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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
forces plans present rule time
We're not going to rule out anything, but we don't have any plans at the present time to use U.S. forces in that way, Donald Rumsfeld
forces listened music radio
When I was a kid,if you were lucky, you listened to that music on Radio Luxembourg or the American Forces Network. Georgie Fame
forces particles
Investigating the forces that hold the nuclear particles together was a long task. Richard P. Feynman
forces prey
I know how tough it is to stand up to powerful forces that prey on consumers. Kathleen Sebelius
forces four game position
When you put yourself in the position to have to come back like that it forces your hand. You have to make every play and you can't make a mistake. But the story of this game was told in the first four minutes. Eric Long
forces huge move present pressure puts tough
She puts huge pressure on me. She is so present on the court. She really forces you back. It's tough to get the rallies going and move her around. Patty Schnyder
forces helped medical provide scene support urgent
What I can say is that U.S. forces helped to provide urgent medical support at the scene of the incident, something for which I know our forces are grateful, R. Ingram
forces respond security strength terrible
Security forces must respond with strength to the terrible attack. Yosef Lapid
forces harness might various
If you are a Representative and want to be a Senator, you must be careful not to do anything which might upset the various forces you need to harness to get elected. Gore Vidal
given no-hope pledge
God has given no pledge which He will not redeem, and encouraged no hope which He will not fulfill. Charles Spurgeon
given guy guys perception
The perception now is that (Woods) is still the guy to beat. But I don't think guys think it's a given that he's going to win. Lee Janzen
given park rules
We've already given them an extension. It's really simple: The rules of the park have to be followed. Sharon Stewart
given life lived name people talk tony
I hate it when people talk about Tony Curtis and say: 'His real name was Bernie Schwartz... ' That was just the name that he was given at birth. It's not the person he lived his life with, and became. Nicolas Roeg
given movies sad
A lot of my movies have come to be thought about only years after the fact, and I'm sad about that but also happy about it in a way, as it's given them longevity. Nicolas Roeg
given relevant considering
I have given up considering happiness as relevant. Edward Gorey
given hoard wealth
Wealth that you hoard is not yours; wealth that you have given is really yours. Sathya Baba
given heck love sharks shocked
What the Sharks did, it shocked the heck out of me. We've always been rivals, but I think they know how much I love this game, and how much I've given to it. Luc Robitaille
given
We have assumed control where once we worked with what we were given. Bill McKibben
greater inflame piece potential value
the potential to inflame is greater than the value of the piece itself. Bob Zelnick
greater market moderation pace rates seeing slightly
We are seeing a market that has experienced extraordinary rates of growth. We are seeing those rates moderate. That pace of moderation has been slightly greater than we expected. Richard Segal
greater successes suffers
Even the accomplished suffers setbacks sometimes. The more bitter the lessons, the greater the successes will be. Lucio Tan
greater
Whenever God restores something, He restores it to a place greater than it was before. Bill Johnson
greater interest name sum
We have no interest in a name on a masthead. With any partnership, you want the whole to be greater than the sum of the parts. Doug MacGregor
greater insight looking power questions stories ways
I'm really looking at questions of power, navigation, and spin. Then I am also looking for real-world stories that give me greater insight into smart and new ways of thinking. Noreena Hertz
greater
We feel that we are greater than we know. William Wordsworth
greater love requires theatre ways
Yes, in a way. Film is a by-product of my love of theatre. Theatre is for me the greater challenge. In many ways it requires more skill. Joseph Fiennes
greater hoping oftentimes process public understanding
The process is oftentimes too mysterious, and the public has a right to know. We're hoping that there will be a greater understanding of the process. Rick Costa
lasts remember there-is-hope
Remember, to the last, that while there is life there is hope. Charles Dickens
lasts fool firsts
Ridicule is the first and last argument of a fool. Charles Simmons
lasts dubbing spokes
I have just returned from the dubbing studio where I spoke into a microphone as Severus Snape for absolutely the last time. Alan Rickman
last nine won
We've won nine of the last 11, so I like our chances. Eric DiBiase
last people ready year
We want to show that we're no joke. People thought last year was a fluke. We can make improvements from last year. We're ready to see what's out there. Andrew Palmer
lasts eloquent last-time
We looked at each other for the last time; nothing is as eloquent as nothing. David Mitchell
lasts records haircuts
You're only as good as your last record. David Sanborn
lasts female worship
The last western society to worship female powers was Minoan Crete. And significantly, that fell and did not rise again. Camille Paglia
lasts needs kind
I need some kind of... like... last minute, poorly-set-up deus ex machina!! Bryan Lee O'Malley
mankind historian dependence
What would become of history, had we not a dependence on the veracity of the historian, according to the experience, what we have had of mankind? David Hume
mankind humankind knows
What science cannot tell us, mankind cannot know. Bertrand Russell
mankind
Mankind naturally and generally love to be flatter'd. Benjamin Franklin
mankind opposition
Mankind are dastardly when they meet with opposition. Benjamin Franklin
mankind
Science is the only religion of mankind. Arthur C. Clarke
mankind shall
When there's only one race, and that's mankind, we shall be free. Garth Brooks
mankind draws
You draw closer to truth by shutting yourself off from mankind. Elias Canetti
mankind consolation solemn
The act of naming is the great and solemn consolation of mankind Elias Canetti
mankind interest consulting
Statesman are suspected of plotting against mankind, rather than consulting their interests, and are esteemed more crafty than learned. Baruch Spinoza
nature giving natural
Nature gives to every time and season some beauties of its own. Charles Dickens
nature humility pride
We cannot think too highly of our nature, nor too humbly of ourselves. Charles Caleb Colton
nature men self
If Natur has gifted a man with powers of argeyment, a man has a right to make the best of 'em, and has not a right to stand on false delicacy, and deny that he is so gifted; for that is a turning of his back on Natur, a flouting of her, a slighting of her precious caskets, and a proving of one's self to be a swine that isn't worth her scattering pearls before. Charles Dickens
nature moon shining
When the moon shines very brilliantly, a solitude and stillness seem to proceed from her that influence even crowded places full of life. Charles Dickens
nature dark moon
The earth covered with a sable pall as for the burial of yesterday; the clumps of dark trees, its giant plumes of funeral feathers, waving sadly to and fro: all hushed, all noiseless, and in deep repose, save the swift clouds that skim across the moon, and the cautious wind, as, creeping after them upon the ground, it stops to listen, and goes rustling on, and stops again, and follows, like a savage on the trail. Charles Dickens
nature wall dark
A moment, and its glory was no more. The sun went down beneath the long dark lines of hill and cloud which piled up in the west an airy city, wall heaped on wall, and battlement on battlement; the light was all withdrawn; the shining church turned cold and dark; the stream forgot to smile; the birds were silent; and the gloom of winter dwelt on everything. Charles Dickens
nature morning fall
It was a cold hard easterly morning when he latched the garden gate and turned away. The light snowfall which had feathered his schoolroom windows on the Thursday, still lingered in the air, and was falling white, while the wind blew black. Charles Dickens
nature dark winter
The white face of the winter day came sluggishly on, veiled in a frosty mist; and the shadowy ships in the river slowly changed to black substances; and the sun, blood-red on the eastern marshes behind dark masts and yards, seemed filled with the ruins of a forest it had set on fire. Charles Dickens
nature wall rain
Not only is the day waning, but the year. The low sun is fiery and yet cold behind the monastery ruin, and the Virginia creeper on the Cathedral wall has showered half its deep-red leaves down on the pavement. There has been rain this afternoon, and a wintry shudder goes among the little pools on the cracked, uneven flag-stones, and through the giant elm-trees as they shed a gust of tears. Charles Dickens
powers respect several
Mr. Harper said several times that he did not want to centralize, that he wanted to respect the powers of the provinces. Michel Gauthier
powers remain western
Western powers remain imprisoned by the idea that the world is a dangerous place, that it needs to be managed, and that they are called upon to do the managing. Stephen Kinzer
powers together work
I think it can. The powers that be, IMG, the ATP, need to work together more coherently. John McEnroe
powers respect several
Harper said several times that he did not want to centralize, that he wanted to respect the powers of the provinces. Michel Gauthier
powers recognize
We all are going to outplay and outperform what we do and it's up to the powers that be to recognize that and acknowledge that. Brian Kelly
powers work
powers at work about which we have no knowledge. Walter Rodgers
powers
If you devolve all the powers to the provinces, what do you have left? Buzz Hargrove
powers received selected
All I know is the powers that be selected us to be in this game. We just received the trophy. Matt Mauck
previous whether
I don't know whether it ever comes back to the same thing; it does return to the spirit of a previous period in some way, but it's different, it's new. Norman McLaren
previous
As a game creator, I'm not 100% satisfied when looking back at the previous game that I released. Hideo Kojima
previous producer
Of course, completely, ... My previous producer always said we were there to learn. Chris Tarrant
previous wondered
Watching previous figure skaters, I always wondered why they cried after their performance. Kim Yuna
previous quite sort spent surprising ten
Yes, there was a sort of underground cult following, which came from nowhere, and grew, and grew. It was quite surprising to us all, because all of us had spent probably the previous five to ten years without it. So it was quite overwhelming. Overwhelming and humbling. Michael Giles
previous
We'll have to go back and resample all the previous sampled locations. George Foster
previous took
Previous governments, particularly the one before I took over, mismanaged the economy quite badly. George Papandreou
previous received
This is what happened to me when I received the governorship. The corrupt previous governor didn't do the handover. We received the Miranda governorship completely dismantled. Henrique Capriles Radonski
previous shown studies surprising
That was surprising to us. The previous studies had not shown as much. William Mosher
science uniforms taste
In science, reason is the guide; in poetry, taste. The object of the one is truth, which is uniform and indivisible; the object of the other is beauty, which is multiform and varied. Charles Caleb Colton
science disorder cures
No disorders have employed so many quacks, as those that have no cure; and no sciences have exercised so many quills, as those that have no certainty. Charles Caleb Colton
science mind cost
The acquirements of science may be termed the armour of the mind; but that armour would be worse than useless, that cost us all we had, and left us nothing to defend. Charles Caleb Colton
science tolerance religion
We are not clear as to the role in life of these chemicals; nor are we clear as to the role of the physician. You know, of course, that in ancient times there was no clear distinction between priest and physician. Alan Watts
science judging hammers
What happens if a big asteroid hits Earth ? Judging from realistic simulations involving a sledge hammer and a common laboratory frog, we can assume it will be pretty bad. Dave Barry
science animal mph
Scientists tell us that the fastest animal in the world, with a speed of 120 mph, is a cow dropped out of a helicopter. Dave Barry
science simple water
Here's a simple experiment that you might want to try if there is absolutely nothing else going on in your life. All you need is a cork, a bar magnet, and a pail of water. Simply attach your magnet to your cork, then drop it into the water, and voilà (literally, "you have a compass")-you have a compass. How does it work? Simple. Notice that, no matter which way you turn the bucket, the cork always floats on top of the water (unless the magnet is too heavy). Using this scientific principle, early hardy mariners were able to tell at a glance whether they were sinking! Dave Barry
science years careers
I ... began my career as a wireless amateur. After 43 years in radio, I do not mind confessing that I am still an amateur. Despite many great achievements in the science of radio and electronics, what we know today is far less than what we have still to learn. David Sarnoff
science oxygen breathe
Freedom is the oxygen without which science cannot breathe. David Sarnoff