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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
assistance call contact payment
We want them to call us, so payment arrangements can be made, so they can be put in contact with any assistance that's available. Allan Urlis
assist equipment private pull resources sector secure stay technology
We want to stay cutting-edge, we want to pull in the private sector who has the technology and the resources to assist us with ... state-of-the-art equipment we will need to secure the border. Jarrod Agen
assistance decision economic front increases korea north somewhat
The possibility of North Korea making a (positive) decision increases somewhat if economic assistance is dangled in front of their eyes. Noriyuki Suzuki
assist breaks budgets bush child children congress conscious continue cut economic enormous food growing high left level misguided persistent poor poverty programs recovery reflects stamps tax
The persistent and growing high level of child poverty reflects conscious and misguided choices, ... How can the Bush Administration and Congress give enormous tax breaks to the wealthiest Americans who have benefited most from the economic recovery while threatening to cut the budgets for Medicaid, Food Stamps and other programs that assist poor children who continue to be left behind? Marian Edelman
assistance basically clothes glad homes people sure whatever
The people who have been in this devastation don't have anything. They don't have their homes anymore. They don't have any of their belongings. They basically got away with the clothes on their back and little else so I'm sure whatever assistance they can get they're very glad for. Grant Woods
assistance draw emergency execute federal fema grant local managing office people plans response reviewing state taking
The people who draw up the plans should be able to execute the plans. Now we have one office taking in grant applications, reviewing emergency plans by state and local governments and determining where federal assistance should go, yet FEMA is tasked with managing the response and marshalling the assets. Paul Anderson
assistance draw emergency execute federal fema grant local managing office people plans response reviewing state taking
The people who draw up the plans should be able to execute the plans, ... Now we have one office taking in grant applications, reviewing emergency plans by state and local governments and determining where federal assistance should go, yet FEMA is tasked with managing the response and marshaling the assets. Paul Anderson
assistance economic fair help personnel prepared provide
We are prepared to provide help in any way we can to those Fair Grounds personnel who need economic assistance and housing. Bryan Brown
assistance balance countries existing experience financial programs provide providing support
We are prepared, as in the past, to provide financial support by augmenting existing programs or by providing new financial assistance to countries that experience drought-related balance of payments needs. Rodrigo Rato
blocks defense outside passing played serving tougher
We started passing well. We played defense a little better, we started getting blocks outside and we were serving a little tougher ourselves. Travis Wright
blocks four games missed played serves sloppy three
We still missed too many serves and we played a little sloppy in games one and two. We played better in games three and four and there were streaks where our blocks were real good." () Terri McColloch
blocks efficient pass running sustaining tackling
We have to get better technically in all phases. Sustaining our blocks (running game), pass blocking, being more efficient passing, getting a better pass rush, tackling ... Andy Bitto
blocks constantly dominate falls lords opposite push rather sings swift taylor teaches time tweak
Most of the time in the 21st century, we dominate our surroundings: We tweak the thermostat, and the temperature falls one degree. We push a button, and Taylor Swift sings for us. It's the opposite in the wilderness, which teaches us constantly that we are not lords of the universe but rather building blocks of it. Nicholas Kristof
blocks call football plays practiced separation testament toughness treatment whether
Whether you call it a low-grade separation or a contusion, he practiced every day. He won't get treatment for it. He blocks out pain. He plays through it. It's a testament to his toughness as a football player. Gregg Williams
blocks families family fun lots reunion spread
We're spread out over two blocks and there's lots of fun things. Some families make this a family reunion event. It's a feel-good kind of thing. There's something for everybody. Kent Perkins
blocks both concerning current effects hope identify learning mechanism molecular offer present processes relapse remains study treating type types underlying understood
To our knowledge, the current study is the first to identify a molecular mechanism that blocks both retrieval and reconsolidation of any type of memory. While much remains to be understood concerning the cellular processes underlying the effects of ERK in drug-stimulus associations and other types of learning and memory, the present findings offer hope for treating cue-elicited relapse in addicts. John Marshall
blocks folks histories popular scholarly
I don't read many popular histories like the ones I write. The building blocks for my research are scholarly monographs, and the inspiration for my storytelling style are folks like Chekhov. Rick Perlstein
blocks followed life series stepping stones stumbling
Life is a series of stepping stones followed with a series of stumbling blocks .... Amber Frey
building wells climbs
When I climb a building, I've been there already, and carefully planned how to start the climb as well as how to do it. Alain Robert
building-something building
...clatter of a typwriter suggests that you're actually building something. David Sedaris
building difference game games guys last tired
The only difference between tonight's game and last night's game is that 40 guys were a little more tired tonight, and the building was different, ... All I know is that if we play 82 games like this, I'm going to die. Mark Parrish
building mode postal service throughout
The Postal Service really isn't in a building mode anymore, and that's throughout the whole country. Michael Miles
building capital covers electricity except expenses improvement needs regular school
The per-pupil (funding) covers everything a school needs ? electricity, water, all the expenses a regular school has ? except it doesn't cover capital improvement or building a new school. Sen. Sakamoto
buildings hear knocked people
The people who knocked these buildings down will hear from all of us soon. Rudi Giuliani
building camden excites fits great people yards
The point, I think, is that Camden Yards really fits into that neighborhood but it has the 'wow' factor. A great new building that excites people but doesn't take away from the neighborhood. Ron Holt
building ideal market maybe point reached
The point is inventories are building over the ideal 60-day marks. They've maybe reached a point where the market is getting saturated. Bill Seltenheim
building hurricane originally planned raising work
The plaza is a culmination of about two years work designing, raising funds, and the building the plaza. Originally we had planned to do this in the fall, but because of the hurricane it was sidetracked. Chris Boone
movement reputation articles
I had a national and international reputation. I had written the history and articles. So I brought to the Trotskyist movement some international reputation. C. L. R. James
movement excited
I'm excited to be a part of the Olympic movement again. Bryan Clay
move people politics standing
The possibility is there because I feel it inside. I feel there are a lot of people in politics that are standing still and not doing enough. And there's a vacuum. Therefore, I can move in. Arnold Schwarzenegger
moved
We've also moved into Manitoba and Saskatchewan this year. Phillip Needham
movements stuff
There are debates, there are ads, and all that stuff so you're going to have movements up and down. Frank Newport
move stopped
We stopped because we didn't want to move into Kabul, Abdullah Abdullah
moved
[ Sherlock Holmes] has moved from being someone who was sociopathic, work-obsessed and slightly amoral, into being someone who has a certain degree of a private life, which is very, very private, with The Woman, or Irene Adler. Benedict Cumberbatch
movement painting illusion
I love the trick of painting. You can have the movement within the still thing, but it is completely fixed. And that illusion is constantly exciting. Cecily Brown
movement
We have to get some movement on it shortly, David Walker
ready scout shares stand support
We stand ready to support any organization that shares Scout values. David Richardson
ready road run
I want to be an actor, and I am being an actor. I'm not ready to run off on a road trip. Yet. Liane Balaban
ready tough
We have to get ready now for Plainfield South. They are another scrappy, tough team. We'll have to be ready. Jeff Bambule
ready reasons
We have so many reasons to be here tonight. I'm also ready to do some shopping! Natalie Chanin
ready-to-die not-ready ifs
If you're not ready to die, then how can you live? Charles de Lint
ready
I was embarrased, horrified and absolutely ready to jump him! Charlaine Harris
ready worry
Tomorrow? We have to go there and do it, ... Don't worry, I'll be ready for tomorrow. Mariano Rivera
ready respond sitting
We're sitting there on go, ready to respond if we have to. Cliff Lusk
ready sitting ticking time town
We're sitting on a ticking time bomb. This town is ready to ignite. Larry Southard
students sometimes poet
There's been no poet, no great poet in the history of poetry who hasn't also been a great reader of poetry. This is sometimes distressing to my students when I tell them this. Edward Hirsch
students
I've always loved being a student. Elizabeth Olsen
students hard
It's very hard to remain a student in life. Carol Kane
students significant aids
I voted for the Deficit Reduction Package with significant heartburn over the student aid provisions. Bob Inglis
students
We're going to take a look at all the qualifications that all of the students bring. Paul Kohn
student treat trying
What they're trying to do is treat them like they're not a student club. They are a student club. Kelly Shackelford
students three year
Three years ago, I had 18 students, ... and this year I have 44. Steve Gray
student students teacher
When the student is ready, the teacher appears. Likewise, when the teacher is ready, the students appear. Tom Callos
students wonder enough
One wonders at the docility of the students who evidently must be satisfied enough with the credentials to be uncaring about the lack of education. Jane Jacobs
teacher spring ignorance
Go ye, who rest so placidly upon the sacred Bard who had been young, and when he strung his harp was old, and had never seen the righteous forsaken, or his seed begging their bread; go, Teachers of content and honest pride, into the mine, the mill, the forge, the squalid depths of deepest ignorance, and uttermost abyss of man's neglect, and say can any hopeful plant spring up in air so foul that it extinguishes the soul's bright torch as fast as it is kindled! Charles Dickens
teacher thinking differences
You can't tell a woman who is called by God to teach that she cannot teach the Word of God... So I think the distinction is that there's a difference between the authority of a pastor and a Bible teacher. Charles Stanley
teacher real men
Just what should a young man or woman know to be 'in the know'? Is there, in other words, some inside information, some special taboo, some real lowdown on life and existence that most parents and teachers either don't know or won't tell? Alan Watts
teacher children life-changing
Do you know that moment when you paint a landscape as a child and, when you’re maybe under seven or something, the sky is just a blue stripe across the top of the paper? And then there’s that somewhat disappointing moment when the teacher tells you that the sky actually comes down in amongst all the branches. And it’s like life changes at that moment and becomes much more complicated and a little bit more boring, as it’s rather tedious to fill in the branches… Alan Rickman
teacher piano orchestra
I was much more interested in the orchestra than the piano, but I did become fairly proficient as a pianist and my teachers felt I had talent and wanted me to become a good concert pianist and earn my living that way. Alan Hovhaness
teacher boys trying
One of the hardest things for boys to learn is that a teacher is human. One of the hardest things for a teacher to learn is not to try and tell them. Alan Bennett
teacher cutting pro-life
I'm a conservative, pro-life governor in a state where it is really tough to be both. A state like New Jersey, with lots of Democrats, but still we cut taxes, we balanced budgets. We fought the teacher's union. Chris Christie
teacher special kind
What he's saying is that a Trump presidency will address those kind of things head on without caving into the special interests like the teachers union, which Mrs. [Hillary] Clinton has completely sold out to. Chris Christie
teacher commitment self
I am not going to make any commitments to the teachers union to do anything until they do something that's other than in their own self- interest. And everything they have done so far is in their self-interests, and that's it. Chris Christie
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton