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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
army-and-navy bring roadblocks
We want the IDF (army) to bring back all the roadblocks in our area, Shaul Goldstein
arms larry leading machine nearly products rocker thank
We want to thank Larry Torres of T&D Machine Products in Carson City. They're the leading supplier of rocker arms for nearly everyone in racing. Steve Shaw
army years four
I spent four years in the United States Army between 1985 and 1989, and I certainly learned how to survive out in the woods. Chad Coleman
army childhood brain
Half my family was from the Imperial Japanese Navy, and the other half was U.S. Army, and I was raised on Army posts during my childhood, so I pretty much began my life with a split-brain sort of thing. Cary-Hiroyuki Tagawa
army four-horsemen-of-the-apocalypse wind
Army, Marriage, the Church, and Baking: the Four Horseman of the Apocalypse. Fermin Romero de Torres - The Shadow of the Wind. Carlos Ruiz Zafon
army college records
Our major universities are now stuck with an army of pedestrian, toadying careerists, Fifties types who wave around Sixties banners to conceal their record of ruthless, beaver-like tunneling to the top. Camille Paglia
army produce miniatures
An army is a miniature of the society which produces it. C. L. R. James
armed dawn dozens empower forces laws police throughout united
Throughout the United States, at the dawn of the Progressive era, dozens of laws and regulations were established to empower police officers, public-health officials, and even the armed forces to vaccinate at will, and, if necessary, at gunpoint. Michael Specter
arm billion bit boost change cut disposable felt income might personal shot spring tax
The personal income tax cut could be a boost of $50 billion to disposable income, and some of that could be felt when they actually change the tax withholding schedule, which could be in the spring or summer. Then there might be a little bit of rebate check, too. All of this might be a little more of short-term shot in the arm than the dividend tax cut. Joshua Feinman
athletic swim
I don't swim! That's like athletic. Chloe Sevigny
athletic atmosphere good learning positive program support
the positive learning atmosphere and very good support of the athletic program that Kirkwood offers. Jill Williams
athletics college gift perfect
The perfect going-away gift for a college student-athlete. A dictionary. Dave Anderson
athletic expect strongest
We are probably the most athletic and strongest team. Being that we are so athletic, we expect to go all the way. Steve Smithwick
athletic maximize team
We are a very athletic team and we're going to try to maximize our opportunities with our athleticism. Chris Vermeer
athletics best classroom mean playing strive succeed
We strive to do what is best for our student-athletes so they can succeed in the classroom and on the playing field. Athletics done the right way can mean so much to a university, like it has here at Colgate for many, many years. David Roach
athletic offer ready serve stand sugar willing
We stand ready and willing to serve the Sugar Bowl. We'll offer them all our athletic facilities. Skip Bertman
athletic choose either formula helps incredible side
If I walk up to a can of Red Bull, I'm thinking about Formula One; I'm thinking about incredible athletic performances. And it helps me choose that can over something else to either side of it. Nick Woodman
athletic bad basically guard hold left offensive people position says
When you tell people you're a left tackle, it basically says that you're the most athletic offensive lineman. To hold that position down, it's a sense of pride. You can get away with having a guard who's not as good. You can't get away with having a bad left tackle. Levi Jones
breaking company consumer designed financial food goods growth market plan poised profile ranks strategic terms vault
We are poised for breaking away from our competitors in the food industry, ... This strategic growth plan is designed to vault our company into the ranks of the world's renowned consumer goods companies, in terms of financial profile and market multiple. David Johnson
breaking coming fast gaining throwing
We started pressuring them and they started throwing turnovers. We were just fast breaking and started coming back and gaining some confidence. Mike Johnson
breaking confront crises iraq national preventing
We're in danger of breaking our army and preventing our national leaders from having the flexibility to confront not just Iraq and Afghanistan, but crises around the globe. Jack Reed
breaking deliver extended gives home older quite robust video
Older generations of Wi-Fi weren't quite robust enough to deliver video in the home without breaking up and losing packets and so forth. 5G Wi-Fi gives you extended reach, extended data rates, and more robust coverage. Henry Samueli
breaking fit maybe pitching work
We want him to keep pitching well, maybe work on his breaking ball. It just doesn't fit for us right now, but it will again. Buck Showalter
breaking catching close experience fly market news stock totally unique watching
Watching live sport, catching breaking news or the stock market close as you fly will be a totally new and unique experience in Australia, Kim Williams
breaking came caught chased front good grew help hill horse laughing north ranch stood took until yelling
We grew up on a ranch in North Dakota. Paige was really good at breaking horses. But one day this horse took off up a hill, and then it came charging down the hill bucking. Paige was yelling at me, 'Help me. Get in front of it. Get in front of it.' I just stood there laughing until he got bucked off. He was so mad, he chased me around the ranch all day, but he never caught me. Now that he's here, I am so proud, and I know we'll help each other all the time. Gerard Baker
breaking law
We're not anti-immigration. We're anti-illegal immigration. When you come illegally, you're a criminal. You're breaking the law. Jeff Hewitt
breaking coming credit good job kept knew outside players strengths
We knew what their strengths were and their outside players did a good job of breaking around our wings. It was a good hard-fought Mid-Penn game. They kept coming at us and the credit to them. Greg Clippinger
chance community
We want to take it to a community and give everyone a chance to come on board. Steve Wingfield
chance halfway chances-are
If you hear something you like, and you're halfway like the public, chances are they'll like it too. Chet Atkins
chance take-a-chance ifs
If you don't take a chance-you won't have a chance. Cale Yarborough
chance fun great looking riding role time
It was a fun film. I had a great time doing it. I was looking for a role just like that for my first movie role. I didn't want to have a starring role, because I wanted a chance to learn. I didn't want the whole thing riding on me. Luke Perry
chance form impossible lost seems time tried
Every time I start a new novel, it seems like an impossible undertaking. If I tried to do too much too quickly, I would get lost and feel overwhelmed. I have to go slow, and give things a chance to take form and grow. Louis Sachar
chances division everybody improving looking ownership teams throughout tries
The one thing we have in our division is everybody tries to get better. We've got ownership throughout the division where teams are looking to improve. . . . If you're not improving in our division, chances are you're not going to win. Mike Shanahan
chance digital global outlets physical power retail
The power of digital distribution over physical retail outlets is you have a chance to create a global audience. Chad Hurley
chance class difficult drop good kids potential school success teaching
The potential right now for success at that school is very, very high. Of the 30 kids in my class, about 10 are Hispanic. It's very difficult for me to look at those kids that I'm teaching now and know that statistically there's a good chance some of them will drop out of school. Lee Scott
chances enhance means necessary panic paris performance
The performance in Paris was unacceptable. We will do what is necessary to enhance our chances of doing well in the World Cup. If that means making changes, so be it, but we are not going into panic mode. Martyn Thomas
couple hands people
It was a good thing to have a couple of thousand people all rigid and frozen together, in the palm of one's hand. Charles Dickens
couple men hands
I am a neat hand at cookery, and I'll tell you what I knocked up for my Christmas-eve dinner in the Library Cart. I knocked up a beefsteak-pudding for one, with two kidneys, a dozen oysters, and a couple of mushrooms thrown in. It's a pudding to put a man in good humour with everything, except the two bottom buttons of his waistcoat. Charles Dickens
couple hands want
I don't want to permanently damage myself! On the other hand, a couple of days off the keyboard tends to make things somewhat better. Charles Stross
couple may terrible
I'm told that a couple of my Russian translations are just plain terrible, though, and there may be others. Charles Stross
couple years my-boyfriend
Over the last couple of years, I've really worked toward balancing my life out more, having a little bit more time with friends, family and my boyfriend. There was a period of time when they were way down the list. It was all about music and touring and if everything fell by the wayside, so be it. Alanis Morissette
couple majority adaptation
I increasingly fear that nothing good can come of almost any adaptation, and obviously that's sweeping. There are a couple of adaptations that are perhaps as good or better than the original work. But the vast majority of them are pointless. Alan Moore
couple guitar burritos
I played guitar. I've always considered myself an actor, but I wasn't making a living as an actor. So I was in a couple of folk groups that managed to keep me in underwear and burritos. Alan Arkin
couple moving done
There are times when I am directing, and there are a couple of moments I didn't get the way I wanted, but I know I still have other angles to shoot and I have to be done by noon; I move on. Alan Ball
couple believe next
I still believe Emmitt has enough left in the tank to be a productive back over the next couple of seasons. Al Michaels
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
lasts remember there-is-hope
Remember, to the last, that while there is life there is hope. Charles Dickens
lasts fool firsts
Ridicule is the first and last argument of a fool. Charles Simmons
lasts dubbing spokes
I have just returned from the dubbing studio where I spoke into a microphone as Severus Snape for absolutely the last time. Alan Rickman
last nine won
We've won nine of the last 11, so I like our chances. Eric DiBiase
last people ready year
We want to show that we're no joke. People thought last year was a fluke. We can make improvements from last year. We're ready to see what's out there. Andrew Palmer
lasts eloquent last-time
We looked at each other for the last time; nothing is as eloquent as nothing. David Mitchell
lasts records haircuts
You're only as good as your last record. David Sanborn
lasts female worship
The last western society to worship female powers was Minoan Crete. And significantly, that fell and did not rise again. Camille Paglia
lasts needs kind
I need some kind of... like... last minute, poorly-set-up deus ex machina!! Bryan Lee O'Malley
pitcher
You can't go out to the mound, hobbling and take a pitcher out with a cane. Casey Stengel
pitcher
Nobody ever had too many of them (pitchers). Casey Stengel
pitcher proverbs
The pitcher will go to the well once too often. English 14th Century Proverbs
pitchers variety
She has a variety of pitchers that make her successful. Dan Hogan
pitchers strike
Most pitchers have one pitch to strike out batters. Derek has three. Jeff Messer
pitchers ran shut year
We ran into two pitchers that year who shut us down. Augie Garrido
pitcher
We won't see a better pitcher all season. Bill Buscetto
pitchers state top
Right now I think we have two of the top pitchers in the state on our team. Kelly Ryan
pitchers playing
Only our pitchers have been playing well. We've been scratching and clawing for runs. We'll find a way to get it done any way we can, but we've been inconsistently offensively. Darin Erstad
reports talk useful willing
We're always willing to talk about how to make reports like this as useful as possible. Tony Fratto
reports science tragedy
Certainly, if these reports are true, it's a tragedy for science. Nigel Cameron
reports steps terms
What you have is an important set of steps in terms of these are high-temperature, high-pressure facilities. And that's if you have not had any damage, and we know from preliminary reports that's not the case. John Felmy
reports seen trying whether
We have seen these reports and we are trying to find out whether he has said these things. Shaharyar Khan
reports
There have been reports of higher-than-usual absenteeism at some locations. Gary Mickelson
reports
We've had firsthand reports that it's a mess. Mickey Loomis
reports vague
Vague injurious reports are no men's lies, but all men's carelesness. Arthur Helps
reports unless
Even if the reports are good, I'm still not going in unless I have to. Larry Jensen
reports scattered true
In Illinois, there are very scattered reports of true influenza. Susan Johnson
strikes
You're born with two strikes against you, so don't take a third one on your own. Connie Mack
strikes throw
We throw strikes and play defense, that's pretty much our philosophy. Dan Nobbs
strikes threw
I thought (Shaver) had big-league command. Everything was down in the zone. He threw 43 strikes in 58 pitches. Tom Pratt
strikes throwing
He was throwing strikes, that's the thing. You try to be patient, but if he's throwing strikes with it, you find yourself in the hole. Derek Jeter
strikes
Directing is like meeting a woman. You don't know her, but something strikes you, and then you just have to go into it. Maximilian Schell
strikes
We think that this strikes the right balance. John Hedgecoth
strikes deeper harder
The harder you strike it, the deeper it goes. John Ortberg
strikes ability remains
[He] alone is truly nonviolent who remains nonviolent even though he has the ability to strike. Mahatma Gandhi
strikes throws
He throws a lot of strikes and that's all we ask. Matt Magee
tall
She's a big girl. She's tall and very, very strong. She was very physical. Ashley Boehnel
taller teams worried
I'm always a little worried when we play teams that are taller than us. Kevin Estes
tallest waves
We all had a go and we probably surfed the tallest waves of our lives. Greg Long
tall
They're tall ... real tall. And real pretty. Adam Baker
tallest top
That's why they're top Division-I athletes. They get the fastest, quickest, tallest players. Eric Osmundson
tall
Even with 'stealth' it's still a tall pole, Tom Thomson
tall
Usually, I get hired because I`m tall. Peter Falk
tally-youngblood
I'm Tally Youngblood. Make me pretty." -Tally Youngblood Scott Westerfeld
tall-trees get-back
You'll get back to where you came from. William Golding
three four finished
In 1980 I finished three or four times in seventh place. Alain Prost
three balls easy
The three-ball is an easy shot if you're uncontested, but when they know you can shoot, it's a lot harder to get off. Chris Copeland
three essentials action
There are three essential factors in all human activity: spirit, materials, and action. Chiang Kai-shek
three kind i-can
I can find only three kinds of business in the Universe: mine, yours, and God's. Byron Katie
three england beats
When you beat Arsenal, they are a good three points. Bryan Robson
three
The other three have really made strides. They're consistently getting better. Bill Wright
three
We've already got three up on the board. Steve Alford
three moments hours
Preferred three hours quicker over one moment late. William Shakespeare
three kind persons
Before repeating something bad about another person, ask yourself these three questions: Is it true? Is it necessary for me to tell it? Is it kind to tell it? Charles L. Allen
throws youth
What the young one begs for, the grown-up throws away Russian Proverb
throws
When Ari throws a pitch, I know where it is going to go. Ashley Lewie
throws
This may be what throws us into recession. Maureen Allyn
throws
I know (Kinsey) would have been here. It's one of those things: He wasn't here on time, so he doesn't start. That throws Renaldo back in there. Dave Odom
throws trouble
It throws me in the toilet. I'm going to have a lot of trouble getting another picture. Carroll Ballard
throws
Very talented, I like the way he throws the football, Dan Hawkins