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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
age way young
I am not old, but my young way was never the way to age. Charles Dickens
age church body
We devote the activity of our youth to revelry and the decrepitude of our old age to repentance: and we finish the farce by bequeathing our dead bodies to the chancel, which when living, we interdicted from the church. Charles Caleb Colton
age waste excess
The excesses of our youth are drafts upon our old age. Charles Caleb Colton
age matter fairytale
In a utilitarian age, of all other times, it is a matter of grave importance that fairy tales should be respected. Charles Dickens
age pay time-is-money
I've reached an age at which I'd rather pay more for something that "just works" than roll up my sleeves, reach for a spanner, and make it work. Time is money, and the older we get the less of it we've got left. Charles Stross
age amusement serious
Pleasure, so called, is the murderer of serious thought. This is the age of excessive amusement. Everybody craves for it, like a babe for its rattle! Charles Spurgeon
agents very-good turns
I knew with Snape I was working as a double agent, as it turns out, and a very good one at that. Alan Rickman
age towns my-family
Hee Haw was probably my biggest exposure to live music at a young age, because there wasn't any live music around my town and no one in my family played instruments. Alan Jackson
age golden golden-rule
Here's my Golden Rule for a tarnished age: Be fair with others, but keep after them until they're fair with you. Alan Alda
alzheimers battle disease
Ronald Reagan's well documented final battles with Alzheimer's disease were fought with the same conviction and courage that his many public battles were fought. Bill Jenkins
alzheimer nursing patients work
She wanted to work with Alzheimer patients and she was working with Alzheimer patients in a nursing home. Ovena Hoade
alzheimers innovation cost
Most innovations, unfortunately, actually increase the net costs of the healthcare system. There's a few, particularly having to do with chronic diseases, that are an exception. If you could cure Alzheimer's, if you could avoid diabetes - those are gigantic in terms of saving money. But the incentive regime doesn't favor them. Bill Gates
alzheimer canada canadians crucial cure encourage funding great help hopefully improve life people proud quality research society someday support work
The Alzheimer Society of Canada is doing great work to help improve the quality of life of people with Alzheimer's disease, as well as funding crucial research to hopefully someday find a cure for the disease. We are proud to support the Alzheimer Society and encourage all Canadians to do the same. Ron Bertram
alzheimer boost cannot congress continue exciting federal flow funds progress research resources strong sustained unless urge
There have been many exciting new discoveries in Alzheimer research at NIH-funded facilities. But this progress cannot continue unless there is a strong and sustained flow of resources for research. I urge Congress to boost federal funds for Alzheimer's research to $1 billion. David Pierce
alzheimers comedian might
I must admit I am nervous about getting Alzheimer's. Once it hits, I might tell my best joke and never know it. Joan Rivers
alzheimers needs done
Dementia is often regarded as an embarrassing condition that should be hushed up and not spoken about. But I feel passionately that more needs to be done to raise awareness, which is why I became an ambassador for the Alzheimer's Society. Kevin Whately
alzheimers people long
Politicians nowadays treat Americans like medical orderlies treat Alzheimer's patients, telling them anything that will keep them subdued. It doesn't matter what untruths the people are fed because they will not long remember. But in politics, forgotten falsehoods almost guarantee new treachery. James Bovard
alzheimers one-day research
In Wisconsin, We're at the forefront of research that might one day bring cures for diseases like Parkinsons and Alzheimers, and we must seize its great potential. Jim Doyle
bothering-you bother ifs
If something is bothering you, keep it to yourself. David Strickland
both discovery driven east finds fossil mary since understand
With the discovery of Zinjanthropus at Olduvai Gorge in 1959, my grandmother Mary Leakey pioneered the research in East Africa with my grandfather Louis. Many more spectacular fossil finds have since been made, both in Africa and elsewhere, by many researchers driven to understand our past. Louise Leakey
both since
Wendy and I both wanted kids, but since we were pushing 40, the clock was ticking. Lisa Cholodenko
both feed suffice
I care not to debate which came first, Islamism or anti-Muslim bigotry; suffice to say that both feed into each other symbiotically. Maajid Nawaz
both direct guess project serious
There is a healthy fraternal rivalry, but nothing serious and we both have been looking for a project to do together. I guess he may direct me in a project some day. Mackenzie Astin
both country english federal issue kinds language laws learn official people practical side state
The other side said (there are) 799 federal and state laws mandating the use of English. ... We would say those kinds of laws are not at issue here. I think that English is the official language of this country in a practical sense already. And I think that most people who come here both learn English and want to learn English. Richard Cohen
both checks dressing great knows reason rooms sit sound together worse
The other reason Rufus and I are great together is that we're both really lazy. The rehearsing, the sound checks -- he's actually worse than I am, and that's something. To get us to do anything other than sit in our dressing rooms is a challenge. Who knows what will happen? Ben Folds
both potential
The potential is unbelievable with both those girls. Duncan Chase
both huge potential sales
The potential is huge for them both in sales and production. Tarun Das
breakdown
We've already got a lot of the film breakdown done, Chan Gailey
breakdown cancers cocktails dogs normal products smell
We actually don't know what the dogs are smelling. But we do know that cancers have breakdown products - cocktails of compounds - and these smell different to a dog than normal cells." () Michael McCulloch
breakdown family gone household income profoundly rates since wrong
Since the end of the 1970s, something has gone profoundly wrong in America. Inequality has soared. Educational progress slowed. Incarceration rates quintupled. Family breakdown accelerated. Median household income stagnated. Nicholas Kristof
breakdown driving
Usually it is someone driving in the breakdown lane. Maj. Crisp
breakdown father left life nervous obviously suffered three time traumatic
The first thing you should know about me is when I was three years old my mother left me and my father. And that was traumatic obviously for my father - he suffered a nervous breakdown at that time in his life. Robert Carlyle
breakdown
When you coach Russ Smith, you have a nervous breakdown on every possession. He's not from a different country. He's from a different planet. Rick Pitino
breakdown brilliant cultural days ironic
Only in the new millennium, in the waning days of ironic cultural breakdown could something like this have happened. He is now a brilliant actor. Robert Thompson
breakdown communication maybe
Maybe the communication breakdown was actually at their end up there. Craig Bellamy
breakdown city obviously
Obviously there's been a breakdown in the whole city of Kenner, Marc Johnson
compelling
We've always said we had the most compelling numbers. Richard Orr
compelling-reason guarantees constitution
The basic guarantees of our Constitution are warrants for the here and now, and unless there is an overwhelmingly compelling reason, they are to be promptly fulfilled. Arthur Goldberg
compelling man performance says sit though visual
Usually in theater, the visual repeats the verbal. The visual dwindles into decoration. But I think with my eyes. For me, the visual is not an afterthought, not an illustration of the text. If it says the same thing as the words, why look? The visual must be so compelling that a deaf man would sit though the performance fascinated. Robert Wilson
compelling profiling pushed reached themselves
'All in With Laila Ali' is educational, inspirational, compelling programming profiling individuals that have reached for the sky, pushed themselves to the limit and did things that you would think were impossible. Laila Ali
compelling thrilling
There is something enormously compelling about Fran Cutler. She is a thrilling bundle of energy and enthusiasm. Kate Reardon
compelling complete telling truth
We had a very compelling story that we were telling, and we weren't telling the complete truth. David Delainey
compelling experience faculty gain georgia opportunity platform project provides students tech unique wireless
This project provides a unique opportunity for the students and faculty at Georgia Tech to gain experience with a compelling new platform for next-generation wireless applications. Ron Hutchins
compelling evidence serious state
There is compelling evidence of serious state intervention. Peter Power
compelling-reason you-only-live-once reason
"You only live once" is also an equally compelling reason not to do something Aaron Karo
evidence cycles has-beens
There is no evidence that the business cycle has been repealed. Alan Greenspan
evidence exists full possibilities range
The possibilities could range from a full evidentiary hearing, a mini-trial, to just arguments on the evidence that exists or something in between." () Jack McConnell
evidence contrary knows
I don't know what it is I'm doing. But it's not that. Despite all evidence to the contrary. Edward Gorey
evidence circumstantial-evidence
Circumstantial evidence is evidence. Bernard Goldberg
evidence houses occupying survived
We have no evidence they have been killed in that attack. We know at least that Qusay, his son, has survived and he is occupying some houses in the Diyala area, Ahmad Chalabi
evidence hoping
We have no evidence that he is deceased right now. We are hoping for a rescue. Neil Johnson
evidence point
We have no evidence at this point that this was not an accident, Robert Francis
evidence nuclear saddam weapons
What there is now is evidence that Saddam has reinvigorated his nuclear weapons program. Richard Butler
evidence jury opportunity present saying
What we're saying is, 'Give us the opportunity to present our evidence on battering that the jury didn't hear.' Joe Margulies
genetic looking
What we're looking for is the possibility of a genetic eyewitness. John Ballantyne
genetic human
From the beginning, each human embryo has its own unique genetic identity. Robert Casey
genetic problems responses seen
We've seen responses that these genetic problems are being eliminated. Paul Souza
genetics primarily study understanding
What I am primarily is a neurogeneticist: I use genetics to study problems in neurobiology. The one problem I study primarily... understanding of the sense of touch. Martin Chalfie
genetic milk women
We don't know how much milk is too much for women with genetic predisposition. Susanna Larsson
genetic perspective strain
From a genetic perspective, there are significant strain differences in their structure. Brian Evans
genetics pure rarely truth
The truth, it is said, is rarely pure or simple, yet genetics can at times seem seductively transparent. Iain McGilchrist
genetic rare somewhat
It is somewhat of a rare genetic disease, Dorothy Moore
genetic greatest history material
He was the greatest in history and to get a look at his genetic material will be pretty amazing, Matthew Binns
principals schools teachers training
Now teachers and principals at our schools can go up there for the training because it's just amazing. Mildred Ellison
principal
I don't think the principal is doing anything radical. Kenneth Trump
principal strong teacher
It's sad, because she's an outstanding teacher and he was a very strong principal as well. Roger Fox
risks
There are big risks when you get leveraged, Hugh Johnson
risks
If you take risks and face your fate with dignity, there is nothing you can do that makes you small; if you don't take risks, there is nothing you can do that makes you grand, nothing. Nassim Nicholas Taleb
risks work
There are risks that it doesn't work and there are risks that it works. Azouz Ennifar
risks
We know the risks involved. It's very much a part of our training. Doug Pritchard
risks time
We were going to get the people. We take risks all the time firefighting, but we didn't want to get shot. Benny Gray
risks
It's just one of the risks that go with it. Jimmie Johnson
risks
These risks are uninsurable because they are not predictable, Thomas Wilson
risks whenever
and take risks whenever you think it is right. David Wallace