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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
bit positive turn
We want to take a little bit of this frustration and turn it into some positive momentum. Michael Goodling
bit grass hanging love prefer republican street
My style is a little bit different than most conventional Republican Party chairmen. My style is more grass roots-oriented. I'm much more of a street guy. I love hanging out in boardrooms, but I prefer to be in neighborhoods and communities. Michael Steele
bit difference higher maybe providence somebody talented teams
The only difference between Providence and maybe somebody a little bit higher in the standings is the young kids. Providence is talented but they're young. Young teams make mistakes. Jim Calhoun
bit final finish luck potential programs spots strong three top
The potential is there and with a bit of luck we could finish in the top four. There are two or three programs that are traditionally strong and the final one or two spots are usually up for grabs. Paul Woods
bit economic economy economy-and-economics energy gracefully higher move potential prices risk
The potential for even higher energy prices is a risk to the economic outlook. The economy has digested the higher prices gracefully so far. But it can get a bit of indigestion if prices move higher. Mark Zandi
bit national people talent talented team tonight won
The people who were here tonight now have an idea of the talent you see at the NAIA National Tournament. This team is every bit as talented as what you see at the nationals. In fact, if this had been 20 years ago when the NAIA had 600 teams, this team could have won it. Pat Sullivan
bit building built deciding model people precedent spaceship structures
The people who built the first of these structures had no model to go by, no precedent to use in building a monument. It's a bit like deciding to build a functioning spaceship in your back yard, and succeeding. Winifred Creamer
bit chris forced open throw wide
We've always been a little bit wide open anyway, but with Chris out, it kind of forced us to throw more. Mike Hathaway
bits bob brian coming dylan hopefully lots sit song stuff together totally type
We've all got lots of different influences. We never sit down to write a song and say, 'This is going to be a Brian Eno type of song,' or 'This is a Bob Dylan song.' It's totally little bits of lots of different stuff that come together and hopefully it's something coming out of us that we're creating. Robbie Guertin
conditions environment family
We are fashioned not by our genes, but by our environment - by the family and socio-historic conditions in which we evolve. Michel Onfray
conditions monetary strength
The pound's strength is tightening monetary conditions in the U.K., but it's not enough. Stewart Newnham
conditions consumer continue high improvement labor spending support wage
The possibility is high that an improvement in labor and wage conditions will continue to support consumer spending going forward. Taro Saito
condition cultural personal spread travel-and-tourism
The personal appropriation of clichTs is a condition for the spread of cultural tourism. Serge Daney
conditions saw seeing similar
We are seeing conditions that are similar to about what we saw in 2002. William Paul
conditions diseases infectious preparing spread
We are preparing for the possibility of infectious diseases that could be spread under conditions of crowding in shelters, Julie Gerberding
conditions looking martha violated whether
We are looking into whether Martha Stewart violated the conditions of her release, Chris Stanton
conditions country create divided government
There are conditions to create a government and to govern, even if the country is divided in two. Piero Fassino
conditions four handle three
There are some conditions we just can't handle here. Like dialysis. We can't do that, and they'll be here three or four days, so they'll need it before then. Kevin Stephens
infection
I finally demonstrated that typhus infection is not hereditary in the louse. Charles Jules Henry Nicole
infection time
I had a MRSA infection on my ankle. At the time, I had never heard of MRSA. I didn't really know a whole lot about it. It really scared me. Grant Hill
infection
He had an infection to the bronchial line, which he never had. David Flanagan
infection overcome realized strength
We realized it was an infection issue. They didn't have the strength to overcome any resistance. Jennifer Miller
infection needs people till totally treated
A lot of people were totally in chaos. I have an infection that needs to be treated and I couldn't do anything till this morning. H. Hart
infection terms time
This is the first time that we have third-generation infection in terms of laboratory-acquired infection. Shigeru Omi
infection rampant
Infection had set in, and it was rampant in the frontal bone, Lee Wood
infection worst
It's still climbing. It's not the worst we've seen, but the infection is sizable. Mikko Hypponen
infection likelihood preventing spread
In practice, the likelihood of preventing spread of infection in those circumstances is very limited. John Watson
lasts remember there-is-hope
Remember, to the last, that while there is life there is hope. Charles Dickens
lasts fool firsts
Ridicule is the first and last argument of a fool. Charles Simmons
lasts dubbing spokes
I have just returned from the dubbing studio where I spoke into a microphone as Severus Snape for absolutely the last time. Alan Rickman
last nine won
We've won nine of the last 11, so I like our chances. Eric DiBiase
last people ready year
We want to show that we're no joke. People thought last year was a fluke. We can make improvements from last year. We're ready to see what's out there. Andrew Palmer
lasts eloquent last-time
We looked at each other for the last time; nothing is as eloquent as nothing. David Mitchell
lasts records haircuts
You're only as good as your last record. David Sanborn
lasts female worship
The last western society to worship female powers was Minoan Crete. And significantly, that fell and did not rise again. Camille Paglia
lasts needs kind
I need some kind of... like... last minute, poorly-set-up deus ex machina!! Bryan Lee O'Malley
lungs struggling
One of his lungs had collapsed. He couldn't breathe. You could see him struggling for air. Glen Davis
lungs
my lungs sucked at being lungs. John Green
worse
I was nervous from the very beginning, and it got worse as the years went on. I was conscientious and wanted to do more, always, than I was able. I don't think, when I was playing, that I was ever happy - beginning at 4 o'clock any afternoon. Katharine Cornell
worse
Just when I thought we couldn't get any worse or go any lower, we find another way to do it. Quentin Richardson
worse
I don't think I can do this - painting under observation. It's the worst thing there is, worse than being in the hospital. Gerhard Richter
worse
He's day to day. He's no better or worse than he was yesterday. Dusty Baker
worse
It could be a whole lot worse then where we are. Derrick Brooks
worse
I thought 'Game of Thrones' had this challenge in filming, and it's one of those things you think, 'It can't get worse than this,' because it's really cold, and you're in pain, and it's miserable. Richard Madden
worse
I would have expected, even without FD, to see more preannouncements this quarter. Things are worse out there. Chuck Hill
worse
If we do nothing, things will get that much worse sooner. Sean McCarthy
worse
I got out there and it was just stiff. It got progressively worse the more I moved. I just didn't feel real comfortable for the whole match. Andy Roddick