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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
benefits tasks easy
It is an easy and vulgar thing to please the mob, and not a very arduous task to astonish them; but essentially to benefit and to improve them is a work fraught with difficulty, and teeming with danger. Charles Caleb Colton
benefits might alternatives
American consumers might benefit if lenders provided greater mortgage product alternatives to the traditional fixed-rate mortgage. Alan Greenspan
benefits cash size
We can guarantee cash benefits as far out and at whatever size you like, but we cannot guarantee their purchasing power. Alan Greenspan
benefits drive efforts focused offer pleased product recognized relevant source technology tremendous value
We are pleased that yet another independent source has recognized the tremendous value of our tires. Goodyear's product development efforts have focused on an application of relevant technology - advancements that are technologically innovative, but which also offer discernable benefits to those who drive on our tires. Bob Toth
benefits action longing
We must not stint Our necessary actions in the fear To cope malicious censurers, which ever, As rav'nous fishes, do a vessel follow That is new-trimmed, but benefit no further Than vainly longing. William Shakespeare
benefits brings great people rich wealth
Wealth brings great benefits to the world. Rich people are heros. P. J. O'Rourke
benefits persons
Unless what you say benefits the other person, don't say it. Denis Waitley
benefits people sick
We have no benefits at all -- no sick leave. What most people have, we don't have it. Darrell Braden
benefits card earning elite gives maximize members nights point potential rewards towards
We want our members to be able to maximize their point earning potential. This card not only allows members to earn more Marriott Rewards points, and it also gives them many benefits such as a free-night certificate yearly, and 15 nights towards Elite status. Ed French
buses fuel performance tested transit
We've already tested the fuel in one of our transit buses and the performance was excellent, Bill Cartwright
buses cycling line misery ourselves oxford
Cycling is the only way to free ourselves from the misery of the Tube, the wall-to-wall buses that line Oxford Street, the hopelessness of even thinking about driving. Deborah Moggach
buses nearly served
We served a lot of people. Nearly 50 buses a day went out of here. Steve Wise
buses consider less percent planning
We're at less than 10 percent done with this trans (sic) planning when you consider the buses and the people. Don Day
buses consider less percent planning
We're at less than 10 percent done with this ... planning when you consider the buses and the people. Don Day
buses closely electric encourage huge including people programme promote record sums
We're investing record sums on buses and trains. We have a huge programme to encourage people to walk and cycle, and everyone up to and including the PM has been looking closely at how we can promote electric vehicles, hybrids, and other technologies. Geoff Hoon
buses charter coaches decide depends far game leave whether
We do charter buses sometimes, but it just depends on the sport and how far away the game will be. We usually leave it up to the coaches to decide on whether or not a charter bus is needed. Don Roy
buses household people watching ways
There are so many ways to do research - even watching old Ealing comedies, watching people getting on and off buses in London, looking at household interiors. Sara Sheridan
buses drivers idle morning starts until
One person comes in the morning and starts all the buses in a lot, and they idle until the drivers arrive. That can take an hour. These depots should never be in residential areas. Nancy Alderman
cars five gives performance reason ss three
The performance of all five Cobalt SS Supercharged cars this weekend, from three independent teams, gives us reason to be proud. Ken Wasmer
cars hear police providing sanctuary
We are providing a sanctuary for God's people. You don't hear sirens and police cars going up and down around here. Haan Phelps
cars grows larger level requires service traffic watch
We usually watch the traffic as it grows on the roadway. When you are tripping 14,000 cars a day you are probably at a level of service that requires a larger road. Dave McKay
cars chance focused good heat hurts night race row shows spot stay traveling
When you used to only have 10 traveling cars out here, a heat race was a chance to try something, see if it works. It's not like that anymore. You have to qualify. It's all or nothing there. You have to get out of your heat race, so it's all or nothing there. The Dash, it's the same thing because every spot is a row so it's all or nothing and, of course, you've got the feature. There is never a chance to relax, or a chance to be off one bit. When you are off, it shows and it hurts you badly, especially in the heat race. You just got to be good all night long. You have to stay focused all night, every night, all year. Jason Meyers
cars great hour mile month roger shows three tight
When you think Roger is only one mile an hour off Buddy, it shows you how tight it is up front. Having three cars here has been a great month for us. Bobby Rahal
cars driving speed typical
I'm a typical guy. Driving cars and speed are really fun. Luke Mably
cars consumers design elements fashion glory great lifted past remind terms whenever whether
Whether with furniture, fashion or cars -- whenever there are great design elements from the past that can be lifted and updated, they will be. And in terms of branding, whenever car manufacturers can remind consumers of their glory days, that always translates into profit. Mark Healy
cars common consumer educated fleet miles owned thousand type watch whether
Watch out for those cars owned by salesmen or servicemen. Any educated consumer can look at a car and tell whether it's well maintained. Twenty-to-thirty thousand miles are common (for a rental or fleet car). Look at the odometer and the type of vehicle. Douglas Love
cars compete drivers establish expected fifth grid growth improved managing prize season seeing series starting teams
We're starting our fifth season of competition, and this is the timeframe we expected to see the growth in the series. We had to establish a foothold, and we've done that. Now we're seeing more drivers and teams who want to compete in the series because we are managing the cost, and we've improved the prize payout. We expect even more cars on the grid when we start the season. Roger Bailey
city happening love prevent
We want to try and prevent this from happening again. We love our city and want it safe. Adger Ross
city ideas listen local officials proposals state willing work
We want to see the city come back, and we're willing to listen to proposals and ideas. We want to work with local and state officials to get the city back on its feet. John Payne
city creates expect friday kansas league noon orders practice problems saturday squeeze suggestion trying
The other suggestion was to play in Kansas City at noon Sunday, ... We don't expect any hurricanes here. That was considered, but the league made its decision. It creates some real problems for us with travel, and with trying to squeeze a Thursday, Friday and Saturday practice all into Thursday. But we have to do what the league orders us to do. Carl Peterson
city decree given king sat
The posts went out, being hastened by the king's commandment, and the decree was given in Shushan the palace. And the king and Haman sat down to drink; but the city Shushan was perplexed. Bible Bible
city last people sat
the people who sat comfortably in this city last week. Artur Davis
city desperate eliminate homes hurricane less philosophy point protecting spend threat time trying
The point is to eliminate that storm-surge threat with one of these plans. The philosophy of what we do during a hurricane would change. We could spend more time protecting our homes and less time trying to get out of the city in these desperate evacuations. Al Naomi
city growing rio success
We are a vibrant, growing city with a lot to offer. I think success in Rio Rancho will be success for Albuquerque. Kevin Jackson
city comedians politics
There are comedians who focus on everything that is external. They focus on politics and the news, what's going on in that city and that night. Mike Birbiglia
city community helping indiana lowest property recognized tax west
West Lafayette has been recognized as having the lowest city property tax and recognized for helping the Indiana community grow. Jan Mills
consumers energy high higher lost oil pay prices though
The persistence of high oil prices can't be lost on the Fed. Consumers have to pay for higher energy even though it's volatile. It is a real cost. David Joy
consumer positive strong
We are positive on stocks, especially those that are benefiting from very strong U.S. consumer demand. Gary Campbell
consumers expect general gentle happier housing market pickup recovery retail sales seeing stronger wealth
We are seeing a gentle recovery going on in retail sales at this stage, which I expect to get stronger going forward. The pickup in the housing market should have a general wealth effect, making consumers happier to go out and spend. James Carrick
consumer continued corporate economy slowing spending
There are continued uncertainties, ... The U.S. economy is slowing and commensurate with that is slowing consumer spending and corporate spending. Alan Ackerman
consumer growth income retail robust signs source spending suggesting wage
There are some encouraging signs in retail sales, but if you look at what the source of consumer spending is, it's really income growth, and wage growth has been lackluster, suggesting the consumer will not be robust going forward. Scott Brown
consumer education impact insurance life provide rather unbiased
We want to provide unfiltered and unbiased consumer education about the impact of what life insurance does, rather than how it works. Bob Brown
consumers huge positive revision wages
While many will be disappointed that we will not necessarily see huge upward revisions to payrolls ... a significant upward revision to wages would also be a positive development, as it suggests that consumers have more firepower than we thought. Steve Stanley
consumers customer department issues resolve seem service telephone
We've become a customer service department for some of these companies. So many consumers can't seem to resolve their issues with telephone companies. Janet Jenkins
consumers tried
We've always tried to give consumers what they want, not what we feel they need, Michael Gallelli
excellent holding hope interviews monday next
We've advertised and had some excellent applicants. We'll be holding interviews from next Monday and hope to make an appointment by the end of next week. Mike Richardson
excellent job looking oklahoma paid people
We are looking to them. Oklahoma did an excellent job getting people paid promptly. Jack Dolan
excellent girls happy overall passing toward
We started off really well. We had an excellent passing night. Toward the end of the game, we got a little lackadaisical. But overall I was really happy with the way the girls played. Trisha Williams
excellent lows gentle
Gentle and low, an excellent thing in woman. William Shakespeare
excellent pitch seem wayne
Wayne Rooney is an excellent footballer. I know he is young but when he is on the pitch he doesn't seem very young. Sven Goran
excellent hard high job kids miller rich solid strength team training weight
We have a solid team and we have high expectations. I can't tell you how hard the kids have worked, especially in the weight room. (Strength and conditioning coach) Rich Miller did an excellent job with their strength training and conditioning. Dennis Martin
excellent fact fairly fight god job resources
We've been able to do a fairly god job under the circumstances I think, in fact an excellent job under the circumstances of controlling those fires. That's just what you have to do is just be able to have the resources to get out and fight those fires. David Kemp
excellent devices acquire
It is therefore an excellent device to acquire knowledge from everybody. Baltasar Gracian
excellent hone limited prioritize resources rest serve
Working with limited resources is an excellent way to hone skills that will serve you well for the rest of your career. You will prioritize profitability from the start. Jon Oringer
fuel help normal pursuing solutions
We are aggressively pursuing solutions that will help get fuel deliveries back to a more normal status, David Lemmon
fuel hard
Are you gonna fuel your faith or fuel your fear? I'm all about fueling my faith, especially when it's hard to do so. Carrie-Anne Moss
fuel increase massive seen
We have seen a massive increase in fuel prices. Martin George
fuel matter meaning producing research
We have said long before that the matter of research is not part of the negotiation, research has its own meaning and it has nothing to do with producing fuel industrially. Ali Larijani
fuel happy
We want more from the chancellor. We are not happy with the levy on fuel tax. Steve Williams
fuel talk
What they've got to do is talk about fuel efficiency. Daniel Gorrell
fuel head meeting objectives possible protecting start supply
We're getting a head start in meeting the president's objectives of protecting Americans from possible fuel supply disruptions this winter, Bill Richardson
fuel hoping instead offset passengers price raise ride
We're hoping to be able to offset the price of fuel ... by having more passengers ride ... instead of having to raise fares, Mike Rizzo
fuel understand
We know you're out there, ... We understand there's been fuel shortages. Bill White
gmos fda citizens
The FDA has received over a million comments from citizens demanding labeling of GMOs. 90 percent of Americans agree. So, why no labeling? Dennis Kucinich
gmos sparks life-is
As we descend deeper and deeper in this region its inhabitants become more and more modified, and fewer and fewer, indicating our approach towards an abyss where life is either extinguished , or exhibits but a few sparks to mark its lingering presence. Edward Forbes
gm happy hurricane invested minds money since spreading word
Since Hurricane Katrina, people's minds have been on something else, so we're happy GM has invested a lot of money in spreading the word at the end of the month. Paul Rubin
gmos musical variation
I frequently compose out the entire metric structure of a piece in modified cyclic form, where each cyclic revolution undergoes some form of 'variation' much as if measure lengths were concrete musical 'material.' Brian Ferneyhough
gm great price reduction
The price reduction is not as great as what GM has made it out to be. They are squeezing the dealers. George Hoffer
gmos agriculture worry
GMO agriculture will probably save the world in this century. But in the developed world, where few people are haunted by the specter of famine, people are free to fetishize heirloom tomatoes and worry about the provenance of what sits on their dinner tables. Annalee Newitz
gm holes jump lots pops position whether
Whether it's a GM position or not, there are lots of different holes to fill. If the right person pops up, we're going to jump on them. Matt Silverman
gm program
One of the necessities of the restructuring program is to downsize. GM has too many plants, too many people, and too many models. David Healy
gm ready stuff workers
I'm always getting ready to leave. Some GM workers just keep their stuff in boxes. You never know. Tom Hoppe
hybrid owners stand
What hybrid owners want is to stand out. Jeff Schuster
hybrid muscles starting
We're just starting to flex our muscles in the hybrid market. Jim Cain
hybrid products
There are no other hybrid products like this in the market. Richard Mason
hybrid moved technology
Hybrid technology has moved solidly into the mainstream. Don Esmond
hybrid system whatever
Hybrid deployment will be more important to companies. Whatever can get them on a system quickly. P. Herbert
hybrid public school
We are not really a school. We are not really a public place. We are a hybrid school and artists' colony. Linda Earle
hybrid last race
That won't be our last hybrid model, ... But we're not in a race with Toyota. Ann Wright
hybrid literally minds next
We literally haven't made up our minds about what our next hybrid will be. John German
hybrids though
Even though hybrids are a solution, they're not the solution. Carlos Ghosn
light sun life-is
In the moonlight which is always sad, as the light of the sun itself is--as the light called human life is--at its coming and its going. Charles Dickens
light alcohol cleaning
Bring in the bottled lightning, a clean tumbler, and a corkscrew. Charles Dickens
light israel fire
Secrecy of design, when combined with rapidity of execution, like me column that guided Israel in the deserts, becomes the guardian pillar of light and fire to our friends, a cloud of overwhelming and impenetrable darkness to our enemies. Charles Caleb Colton
light moral sometimes
Light, whether it be material or moral, is the best reformer; for it prevents those disorders which other remedies sometimes cure, but sometimes confirm. Charles Caleb Colton
light heaven growth
Posthumous fame is a plant of tardy growth, for our body must be the seed of it; or we may liken it to a torch, which nothing but the last spark of life can light up; or we may compare it to the trumpet of the archangel, for it is blown over the dead; but unlike that awful blast, it is of earth, not of heaven, and can neither rouse nor raise us. Charles Caleb Colton
light moral materials
Light, whether it be material or moral, is the best reformer. Charles Caleb Colton
light opposites people
What connexion can there be, between the place in Lincolnshire, the house in town, the Mercury in powder, and the whereabout of Jo the outlaw with the broom, who had that distant ray of light upon him when he swept the churchyard-step? What connexion can there have been between many people in the innumerable histories of this world, who, from opposite sides of great gulfs, have, nevertheless, been very curiously brought together! Charles Dickens
light stage
Poetry makes life what lights and music do the stage. Charles Dickens
light doubt church
Doubts about the fundamentals of the gospel exist in certain churches, I am told, to a large extent. My dear friends, where there is a warm-hearted church, you do not hear of them. I never saw a fly light on a red-hot plate. Charles Spurgeon
nfl six-packs cold
Trade him for a six pack; it doesn't even have to be cold. Buddy Ryan
nfl young has-beens
Somehow, I went from being too young, to being too old. Somewhere in there I must have been just right. Bobby Bowden
nfl halos inches
There's only about 6 inches that turns that halo into a noose. Bobby Bowden
nfl coaches happens
Something has to happen that you can't coach. Bobby Bowden
nfl victory moral
I am not happy with moral victories. Those things are forgotten. Bobby Bowden
nfl excuse inspiring-football
I'm not really in the excuse business. Bill Parcells
nfl trying inspiring-football
You don't get any medal for trying something, you get medals for results. Bill Parcells
nfl sitting let-me
Sitting let me learn what the NFL is all about. Chad Pennington
nfl flying pants
Flying by the seat of your pants precedes crashing by the seat of your pants. Bill Walsh
opportunity deuces letters
Then idiots talk....of Energy. If there is a word in the dictionary under any letter from A to Z that I abominate, it is energy. It is such a conventional superstition, such parrot gabble! What the deuce!....But show me a good opportunity, show me something really worth being energetic about, and I'll show you energy. Charles Dickens
opportunity men often-is
Subtract from the great man all that he owes to opportunity, all that he owes to chance, and all that he gained by the wisdom of his friends and the folly of his enemies, and the giant will often be seen to be a pygmy. Charles Caleb Colton
opportunity female lovers
Fortune, like other females, prefers a lover to a master, and submits with impatience to control; but he that wooes her with opportunity and importunity will seldom court her in vain. Charles Caleb Colton
opportunity mind glory
The road to glory would cease to be arduous if it were trite and trodden; and great minds must be ready not only to take opportunities but to make them. Charles Caleb Colton
opportunity extremity
Our extremities are God's opportunities. Charles Spurgeon
opportunity honor denial
When facing the apparent denial of my request, God gave me the opportunity to honor him by trusting His Word. Charles Spurgeon
opportunity library today
I wouldn’t be the person I am today if it wasn’t for the opportunities the library gave me. Alan Moore
opportunity voice people
It does not do to rely too much on silent majorities, Evey, for silence is a fragile thing, one loud noise, and its gone. But the people are so cowed and disorganised. A few might take the opportunity to protest, but it'll just be a voice crying in the wilderness. Noise is relative to the silence preceding it. The more absolute the hush, the more shocking the thunderclap. Our masters have not heard the people's voice for generations, Evey and it is much, much louder than they care to remember. Alan Moore
opportunity giving people
I want to be able to open up the really good treasures of the Church and Christianity to people, and that's not going to be achieved by shouting at them to convert or they'll go to hell. It's about giving them an opportunity to reimagine Christianity. Alan Green
provided statements
Many of the statements (appeared) to have been provided to her. David DeFazio
provided
I can eat beef, provided it's minced in disguise. I couldn't eat a gammon steak. Forget it. Paul O'Grady
provided takes whatever
Whatever happens, if there are summits we will be there, provided it takes place after the funeral, Joseph Kabila
provided
I am prepared to go anywhere, provided it be forward. David Livingstone
provided sloth work
I'm an all-or-nothing guy. When I'm working, I work, work, work, work, work, and when I'm not, I'm the laziest sloth this planet has ever provided us. Al Jourgensen
provided visits
When Medicare was first enacted in 1965, it provided coverage for hospitalization, doctor visits and surgeries, but there was no coverage for prescription medications. Michael Burgess
provided racking spray strength testing types
There has been a lot of testing done on the racking strength provided by different types of spray foams, ... And the strength provided by closed-cell foams can be substantial. Tom Kenny
provided
I thought it provided a lot of justification for making the improvements. Tom Zilla
provided trends
Trends in communications and convergence provided a one-two punch. McGregor Scott
showcase trying
We were trying to think of some way to showcase the kids. Sue Finnegan
showcase
This (the film) is very much a showcase for us. Steve Roach
showcase
We really do have a lot of personality in WWE. You have to, to be in this job. You showcase a lot of personality. John Cena
showcase
I'd really like this to become a showcase for the region. Matt Butterman
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
transition bells alarms
It doesn't set off any alarm bells. As is typical with T. Rowe, no transition comes about abruptly; they tend to be planned pretty well. Bill Vaughan
transition journalism
It's perfectly possible for somebody to make the transition from politics to journalism. Brit Hume
transition rebel chaos
It seems that the rebels found the chaos of transition more difficult to accept than the tyranny they had known before. They joyfully welcomed back authority-even oppressive authority-for it was less painful for them than uncertainty. Brandon Sanderson
transition moments made
There was a moment in between, a moment flung free in the midst of the transition, when he made contact. That was the moment she would dwell on. Ann Brashares
transition
We are the transition from one education to the other. Alfred Rosenberg
transition incorporation seems
Life, it seems, is nothing if not a series of initiations, transitions, and incorporations. Alan Dundes
transition
The playoffs, that's just the way that it is. You're not going to get too many transition (baskets). Greg Buckner
transition transgender rejected
When I realised I was transgender I was so afraid of what my transition would do to everyone else in my life and how they would react to it and would I be rejected? Chaz Bono
transition work
We are in the transition state, and the inspectors will work under the NPT. Mohammad Saeedi
trucks
Without these trucks here, I don't think we would have made it. Lee Smith
trucks until
You're going to have a lot of trucks until they're done. George Ross
trucks
I just went over to where all those trucks were parked to see if they were hiring, and they were, Robert Rogers