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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
appears appreciate chairman deeply democratic facts house letter members responding response specific written
We appreciate the chairman responding to us but we also find his response deeply disturbing. The letter appears to have been written without any investigation of the specific facts in this case. It also appears there was no consultation with the Democratic members of the House Administration Committee. Ellen Tauscher
appears both dealer depleted due emergency expect fema filling helping increase industries industry lots ordered permanent production proud provide rebuilding sales shelter small victims
We are proud to play even a small part in helping our industries provide emergency shelter for the victims of this tragedy. It appears that most of the shelters ordered by FEMA have now been produced, but we do expect to see some carryover into 2006. In addition, industry sales in 2006 may increase due both to the need to replenish dealer lots that were depleted while manufacturers diverted their production capabilities to filling FEMA orders, and the permanent rebuilding of the hurricane-stricken areas. Leigh Foreman
appears aware financial law people vigilant
We are alerting law enforcement and financial institutions and the American people to be vigilant and to be aware of anything that appears suspicious, John Ashcroft
appears bankers definitely fall fence gas housing indecision national prices sitting state year
There are definitely more bankers sitting on the fence this year when it comes to the state of the national economy. There appears to be much indecision about how things will fall out in 2006 with such important things, such as gas prices and the housing bubble, still so uncertain. John Ziegelbauer
appears british-author certain cruelty disgusting forms vice
There are certain forms in which vice appears not only monstrous, but ridiculous; the cruelty of Nero is more disgusting than that of Tiberius. Thomas Day
appears black countries ireland second sheep
There are some black sheep countries in Europe, and one of them was Ireland and it now appears that a second one may be France. Martin Selmayr
appears basic free guarantee hoped learned lessons nixon press privacy rights talking violation
We're talking about a basic violation of the Constitutional guarantee of a free press as well as a violation of the rights of privacy of American citizens. I had hoped we would have learned our lessons from the Nixon era. Sadly, it appears we have not. George Harleigh
appears bit consumers energy improvement longer october prices rebuilding
We were anticipating that we could see a little bit of an improvement in October because the rebuilding after the hurricanes appears to have started and energy prices have stabilized, but it appears that it will take a little longer for consumers to feel better about things. Gary Thayer
appears candidates clear crop current failing forward judge mainstream mark senate support touch
While Mark Dayton has made it abundantly clear how out of touch he is, it also appears the current crop of DFL Senate candidates are out of the mainstream by failing to come forward to support Judge Roberts' nomination, Ron Carey
aspect studios arrangements
I like to explore a lot of textural, arrangement aspects in the studio. David Sylvian
aspect charge components key lookout
We actors are superstitious creatures. We do all the homework, and we put all of the components together, but there's always one key aspect that we're not in charge of, really, and that's magic. You are always on the lookout for where and how that magic is going to ignite. Lorraine Toussaint
aspect cling describe people realized trying
I've realized that it's important to stop trying to think I'm any one thing. People are confused as to their identity and try to cling to one aspect of that identity to describe what they are: American, Republican, Muslim. These are really incomplete. Mohsin Hamid
aspects point sure thoughtful trip
The point here is that the (US) administration has been very thoughtful in making sure that all aspects of the trip go well, David Waller
aspect please
We are please with every aspect of our curriculum, John Brennan
aspect either game gone played second slow together
We started slow tonight. We just couldn't put every aspect of the game together in the first game. The second game we were really fighting. I thought we played more our style. It could have gone either way. Maggie Erlenbaugh
aspect heart mental season worn
We started off great. It's a long season for a freshman. We are just getting worn down. From here on out, it's got to be all heart and working on that mental aspect of the game. Ty Zabel
aspect bang biggest front information presented science
Part of what it is to be scientifically-literate, it's not simply, 'Do you know what DNA is? Or what the Big Bang is?' That's an aspect of science literacy. The biggest part of it is do you know how to think about information that's presented in front of you. Neil deGrasse Tyson
aspect external improvement passed since though visible
I see little alteration at Lyons since I formerly passed through it. Its manufactories are, nevertheless, flourishing, though less improvement than could be expected is visible in the external aspect of the place. Marguerite Gardiner
contingent fact kinds necessary opposite opposites reasoning truths
There are two kinds of truths: those of reasoning and those of fact. The truths of reasoning are necessary and their opposite is impossible; the truths of fact are contingent and their opposites are possible. Wilhelm Leibniz
contingent gas happens natural number products rolling
We have a number of new products rolling out. Some of them are contingent on what happens to natural gas prices. Joel Staff
contingent cultural emerges exposes nor theory venue
There is a new venue for theory, necessarily impure, where it emerges in and as the very event of cultural translation. This is not the displacement of theory by historicism, nor a simple historicization of theory that exposes the contingent limits of its more generalizable claims. Judith Butler
contingent
We'll see how it goes, how it feels. It's all contingent on my recovery. Ron Hirst
contingent homes offers properties withdraw
There are many sellers who have contingent offers on properties that they're having to withdraw because they're not getting their homes sold. Aaron Zapata
contingent depends foreign talking tour
We're talking to the tour now to find out our options. A lot depends on who has tour membership. But we know the foreign contingent will be a lot bigger. Kym Hougham
contingent german-philosopher kinds necessary opposite reasoning truth truths
There are also two kinds of truths: truth of reasoning and truths of fact. Truths of reasoning are necessary and their opposite is impossible; those of fact are contingent and their opposite is possible. Gottfried Leibniz
contingent decide fire
Our contribution could be contingent on what they (the fire district) decide to do. Gene Brockman
contingent talked viable
I think the Reds are our most viable alternative. We've talked to some other clubs, but those have been contingent discussions. Barry Axelrod
fuel help normal pursuing solutions
We are aggressively pursuing solutions that will help get fuel deliveries back to a more normal status, David Lemmon
fuel hard
Are you gonna fuel your faith or fuel your fear? I'm all about fueling my faith, especially when it's hard to do so. Carrie-Anne Moss
fuel increase massive seen
We have seen a massive increase in fuel prices. Martin George
fuel matter meaning producing research
We have said long before that the matter of research is not part of the negotiation, research has its own meaning and it has nothing to do with producing fuel industrially. Ali Larijani
fuel happy
We want more from the chancellor. We are not happy with the levy on fuel tax. Steve Williams
fuel talk
What they've got to do is talk about fuel efficiency. Daniel Gorrell
fuel head meeting objectives possible protecting start supply
We're getting a head start in meeting the president's objectives of protecting Americans from possible fuel supply disruptions this winter, Bill Richardson
fuel hoping instead offset passengers price raise ride
We're hoping to be able to offset the price of fuel ... by having more passengers ride ... instead of having to raise fares, Mike Rizzo
fuel understand
We know you're out there, ... We understand there's been fuel shortages. Bill White
highly regarding requests side
The other side has not responded to any of our requests regarding the abduction issue, so it is highly regrettable. Shinzo Abe
highly indiana involved job prepared speaks
We're doing a much better job in Indiana being prepared and collaborating, which speaks highly of the involved agencies. Kevin Cox
highly justices liberal marshall respect ruth testament
Liberal justices like Thurgood Marshall and Ruth Bader Ginsburg think as highly of him as someone like Clarence Thomas. I think that's a testament to the respect he enjoys. Richard Garnett
highly takes
You have to be highly intelligent to get away with a dumb joke. That takes a pretty smart fella. Tracy Morgan
highly somewhere themselves truth
I read somewhere that writers, as they get older, become more and more perfectionist. Which may be because they think more highly of themselves and they worry about their reputations. I think there's some truth to that. Tom Wolfe
highly intention music musical original outlet people pop producer record
People have always said that I could have been a highly successful pop artist, if only that were my intention. It never was. My original intention was to be a kind of behind-the-scenes participant in music, to just be a record producer and engineer. And I made a record for myself just so I could have an outlet for my musical ideas. Todd Rundgren
highly
We had not had highly pathogenic avian influenza in the U.S. for over 20 years. Dr. Coats
highly
When it was offered, I thought it was highly appropriate. Richard Brodhead
highly quite spoke
She was a quite a lady. And a leader. Everyone spoke so highly of her. Donna Jones
problem chopping horns
...the habitual dualist's solution to the problem of dualism: to solve the dilemma by chopping off one of the horns. Alan Watts
problem holy judaism
We have no problems with Jews and highly respect Judaism as a holy religion. Akbar Hashemi Rafsanjani
problem thousand right-place
As God is exalted to the right place in our lives, a thousand problems are solved all at once. Aiden Wilson Tozer
problem theological handiwork
Because we are the handiwork of God, it follows that all our problems and their solutions are theological. Aiden Wilson Tozer
problem bigs big-problems
The big problem is not whether the Bible is true. The big problem is whether it is true in you. Aiden Wilson Tozer
problem sort
We want to sort of put this out there that this is an institutional problem and not just one incident. Justin Davis
problem wells solutions
If you can properly define the problem, then you've already defined the solution as well. Chip Kidd
problem gender should
The problem with gender is that it prescribes how we should be, rather than recognising how we are. Chimamanda Ngozi Adichie
problem victim
Those who fume at their problems become their victims. David Seabury
projects interest i-can
Any project that I find encouraging that isn't attached to a studio, I can go to them, which I definitely would. You have to take an interest in what you do. Al Pacino
projects
You’ve never reacted to someone else. You project meaning onto nothing. And you react to the meaning you’ve projected Byron Katie
projects jagger
Never would I have thought that I would meet Mick Jagger, much less be working on the same project. Ato Essandoh
projects young staying-young
My system for staying young is to work a lot, to always have a project on the go. Carlos Fuentes
projects suspect worthy
While many of the projects may have been worthy of consideration, the way they were funded makes them suspect in the public's mind, Roy Cooper
project selling sure
We feel that this is a win-win for the foundation, so we need to make sure we're selling the project on all fronts. E. P. Thompson
project solo step successful
For me to do a project - I have a pretty successful solo career, so - for me to even want to do Primus, it had to be a creative step forward. Les Claypool
project
A creative project is a moving target. You never end up where you start. Evangeline Lilly
projects talking
We had been talking about doing more projects together. Barbara Jones
proving wrong
She's been proving them wrong in a lot of areas. Melissa Dover
proving
But we're the real deal. We keep proving them wrong. Marcelo Castillo
proving wireless
We look at Qualcomm as a wireless juggernaut, and it's proving it can execute, Sunil Reddy
proving tour
That we have the organization to do it. That's what this tour is about: proving there is no front-runner in this race. Alberto Martinez
proving sitting towards
We'll be working towards the things that need to be done to our sport overall. We're not sitting on our hands, we're still working at proving things that we need to do, we know that. Don Porter
proving work
Something like 'Much Ado' happens, and even 'Avengers' happens because of the years of building connections and doing the work and proving yourself. Joss Whedon
proving work
You can work together. You don't have to own one. We're proving it today. Randall Stephenson
proving-yourself playoffs prove
Whether it's in the playoffs or not, you have to keep proving yourself. Marc Bulger
rather sooner
We're insisting that it be sooner rather than later. Richard Berthelsen
rather
Like Hubie, and sometimes like Jim, I can be rather lengthy. Jim Calhoun
rather rule
made it a rule ... rather than the exception. Rudi Giuliani
rather record
I'm a lazy guy. I can't focus for too long. I'd rather hear a record that has no filler. Thomas Mars
rather work
I don't know about hiding away, but I really only like to present myself when I'm working on something - it's more my work I like to present to the world rather than myself. Kate Bush
rather
I am not into action and adventure on holiday; that doesn't really do it for me. I would much rather go and lie down. Keeley Hawes
rather stated
Mohamed stated he would rather kill only Americans. Abigail Perkins
rather strange
So I think it is rather strange that I got into ballet, something that I hadn't seen. Suzanne Farrell
rather survive taken
She was rather abrasive and difficult, but it must've taken that kind of personality to survive and to do what she did in the 1960s. Michael Messner
seems interfere
Work doesn't seem to interfere with my life. I have time for everything, even time to be alone. Carolina Herrera
seems situation stop trying
We're in a situation where we just can't stop the bleeding. We keep trying to put band-aids on the wound, but nothing seems to help. John Sacchi
seems work
When you stop thinking about something, the idea comes to you. It seems to work. Jim Rash
seems
We're going to do what we've been doing all year. It seems to be working fine. Nicole Piggott
seems commonplace
Anything seems commonplace, once explained. Arthur Conan Doyle
seems
I do feel as if... Look, I think I'm a very kind of ordinary person, and it seems to me that things that are of interest to me will probably be of interest to other people. I'm not exceptional; I don't have exceptional thoughts. Kate Grenville
seems worlds
It seems like there are two worlds out there - one that has revolved around 'Breaking Bad,' and then the one that I've been in, which just kind of observes it from afar. Todd Rundgren
seems
There's something about [cyclically] doing something over and over and over that seems to be particularly demotivating. Dan Ariely
seems ifs
I have to tell you I never in my life anticipated getting this old, this fast. It seems as if I were 25 just a few days ago. Ben Stein
sells
Everybody has to sell out at some point to make a living. Dennis Miller
selling assets process
I have some assets that over time will be worth something. I've been in the process of selling others. Bernard Ebbers
sell series
We've been able to sell more series than we had planned, but they take capital. Craig Parsons
selling soon supplies
We're getting supplies of all of these, and we're selling out as soon as we get them, Brian Lucas
selling-more goal priorities
Selling more of what you sell has nothing to do with what you sell. It has everything to do with your prospect's wants, needs, fears, goals, values and priorities. Don Cooper
selling encyclopedia right-now
Elvis is my religion. But for him, I'd be selling encyclopedias right now. Bruce Springsteen
sells
Never buy a stock immediately after a substantial rise or sell one immediately after a substantial drop. Benjamin Graham
sell
Look, as long as we can make records and sell enough so we can do some shows, that's all I want. You know what? I just want to play guitar and be in a band. Same as I always did. Chrissie Hynde
selling
It's like recycling: selling old clothes to help make new ones. Erin O'Connor
solved union worse
I was a union member in my youth as well and I went on strike, and I don't think it solved anything. It only made the situation worse for everyone involved. Michael Gove
solve using violence
Using violence isn't the only way to solve a problem. MacGyver MacGyver
solve
There is one person who can help solve 'writer's block'. His name is Mr. Johnnie Walker. Ashwin Sanghi
solve
Journalists must not be made accomplices by the secret service to solve its own problems. Hubert Burda
solve
If a person is insane or troubled, you first have to get the person to admit that they have a problem before you can solve anything. James Rosenquist
solve
My comedy isn't going to solve problems; I'm not that deep. Gary Owens
solve
(The expansion) is going to help. But it won't solve the situation. Ronaldo Myers
solve
There is no ?silver bullet' to solve this problem. Bryan Whitman
solve
We will learn together how to solve the problems of the country. Nestor Kirchner
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
using-people gay evil
One of the many evils this world has to offer is the sin of homosexuality. Satan, the enemy is using people to further his agenda to destroy the Kingdom of God and as many souls as he can. Alan Chambers
using-your-talents giving bird
Use those talents you have. You will make it. You will give joy to the world. Take this tip from nature: The woods would be a very silent place if no birds sang except those who sang best. Bernard Meltzer
using whether
I think every woman should be using a foundation, whether it's liquid or compact. Aerin Lauder
using
The only use for an atomic bomb is to keep somebody else from using one. George Wald
using
This current round of gigs, I'm just doing it using pure electronics. Tom Jenkinson
using work
When you work with chains or any kind of weapons, or just when you're using hand-to-hand combat, you are going to get hurt. Lucy Liu
using
We are using resources as if we had two planets, not one. There can be no 'plan B' because there is no 'planet B.' Ban Ki-moon
using
Basically, if I have no intention of using a service then I won't bother reverse-engineering it. Jon Johansen
using
It's interesting to play a female character who's not ever using feminine wiles to get things done. Allison Tolman