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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics.
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online.
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services.
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts.
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters.
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here,
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof.
certain diffidence valour
Discretion has been termed the better part of valour, and it is more certain, that diffidence is the better part of knowledge. Charles Caleb Colton
certain one-thing
For whatever the future holds, one thing is certain... It just won't be the same. Alan Moore
certainty evidence deals
Science deals in evidence and uncertainty. Religion deals in certainty without evidence. David Milne
certain head movies
I think there's certain things that I know in my head that I enjoy: action movies. Lucas Till
certain filmmaker individual observed point rather
I feel like I've been observed as an individual more than a gay person, or as a filmmaker with a certain point of view rather than a lesbian filmmaker with a gay point of view. Lisa Cholodenko
certainty forms global humans life nuclear producing soon stand threat tinker verge vintage war
If there is anything more frightening than the threat of global nuclear war, it is the certainty that humans not only stand on the verge of producing new life forms but may soon be able to tinker with them as if they were vintage convertibles or bonsai trees. Michael Specter
certainly continued obviously president relationship white
I certainly know that this relationship could not have continued the way it did, when I was at the Pentagon and the president was obviously at the White House, without Betty. Monica Lewinsky
certainly chinese doctors filtered following four gotten government individual latest listed manual medical ordinary people perceive profession raid shows step until version
Until about four years ago, the Chinese medical profession was still following a version of the diagnostic manual that still listed homosexuality as an illness. That has also changed, but that may not have filtered down into how individual doctors or just ordinary people perceive it. Things have certainly gotten better, though, but this latest raid shows that the government can still step back, as well as forward.
certainty clearly johnson objective offer potential providing superior today upside value
We are providing Guidant shareholders with certainty of completion, significant upside potential and substantially more value today than the Johnson & Johnson transaction. By any objective measure, our offer is clearly superior to Johnson & Johnson.
department proud
We are proud to be working with the Department of Corrections for our 20th year.
department offense pitching stronger weaker work
We are probably a little stronger in the pitching department and probably a little weaker in the offense department. I don't know how that's going to work out. Phil Garner
department problem send
We have no problem with any other department in the county. Normally, we send a request, we get a response.
department equipment fear level people respect scared teach training trust
What the training did was teach me to trust my equipment and trust the other people that I'm working with, ... The firefighters will say, 'You should always be scared. If you're not scared then you should get out of the department because that's when you get hurt.' You have to have a level of fear and a level of respect for what it is you're doing, and if not, I think it breads a level of complacency, which is very dangerous. Joaquin Phoenix
department group kingdom though united
The United Kingdom has traditionally been a very small market, and even though you had such a creative group of designers, they represented a risk to department stores. Natalie Massenet
department justice people serving whether
whether the Justice Department is serving the American people as it should. Orrin Hatch
department security state violated whether
whether or not he violated the Department of State security standards. Richard Boucher
department joe kennedy print roy sent teddy worked
When I was in Congress, I worked with Joe Kennedy to rename the Justice Department for Bobby, and when I retired, Teddy Kennedy sent me this Roy Lichtenstein print of his brother, inscribed: 'Bobby would have been proud of you.' Joe Scarborough
department district excited granite kids police priorities safety school wonderful
We're so excited to have him. The wonderful part about the Granite School District Police Department is their priorities, and only priorities . . . are the safety of kids and patrons in the district.
disasters environmental health whether
The world has been experiencing a whole pattern of auto-destruction, whether in environmental disasters like Chernobyl or health disasters like AIDS.
disaster broads foreign-policy
The Obama foreign policy, in broad strokes, has been a disaster. Charles Krauthammer
disaster capture ideals
It is not a disaster to be unable to capture your ideal, but it is a disaster to have no ideal to capture. Benjamin E. Mays
disaster seen
We have seen 2004 and 2005 as the years of disaster, Jan Egeland
disaster fine godzilla good knocking loved monster movies remember time
When I was little I used to see Godzilla all the time on TV, ... I just remember him knocking things over, which was fine with me. I loved monster movies and disaster movies, and this was a good combination. Matthew Broderick
disaster economic good praying rain sitting top
We're sitting on top of what very well could be an economic disaster. A lot of praying for a good soaking rain is all that can be done.
disaster expensive information natural
What this information shows, I think, is this was the most expensive natural disaster in American history.
disaster emergency example fact handle microcosm moved quickly save situation
Weyauwega is a microcosm of how to handle a disaster. This was an example of an emergency situation that would have been a disaster save for the fact we moved quickly and, I believe, correctly. Tommy Thompson
disaster identify situations types
We're simulating a real-life disaster to identify the types of situations we could potentially face.
government people should
People shouldn't be afraid of their government. Governments should be afraid of their people.
government giving enemy
In the time of Mrs Thatcher the church, to give it its due, spoke out and was an enemy of the Conservative government. Alan Green
government favors corruption
In general, corruption tends to exist whenever governments have favors to extend, or something to sell. Alan Greenspan
government purpose regulators
The guiding purpose of the government regulator is to prevent rather than to create something.
government support political
Stripped of its academic jargon, the welfare state is nothing more than a mechanism by which governments confiscate the wealth of the productive members of a society to support a wide variety of welfare schemes. A substantial part of the confiscation is effected by taxation. But the welfare statists were quick to recognize that if they wished to retain political power, the amount of taxation had to be limited and they had to resort to programs of massive deficit spending, i.e., they had to borrow money,by issuing government bonds, to finance welfare expenditures on a large scale.
government self credit
We are in the midst of a once-in-a-century credit tsunami. Central banks and governments are being required to take unprecedented measures. Those of us who have looked to the self-interest of lending institutions to protect shareholders' equity are in a state of shocked disbelief.
government giving needs
We need an amendment that gives us the right to vote protected by the federal government and the Constitution. Al Sharpton
government america united-states
If we have any problems, it's always with the government of the United States. Akbar Hashemi Rafsanjani
government opportunity work
We want the opportunity to work with the government on this.
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
lessons management investment
A Lesson on Elementary, Worldly Wisdom As It Relates To Investment Management & Business Charlie Munger
lessons hard-lessons hard
The more hard lessons you can learn vicariously rather than through your own hard experience, the better.
planning chill daydreaming
Nothing is my guiltiest pleasure. I love it. I love doing it. I love planning to do it, I love loafing and pottering and chilling and daydreaming. David Morrissey
planning spontaneous be-spontaneous
You must plan to be spontaneous. David Hockney
planning
Success is the residue of planning. Benjamin Franklin
planning asks
We must ask where we are and whither we are tending. Abraham Lincoln
planning wait
The planning is complicated. ... But we can't wait any longer.
planning ifs
If you can visualize it, you can actualize it. Dennis Conner
planning played role
Sebastian played a big role in our planning for the World Cup.
planning products wild
We are planning some more wild products in 2006. Edward Zander
planning thanksgiving
We are planning on having Thanksgiving in Washington, Patrick Leahy
principles republican loses
[Republicans] swapped principle for power. They ended up with neither. They deserved to lose.
principles world down-and
Nobody has the time to sit down and explain the first world from first principles. Chris Cleave
principles compromise
I don't compromise my principles for politics. Chris Christie
principles degrees cost
The first principle of the market economy is that it is comprised of many small buyers and sellers, which implies a substantial degree of equity. Another fundamental market principle is that costs are internalized in the producer's price. David Korten
principles economics economy
Our global economy is out of control and performing contrary to basic principles of market economics.
principles way prosperity
I studied what principles under-laid peace and prosperity and concluded the only way to achieve societal well-being was through a system of economic freedom. Charles Koch
principles income states
Many states rely on sales tax as their principle source of revenue and do not have a State income tax. Bill Jenkins
principles filters needs
Most electronic equipment uses the principle of amplification. You need filters, modulators and mixing equipment which have gain stages. By piling these components up, I was able to work without any sound generators and I made several pieces in that manner. David Tudor
principles investigation stomach
Every investigation which is guided by principles of Nature fixes its ultimate aim entirely on gratifying the stomach. Athenaeus
providence mark ifs
We must mark God's providence leading us; and if providence tarries, tarry till providence comes Charles Spurgeon
provides recognize turn turned vehicle
When you turn it on, it will recognize that that vehicle turned it on - date, time, everything. It essentially provides accountability.
provide strongly
I strongly disapprove of torture and have never and would never provide assistance in its process. Martin Seligman
provide run
We're going to run some new plays, and we think they're going to provide us some more momentum.
provide services
We're being called on to provide services we don't have,
providers step ultimately
Ultimately there could be two providers in Portsmouth, ... one step at a time.
provide town type
She said she had no idea which town she in. Fortunately we were able to provide this type of intervention before a catastrophe occurred.
provide students
We're able to provide a lot of opportunity. These are the things that students see the most.
provided statements
Many of the statements (appeared) to have been provided to her.
resources
We're getting a lot of good, technological resources we can use. David Taylor
resources
There are only so many resources that can be allocated to these programs.
resources minutes
Time is your most precious resource; make every minute count. Brian Tracy
resources using
I'm using all my resources to help me with that and I feel the sky is the limit for me. William Green
resources sue
We don't have the resources to sue everybody.
resources planets
The planets resources are rare; we must consume more ethically and equitably. Alain Ducasse
resources supporters
There are so many more resources in Harrisburg. I have a boatload of supporters there.
resources supplies sure trying
We're trying to make sure that the residents that are out there have the supplies and resources that they need, and that they are safe.
resources
You have more resources than you can probably imagine.
thinking hiking feet-and-walking
If I could not walk far and fast, I think I should just explode and perish. Charles Dickens
thinking vanity
None of us are so much praised or censured as we think.
thinking two glory
There are two things which ought to teach us to think but meanly of human glory; the very best have had their calumniators, the very worst their panegyrists.
thinking enemy frankness
He that openly tells, his friends all that he thinks of them, must expect that they will secretly tell his enemies much that they do not think of him.
thinking people remember
A thorough-paced antiquary not only remembers what all other people have thought proper to forget, but he also forgets what all other people think is proper to remember.
thinking daring finished
Those who have finished by making all others think with them, have usually been those who began by daring to think with themselves.
thinking mind wish
I never thought before, that there was a woman in the world who could affect me so much by saying so little. But don't be hard in your construction of me. You don't know what my state of mind towards you is. You don't know how you haunt and bewilder me. You don't know how the cursed carelessness that is over-officious in helping me at every other turning of my life WON'T help me here. You have struck it dead, I think, and I sometimes wish you had struck me dead along with it.
thinking greed words-of-wisdom
"As I think I told you once before," said I, "it is you who have been, in your greed and cunning, against all the world. It may be profitable to you to reflect, in future, that there never were greed and cunning in the world yet, that did not do too much, and overreach themselves. It is as certain as death."
thinking words-of-wisdom secret
Don't you think that any secret course is an unworthy one?