead for 55 minutes is tough to do. We played hard today and so did Apple Valley. Ben Smith
apple closely java reason sun worked
The reason for that is Sun and Apple haven't worked that closely on Java in the past. Steve Jobs
apples cheese easier eat raw
I always have apples and fruit in the house. It's easier to eat something healthy if it's within reach. I also have yogurt, cheese and crackers, and raw almonds. Martina McBride
apple daring good greatest jobs
One of the greatest things that Apple and Jobs were very good at doing was daring to do the very different thing. It's what I did with my cookbook, frankly. Nathan Myhrvold
apple building companies company name
When you think of a company building its brand, you automatically think of things like Apple or Sony?larger companies where the company's name is really the brand. When I say Kraft, you probably think of macaroni. Jessica Dyer
clear fact providing region rely send signal talking
We want to send a clear signal that the region can very much rely on the fact that we are not just talking about providing assistance, but that we really want to help, and will help, Gerhard Schroeder
clear cornered
Things get very clear when you're cornered. Chogyam Trungpa
clear love script turn unfolds
I love to see how a character unfolds off the page in a project. I don't always know how the character is going to turn out, even with the script being there. It's not always clear where that character is going to take me. Or where I will take them. Lorraine Toussaint
clearly economy employment fed influenced next potential reflection report surprise
The potential is that there could have been a surprise that could have influenced the Fed next Tuesday, and clearly that hasn't happened. But employment is a lagging indicator. So the report is not a reflection of where the economy is going, but where it's been. Douglas Altabef
clearly position remains stated
The position remains as we have clearly stated it on many occasions. Peter Varney
clear involved jim people sullivan
The people who were involved in this, it's still pretty clear in their minds. Jim Sullivan is one of the big ones. Erik Friedly
clear company growth vehicle view
The only company which is a clear growth vehicle in our view is Schering-Plough. Barbara Ryan
clear constant devotion inspirational lead loyalty overcome surely
Unswerving loyalty to duty, constant devotion to truth, and a clear consciencewill overcome every discouragement and surely lead the way to usefulness andhigh achievement. Grover Cleveland
clear egg freezing might offered patients rush service technology
We are pretty clear that egg freezing is a pretty experimental technology and should only be offered to patients in that context. We think there might be a rush to offer this service before it's completely reliable. Sean Tipton
concerned enter formal interest though work
Even though what I do does enter the market, it doesn't interest me. I am exclusively concerned with the formal qualities of my work. It is about the need and the right to self-expression. Louise Bourgeois
concerned people speaks understood voted yes
The people who voted yes understood the issue, and that is really what we are concerned about. I think it speaks for itself. Linda Johnson
concerned conference high internet level managers people risks stocks taking trade understanding
The people who own Internet stocks are taking on a very high level of risk. Myself and most of the other managers at the conference are concerned about people who own and trade those stocks not understanding the risks they're taking. Bill Nygren
concerned consumer couple days economy hurting interest investors oil outlook past rates rebound related seeing start stocks
We are seeing a pullback on stocks because many investors are concerned with the outlook for interest rates and with the economy at the start of 2006. The rebound in oil in the past couple of days is also hurting some stocks, especially the ones related to consumer spending, such as retailers. Subodh Kumar
concerned corporate credit fears happening inflation people
There are some fears about inflation but people are even more concerned about what's happening in the corporate credit market. Gerald Lucas
concerned issue
We're not going to make an issue of it. We're more concerned who we're playing, not where we're playing. Matt Durgin
concerned embraced special
We have a special site, a special location. We have a neighborhood that at first was concerned but now has embraced us for the most part. Donald Trump
concerned fences high kids school sword
We have some chain-link fences that are kind of high in back of the high school and we're concerned about kids getting hurt, so it's kind of a double-edged sword there. Todd Jaeger
concerned humans human-beings
I just see myself as a human being that's concerned about life. Charlie Haden
consumers energy high higher lost oil pay prices though
The persistence of high oil prices can't be lost on the Fed. Consumers have to pay for higher energy even though it's volatile. It is a real cost. David Joy
consumer positive strong
We are positive on stocks, especially those that are benefiting from very strong U.S. consumer demand. Gary Campbell
consumers expect general gentle happier housing market pickup recovery retail sales seeing stronger wealth
We are seeing a gentle recovery going on in retail sales at this stage, which I expect to get stronger going forward. The pickup in the housing market should have a general wealth effect, making consumers happier to go out and spend. James Carrick
consumer continued corporate economy slowing spending
There are continued uncertainties, ... The U.S. economy is slowing and commensurate with that is slowing consumer spending and corporate spending. Alan Ackerman
consumer growth income retail robust signs source spending suggesting wage
There are some encouraging signs in retail sales, but if you look at what the source of consumer spending is, it's really income growth, and wage growth has been lackluster, suggesting the consumer will not be robust going forward. Scott Brown
consumer education impact insurance life provide rather unbiased
We want to provide unfiltered and unbiased consumer education about the impact of what life insurance does, rather than how it works. Bob Brown
consumers huge positive revision wages
While many will be disappointed that we will not necessarily see huge upward revisions to payrolls ... a significant upward revision to wages would also be a positive development, as it suggests that consumers have more firepower than we thought. Steve Stanley
consumers customer department issues resolve seem service telephone
We've become a customer service department for some of these companies. So many consumers can't seem to resolve their issues with telephone companies. Janet Jenkins
consumers tried
We've always tried to give consumers what they want, not what we feel they need, Michael Gallelli
features hard pale perfectly somewhat
I am very benign-looking. I'm somewhat like a golden retriever: It's not hard to look at me. I'm perfectly fine. It's not like things jut out and make you nervous. But the lovely thing about being so pale and having such pasty features is that I can look like pretty much anything, which is nice. Elizabeth Mitchell
features finally months several
We've been indicated for several months now that these features would develop, and they have finally arrived. Gerald Bell
features house invited people public trophy wondrous
We didn't want a trophy home. We wanted people to be invited into the house to see all the wondrous things, features that the public doesn't get to see. Ed Warner
features lead love series street worker
The 'Love Undercover' series features two cops, a street rat, and a construction worker as the lead heroes. Lori Foster
features luxurious
Rawness and refinement are not opposite ends of a luxurious spectrum... they are two complementary features with which to populate a luxe environment. Kelly Wearstler
features feed few items sure
On mobile, make sure Facebook's app can know where you are. That not only makes features like Nearby Friends possible but also makes your feed have a few items from your location. Robert Scoble
features science
One of the distinguishing features of anything that aspires to the name of science is the reproducibility of experimental results. Matthew Stewart
features filing
Ms. Willey features very prominently in our filing today. Donovan Campbell
features people
There are features that African Americans have that are similar! There are features that white people have that are similar! Features that Hispanic people have that are similar! Don Lemon
interested start sure talking
We want to start talking (soon) and make sure we let them know we want them. They've let us know they're very interested in talking. Dennis Morgigno
interested
We are at capacity. We are interested in getting new equipment. John Parsons
interested quick safe using
We're interested in using it if the waivers are in place and it's a safe alternative, ... This is not a quick fix. It could be a multi-year process. Valerie Miller
interested spend time uses
We're interested in knowing, ... how much each one of you uses the Internet. How much time do you spend on it? Judy Woodruff
interested parties solution
We?re in discussions with other interested parties ... to see what kind of solution we could come up with. Valerie Cunningham
interested plays son
We have a son that plays for one of the schools. I'm very interested in men's basketball. Charles Clarke
interested whether
whether or not I'd be interested is a whole other issue. Rod Paige
interested movies
When I was making my first films, I was very interested in Hollywood B movies. Park Chan-wook
interested
We're so interested in it because it's different for everyone. Joyce Brothers
lowest man
When I was in London at NBC, I was the lowest man on the totem pole. I would go to diplomatic receptions to meet people. Leslie Cockburn
lowest school
When you're a cash-strapped school system, you're going to go to the lowest bidder. The lowest bidders are the ones who are going to export. Jim Puckett
lowest newspaper
A newspaper is the lowest thing there is. Richard Daley
lowest quarters second
Traditionally the first and second quarters have the lowest losses. Dave Dasgupta
lowest possibly round shoot tomorrow
Tomorrow I've got to do it again, I have to shoot the lowest round I possibly can. Vijay Singh
lowest morale point since
Morale is at the lowest point since I've been here. David Davis
lowest sort
My father was highbrow: writing long biographies of Dante and stuff like that. Ghostwriting sportsman memoirs? That was sort of the lowest of the low. David Lagercrantz
lowest proudest rookie thrown
He's been thrown into the fire. It was the lowest of the lows. In my rookie year, he was getting booed off the field. Of anybody, I'm proudest of Matt. Steve Hutchinson
lowest obviously
A common price isn't the lowest price. It will most obviously be the highest price. Alexey Miller
marketing phrases idiot
That pompous phrase (graphic novel) was thought up by some idiot in the marketing department of DC. I prefer to call them Big Expensive Comics. Alan Moore
marketing advertising timing
Strategy and timing are the Himalayas of marketing. Everything else is the Catskills. Al Ries
marketing company ultimate
Marketing is what a company is in business to do. Marketing is a company's ultimate objective. Al Ries
marketing mind building
Marketing is not selling. Marketing is building a brand in the mind of the prospect. Al Ries
marketing cows looks
A branding program should be designed to differentiate your cow from all the other cattle on the range. Even if all the cattle on the range look pretty much alike. Al Ries
marketing world needs
All you need is the best product in the world, the most efficient production in the world and global marketing. Akio Morita
market
We still like the equities market and think the S&P 500 could potentially go through 1300 this week. Henry McVey
marketing advertising products
Marketing is what you do when your product is no good. Edwin Land
marketing coaching good-coaches
I was a pretty good coach and working with marketing was like coaching. Bernard Ebbers
possible-and-impossible people want
I only want people around me who can do the impossible. Elizabeth Arden
possible-change open-minded authority
Being yielded to God's authority keeps us pliable and open-minded to a possible change of plans. Beth Moore
possible situation
We're going to look at every possible situation at that position. Always have, always will. We've got to get it right. We know that. Jerry Angelo
possible
We're going to be very transparent and let them know any possible thing that happened. Robert Henderson
possible
make it possible -- more possible -- to do our job. George H. W. Bush
possible rule
My one big rule for the over-40s is don't try to dress like an 18-year-old. It's possible to be 'on-trend' when you're older - you just have to look for the right stuff. You don't have to spend a fortune, either. Twiggy
possible raised strongest
She raised (the case) in the strongest possible terms." () Sean McCormack
possible-love inches ashamed
I drive around the streets an inch away from weeping, ashamed of my sentimentality and possible love. Charles Bukowski
possible
I don't want to be just an average guy. I want to do whatever possible to win a lot of games. I'm a competitor. Felix Hernandez
prices stocks turns volume
When volume drops off, prices settle down. Volume is the force that turns stocks higher. Louis Navellier
price-of-freedom vigilance stills
The price of freedom is still, and always will be, eternal vigilance. Margaret Thatcher
price stay structural
We have said that this is a structural issue, not a short-term factor, and the price is going to stay the same, Rafael Ramirez
price question successful
We know we'll be successful with this operation. The only question is the price we'll pay. Stephen Davis
priceless
Price. You're priceless. Bret Easton Ellis
price-of-success paid paid-in-full
The price of success must be paid in full, in advance. Brian Tracy
prices
One of the prices that we pay for integration was the disintegration of the black community. Ed Smith
price-tag vision tag
The grander the vision the greater the price tag. Bill Hybels
price reasonable resonate sounds
The price sounds reasonable and should resonate with consumers, Michael Gartenberg
segments
There are so many segments that are appropriate today. Lee Mendelson
segment technology year
I think what you need to do in the technology segment between now and the end of the year is own the leaders, Francis Gannon
segment
A play-it-safe-redesign of the Camry was out of the question. The market, and the segment in which Camry competes, is just too competitive. Don Esmond
segment survive
The mid-sized SUV segment is probably not going to grow, but will become even more fragmented. To survive in the segment, automakers are going to have to make a real difference. Joe Eberhardt
segment
It's one of the, if not the most competitive segments. You have high-volume brands, and a lot of their entries in that segment are flagship models. Tom Libby
sells
Everybody has to sell out at some point to make a living. Dennis Miller
selling assets process
I have some assets that over time will be worth something. I've been in the process of selling others. Bernard Ebbers
sell series
We've been able to sell more series than we had planned, but they take capital. Craig Parsons
selling soon supplies
We're getting supplies of all of these, and we're selling out as soon as we get them, Brian Lucas
selling-more goal priorities
Selling more of what you sell has nothing to do with what you sell. It has everything to do with your prospect's wants, needs, fears, goals, values and priorities. Don Cooper
selling encyclopedia right-now
Elvis is my religion. But for him, I'd be selling encyclopedias right now. Bruce Springsteen
sells
Never buy a stock immediately after a substantial rise or sell one immediately after a substantial drop. Benjamin Graham
sell
Look, as long as we can make records and sell enough so we can do some shows, that's all I want. You know what? I just want to play guitar and be in a band. Same as I always did. Chrissie Hynde
selling
It's like recycling: selling old clothes to help make new ones. Erin O'Connor