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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
almost fully investors money rate recommend simply since work
I almost always recommend investors get fully invested, since it's better to put your money to work than to let it simply track the rate of inflation. Louis Navellier
almost badly people provided schooling
The majority of people in Angola were not provided with any kind of schooling and were completely illiterate, very badly paid, and treated almost as slaves. Louis Leakey
almost begging ceremony good people private putting script
As a teenager, in my songbook, I used to script what my lighting would be like. I used to dance in my roo;, it was like putting myself in a trance, and making myself feel good about things, almost like a private ceremony of begging people to like you. Mika
almost body goes hip hurdles knee leg move split tells trainer
I hate leg exercises. I hate one-legged squats. I hate the hurdles and the split squats. I hate all the leg exercises. I know they help me, and I'm able to move around and don't have knee problems, and my hip doesn't hurt anymore, but when my trainer tells me I have to do them, I almost feel like my body goes into convulsions. Michael Strahan
almost along broken gets good hard pushed unless writer written
Nothing good gets written without the writer suffering along the way, in my opinion. Writing should be a pleasure, but unless you feel almost broken many, many times in the journey to a novel, you haven't pushed yourself hard enough. Mohsin Hamid
almost apologetic avoiding bars based brutal change exposed films flow money people suit truth
After 'Chandni Bar' there was a shutdown of such bars in Mumbai. After 'Page 3' people started avoiding such events. 'Traffic Signal' exposed the money flow through the mafia. I'm not apologetic about the brutal truth in my films. Almost 70% of my films are based on reality, and 30% I fictionalize or change to suit my film. Madhur Bhandarkar
almost fat great percentage product
The percentage of fat in this product here is almost 50 percent fat. But it's turkey. But because it's turkey, we think we're doing a great job. Margo Rodriguez
almost extremely following line sad
We are pretty much approaching the line of an almost Serb-free Kosovo, which is an extremely sad phenomenon. One exodus is following another. Kris Janowski
almost exception few odds people talked
We've already talked to people and it's completely safe, ... And with the exception of a few odds and ends, we're almost done. Chuck D.
body damp
A demd, damp, moist, unpleasant body! Charles Dickens
body culture clock
A less 'brainy-culture' would learn to synchronise its body rhythms rather than its clocks. Alan Watts
body pieces granted
The day I take either my body or my work for granted will be the day you hear that I've smashed every inch of myself to pieces. Akshay Kumar
body
I'm thrilled with my body of work. Chris Cooper
body demand pay
Our bodies demand our attention; our bodies demand that we actually pay attention to what is going on with our lives. Chogyam Trungpa
body spirit good-things
The spirit of dance is an amazing thing. When the body and the spirit meet, it's a good thing. Chita Rivera
body needs humans
The adornment of the body is a human need. David LaChapelle
body needs materialistic
The adornment of the body is a human need. I don't see anything superficial about it unless your life becomes very materialistic. David LaChapelle
body towels pounds
I've gained a few pounds around the middle. The only lower body garments I own that still fit me comfortably are towels. Dave Barry
conveyed experience lives models pastors rich spiritual success victimized
When pastors don't have rich spiritual lives with Christ, they become victimized by other models of success - models conveyed to them by their training, by their experience in the church, or just by our culture. Dallas Willard
conveyed dreams gradually heavenly received recognized
Revelations are conveyed in a variety of ways, including, for example, dreams, visions, conversations with heavenly messengers, and inspiration. Some revelations are received immediately and intensely; some are recognized gradually and subtly. David A. Bednar
conveyed people
Basic emotions can be conveyed through anything. As long as you show people that you're human, they'll relate to it. Vince Staples
conveyed
Mr. Pompey may have told (another inmate) some of the same things he told me, to collaborate with some of the things I have already conveyed to you, Richard Peterson
conveyed decided decision erase government immediate letter spirit
Now that the government has decided to erase graffiti, things are clear. The decision will be implemented in letter and spirit and with immediate effect. The decision has been conveyed to the commission. Debasish Sen
conveyed convince father hoping ken merits met stopped sunday vancouver
He conveyed that to (co-owner) Ken Wagner. Ken stopped in Vancouver and met with Shaun and his father on Sunday morning, hoping to convince him on the merits of being a Nanaimo Clipper. Bill Bestwick
conveyed hearing people point view
Our view is that she wasn't hearing what our point was and it wasn't being conveyed to people who are. David Novak
conveyed desperate elements helped human humanity incredibly marriage reporting understand view viewers
Jeanne conveyed a human being's view of what she saw. Her reporting was incredibly solid. Her humanity was incredibly real. The marriage of those two elements helped viewers understand the desperate situation. Aaron Brown
conveyed ideas middle originally point process
This is a process that has been going on for a long time. The ideas were originally conveyed in the middle of January. At some point it has to come to a conclusion. Dennis Ross
educational keys doors
A very little key will open a very heavy door. Charles Dickens
education teaching brain
Pedantry crams our heads with learned lumber and takes out our brains to make room for it. Charles Caleb Colton
education book men
He who studies books alone will know how things ought to be, and he who studies men will know how they are. Charles Caleb Colton
education mind armor
The acquirements of science maybe termed the armor of the mind. Charles Caleb Colton
education teaching knowledge
Examinations are formidable even to the best prepared, for the greatest fool may ask more than the wisest man can answer. Charles Caleb Colton
education prayer men
An unschooled man who knows how to meditate upon the Lord has learned far more than the man with the highest education who does not know how to meditate. Charles Stanley
educational clothes giving
Our educational system in its entirety does nothing to give us any kind of material competence. In other words, we don't learn how to cook, how to make clothes, how to build houses, how to make love, or to do any of the absolutely fundamental things of life. Alan Watts
education learning buddhism
A scholar tries to learn something everyday; a student of Buddhism tries to unlearn something daily. Alan Watts
education country government
The United States government has the obligation to educate all young people in this country. Al Sharpton
enjoy
He that sympathizes in all the happiness of others, perhaps himself enjoys the safest happiness. Charles Caleb Colton
enjoy-life enjoy
I'm usually just enjoying life. Alan Jackson
enjoy higher feels
I feel that as much as I enjoy loafing, there is something higher for which to live. David McCullough
enjoy ifs
If you are in business, you are not enjoying. You are working. Carlos Slim
enjoyed films money scrap
I have enjoyed writing my own stuff, and it's been a privilege to be able to scrap some money together to be able to make films from my own scripts. Lisa Cholodenko
enjoyable guides hold maps memories offer people plan proud time variety wide
We are proud to be able to offer such a wide variety of maps and guides for people to plan their visit, as well as souvenirs that hold memories of the enjoyable time they had. Ruth Coleman
enjoying experience indoors relax scenery television
We're in a lodge. We're not in a tent. It's a way to relax at night. A little television indoors doesn't take away from my experience enjoying the scenery here. Rick Reynolds
enjoy open people secretly theater whenever
Whenever I open a movie, I go secretly to the theater and stand in the back and enjoy the moment. I laugh when people laugh, and when people cry, I laugh. Lee Byung-hun
enjoyment far job
Don't make career choices on short-term financial gain. Job satisfaction and career enjoyment are far more important. Henry Samueli
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
holy righteousness
My trust is not that I am holy, but that being unholy, he is my righteousness. Charles Spurgeon
holy-grail black frost
It [Cambridge] wasn't a holy grail in the sense that I'd never been to Cambridge. But then, when I did go, the contrast between Leeds, which was very black and sooty in those days, and Cambridge, which seemed like something out of a fairystory, in the grip of a hard frost, was just wonderful. Alan Bennett
holy sight
When we got it in sight of the boat, HOLY SMOKES! It's a big halibut. Randy Teeney
holy law lay leave order return rule sites weapons
leave the holy sites quickly, lay down their weapons and return to the rule of order and law. Ayad Allawi
holy people places priest work
To work is nothing; the king on his throne, the priest kneeling before the Holy Altar, all people in all places had to work, but no person at all need be a servant. James Stephens
holy-prophet way path
Follow the way of life, which the Holy Prophet has shown you, for verily that is the right path. Abu Bakr
holy intentions interior man pour unless until
You can pour holy oil and holy water on a thug until you have emptied buckets of both; but at the end he will be a consecrated thug, but a thug all the same unless interior intentions and a disciplined man are present. William H. O'Connell
holy line
We did Holy Grail, and I got my name up there as one of the directors. After that, I started moving more and more down the line I wanted to, which was making movies. Terry Gilliam
holy involves keeping physical renewal sabbath
Keeping the Sabbath day holy is much more than just physical rest. It involves spiritual renewal and worship. James E. Faust
life strong truth
There is nothing so strong or safe in an emergency of life as the simple truth. Charles Dickens
life saying-goodbye expectations
Life is made of ever so many partings welded together. Charles Dickens
life autism world
This is a world of action, and not moping and droning in. Charles Dickens
life moral existence
Let us be moral. Let us contemplate existence. Charles Dickens
life littles
Do all the good you can and make as little fuss about it as possible. Charles Dickens
life people astonishing
It is astonishing how much more people are interested in lengthening life than improving it. Charles Caleb Colton
life soul prison
Life is the jailer of the soul in this filthy prison, and its only deliverer is death. Charles Caleb Colton
life happiness dark
Much too oft we make life gloomy-- When happy we might be, If we gathered more of sunshine, And not dark shadows see. Charles Caleb Colton
life distance journey
Evils in the journey of life are like the hills which alarm travelers upon their road; they both appear great at a distance, but when we approach them we find that they are far less insurmountable than we had conceived. Charles Caleb Colton
mother children pride
Pride is one of the seven deadly sins; but it cannot be the pride of a mother in her children, for that is a compound of two cardinal virtues - faith and hope. Charles Dickens
mother determination father
what I want you to be - I don't mean physically but morally: you are very well physically - is a firm fellow, a fine firm fellow, with a will of your own, with resolution. with determination. with strength of character that is not to be influenced except on good reason by anybody, or by anything. That's what I want you to be. That's what your father, & your mother might both have been Charles Dickens
mother children heart
The two stand in the fast-thinning throng of victims, but they speak as if they were alone. Eye to eye, voice to voice, hand to hand, heart to heart, these two children of the Universal Mother, else so wide apart and differing, have come together on the dark highway, to repair home together and to rest in her bosom. Charles Dickens
mother sweet pain
Let the tears which fell, and the broken words which were exchanged in the long close embrace between the orphans, be sacred. A father, sister, and mother, were gained, and lost, in that one moment. Joy and grief were mingled in the cup; but there were no bitter tears: for even grief arose so softened, and clothed in such sweet and tender recollections, that it became a solemn pleasure, and lost all character of pain. Charles Dickens
mother nature garden
The evening wind made such a disturbance just now, among some tall old elm-trees at the bottom of the garden, that neither my mother nor Miss Betsey could forbear glancing that way. As the elms bent to one another, like giants who were whispering secrets, and after a few seconds of such repose, fell into a violent flurry, tossing their wild arms about, as if their late confidences were really too wicked for their peace of mind... Charles Dickens
mother nature children
"But even if he has been wicked," pursued Rose, "think how young he is; think that he may never have known a mother's love, or the comfort of a home; that ill-usage and blows, or the want of bread, may have driven him to herd with men who have forced him to guilt. Aunt, dear aunt, for mercy's sake, think of this, before you let them drag this sick child to a prison, which in any case must be the grave of all his chances of amendment." Charles Dickens
mother butterfly garden
Now I am in the garden at the back . . . a very preserve of butterflies as I remember it, with a high fence, and a gate . . . where the fruit clusters on the trees, riper and richer than fruit has ever been since, in any other garden, and where my mother gathers some in a basket while I stand by, bolting furtive gooseberries, and trying to look unnerved. Charles Dickens
mother abode wells
I am well aware that I am the 'umblest person going. . . . My mother is likewise a very 'umble person. We live in a 'umble abode. Charles Dickens
mother errors reform
If you would reform the world from its errors and vices, begin by enlisting the mothers. Charles Simmons
powers respect several
Mr. Harper said several times that he did not want to centralize, that he wanted to respect the powers of the provinces. Michel Gauthier
powers remain western
Western powers remain imprisoned by the idea that the world is a dangerous place, that it needs to be managed, and that they are called upon to do the managing. Stephen Kinzer
powers together work
I think it can. The powers that be, IMG, the ATP, need to work together more coherently. John McEnroe
powers respect several
Harper said several times that he did not want to centralize, that he wanted to respect the powers of the provinces. Michel Gauthier
powers recognize
We all are going to outplay and outperform what we do and it's up to the powers that be to recognize that and acknowledge that. Brian Kelly
powers work
powers at work about which we have no knowledge. Walter Rodgers
powers
If you devolve all the powers to the provinces, what do you have left? Buzz Hargrove
powers received selected
All I know is the powers that be selected us to be in this game. We just received the trophy. Matt Mauck
reverence-for-life ethics morality
Ethics is nothing else than reverence for life. Albert Schweitzer
reverence
What the Bible says is what God has disclosed and we want to approach this sacred text with cognitive reverence. D. A. Carson
reverence fathom reserves
Let us seek to fathom those things that are fathomable and reserve those things which are unfathomable for reverence in quietude. Johann Wolfgang von Goethe
reverence all-things
Above all things, reverence yourself. Pythagoras
reverence-for-life alive reverence
I have a deep reverence for everything that is alive, a reverence for life itself. Rajneesh
reverence ifs greater
God is not greater if you reverence Him, but you are greater if you serve Him. Saint Augustine
sexuality homosexuality form
I chose to treat the homosexuality like I would treat any other form of sexuality. Barbet Schroeder
sexuality better-off
Are you better off with him or without him? Ann Landers
sexuality limbs adolescence
The suppressed lesbian I had been carrying in me since adolescence began to stretch her limbs ... Adrienne Rich
sexuality greater
There is no sexuality that is greater or lesser than another. Jasmine Guy
sexuality homosexuality live-and-let-live
[On homosexuality:] I'm more inclined [now] to say live and let live. Anita Bryant
sexuality extraordinary
Sexuality and where it is going is an extraordinary question, for I don't see it going anywhere. It is with me, and that's it. David Bowie
sexual sinful
The only sexual act that is sinful is the one that uses or abuses. Pat Buckley
sexual totally
My character's the one that kind of initiates these sexual encounters, which to me was, like, totally foreign. Jake Gyllenhaal
sexual
All young people, regardless of their sexual orientation or gender identity, need someone who's got their back. James Lecesne
sexuality homosexuality form
I chose to treat the homosexuality like I would treat any other form of sexuality. Barbet Schroeder
sexuality better-off
Are you better off with him or without him? Ann Landers
sexuality limbs adolescence
The suppressed lesbian I had been carrying in me since adolescence began to stretch her limbs ... Adrienne Rich
sexuality greater
There is no sexuality that is greater or lesser than another. Jasmine Guy
sexuality homosexuality live-and-let-live
[On homosexuality:] I'm more inclined [now] to say live and let live. Anita Bryant
sexuality extraordinary
Sexuality and where it is going is an extraordinary question, for I don't see it going anywhere. It is with me, and that's it. David Bowie
sexuality developing my-own
For a while after the rape, I was afraid of my own sexuality, because I got raped right about the time when I started developing physically. Fiona Apple
sexuality pornography ifs
If pornography is part of your sexuality, then you have no right to your sexuality. Catharine MacKinnon
sexuality knows
All women are lesbians except those who don't know it ... Jill Johnston
wonderful hypothetical
Now everything is wonderful and hazardous and nothing's hypothetical. Alan Moore
wonderful scientist interest
I'm in this wonderful position where I can do what interests me. And whatever comes along that interests me, I do. The rest of the time I bother scientists about communicating. Alan Alda
wonder-love two people
Each of us has been designed for one of two immortal functions, as either a storyteller or as a cross-legged listener to tales of wonder, love, and daring. When we cease to tell or listen, then we no longer exist as a people. Bryce Courtenay
wonder ifs
And it's the wonders I'm after, even if I have to bleed for them. Catherynne M. Valente
wonderful used many-friends
It's wonderful to meet so many friends that I didn't used to like. Casey Stengel
wonderful cheeky
Don't let them get you down. Be cheeky. And wild. And wonderful. Astrid Lindgren
wonderful
When or if answers are found, you can be assured those answers will lead to more questions. Is the troubling or wonderful? It depends on your view of your place in nature, your place among the stars; I suppose. Bill Nye
wonder silver chairs
You see, Aslan didn't tell Pole what would happen. He only told her what to do. That fellow will be the death of us once he's up, I shouldn't wonder. But that doesn't let us off following the signs. - The Silver Chair C. S. Lewis
wonderful
Every time I read Erin Belieu work I'm pierced in that wonderful way poetry can. Cheryl Strayed