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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
country easy walks
It is not easy to walk alone in the country without musing upon something. Charles Dickens
country men climate
In all countries where nature does the most, man does the least. Charles Caleb Colton
country travel home
Those who visit foreign nations, but associate only with their own country-men, change their climate, but not their customs. They see new meridians, but the same men; and with heads as empty as their pockets, return home with traveled bodies, but untravelled minds. Charles Caleb Colton
country sadness men
In great cities men are more callous both to the happiness and the misery of others, than in the country; for they are constantly in the habit of seeing both extremes. Charles Caleb Colton
country heart simple
As the grand discordant harmony of the celestial bodies may be explained by the simple principles of gravity and impulse, so also in that more wonderful and complicated microcosm, the heart of man, all the phenomena of morals are perhaps resolvable into one single principle, the pursuit of apparent good; for although customs universally vary, yet man in all climates and countries is essentially the same. Charles Caleb Colton
country self names
The most notorious swindler has not assumed so many names as self-love, nor is so much ashamed of his own. She calls herself patriotism, when at the same time she is rejoicing at just as much calamity to her native country as will introduce herself into power, and expel her rivals. Charles Caleb Colton
country mean hands
Old Marley was as dead as a doornail. Mind! I don't mean to say that, of my own knowledge, what there is particularly dead about a doornail. I might have been inclined, myself, to regard a coffin-nail as the deadest piece of ironmongery in the trade. But the wisdom of our ancestors is in the simile; and my unhallowed hands shall not disturb it, or the Country's done for. You will therefore permit me to repeat, emphatically, that Marley was as dead as a doornail. Charles Dickens
country night men
If its individual citizens, to a man, are to be believed, it always is depressed, and always is stagnated, and always is at an alarming crisis, and never was otherwise; though as a body, they are ready to make oath upon the Evangelists, at any hour of the day or night, that it is the most thriving and prosperous of all countries on the habitable globe. Charles Dickens
country character men
Rattle me out of bed early, set me going, give me as short a time as you like to bolt my meals in, and keep me at it. Keep me always at it, and I'll keep you always at it, you keep somebody else always at it. There you are with the Whole Duty of Man in a commercial country. Charles Dickens
freedom butterfly deny
I only ask to be free. The butterflies are free. Mankind will surely not deny to Harold Skimpole what it concedes to the butterflies. Charles Dickens
freedom tyrants mind
Tyrants have not yet discovered any chains that can fetter the mind. Charles Caleb Colton
freedom water leaving
As muddy water is best cleared by leaving it alone, it could be argued that those who sit quietly and do nothing are making one of the best possible contributions to a world in turmoil. Alan Watts
freedom disappointment ego
Enlightenment is ego's ultimate disappointment. Chogyam Trungpa
freedom nice air
When you drop your unnecessary things, you finally can swoop and fly in vast space. It is so blue, so bright, and so nice, so airy and fresh. You can stretch your wings and breathe the air. You can do anything you want. You have experienced cheerfulness and joy, and finally the bliss of freedom occurs in you. Chogyam Trungpa
freedom democracy
Democracy: In which you say what you like and do what you're told. Dave Barry
freedom inquiry sake
There is no thought or situation that you can't put up against inquiry. Every thought, every person, every apparent problem is here for the sake of your freedom. Byron Katie
freedom thinking
What we think about when we are free to think about what we will – that is what we are or will soon become. Aiden Wilson Tozer
freedom-of-speech important
The freedom of speech is an important yardstick for a society's level of civilization. Ai Weiwei
greatness men mind
Great men, like comets, are eccentric in their courses, and formed to do extensive good by modes unintelligible to vulgar minds. Charles Caleb Colton
greatness deserving-it mind
Great minds had rather deserve contemporaneous applause without obtaining it, than obtain without deserving it. If it follow them it is well, but they will not deviate to follow it. Charles Caleb Colton
greatness men
In life we shall find many men that are great, and some that are good, but very few men that are both great and good. Charles Caleb Colton
greatness men too-much
Speaking generally, no man appears great to his contemporaries, for the same reason that no man is great to his servants--both know too much of him. Charles Caleb Colton
great-expectations secret tears
The secret was such an old one now, had so grown into me and become a part of myself, that I could not tear it away. Charles Dickens
great-expectations strange melancholy
So new to him," she muttered, "so old to me; so strange to him, so familiar to me; so melancholy to both of us!... Charles Dickens
great-expectations may done
But, in this separation I associate you only with the good and I will faithfully hold you to that always, for you have done far more good than harm, let me feel now what sharp distress I may. Charles Dickens
great-expectations may let-me
Let me feel now what sharp distress I may. Charles Dickens
greatness excellence littles
True greatness consists in being great in little things. Charles Simmons
hero blood race
No one knows where he who invented the plow was born, nor where he died; yet he has done more for humanity than the whole race of heroes who have drenched the earth with blood and whose deeds have been handed down with a precision proportionate only to the mischief they wrought. Charles Caleb Colton
hero tired voice
It feels wonderful to be go back to the 1940s and recreate the whole era through my clothes, voice and body language. I am tired of playing the larger-than-life hero. Akshay Kumar
hero world wonder
God is raising up His heroes and the time will come when they will appear and the world will wonder where they came from. Aiden Wilson Tozer
hero remember knows
We can be in our day what the heroes of faith were in their day - but remember at the time they didn't know they were heroes. Aiden Wilson Tozer
hero people villain
People are not born heroes or villains; they’re created by the people around them. Chris Colfer
hero thinking hunting
We are hunting the demons that haunt others. We get a smell and off we go. And you know why, Sunil? You know why we are so good at hunting the demons of others? Because we are so good, gifted even, at stalking and evading our own. But all demons hunters think that they are really heroes, and you know what all heroes need? Chris Abani
hero skills destined
...where's the skill in being a hero if you were always destined to do it? China Mieville
hero limits helping
I'd like to do something to help the worst afflicted, but I can't. It's not possible to save everybody. Even heroes have their all-too-human limits. Darren Shan
hero soul
Inside a soul, there's a hero to discover David Guetta
iraq groups done
In my judgment, based on the work that has been done to this point of the Iraq Survey Group, and in fact, that I reported to you in October, Iraq was in clear violation of the terms of U.N.Resolution 1441. David Kay
iraq september-11 enemy
The terrorist attacks of September 11th and the courageous actions of our armed forces in Afghanistan and Iraq remind us that friends of tyranny and enemies of freedom still exist Carl Levin
iraq campaigns liberation
The liberation of Iraq is a crucial advance in the campaign against terror Carl Levin
iraq world credibility
The intelligence failures with respect to Iraq were massive and have damaged our credibility around the world Carl Levin
iraq lebanon middle-east
The source of the terror in Lebanon as in Iraq is to be found in the Koran and in the despotisms of the Arab Middle East. David Horowitz
iraq body decided
When I decided to stay in Iraq, I decided to take the fear out of my body and put it into a freezer. Asne Seierstad
iraq united-states doe
Iraq does not pose an imminent threat to the United States of any of its neighboring nations. Dennis Kucinich
iraq bags scum
I would call the French scumbags, but that, of course, would be a disservice to bags filled with scum. I say we invade Iraq, then invade Chirac. Dennis Miller
iraq unfinished-business office
It's now clear that from the very moment President Bush took office, Iraq was his highest priority as unfinished business from the first Bush Administration. His agenda was clear: find a rationale to get rid of Saddam. Edward Kennedy
meetings attraction
It is scarcely possible in most places to get anyone to attend a meeting where the only attraction is God Aiden Wilson Tozer
meeting people
We want to see people come to this meeting who want to work, who want to see it happen. Randy Nixon
meet people
We're in Hollywood. I meet people like that every day. Omar Epps
meetings staff year
We staff about 4,000 meetings a year for the pharmaceutical industry. Pat Schaumann
meeting
When we have two jurisdictions, we have to have a meeting of the minds. John Lackey
meet session training
We're going to meet up and have a training session before I go. David Davies
meet needs
We're doing everything we can to meet the needs of our customers, but things are going to be kind of crowded. Tim Collins
meet
We're doing everything we can to meet that goal. Amanda Brown
meet
We're really getting into the meet of our schedule. This is really important. Robert Worthy
middle outside prevent shots struggled
We struggled to clog up the middle and prevent shots from outside the 18. Lance Lattin
middle sentences
Rabo Karabekian: I'm in the middle of a sentence. Circe Berman: Who isn't?. Kurt Vonnegut
middle-east dove making-peace
It takes more than one dove to make peace in the Middle East. Madeleine Albright
middle principal school work
When I was a middle school principal it disgusts me, some of the things I had to work through at that young age. Randy Simmons
middle nowhere rural singing songs whether
I think my songs are singing to the rural heart. It's not whether you're from a big city or the middle of nowhere in a small town. Rodney Atkins
middle ends get-involved
I get involved in the beginning, less in the middle, and very much at the end. Diane Sawyer
middle knows capable
Everyone tells us you really don't know what you're capable of till you're in the middle of it. Anthony Rapp
middle-east east middle
Syria is geographically and politically in the middle of the Middle East. Bashar al-Assad
middle points treat
We treat it no differently than a rainout in the middle of the season. We never make up a points race. Jiggs Thomason
mother children pride
Pride is one of the seven deadly sins; but it cannot be the pride of a mother in her children, for that is a compound of two cardinal virtues - faith and hope. Charles Dickens
mother determination father
what I want you to be - I don't mean physically but morally: you are very well physically - is a firm fellow, a fine firm fellow, with a will of your own, with resolution. with determination. with strength of character that is not to be influenced except on good reason by anybody, or by anything. That's what I want you to be. That's what your father, & your mother might both have been Charles Dickens
mother children heart
The two stand in the fast-thinning throng of victims, but they speak as if they were alone. Eye to eye, voice to voice, hand to hand, heart to heart, these two children of the Universal Mother, else so wide apart and differing, have come together on the dark highway, to repair home together and to rest in her bosom. Charles Dickens
mother sweet pain
Let the tears which fell, and the broken words which were exchanged in the long close embrace between the orphans, be sacred. A father, sister, and mother, were gained, and lost, in that one moment. Joy and grief were mingled in the cup; but there were no bitter tears: for even grief arose so softened, and clothed in such sweet and tender recollections, that it became a solemn pleasure, and lost all character of pain. Charles Dickens
mother nature garden
The evening wind made such a disturbance just now, among some tall old elm-trees at the bottom of the garden, that neither my mother nor Miss Betsey could forbear glancing that way. As the elms bent to one another, like giants who were whispering secrets, and after a few seconds of such repose, fell into a violent flurry, tossing their wild arms about, as if their late confidences were really too wicked for their peace of mind... Charles Dickens
mother nature children
"But even if he has been wicked," pursued Rose, "think how young he is; think that he may never have known a mother's love, or the comfort of a home; that ill-usage and blows, or the want of bread, may have driven him to herd with men who have forced him to guilt. Aunt, dear aunt, for mercy's sake, think of this, before you let them drag this sick child to a prison, which in any case must be the grave of all his chances of amendment." Charles Dickens
mother butterfly garden
Now I am in the garden at the back . . . a very preserve of butterflies as I remember it, with a high fence, and a gate . . . where the fruit clusters on the trees, riper and richer than fruit has ever been since, in any other garden, and where my mother gathers some in a basket while I stand by, bolting furtive gooseberries, and trying to look unnerved. Charles Dickens
mother abode wells
I am well aware that I am the 'umblest person going. . . . My mother is likewise a very 'umble person. We live in a 'umble abode. Charles Dickens
mother errors reform
If you would reform the world from its errors and vices, begin by enlisting the mothers. Charles Simmons
ought persons reasons records remain
Firstly, we have personnel records of persons we hired, persons we fired, reasons we fired them and so forth. These records have nothing to do with the assassination of the president and, therefore, ought to remain in the files. Louis Stokes
ought
I couldn't do that as attorney general. Why? Because they are my clients. You can't say they're not doing what they ought to be doing when you are the attorney general. Christine Gregoire
ought women
Women are the root of all evil. I ought to know. I'm Evel. Evel Knievel
ought
If we cannot agree, then at least we ought to move on. Ben Nelson
ought seldom
You just look at the world, and you see things unraveling, and you say, 'I wonder what we ought to do?' Things are seldom crystal clear. James F. Amos
ought
In a world that's smarter than it used to be and, in some ways, smarter than it ought to be, stupidity has a way of making us seem all the more human. Walter Kirn
ought suddenly suppose
At those times I got into... I suppose you call it a rut. I used to do comedy, comedy, comedy and I suddenly thought I ought to break away from this somehow. Val Guest
ought revolution revolutions-and-revolutionaries second
On the first day of a revolution he is a treasure; on the second he ought to be shot. Source Unknown
ought
She was happy, she knew she was happy, and knew she ought to be happy. Jane Austen
president doorstep
Somebody had to bring the truth to the doorstep of this president. Al Sharpton
president would-be said
When I talk about the assets, that was at the beginning of the talks. I was president then. I'm not president now. When I said it, this would be a sign of goodwill to begin the talks. Akbar Hashemi Rafsanjani
president together done
Never be easy for any president to deal with any Congress. But republicans got to work together. We got to get things done. Chris Christie
president needs allies
When the president of the United States says he's going to do something, he needs to do it. That makes not only our adversaries more emboldened. It makes our allies more nervous. Chris Christie
president united-states trump
He [Doanald Trump] had no business being president of the United States. Chris Christie
president needs world
The president needs to be a force that is trusted in the world. Chris Christie
president clinton
We didn't disqualify Hillary Clinton to be President of the United States the facts of her life and career disqualify her. Chris Christie
president generations myopic
Torturous advances won over generations can be lost by a single stroke of a myopic president's pen or a vainglorious general's sword. David Mitchell
president ambitious action
Fortunately, President Kennedy and Robert Kennedy disagreed with the estimate and chose a course of action less ambitious and aggressive than recommended by their advisers. David Kay
remembered
I'd like to be remembered as one who kept my priorities in the right order. S. Truett Cathy
remembered
When love flies it is remembered not as love but as something else. E. M. Forster
remembered
We are going to be remembered forever. That's pretty cool. Roy Diliberto
remembered
Whether I will be remembered at all, I really don't get to choose, unless I shoot someone famous. It's not really anything I have much control over. Henry Rollins
remembered skins skirt winning
Sometimes I think I'm better remembered for the Skins skirt than for winning the Players. Fred Funk
remembered
No one gets remembered for the things they didn't do Frank Turner
remembered
Some day I will be better remembered. Grover Cleveland
remembered stand
Be remembered for who you are and what you stand for. Anthony Mizzi
remembered strength
Dana will always be remembered for her passion, strength and ceaseless courage. Kathy Lewis
song writing pay
All poets pretend to write for immortality, but the whole tribe have no objection to present pay, and present praise. Lord Burleigh is not the only statesman who has thought one hundred pounds too much for a song, though sung by Spenser; although Oliver Goldsmith is the only poet who ever considered himself to have been overpaid. Charles Caleb Colton
song world this-life
And O there are days in this life, worth life and worth death. And O what a bright old song it is, that O 'tis love, 'tis love, 'tis love that makes the world go round! Charles Dickens
song blue rivers
Heaven above was blue, and earth beneath was green; the river glistened like a path of diamonds in the sun; the birds poured forth their songs from the shady trees; the lark soared high above the waving corn; and the deep buzz of insects filled the air. Charles Dickens
song remember lows
I can not sing the old songs now! It is not that I deem them low, 'Tis that I can't remember how They go. Charles Stuart Calverley
son blow destiny
When you become an instrument in God's hands as He transfers someone from the realm of darkness into the kingdom of His Son, you make a difference in the person's eternal destiny. Not only that, but Satan also receives a devastating blow. Charles Stanley
son grace tools
Thank the Lord for using each person as a tool in your life to deepen your insight into His grace and conforming you to the image of His Son. Charles Stanley
song pain men
Song of God and Son of Man, there He hangs, bearing pains unutterable, the just for the unjust, to bring us to God. Charles Spurgeon
song names heaven
Praise is the rehearsal of our eternal song. By grace we learn to sing, and in glory we continue to sing. What will some of you do when you get to heaven, if you go on grumbling all the way? Do not hope to get to heaven in that style. But now begin to bless the name of the Lord. Charles Spurgeon
song nature believe
The best thing is to go from nature's God dawn to nature; and if you once get to nature's God, and believe Him, and love Him, it is surprising how easy it is to hear music in the waves, and songs in the wild whisperings of the winds; to see God everywhere in the stones, in the rocks, in the rippling brooks, and hear Him everywhere, in the lowing of cattle, in the rolling of thunder, and in the fury of tempests. Get Christ first, put Him in the right place, and you will find Him to be the wisdom of God in your own experience. Charles Spurgeon