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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
art children natural
Be natural my children. For the writer that is natural has fulfilled all the rules of art. Charles Dickens
art block food
To see the butcher slap the steak before he laid it on the block, and give his knife a sharpening, was to forget breakfast instantly. It was agreeable too - it really was - to see him cut it off so smooth and juicy. There was nothing savage in the act, although the knife was large and keen; it was a piece of art, high art; there was delicacy of touch, clearness of tone, skilful handling of the subject, fine shading. It was the triumph of mind over matter; quite. Charles Dickens
art school speech
Eloquence is the language of nature, and cannot be learned in the schools; but rhetoric is the creature of art, which he who feels least will most excel in. Charles Caleb Colton
art people dirt
Mrs Joe was a very clean housekeeper, but had an exquisite art of making her clenliness more umcomfortable and unacceptable than dirt itself. Cleanliness is next to godliness, and some people do the same by their religion. Charles Dickens
art philosophy ideas
We all draw a little and compose a little, and none of us have any idea of time or money. Charles Dickens
art prayer hate
Beware, I pray thee, of presuming that thou art saved. If thy heart be renewed, if thou shalt hate the things that thou didst once love, and love the things that thou didst once hate; if thou hast really repented; if there be a thorough change of mind in thee; if thou be born again, then hast thou reason to rejoice: but if there be no vital change, no inward godliness; if there be no love to God, no prayer, no work of the Holy Spirit, then thy saying "I am saved" is but thine own assertion, and it may delude, but it will not deliver thee. Charles Spurgeon
art children crowns
Alas, if our children lose the crown of life, it will be but a small consolation that they have won the laurels of literature or art. Charles Spurgeon
art doubt whispering
Come boldly, 'O believer, for despite the whisperings of Satan and the doubtings of thine own heart, thou art greatly beloved. Charles Spurgeon
art honesty believe
I firmly believe that the only reason why I'm on this planet, the only reason why I live, breathe, and exist is, that it's my duty to be as honest as possible in my art. Alanis Morissette
dramatic fantastic grab guys louis needs somebody terrific
There are some guys I know for a fact, like Louis C.K., who always talk about how not-great of an actor he is, and he's terrific on his show. But I know Louis would play a fantastic dramatic role in something, too. He just needs somebody to grab him and say, 'Come in here and do this.' Denis Leary
dramatic elements issues reflects time trying
'Orphans' reflects unconscious elements in myself that were, at the time, indigestible and butting up against each other in my psyche; issues I wasn't really in touch with but was trying to put into a dramatic framework. Lyle Kessler
dramatic significance acquire
A frivolous society can acquire dramatic significance only through what its frivolity destroys. Edith Wharton
dramatic money
We're making money on the freighters at the moment, but not a dramatic return. Chris Chan
dramatic provide steps
We're going to take some pretty dramatic steps to provide industry-leading safety. Ross Levinsohn
dramatic drop happy profit
We're more than happy to profit from short-term fluctuations, and we think this morning's dramatic drop is very short-term, Dan Ahrens
dramatic increase industries large seen workers
With the large increase in workers in the extractive industries in our state, we've seen a dramatic increase in drug activity. Attorney Crank
dramatic extent government lebanese news officials syrian top
very dramatic news about the extent of Syrian involvement and involvement by top officials in the Lebanese government in this assassination. John Bolton
dramatic expect headline looking market rally return strong supported total track
We're looking at the headline news, but the market is being supported by the girders of the economy, a basic, strong foundation, ... I don't expect a dramatic rally from here, but we are very much on track for a high-single-digit, low-double-digit total return for the year. Ram Kolluri
entertainment provocative entertaining
I'm part of what I consider the entertainment industry. For my photos to be entertaining, they have to be provocative and new. David LaChapelle
entertainment funniest home ourselves providing stage videos
We are providing a stage where everyone can participate and everyone can be seen. We see ourselves as a combination of America's Funniest Home Videos and Entertainment Tonight. E. Hurley
entertainment interested people providing types
We're interested in providing something for people of all types and ages. It's going to be family-friendly, and there'll be entertainment between each inning. Mike deMaine
entertainment bland entertainment-business
Generally the whole entertainment business now is bland. Eartha Kitt
entertainment television associates
I've actually gotten so I don't associate television with entertainment very much. Dick Cavett
entertainment becoming destination
YouTube is becoming much more than an entertainment destination. Chad Hurley
entertainment want lawyer
I want to be an entertainment lawyer so I'll be in the business still. Charice Pempengco
entertainment
We're going to see a lot of companies that have been portals of entertainment become producers. Kevin Spacey
entertainment generation people
We're introducing the show to a new generation of people who are getting their entertainment in many, many different arenas, Ellen Wheeler
examples words
Many times the words I say don't come out in the papers. I could have as many examples as you want. Sven Eriksson
examples forcible people six
Examples is more forcible than precept. People look at my six days in the week to see what I mean on the seventh. Robert Cecil
examples rare smooth
one of the rare examples of a smooth change. Joseph Yam
examples time younger
Obviously, we can't go back in time and look at the Trapezium when it was still forming, so we try to find younger examples in the sky. Tom Megeath
examples large people three type worthless
Now those are the two--two examples -- pimps, three. They're your third... probably the three most worthless type people in a large city. Mark Fuhrman
examples false lady time
I don't know why this lady would do it (make false statements), but there are examples of it all the time in our state, country.... R. Robinson
examples experience immigrant knew literature
I knew I had to write about Canada. I just could not find in literature any examples of the immigrant experience that I've had. Shyam Selvadurai
examples left novels situations theory
I think that novels are tools of thought. They are moral philosophy with the theory left out, with just the examples of the moral situations left standing. Jill Paton Walsh
examples recreation
He will go through some examples of different recreation centers. Jim Pryor
imagination inquiry causes
We know the effects of many things, but the cause of few; experience, therefore, is a surer guide than imagination, and inquiry than conjecture. Charles Caleb Colton
imagination directors
One longs for a director with a sense of imagination. Alan Rickman
imagination inverse
There is an inverse relationship between imagination and money. Alan Moore
imagination able bitcoin
It's a bubble. It has to have intrinsic value. You have to really stretch your imagination to infer what the intrinsic value of Bitcoin is. I haven't been able to do it. Maybe somebody else can. Alan Greenspan
imagination cooking sticks
I do not stick to rules when cooking. I rely on my imagination. Akshay Kumar
imagination god-love
Let her love God as He is in Himself, and not as her imagination says He is, and pictures Him. Aiden Wilson Tozer
imagination research life-experience
I've got research, I have my own life experience I can apply, and I have my imagination. Chris Cooper
imagination wanted
I always imagined I could be what I wanted to be. Chris Brown
imagination agents shapes
What we know about who we are comes from stories. It's the agents of our imagination who really shape who we are. Chris Abani
inspires love thoughts
Making love to my thoughts always inspires me to keep my thoughts aroused, for more inspiration. Rose Mashigo
inspires love
What inspires me? I am so inspired every day. I am inspired by thinkers. I am inspired by rebellion. I am inspired by children. I have been inspired by love. Nikki Sixx
inspires jay love loyal lucky
Stephen Colbert has such a loyal following; I don't know if it's the same with Jay Leno; he really inspires love in people, and there can be a lucky ricochet of that for some people. Lisa Hannigan
inspires magical sets theme
This is why fashion is such a magical part of our lives, for it inspires our decisions without dictating them; it sets the theme but not the limits of our aesthetic. Simon Van Booy
inspires last myriad rather reactions triggers
I think the last thing you want to do as a writer, as a storyteller, is to create indifference. I don't necessarily go out of my way to provoke, but I would much rather have a song that triggers a whole myriad of reactions than a song that inspires a shrug of the shoulder. Dan Hill
inspires money pot throw whatever
Whatever inspires us, we throw it into the pot and make our own flavor. Terrance Simien
inspires
My goal is to be a racer, and I want to be someone who inspires Americans to watch Formula One. Alexander Rossi
inspires kids life missing song
Something in life inspires me, ... I have a song on my new record, 'Visions of God,' about my kids and not missing the important moments. David Phelps
inspires york
I seem to only write New York stories because it's the only thing that inspires or interests me. Jennifer Westfeldt
media people world
We live in this world of tweeting, and social media, and anti-social media, and all the rest, so no matter what you say, there is going to be what people say is a firestorm. I don't know what a firestorm is. Al Michaels
media negative
The media loves negative spin. Chloe Sevigny
media paper levels
Today's beauty ideal, strictly enforced by the media, is a person with the same level of body fat as a paper clip. Dave Barry
media priorities focus
Here in the news media, our focus is on speed. When we get hold of some new and possibly inaccurate information, our highest priority is to get it to you, the public, before our competitors do. If the news media owned airlines, there would be a lot less concern about how many planes crashed, and a lot more concern about whose plane hit the ground first. Dave Barry
media literature brands
There are not that many new media brands you can say that about nowadays. David Talbot
media instrumental-music outlets
Instrumental music is increasingly marginalized and there's just no outlet, there's no venue for it, in terms of media. David Sanborn
media government regulation
In the U.K., the history of regulation, certainly regulation of the media, is one in which, time and again, successive governments lacked the 'bottle' to enforce the powers that were available to them. David Puttnam
media corporations west
At least in the West, politicians, corporations and media moguls can no longer take for granted their power to control the public discourse - and have it go unchallenged. David Puttnam
media places-to-go social-media
Nowadays, social media is the easiest place to go to find something. David Nail
seeing selling
We are seeing a lot of selling for euros. Brian Martin
seeing slowing sort
We're sort of seeing an orchestrated slowing of the economy. But what we're not seeing is a slamming on the brakes. Bob Schnorbus
seeing start
We're going to start seeing a lot more of these. Tom Warner
seeing signs
What we're seeing now is the first signs of stress. Ed Stansfield
seeing
You're basically the sum of all the experiences you've ever had, and they're sort of shaken up in you and reproduced in the things you create, and that includes seeing movies. Ben Affleck
seeing
Seeing through is rarely seeing into. Elizabeth Bibesco
seeing throw trial
I think a lot of what you do in acting, and for the most part singing and dancing and everything, is trial and error. It's all about just seeing what works, and if it does, to use it, and if not, to throw it away. Nick Jonas
seeing
We are just seeing more and more of it. Dan Grunfeld
seeing
We are seeing some cases. It could be life-threatening. Von Roebuck