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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
age way young
I am not old, but my young way was never the way to age. Charles Dickens
age church body
We devote the activity of our youth to revelry and the decrepitude of our old age to repentance: and we finish the farce by bequeathing our dead bodies to the chancel, which when living, we interdicted from the church. Charles Caleb Colton
age waste excess
The excesses of our youth are drafts upon our old age. Charles Caleb Colton
age matter fairytale
In a utilitarian age, of all other times, it is a matter of grave importance that fairy tales should be respected. Charles Dickens
age pay time-is-money
I've reached an age at which I'd rather pay more for something that "just works" than roll up my sleeves, reach for a spanner, and make it work. Time is money, and the older we get the less of it we've got left. Charles Stross
age amusement serious
Pleasure, so called, is the murderer of serious thought. This is the age of excessive amusement. Everybody craves for it, like a babe for its rattle! Charles Spurgeon
agents very-good turns
I knew with Snape I was working as a double agent, as it turns out, and a very good one at that. Alan Rickman
age towns my-family
Hee Haw was probably my biggest exposure to live music at a young age, because there wasn't any live music around my town and no one in my family played instruments. Alan Jackson
age golden golden-rule
Here's my Golden Rule for a tarnished age: Be fair with others, but keep after them until they're fair with you. Alan Alda
bad-day men dc-comics
All it takes is one bad day to reduce the sanest man alive to lunacy. That's how far the world is from where I am. Just one bad day." The Joker - The Killing Joke Alan Moore
bad-day self abuse
If I was having a bad day, eating was like self-medicating. But if you abuse food, you still have to use that substance that you abuse every day. You have to learn to use it responsibly. Al Roker
bad-day giving lazy
The only bad days as a writer are the ones when you are too cowardly or too lazy to sit down at the keyboard and give it everything you have. Chris Cleave
bad-ass thinking done
Designers think everything done by someone else is awful, and that they could do it better themselves, which explains why I designed my own living room carpet, I suppose. Chris Bangle
badass agency views
It is easy to romanticize poverty, to see poor people as inherently lacking agency and will. It is easy to strip them of human dignity, to reduce them to objects of pity. This has never been clearer than in the view of Africa from the American media, in which we are shown poverty and conflicts without any context. Chimamanda Ngozi Adichie
bad-ass bayonets ass
Where the hell do you put the bayonet? Chesty Puller
bad-mood mood
When I'm in a bad mood, I don't listen. Cathy Freeman
bad-relationship mice
I have a very bad relationship with mice. Casey Affleck
bad
You know, conservatism is not a bad thing. It's not a pejorative. Michael Steele
expectations ugly helping
Moths, and all sorts of ugly creatures, hover about a lighted candle. Can the candle help it? Charles Dickens
expectations shining quality
Shining outward qualities, although they may excite first-rate expectations, are not unusually found to be the companions of second-rate abilities. Charles Caleb Colton
expectations done defying
I am hellbent on defying your expectations, at every turn, and even if you don't like what's being done, I dare you to find it uninteresting. Alan Rickman
expectations sacred looks
With a sacred expectation, I look for God in ALL of the circumstances of my day. Aiden Wilson Tozer
expectations goodness
Always God’s goodness is the ground of our expectation. Aiden Wilson Tozer
expectations firsts novel
If you read the novel, you have expectations. And, if you've seen something first, it's just hard to do. Chloe Grace Moretz
expectations being-the-best lows
If your expectations aren't to be the best, then... you know, nobody rises to low expectations. Chip Kelly
expectations assumption
All work flows from some underlying assumptions, and the content of that faith can dramatically change our expectations for our work. David Kim
expectations people trying
When you're young, you try to meet that expectation that people have of you. It can be very stressful. But with time it's become less of problem. Catherine Deneuve
happens things-happen
Everything happens for me, not to me. Byron Katie
happens ferry i-can
I can never predict what's going to happen. Bryan Ferry
happens
That’s what happens to friends, eventually. They leave you. It’s practically what they’re for. Catherynne M. Valente
happening obsessed starts
Where story comes from, I don't know. I know that I become obsessed with something. An idea, an image, a person, the way a person talks. And then something starts happening that I can't explain, and it has a lot to do with language. Dorothy Allison
happen youths
When youths take to the street, you don't know what can happen .... Julien Dray
happened known supposed until
I've known for years that you're supposed to be present. I know that thinking about what's happened or thinking about what I want is not going to get me anywhere, but until I quit doing it I'm not present. Mariel Hemingway
happened last moderate shows steady
When you take a look at what's happened in the last month, you see the same kind of pace?right on down the line. It shows a nice, steady moderate pace, which is what you want. Delos Smith
happened happens paper
It doesn't matter what odds are on paper or what's happened before. It matters what happens that moment. Holly Holm
happened justify last sit three
We're not going to sit here and try to justify what happened two or three years ago and what happened last year, Jon Gruden
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
higher rising students
We have to get students rising to that higher standard. John Winn
higher naturally raise software stocks trade
We're going to see more software acquisitions at higher valuations. Stocks naturally will trade higher when you raise the bar. Patrick Mason
higher law past quality submit
We are getting more submissions so, on the law of averages, we are going to end up with higher quality bands. Those who didn't submit in the past now know this isn't some rinky-dink festival. Bill Donabedian
higher prices
Ultimately, it will be higher prices for the consumer. Charles Holliday
higher life people
In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. S. Jay Olshansky
higher
Nobody is going to occupy a place higher than I. Alexis de Tocqueville
higher percentage trying
We're just trying to get better down there, ... We just need to get more (touchdowns). We're not going to get a touchdown every time, but we need to get a higher percentage of them. Mark Richt
obesity aspect
Obesity affects every aspect of a peoples lives, from health to relationships. Jane Velez-Mitchell
obesity serious solved
Obesity is a very serious problem. It's not going to be solved in the courtroom. Lisa Rickard
obesity easy
How easy for those who do not bulge to not overindulge! Ogden Nash
obesity fats thirty
Count no matron happy until she hath passed thirty, and hath not waxed fat. Gelett Burgess
obesity-epidemic epidemics mortality
The infant mortality rates are insanely high. The obesity epidemic is on the rise. It is all related. Kimberly Williams-Paisley
obesity-epidemic america epidemics
I couldn't open up a magazine, you couldn't read a newspaper, you couldn't turn on the TV without hearing about the obesity epidemic in America. Morgan Spurlock
obesity reflective rise seen weight
These findings are very reflective of what we see around the world. The rise in weight and obesity is being seen globally. Mary Austin
obesity-epidemic people realizing
How much obesity has to be created in a single decade for people to realize that diet has to be responsible for it? Robert Atkins
obesity traffic cures
Adding highway lanes to deal with traffic congestion is like loosening your belt to cure obesity. Lewis Mumford
patients
We've always been told that there's nothing we can do. We're told that the patients are the ones who need to complain. J. J. Johnson
patients step
Ultimately, I think the patients need to step up on this issue. Rick Colby
patients treated until
Most patients who have been treated by a rental laser don't know it until it actually happens. David Goldberg
patients
There are unquestionably some patients getting too many embryos. David Adamson
patients
We did over 200 adjustments, ... My patients really responded. Billy Carter
patients
L.A. - talk about a cruel city: Patients are forcibly removed from hospitals. Michael Moore
patients respond
She spreads her love; the patients really respond to her. Sandra Sanchez
patients room waiting
The patients that are now in the waiting room and the ones that are in ambulance stretchers can't come into their departments because there's actually no place to put them. John Ross
patients plan send week
We plan to send 25 patients a week by the end of this year. Chris Hall
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
risk superstitions currents
No worthwhile life can be lived without risks, despite current American superstitions to the contrary... Alan Watts
risk may banking
Indeed, better risk management may be the only truly necessary element of success in banking. Alan Greenspan
risk aftermath economy
History has not dealt kindly with the aftermath of protracted periods of low risk premiums. Alan Greenspan
risk debt aftermath
Any onset of increased investor caution elevates risk premiums and, as a consequence, lowers asset values and promotes the liquidation of the debt that supported higher asset prices, ... This is the reason that history has not dealt kindly with the aftermath of protracted periods of low risk premiums. Alan Greenspan
risk acting doe
The thing is doing it, that's what it's all about. Not in the results of it. After all what is a risk? It's a risk not to take risks. Otherwise, you can go stale and repeat yourself. I don't feel like a person who takes risks. Yet there's something within me that must provoke controversy because I find it wherever I go. Anybody who cares about what he does takes risks. Al Pacino
risk myopic carpet
We do not just risk repeating history if we sweep it under the carpet, we also risk being myopic about our present. Chimamanda Ngozi Adichie
risk normal anthem
There shall be a National Anthem containing incomprehensible words and a high note that normal humans cannot hit without risk of hernia. Dave Barry
risk matter laurels
When you rest on your laurels is right when you have the risk. It exists for every company, no matter how big. David Sze
risk care
I was aware of the risks I was taking, but I did'nt care. Carlos Ruiz Zafon
surgery
Without that, the surgery would not have been possible. Vonetta Flowers
surgery talking
Streamlining is one thing. Amputation surgery is another -- and that's what we're talking about here. John Walke
surgery
The surgery went pretty well. There was nothing unexpected. Terry Greene
surgery took
It took a surgery to get me here. Brian Anderson
surgery
I don't like surgery. I don't like elective surgery, I don't like surgery that you have to have. Sandra Bernhard