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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
cell-phone thrift unwanted
Old is unwanted. You don't find Thais going to the thrift store. They want new clothes. They want the newest cell phone. Alan Bishop
cells apples phones
Everyones always asking me when Apple will come out with a cell phone. My answer is, Probably never. David Pogue
cells littles triumph
Every cell is a triumph of natural selection, and we’re made of trillions of cells. Within us, is a little universe. Carl Sagan
cells brain return
Breaking up: It's so easy to return their possessions, but so hard to get our brain cells back. Cathy Guisewite
cells clear french-scientist infection later load primary seems
What seems to be clear to me is that after the primary infection most of the cells die indirectly, but at the later stage, when the viral load is very high, the virus kills a lot of cells directly. Luc Montagnier
cell lines people positive quickly research side specific
The positive side is it allows people to get cell lines made for specific diseases, do it quickly and to do research on it. Paul Sanberg
cell hearts minds phone younger
We're in a place where it's an important battleground for the hearts and minds of younger cell phone users. Jeffrey Nelson
cell final human legal step
where it's legal to do the final step ... the human cell nucleus transfer. Brigitte Boisselier
cells chemical design direct future ideal replace
When you think of all the things that are made from oil or in the chemical industry, if in the future we could find cells to replace most of those processes, the ideal way would be to do it by direct design. Craig Venter
found presence-of-god absolutes
True and absolute freedom is only found in the presence of God. Aiden Wilson Tozer
found frustrating
I never found it frustrating not speaking. David Selby
founders humans
The more we see the founders as humans the more we can understand them. David McCullough
found industry bits
It's changing a bit, but the thing in LA is everyone is either in the industry, or knows someone who is in the industry. So, they don't let on that they recognize you, that's what I've found out. Catherine Bell
found late post scandal whatsoever yesterday
The Post found out about this late yesterday afternoon. They had no inkling whatsoever a scandal was brewing. Howard Rubenstein
found good help jason jefferson job richard struggled
We struggled with Jason Kidd and Richard Jefferson but we found a way to help each other and I think we did a good job tonight. Mehmet Okur
found friendly offer ourselves quickly shocked together
We are making a friendly offer to Reynolds, ... We were shocked when we found out that Alcoa had made its offer and we assembled ourselves as quickly as we could to put together this proposal. Michael Lynch
foundation emotion reason
Emotion is the foundation of reason. David Brooks
foundation donation
I am the donation to the foundation. Baron Davis
normal
How can you be afraid of women?” “Those ain’t normal women. Dave Barry
normal being-a-woman taboo
All the things that are taboo are the things that are not normal, and all the things that are not normal are the things that are exclusively about physically being a woman. Caitlin Moran
normal shot today
We've all bowled at Cadillac, but today wasn't like the normal Cadillac. It was a very playable shot but just a little different. Scott Carpenter
normal played settled
We started off very poorly. But we know what we can do. We just settled down and played our normal game. Joe Johnson
normal particular produce quantities traces
Coproporphyrin in particular is widespread; traces are present in normal urine and also in yeast. In special cultures, yeast can be made to produce considerable quantities of coproporphyrin. Hans Fischer
normal persons
I had to bring myself back down to being a normal person again. Aidan Quinn
normal appetite wells
I have an appetite for the normal in my life, as well as the abnormal. Benedict Cumberbatch
normal possible
We want it to be as normal as possible for the kids. Max Miller
normal possible setting
We want it be as normal a setting as possible and not have them stigmatized as being retarded. Jim Hall
nuclear weapons acquisition
The Iranian acquisition of nuclear weapons would be infinitely more costly than any scenario you can imagine to stop it. Benjamin Netanyahu
nuclear problem
We have never had a problem with the nuclear reactor and it has been here for 38 years. Todd Simmons
nuclear weapons mass
If there was a market in mass-produced portable nuclear weapons, we'd market them, too. Alan Sugar
nuclear technology valuable
U.S. nuclear technology is one of this nation's most valuable secrets, and it should have been protected. Charles Bass
nuclear-terrorism forever suffering
Nuclear terrorism is one of the most serious threats of our time. Even one such attack could inflict mass casualties and create immense suffering and unwanted change in the world forever. This prospect should compel all of us to act to prevent such a catastrophe. Ban Ki-moon
nuclear-disarmament world path
Nuclear disarmament is the only sane path to a safer world. Ban Ki-moon
nuclear looks comedy
The great thing about Glasgow is that if there's a nuclear attack it'll look exactly the same afterwards. Billy Connolly
nuclear foundation trouble
While politicians, clergy, creators of advertisements, and other worthies assert stoutly that the family is the foundation of society, the nuclear family, as an institution, is currently in grave trouble. Jane Jacobs
nuclear bombs physicist
The one great gift to humankind from our nuclear physicists has been the nuclear bomb. How can we ever thank them? Edward Abbey
starting
I like starting. It's pretty cool. Al Leiter
starting-out starting hard
It must be really hard to be starting out in music now. Bryan Ferry
starting-over kindergarten wells
We'd all do well to start over again, preferably with kindergarten. Kurt Vonnegut
starting-over teapots starting
Originally I planned on starting a teapot collection. I really like them. Billy Dee Williams
starting-over finding-yourself world
I ain't never found no place for me to fit. Seem like all I do is start over. It ain't nothing to find no starting place in the world. You just start from where you find yourself. August Wilson
starting-over
I really can't watch myself. I just get too in my head about it and start overthinking everything. Eden Sher
starting difficult circumstances
It never really was difficult for me not starting because I understood the circumstances. Cedric Benson
starting-out firsts starting
When I was first starting out, and I was less established, I was really concerned about being typecast. Charisma Carpenter
starting
We're starting to get a little more notice. Rob Jordan
transplants liver
I had to have a complete liver transplant. Shelley Fabares
work quality may
Although profoundly "inconsequential," the Zen experience has consequences in the sense that it may be applied in any direction, to any conceivable human activity, and that wherever it is so applied it lends an unmistakable quality to the work. Alan Watts
work apology giving
Give a civil servant a good case and he'll wreck it with clichés, bad punctuation, double negatives, and convoluted apology. Alan Clark
work mean doing-nothing
If I am doing nothing, I like to be doing nothing to some purpose. That is what leisure means. Alan Bennett
work sleep thinking
A gentleman ... sleeps at his work. That's what work's for. Why do you think they have the SILENCE notices in the library? So as not to disturb me in my little nook behind the biography shelves. Alan Ayckbourn
work play able
You've got to get good habits of working hard so that when that play comes up during the regular season that you're able to complete it and do it the right way. Al Kaline
work people kind
Japanese people tend to be much better adjusted to the notion of work, any kind of work, as honorable. Akio Morita
workout training cardio
I do a dance-based cardio workout infused with circuit training, and emphasizing strength and alignment. Chloe Sevigny
work-out effort feels
If I put forth a legitimate effort, then I feel like, if that doesn't work out, that's all I can do. Dave Chappelle
work-out levels mail
I always take a relationship to the next level. If that works out, I take it to the next level after that, until I finally reach that level when it becomes absolutely necessary for me to leave. Dave Chappelle
years needs answers
Any replacement to the current copyright position (life plus 70 years) needs to have an answer lined up for this, and similar, messy edge cases. Charles Stross
years preparation left
If I knew I had 25 years left to live, I would spend 20 of them in preparation. Charles Spurgeon
years oil alchemist
I'm a bit of an alchemist sorceress. I've collected probably 1500 oils from around the planet over the last ten years. I'm kind of obsessed with the sensuality of it. Alanis Morissette
years white black
...for thousands of years human history has been a magnificently futile conflict, a wonderfully staged panorama of triumphs and tragedies based on the resolute taboo against admitting that black goes with white. Alan Watts
years people car
Although the quality of the vehicles is tremendously improving year after year but the underlying reasons that people are buying cars have really gotten focused. It's for high quality vehicles, reliable, fuel-efficient, and safe of course. Alan Mulally
years mad people
I've known a lot of people go mad over the years, and it is more distressing than people dying. People dying is quite natural, people going mad is the complete antithesis of that. Alan Moore
years rose three
It seems strange that my life should end in such a terrible place, but for three years I had roses, and apologized to no one. Alan Moore
years style looks
It's funny, but certain faces seem to go in and out of style. You look at old photographs and everybody has a certain look to them, almost as if they're related. Look at pictures from ten years later and you can see that there's a new kind of face starting to predominate, and that the old faces are fading away and vanishing, never to be seen again. Alan Moore
years childhood arlington
I was born in Somerville, but I don't remember very much about it because we moved from there to Arlington when I was five years old, and it was in Arlington that I spent most of my childhood. Alan Hovhaness
yield air oxygen
A mouthful of sea air, or a stiff walk in the wind's face would not give grace to the soul, but it would yield oxygen to the body, which is next best Charles Spurgeon
yield giving
When we yield ourselves completely to God, He gives Himself completely to us. Aiden Wilson Tozer
yield
God must do everything for us. Our part is to yield and trust Aiden Wilson Tozer
yield world complexes
Everybody has a world, and that world is completely hidden until we begin to inquire. As soon as we do, that entire world opens to us and yields itself. And you see how full and complex it is. David Guterson
yield optimism rewards
Firm and patient optimism always yields its rewards. Carlos Slim
yield tears treasure
The Bible was written in tears, and to tears it yields its best treasures. Aiden Wilson Tozer
yield acting finishing
It is impossible for any rational creature to be happy without acting all for God. God Himself could not make him happy any other way... There is nothing in the world worth living for but doing good and finishing God's work, doing the work that Christ did. I see nothing else in the world that can yield any satisfaction besides living to God, pleasing Him, and doing his whole will. David Brainerd
yield long doe
This bill is the legislative equivalent of crack. It yields a short-term high but does long-term damage to the system and it's expensive to boot. Barney Frank
yield political-will challenges
Immigration reforms are always controversial. Our Congress was created to muster political will to answer such challenges. Today we didn't, but tomorrow we will. I yield the floor. Edward Kennedy