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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
albums wanted bluegrass
I've always wanted to make a bluegrass album. Alan Jackson
albums study excitement
And one's wandering proved as sterile and pointless as the excitement produced by a close study of pornographic albums. Bruno Schulz
album far few guys kid kinds trying
We've all kinds of kinds of hells and damns in country. But we don't have that other. We haven't progressed that far yet or degenerated. Who knows? . . . There are a few that are trying it. It's true. Some of these guys say it 500 times. I said (to Kid Rock), "how many times do you say it on an album -- 500 times? He just has that little grin. Hank Williams
album busy completed cool darker decided detroit five full jack mood nine record songs studio talking touring turned
We started off making a full album with Brendan in his studio in Detroit and had nine or 10 songs done, then he got busy with his own record and we started talking to Jack and Meg about touring together. So we decided to do something for the road, and it turned out that the five completed songs made a kind of cool record, with this dreamier, darker mood than some of our other stuff. Patrick Keeler
album anywhere reason sensible
Where should that album be? Should it be anywhere other than with the family? Is there any sensible reason for it not being with them? William Boyce
album great says speak wanna
Big Rube was on my first album and some of my mixtapes. His words are so powerful. I want to speak every word he says into existence. I wanna be a part of that! I wanna be a part of greatness. His wordplay is great to me. Nayvadius Cash
albums american-musician bury record
I don't think the record company is aware of it. Because they just bury my albums and don't release them. Les Baxter
album american-musician music
You know, they wanted to do a Broadway album and every show was kind of a bomb. There was no music at all. Les Baxter
albums feels
It feels great to have a #1 album. Billy Joel
artistic eyes gained people perk sort touchstone
When you tell people you're a playwright, their eyes sort of glaze over. But when you say you write the 'Fantastic Four' or 'Spider-Man,' they perk up. It's a touchstone that has gained more credibility as artistic expression. Roberto Aguirre-Sacasa
artistic
I'm an artistic person and a creator. I'm not a scientific. I'm not an engineer. Guy Laliberte
artistic-life artistic process
It is fatal to one's artistic life to talk about something this is in process. Denise Levertov
artistic reason
When you're playing festivals, you only get a half-hour. It's like a meat market. You don't get to be artistic. You don't get to play music. It's called a showcase for a reason. Cass McCombs
artistic charles comics visionary
We were always drawing comics as kids. My brother Charles made me draw comics. I was very much under his domination. He was actually a much stronger artistic visionary than I was. Robert Crumb
artistic enjoy extreme knowledge whether
Whether you have extreme artistic knowledge or not, it's going to be something that everyone can appreciate. Who can't enjoy pretty lights? Christine Burdick
artistic field name top
What he did in the artistic field is what a lot of Japan's top name manufacturers did in their field. James Bailey
artistic high kids percentage spanish
With the high percentage of Spanish speakers, we wanted these kids to have an artistic outlet, too. Sheri Miller
artistic bit box children dealing drama family goal gore gotten happy hits husband individual marriage movies notes outside personal pollyanna terms time weather wife
With my goal to make a family drama and also my artistic aspirations of doing things which are a bit edgy, I've gotten a really happy marriage in 'The Weather Man', ... Gore went outside the box and did something personal and artistic, but at the same time it hits all the right notes in terms of children that may be going through a divorce, or a husband and wife dealing with it in a way that's not Pollyanna or saccharine or B.S. I haven't made that many movies like it. I know I've never made a movie as individual as 'The Weather Man' in dealing with family issues. Nicolas Cage
beatles chords father guitar handed home learned music picked sheets sing time until
We always had a guitar at home, but it wasn't until I was 14 when I picked it up myself when my father handed me these sheets of music of the Beatles and some other classics. That's where I learned all the chords and learned how to play and sing at the same time. Jose Gonzalez
beatles entire listened maybe nine
When I was maybe nine years old, I listened to the entire Beatles catalogue, non-stop, for about a year, Chris Cornell
beatles covers eddie found gene rockabilly stones
When I was a kid, I found out about Eddie Cochran and Gene Vincent through the Beatles and the Stones doing covers of rockabilly songs, Brian Setzer
beatles fans millions music musician nearly reasons redundant
It's nearly redundant to enumerate the reasons The Beatles are important. There are probably different reasons why The Beatles are important to a musician like myself and to the millions of Beatles fans who just enjoy listening to the music. Todd Rundgren
beatles black heard love pink run three
Love the Kinks, Black Sabbath, Pink Floyd, and then I run out of names. Those are the three heavies. The Beatles are pretty good. You heard those guys? They're not bad. Matt Hartman
beatles boomer kennedy visceral
You're not a baby boomer if you don't have a visceral recollection of a Kennedy and a King assassination, a Beatles breakup, a U.S. defeat in Vietnam, and a Watergate. P. J. O'Rourke
beatles culture food inventive listening positive
Food culture is like listening to the Beatles - it's international, it's very positive, it's inventive and creative. Alice Waters
beatles beethoven chance funny hear met playing quite talk
It's funny, because in 1970 I met the Beatles quite by a chance at a party. It was the Beethoven bicentenary, and I was then also playing the Beethoven Sonatas. And that's all they wanted to hear about - I wanted to talk about them, and all they wanted to talk about was Beethoven. Daniel Barenboim
beatles belly cover dad family jackie mom pearls people wore
My dad was in a Beatles cover band. My mom wore Candies and belly buttons. The people in our family were very glamorous. They wore pearls like Jackie O. Azita Ghanizada
brian players talk
When you talk about big players you talk about Brian Elliott. Mike Eaves
brian confident giving line protection throw
We wanted to throw more but the line just wasn't giving Brian protection so I didn't feel confident with it. Matt Kujovsky
brian coach coming dallas hill miami san teams three win
This win was real big. Coach ( Brian Hill ) said that we have three teams coming up with Miami (April 9), Dallas and San Antonio (April 13) and we wanted to get all three teams. Dwight Howard
brian chris division either hope next won
We hope to have Chris and Brian next season. We would not have won the division without either one of them. Bruce Allen
brian counting innings
We were counting on 200 innings from Brian this year. Jim Bowden
brian committed deal united
Because when the film was first mooted, the Beatles didn't like the idea at all. In fact they wouldn't have any part in it. And when Brian had committed them, it was part of a deal he did with United Artists, I think. George Martin
brian core free lose montreal players positive retain revenue signs washington
When the organization signs core players like Brian Schneider, I think it's very important to retain them and not lose them through free agency. To be able to come into Washington and to be able to have the revenue to do some of the things we were not able to do when they were the Montreal Expos is very positive for the franchise. Jim Bowden
brian face good guard points pressure
We are not going to face a guard as good as Brian Morris. He had 34 points the first game, we wanted to pressure all over. Dan Brinkley
brian hopefully persuade wants
Tommy still wants to come to Tamworth and hopefully he can persuade Brian to let him go. Mark Cooper
direction february four industry lincoln mercury moving pleased program similar since
We are pleased to see the industry moving in this direction. Just to give you a little history, we launched a similar program enhancement four years ago. Ford, Lincoln and Mercury CPO have been teamed with MSX International since February 2002. Mark Stewart
direction hanging playing stage together
We've always been friends before we were even in a band. It's a good-natured feeling, playing together on stage every night. To us, hanging out is playing a show. We can read each other and know each other's moods, and we know the direction we're headed. But we also know nothing is set in stone. Chris Culos
direction front job quite
There are some encouraging signs. They're going in the right direction. Still, they've got quite a job in front of them. Stuart Fraser
direction negative pulling start
When you start pulling out infrastructure that's been there over 100 years, that's a negative direction to be heading. Jon Tester
direction good growing number state voters
We have a state where a growing number of voters are displeased with the direction of the state. If that's not a good set-up for a third-party candidate, I don't know what is. Tim Hibbitts
direction hooked people point whatever
We've been able to point people in the right direction and get them hooked up with locations, crews, whatever they need. Tim Clark
direction federal waiting
We're just waiting for direction from the federal level. Kelly Brown
direction moving starting
We're moving in the right direction. We're starting to get a lot of momentum. Matt Haryasz
direction hope moving
We're moving in the right direction. At this point, that's all we can hope for. Charles Turner
driving truck inns
Childbirth, as a strictly physical phenomenon, is comparable to driving a United Parcel truck through an inner tube. Dave Barry
driving force activism
Activism has always been the driving force for change. David Swanson
driving love soon together
We started driving around together as soon as we got our licenses. We love to drive. Nick Pisca
driving experience jump lost precious sudden turned upside
This sudden jump turned her driving experience upside down and her whole world upside down. She lost the most precious thing there was to her. Her intoxication had nothing to do with that. Elbert Hatchett
driving factors market nice reminder step
When you step back and put it all together, it's nice timing. It's a New Year's reminder of the geo-political factors that are driving the market higher. Mike Wittner
driving easy interstate
It's not supposed to be easy. It's not supposed to be driving down the interstate. Carl Edwards
driving girls help run
When you run with those girls every day, you can't help but get better and that is what is driving them. Tracy Harris
driving home safely
We want everyone to get home safely who may be impaired from driving for any reason. Bob Krueger
driving hurricane imagine looked loss months six
When we were first driving through the town, I was at a loss for words. It looked like the hurricane had just come through the day before we got there. I can not even imagine what it looked like six months ago. Ryanne Floyd
heart men compassion
Dead, your Majesty. Dead, my lords and gentlemen. Dead, Right Reverends and Wrong Reverends of every order. Dead, men and women, born with Heavenly compassion in your hearts. And dying thus around us every day. Charles Dickens
heart thinking broken
The broken heart. You think you will die, but you just keep living, day after day after terrible day. Charles Dickens
heart men expectations
it is a principle of his that no man who was not a true gentleman at heart, ever was, since the world began, a true gentleman in manner. He says, no varnish can hide the grain of the wood; and that the more varnish you put on, the more the grain will express itself. Charles Dickens
heart night cities
A wonderful fact to reflect upon, that every human creature is constituted to be that profound secret and mystery to every other. A solemn consideration, when I enter a great city by night, that every one of those darkly clustered houses encloses its own secret; that every room in every one of them encloses its own secret; that every beating heart in the hundreds of thousands of breasts there, is, in some of its imaginings, a secret to the heart nearest it! Charles Dickens
heart literature emotion
There are strings in the human heart that had better not be vibrated. Charles Dickens
heart soul tears
But, tears were not the things to find their way to Mr. Bumble's soul; his heart was waterproof. Charles Dickens
heart lips my-heart
I can never close my lips where I have opened my heart Charles Dickens
heart faithful world
He knew enough of the world to know that there is nothing in it better than the faithful service of the heart. Charles Dickens
heart stronger tears
Love her, love her, love her! If she favours you, love her. If she wounds you, love her. If she tears your heart to pieces – and as it gets older and stronger, it will tear deeper – love her, love her, love her! Charles Dickens
musician thieves great-music
A great musician is just a thief who doesn't get caught Buddy Rich
musician retiring blues-music
Blues musicians don't retire. They drop. Buddy Guy
musician jazz shows
I can show you that I have played with just about every jazz musician, every African musician, every blues musician. It's not like I'm cashing in on a false concept. This is what I do. Carlos Santana
musician impossible hard
It's really hard to make a living as a musician. It's almost impossible. Billy Joel
musician young pursue
When I was a young musician, the only option available to pursue secondary education in music was to attend a classical conservatory. Billy Joel
musician like-family tied
Like family, we are tied to each other. This is what all good musicians understand. Billy Joel
musician claims
I don't claim to be a musician, I didn't go to Julliard. Dick Dale
musician
I'm a musician. It's what I do! I wouldn't be too good at anything else. Chad Smith
musician financial affair
And a musician has to learn to be frugal and to carefully manage financial affairs Charlie Byrd
particular terms thinking
When you think of al-Qaeda, you are not thinking of al-Qaeda in terms of one particular country, or one particular organization. Sibel Edmonds
particular
As I said before, there are often disagreements as to what a particular set of facts mean. That is not at all unusual, and one shouldn't read into it more than is there. Robert Mueller
particular remember several
She has been in here several times before but that particular day I don't remember her. Samuel L. Jackson
particular sundance
So many features at Sundance seemed to be powered more on the director's need to be a director than any particular story. Jill Soloway
particular
I don't follow any particular periodical anymore. I use Twitter as my customized news feed. Frank Quattrone
particular
'Moby-Dick' has a remarkable way of resonating with whatever is going on in the world at that particular moment. Nathaniel Philbrick
particular
The writers and actors on 'Friends' were notoriously particular about what made it onto the air. Warren Littlefield
particular people
Most people don't know what they spend in every single area, but they know they have a problem in particular areas. Aaron Patzer
particular share terrorists
Today's terrorists do not share a particular ethnic, educational or socioeconomic background. Bennie Thompson
words-of-wisdom speech earnest
A word in earnest is as good as a speech. Charles Dickens
words-of-wisdom crowds noise
Anything that makes a noise is satisfactory to a crowd. Charles Dickens
words-of-wisdom surprise me-alone
Surprises, like misfortunes, seldom come alone. Charles Dickens
words-of-wisdom littles captains
Captain Cuttle, like all mankind, little knew how much hope had survived within him under discouragement, until he felt its death-shock. Charles Dickens
words-you-say
The words you say never live up to the words in your head. Chris Cornell
words
It was enough just to sit there without words. Louise Erdrich
words-of-wisdom causes obvious
The simplest and most obvious cause which can there be assigned for any phenomena, is probably the true one. David Hume
words-of-kindness peace-justice refuse
I will not refuse to do the something I can do. Edward Everett Hale
words-of-wisdom desire use
Do you know at this very moment you are surrounded by eternity? And do you know that you can use that eternity if you so desire? Carlos Castaneda