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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
alex athletic character portraying
Portraying Alex Summers, I want to look as athletic as his character is in the comics. Lucas Till
alex blessing everyday houston player until
Until Alex got there, I think I was going to play every day, ... Hopefully, one day, I can be an everyday player again. ... But being here in Houston has been a blessing for me, there's no doubt. Mike Lamb
alex band cards family members prayer remember team tribute wants
We remember Alex and his family in our prayers. We have cards going out to the members of the pep band and our team wants to do something as a tribute to Alex in his remembrance. Dianne Nolan
alexander bell discover graham less occupied pockets received search spam
What Alexander Graham Bell thought up occupied less space than a flower vase. Now it's so small that I have to search all my pockets to discover I've received a spam text. P. J. O'Rourke
alex believe ferguson good jim manager reasons sir smith steve taken
We believe we're doing things the right way and in Steve McClaren we believe we have the manager who can deliver. There are good reasons why he was taken on by Jim Smith and Sir Alex Ferguson and why he's Sven-Goran Eriksson's No 2. Steve Gibson
alex bottle cost nice red sir sod
What Sir Alex said cost him a bottle of wine. I had a nice bottle of red to give him for his birthday, but after what he said he can sod off. Phil Gartside
alex few good high player rodriguez saw wants
Very few times do you see a player who you can say he can be as good as he wants to be. Literally. I saw Alex Rodriguez in high school, and you could say it about him. That's what I think about Carlos. Allard Baird
alex came consistent playing playoffs solid state year
Yes, Alex is playing her first year on varsity, but she's been there before. She came with us to the state playoffs every year. She's a solid midfielder consistent with her play. Jennifer Grubb
alex edge english-athlete help keeping lost wants
Yes, I do want to get back into football, I haven't lost the faith. Alex wants to help with my fitness, keeping my edge and maintaining the focus. Bryan Robson
eighth ninth
We stole one in the eighth and then we stole one in the ninth with the squeeze. It was kind of nice. Bill Masse
eighth highest indicator laboratory member nobel receive scientist staff
One indicator of Ernest Lawrence's influence is the fact that I am the eighth member of his laboratory staff to receive the highest award that can come to a scientist - the Nobel Prize. Luis Walter Alvarez
eighth fifth fourth phone seventh whenever
Whenever that phone rings, I'm always looking. I could be going in in the fifth inning or the fourth inning, or I could be going in there seventh or eighth inning. Nobody's said anything to me. I'll just be ready. Adam Wainwright
eighth good ninth seventh strength
We've always had good (closers) in the ninth inning. But the seventh and eighth has been a real strength for us this year. Eric Chavez
eighth games half high seed settle team win
We're going to need team efforts, we're going to need each other down the stretch. With 29 games to go, we've got to win more than half of those to give us a better seed in the playoffs. We don't want to settle for the eighth spot. We want to try and get as high as we can. Allen Iverson
eighth fighting fights-and-fighting game knew spot
We're fighting for the eighth spot in the playoffs, we knew how important this game was. Alexei Kovalev
eighth hell hold job knew points ranked run state team
We knew they were going to make a run at us. You hold a team that's ranked eighth in the state to 37 points in the game, that's a hell of a job defensively. Mike Quarto
eighth happened team worry
We've never been the eighth seed, obviously. It's going to be different. We're not going to worry about what happened two years ago. We're just going to worry about our team now. Brad Richards
eighth last tremendous
She's just tremendous the last eighth of a mile. She's got such a big kick. Steve Klesaris
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
freshman good leadership potential quite role seems since stepped taken time waiting year
When (Foster) was a freshman she had a good year and we've been waiting since that time for her to play up to her potential and this seems to be the year. She's taken on a leadership role with our team. It wasn't quite expected, but she's stepped into the role. Terri Cash
freshman nobody stand
When he got a rebound, nobody was going to take it away from him. For a freshman to go in and make that kind of a stand is very significant. Jim Calhoun
freshman home living period stay
When I was a freshman living in the dorms I went home a lot, but now that I live off-campus I really can't stay home for a long period of time. Desarae Garland
freshman game
Man, did the freshman come through with the game on the line. Will McKinney
freshman kids people saw three time trying younger
We're just trying new stuff. You've got to make some changes, give the young kids a chance. You saw three sophomores and a freshman out there tonight. Some of the younger kids put in a lot of time during the summer. We're shuffling people in. It's tough. Mike Wheeler
freshman great phenomenal win
She did phenomenal for anyone, but for a freshman to come in and ... win those is a great accomplishment. Tanya Chaplin
freshman seventh since three
She's a freshman with three years' experience. We've had her since seventh grade. Al Peacock
freshman good played
She played really well. That's a really good freshman they have. Jim Click
freshman letter
She lettered as a freshman, and not that many freshman letter for me. Mark LaTurner
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
grade left lighting plain school
My first day in grade school, I was plain scared. I left the comfort of my run-down house, which I loved, and went to school where it was cold, it smelled, the lighting was bad. Michael Keaton
grade impressive level moving
We're moving more than a grade level a year. That's way more impressive than anything we've done so far. Mike Davis
grade japanese kept
Sometimes I'll dress like a boy, sometimes I'll dress like a Japanese crazy teenybopper. I have clothes from the 7th grade that I've kept and still wear. Kreayshawn
grades learning light testing
We are going to know what is going on with learning in grades 3 to 8, and we are testing for that, so the light will shine. Gov. Carcieri
grade since women
Since grade school, I focused on women's clothing. Melissa McCarthy
grade greenspan seeds turn wait whether year
We really don't want to give Greenspan a grade yet. You want to wait a year or two to see whether the seeds turn to weeds. Paul Kasriel
grades university
I applied for the University of Life. Didn't get the grades. David Nicholls
grade graduating high middle relatively school student
Grade school, middle school and high school were relatively easy for me, and with little studying, I was an honor student every semester, graduating 5th in my high school class. Ferid Murad
grades mom money sell third
My mom and I would make bracelets and necklaces, and I would sell it in the first, second, and third grades because that was my lunch money. Nikki Reed
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
high junior played president schools york
I was president of the schools in junior high and high school, got a scholarship to New York University, played a little basketball, and was a celebrity. Louis Gossett, Jr.
highly regarding requests side
The other side has not responded to any of our requests regarding the abduction issue, so it is highly regrettable. Shinzo Abe
high potential profits
The potential profits are so high there's a win-at-any-cost mentality. James Browning
high models perception prices support
The perception is that it's too high end, too futuristic, but I think we will see prices and use models to support it. Mark Thompson
highest income leave north pay people simply tax
The people who pay the highest income tax are also the most mobile. They simply leave North Carolina. John Connaughton
high trying unique yorkers
We are always trying to look for unique ideas, and we wanted something new for New York. We thought that hey, it's an island, let's do something on the water...New Yorkers have pretty high expectations. John Remington
high large previous risk state
We've always been on a high state of alert. The perpetrators of the previous bombings are still very much at large and the risk is still very much with us, Marty Natalegawa
kids wells understood
Well, as a kid I did not get Shakespeare. I just never understood it. Alanis Morissette
kids winning
You'll never win anything with kids Alan Hansen
kids scientist natural
Kids are natural scientists. Alan Alda
kids mind desperate
In my own mind, I was sort of a desperate kid. Al Purdy
kids gang-members wife
Near my house in Los Angeles is a waterfall. I love to take the wife and kids, but it's also near a sketchy neighborhood. So there's a lot of gang members that hang out at the waterfall. It's like somebody took an Ansel Adams photo and then put a Cypress Hill video inside it. Al Madrigal
kids enjoyed
I went to all the Love-Ins. I took my kids. I enjoyed myself. Al Lewis
kids sure various
We want the kids to do as well as they can. There are so many opportunities (for various activities), and that's good. But, how do we make sure it's not a distraction. Brad Lancaster
kids years add
It doesn't matter how old I get, I always act like an excited five year-old kid with severe ADD and a waddle at Disneyland. Chris Colfer
kids awkward special
My life is an awkward visit from the kid's table while awaiting a History Channel special. Chris Colfer
remember foolish gentle
How gentle and tender ought we to be with others who are foolish when we remember how foolish we are ourselves Charles Spurgeon
remember lord divine
Unerring wisdom ordained your lot, and selected for you the safest and best condition. Remember this, had any other condition been better for you than the one in which you are, divine love would have put you there. You are placed by God in the most suitable circumstances. Be content with such things as you have, since the Lord has ordered all things for your good. Charles Spurgeon
remember divine conditions
Remember this, had any other condition been better for you than the one in which you are, divine love would have put you there. Charles Spurgeon
remember-you remembers-you people
Remember. You are a physician. You are not a policeman nor are you a minister of religion. You must take people as they come. Remember, too that though you will generally know more about the condition than the patient, it is the patient who has the condition and this if nothing else bestows on him or her a kind of wisdom. You have the knowledge but that does not entitle you to be superior. Knowledge makes you the servant not the master. Alan Bennett
remember ifs
If you remember the ‘90s, you weren’t there. Al Jourgensen
remember moments
You dont remember days, you remember moments Cesare Pavese
remember
I've always thought that we are what we remember, and the less we remember, the less we are. Carlos Ruiz Zafon
remember let-me-go ifs
Remember me, even if it's only in a corner and secretly. Don't let me go. Carlos Ruiz Zafon
remember forget
Not to remember 9/11, is to forget what brought it about. Cal Thomas
until worked
Until 1998, I worked in marketing at ASB bank. I loved it. Jonah Lomu
until
Divorce was illegal in Chile up until 2005 or so. Hector Tobar
until
We're going to look. We'll always look until we get that solved. Jerry Angelo
until
We're going to keep doing it until (the problem) disappears. Ed Troyer
until wait
Wait until you see what we have planned. Ruth Miller
until
I didn't have an exhibition anywhere until I was 30. My first exhibition was at 30, and then for my first show in America, I'm 50. It's kind of all right: I'm just a slow burner. Tracey Emin
until
We must not only strike the iron while it is hot, we must strike it until it is hot. Tom Sharpe
until
I started with the guitar around 12 years old but didn't learn the banjo until I was about 18 or 19. Elle King
until
She's about 40 pounds. She just sits there until I get annoyed. Miles Austin
watching
We're just watching the legislation. We're not lobbying it. We're not negotiating. Jan Jones
watching
We're just going to be watching and monitoring. John Huber
watching weight
Yeah, he's watching his weight all right. Watching it expand. James Farrior
watching
I am still watching you as well Mr. Whitey! Betha Aris
watching
I feel like I always have someone watching my back. Sandra Bullock
watching
He's a keeper. We'll be watching him for years. Alan Trammel
watching
there he is, I'm watching him, there he goes. Viggo Mortensen
watching women
I think there were a lot of women out there watching and voting, and there were a lot of men out there watching, but not voting. Stacy Keibler
watching
Man, watching Jerome all day long, he just is what he is. Willie Parker