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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
country easy walks
It is not easy to walk alone in the country without musing upon something. Charles Dickens
country men climate
In all countries where nature does the most, man does the least. Charles Caleb Colton
country travel home
Those who visit foreign nations, but associate only with their own country-men, change their climate, but not their customs. They see new meridians, but the same men; and with heads as empty as their pockets, return home with traveled bodies, but untravelled minds. Charles Caleb Colton
country sadness men
In great cities men are more callous both to the happiness and the misery of others, than in the country; for they are constantly in the habit of seeing both extremes. Charles Caleb Colton
country heart simple
As the grand discordant harmony of the celestial bodies may be explained by the simple principles of gravity and impulse, so also in that more wonderful and complicated microcosm, the heart of man, all the phenomena of morals are perhaps resolvable into one single principle, the pursuit of apparent good; for although customs universally vary, yet man in all climates and countries is essentially the same. Charles Caleb Colton
country self names
The most notorious swindler has not assumed so many names as self-love, nor is so much ashamed of his own. She calls herself patriotism, when at the same time she is rejoicing at just as much calamity to her native country as will introduce herself into power, and expel her rivals. Charles Caleb Colton
country mean hands
Old Marley was as dead as a doornail. Mind! I don't mean to say that, of my own knowledge, what there is particularly dead about a doornail. I might have been inclined, myself, to regard a coffin-nail as the deadest piece of ironmongery in the trade. But the wisdom of our ancestors is in the simile; and my unhallowed hands shall not disturb it, or the Country's done for. You will therefore permit me to repeat, emphatically, that Marley was as dead as a doornail. Charles Dickens
country night men
If its individual citizens, to a man, are to be believed, it always is depressed, and always is stagnated, and always is at an alarming crisis, and never was otherwise; though as a body, they are ready to make oath upon the Evangelists, at any hour of the day or night, that it is the most thriving and prosperous of all countries on the habitable globe. Charles Dickens
country character men
Rattle me out of bed early, set me going, give me as short a time as you like to bolt my meals in, and keep me at it. Keep me always at it, and I'll keep you always at it, you keep somebody else always at it. There you are with the Whole Duty of Man in a commercial country. Charles Dickens
either good help hurt individual seeds
There are some good individuals there. You can either help yourself or hurt yourself for seeds (in the Individual District) Saturday. Tim Roberts
either garbage outside people sit
We're in a quandary on what we can and can't do. Either you let the garbage sit outside or people are going to put it in their neighbor's yard. Chuck McMeekin
either election face four minister occur prime seem wait
What the prime minister doesn't seem to face is the election is either going to occur now or it's going to occur in January, ... We're not going to wait another four months. Stephen Harper
either half minutes played second time together whenever
Whenever we played them, we played well in either the first half or the second half. This time we've got to put it together for 40 minutes if we want to win. Ivan Radenovic
either extract extremists points
When extremists extract concessions from democracies on points of principle, either by blackmail or terror, democracies do not have long left. Philippe Val
either gets good kicking open opportunity plays scoring
When he gets the opportunity to be in the open court, he's so good with the ball. He makes good plays by either scoring or kicking it out to other people. Tim Parmeter
either forces worse
We were behind, and that forces things to happen. It either makes things better or makes it a little worse, and it made it a little worse tonight. Ed Beattie
either fall gone late man nice team zone
We were an all-zone team early, but we've gone back to a man-to-man late in the season. I feel we can play either one. In the post-season it's nice to be able to fall back on a zone if the man isn't working. Brian Norberg
either forward improve step trying
We were trying to improve fundamentally. You either take a step forward or a step back every day. You've got 15 opportunities, and we need to get better all 15 times out. Will Muschamp
foundation emotion reason
Emotion is the foundation of reason. David Brooks
foundation donation
I am the donation to the foundation. Baron Davis
foundation should lost
If all the music written since Bach's time should be lost, it could be reconstructed on the foundation which Bach laid. Charles Gounod
foundation secrecy
Secrecy is the foundation of politics. Bing Gordon
foundation hold laws society somebody trust trusted war whether
Whether we're at war or have been attacked, the foundation of society is that you hold to the laws in place. I used to be somebody that trusted the government. Now I really don't trust anything. Steven Hatfill
foundation statistics theory
Even theories must have foundations. Edgar Rice Burroughs
foundation
When Tarzan killed he more often smiled than scowled, and smiles are the foundation of beauty. Edgar Rice Burroughs
foundation laid pitches society
My foundation now has some 120 football pitches laid out for children, a lot of them immigrants. We live in a multicultural society. Johan Cruyff
foundation gives high improved team
We have improved the foundation of this team with young players. It gives you high hopes. Bruce Allen
history who-we-are way
History is a guide to navigation in perilous times. History is who we are and why we are the way we are. David McCullough
history want done
No harm's done to history by making it something someone would want to read. David McCullough
history social shank
History is the shank of the social sciences. C. Wright Mills
history lafayette might
For women, history does not exist. Murasaki, Sappho, and Madame Lafayette might be their own contemporaries. Cesare Pavese
history want grants
Everyone wants to be Cary Grant. Even I want to be Cary Grant. Cary Grant
history
When you think about it, history is made to be broken. That's the way we look at it. E. Hicks
history lists surprise
History is merely a list of surprises. It can only prepare us to be surprised yet again. Kurt Vonnegut
history
History! Read it and weep! Kurt Vonnegut
history disposition efficacy
But the power of instruction is seldom of much efficacy, except in those happy dispositions where it is almost superfluous. Edward Gibbon
layers foundation complexion
I layer my moisturizers, which makes my complexion so fresh, I can wear less foundation. Bobbi Brown
laying-down bones punk
We are simultaneously the most hated, loved, feared and admired nation on this planet. In short, we are Frank Sinatra. And the Chairman didn't make his bones laying down for punks... Dennis Miller
layers onions cry
It was what we Japanese called the onion life, peeling away a layer at a time and crying all the while. Arthur Golden
lay life love
Greater love has no one than this, than to lay down one's life for his friends. John the Apostle
lay
I go on benders where I just exercise like a maniac. And then I go on benders where I just can only take baths. Like, I have to lay down to bathe, and I could go on that for six months. Sharon Stone
layers higher
There's a magical layer of love that's laced, designed to take us to a higher place. Bootsy Collins
laying-down scripture love-one-another
To lay down one's life for the truth. Juvenal
laying life
For many, living a Christlike life every day may be even more difficult than laying down one's life. James E. Faust
lay pool
I didn't have a pool growing up, and we went to the beach to lay out and get sun. Erika Eleniak
practicing six stand trees
I started doing '30 Rock' and started writing 'Mystery Team' at the beginning of that. While I was doing 'Mystery Team,' I started practicing stand-up. While I was doing stand up, I got 'Community.' It's like I planted trees six years ago, and now they have fruit. Donald Glover
practicing tend time
I don't have a very disciplined approach to practicing or anything, but I do tend to have a guitar around most of the time, which I strum on most of the day. David Gilmour
practicing
Just like any other game we're taking on we've got to prepare, prepare hard, mentally, physically. We've been practicing hard. Rob Gronkowski
practicing status sure
He's been practicing and he's in school, but I'm not sure what his status is going to be. Royce Waltman
practicing
If it wasn't a bye week, he probably would be practicing and going through the things he had been going through. Chuck Barta
practicing trouble
If we aren't practicing now we're going to be in trouble in April. Dan Brown
practicing studied
I went to the Technion and studied with Avram Hershko. I found it more exciting than practicing medicine. Aaron Ciechanover
practicing
We've been practicing hard. Right now, we're clicking. Ryan Griffin
practicing ready tired
We're tired of practicing and we're tired of scrimmaging. We're ready to play. Scott Baugh
struggling
It's no fun to be a struggling young actor. It's a desperate thing, no way to be happy. If you have any alternative, you should take it. Tommy Lee Jones
struggling
Inside of many liberals is a fascist struggling to get out. John McCarthy
struggling
I didn't have all my control. I was struggling down in the zone. Scott Kazmir
struggling team
Well, the team he went to is struggling mightily, I would say. Scott Skiles
struggling
We've got to get better at serving, because we are really struggling with that right now. Jeri Morin
struggling
We're struggling with what we do with these things. Patrick Halsted
struggling
We're struggling to survive, ... We can't go down after 59 years. Sharon Alexander
struggling
We're struggling to get there. But we're still hopeful. Jeff Kasko
struggling
We're struggling to get back to where we were years ago. It's a cycle. Bryant Young