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We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
isolated near
But it was beautiful, isolated and near enough to anything you could want. Debbie Anthony
isolated larger piece wore
I think it is an isolated situation. It's just a piece that wore out. I don't think it's symptomatic of a larger problem. Jeff Fontaine
isolated
I would characterize it as an isolated problem. Donald Rumsfeld
isolated nutrients obtained people studied useful
Marge, old people don't need companionship, they need to be isolated and studied to see what useful nutrients can be obtained from them... Dan Castellaneta
isolated
We wanted to kill the clock. We wanted to get Lance isolated so he could make the shot. Greg Sparling
isolated people
People said, 'Maybe this is an isolated event,' E. Hurley
isolated
After 16 years, we're there. We've isolated it, and we can synthesize it. Peter Sorensen
isolated terribly twenty
During all my first twenty years, I was depressed, terribly unhappy, lonely, isolated (and self-rejecting). Abraham Maslow
isolated seems
It seems to not be an isolated incident. Richard Kelly
largest missing properties sample
We know we have the largest properties in the sample and what we are missing is going to be very small. Kathy Deck
largest plants
The plants that are going to be the largest 10 years from now should be the largest ones you put in the ground. Lee Quillen
largest million night sheltered
We sheltered about 3.5 million people. The largest night was about 150,000. Joe Becker
largest poles
There are enough Poles in Chicago to make up one of the largest cities in Poland. Suzanne Fields
largest progress wish
To wish to progress is the largest part of progress. Lucius Annaeus Seneca
largest
We are a breathtakingly alienated people... One of my props is the world's largest underpants. I've had the president of Costa Rica in my underpants with me. Patch Adams
largest million spoke
I spoke to a million in one service, in Korea, in Seoul. And that was the largest audience I ever have had. Billy Graham
largest
More than half the world's largest 100 economies are corporations. They have no loyalties to place or citizens. Zac Goldsmith
largest moved people power response
People were so moved by the power of what Sara and Yvonne have done, and it's the largest response I've had for any movie that I've done. Craig Anderson
nuclear weapons acquisition
The Iranian acquisition of nuclear weapons would be infinitely more costly than any scenario you can imagine to stop it. Benjamin Netanyahu
nuclear problem
We have never had a problem with the nuclear reactor and it has been here for 38 years. Todd Simmons
nuclear weapons mass
If there was a market in mass-produced portable nuclear weapons, we'd market them, too. Alan Sugar
nuclear technology valuable
U.S. nuclear technology is one of this nation's most valuable secrets, and it should have been protected. Charles Bass
nuclear-terrorism forever suffering
Nuclear terrorism is one of the most serious threats of our time. Even one such attack could inflict mass casualties and create immense suffering and unwanted change in the world forever. This prospect should compel all of us to act to prevent such a catastrophe. Ban Ki-moon
nuclear-disarmament world path
Nuclear disarmament is the only sane path to a safer world. Ban Ki-moon
nuclear looks comedy
The great thing about Glasgow is that if there's a nuclear attack it'll look exactly the same afterwards. Billy Connolly
nuclear foundation trouble
While politicians, clergy, creators of advertisements, and other worthies assert stoutly that the family is the foundation of society, the nuclear family, as an institution, is currently in grave trouble. Jane Jacobs
nuclear bombs physicist
The one great gift to humankind from our nuclear physicists has been the nuclear bomb. How can we ever thank them? Edward Abbey
states secretary
I loved what I did. I could've been secretary of state for ever. Madeleine Albright
states evident secretary
I loved being Secretary of State, that's probably evident to everyone who watched me. Madeleine Albright
states barometer interest
...interest is the barometer of the state... David Hume
states hyperbole constant
I live in a constant state of hyperbole. Eden Sher
states senators productive
I was very productive as a senator for my state. Carol Moseley Braun
states united
I have not broken the laws of the United States or the laws of the Dominican Republic. Sammy Sosa
states loses
Better lose me than lose a state. Susan B. Anthony
states subjects susceptibility
writers do not find subjects: subjects find them. There is not so much a search as a state of open susceptibility. Elizabeth Bowen
states united wants
Nobody wants to put the creditworthiness of the United States in jeopardy. Nobody wants to see the United States default. So we've got to seize this moment, and we have to seize it soon. Barack Obama