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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
basis empower girls grow joy love move solid women
We want them to grow up and have a solid psychological and physiological basis for success. I love to move more than life, and want to empower girls and women to feel the joy of movement. Linda Shelton
basis centers certain costs developing eastern european housing limited major markets paris seeing
We are seeing certain markets where housing costs and rents are going up on a monthly basis because of limited inventory, especially in developing Eastern European markets and major centers such as London, Paris and Moscow. John Connell
basis
We are probably going to see another 75 basis points. Terence Gabriel
basis concluded customers deal dispute employees firmly gate general good gourmet hands key lies pleased sort substance transport union
We are pleased to have concluded the basis and substance of a deal with Gate Gourmet. The key to unlocking this dispute now lies firmly in the hands of Gate Gourmet and the Transport and General Workers' Union (TGWU). They must sort out their differences for the good of our customers and the employees of Gate Gourmet. Mike Street
basis benefits both bring china cooperation countries definitely enhancing fields immense people role solid stability tangible various
There are both solid basis and immense potentials for cooperation between China and Morocco. Enhancing cooperation in various fields will definitely bring tangible benefits to the people of the two countries and play an important role in facilitating world peace, stability and development. Wu Bangguo
basis bigger current favorite judging move odds points strength
We still think that the bigger 50 basis points move is the odds on favorite judging by the current strength of the euro, David Brown
basis certainly country market people region room value
We still see more value in the Asia-Pacific region than in the U.S. market, where people are still panicking over inflation. On a 15- to 20-year basis for a country like Japan, which has had years of market turmoil, there is certainly still room to run. Scott Snyder
basis beyond dot government itself move objective official public request revealed sources
Where the basis of the request comes from is that the government itself has revealed nothing about these initiatives. The objective here is to move beyond unnamed DOT sources to really make public on an official basis some of the details. David Sobel
basis determined equality exciting hard justice legal midst political politics settled shall
We are in the midst of an exciting canvass... I am working very hard in politics as well as in other matters. We are determined that Mississippi shall be settled on a basis of justice and political and legal equality. Hiram Rhodes Revels
effects great talk year
When you talk about effects of (winning that game), in any one year it doesn't have that great of an effect, John Lilly
effects found protective weekly
We found protective effects with at least weekly consumption of cruciferous vegetables, Paul Brennan
effects environment exploring history human knowledge move next ready study throughout
Throughout the history of spaceflight and the study of effects of exploring to human, space environment to human body, we have accumulated enough knowledge to be able to move over to the next step: getting ready for interplanetary missions, for interplanetary exploration. Roman Romanenko
effects extreme maybe nature poses quantum trying
The extreme weakness of quantum gravitational effects now poses some philosophical problems; maybe nature is trying to tell us something new here: maybe we should not try to quantize gravity. Richard P. Feynman
effects number side tiny
The risk of getting Hep B from a blood transfusion is a tiny number, but it's a bigger number than the risk of side effects from the vaccine. Eula Biss
effects population quality terms water
We really don't know what population effects have in terms of water quality trends. Jim Egan
effects good side sleep tired today
She's tired today because she didn't get enough sleep without the machine. That's one of the side effects you don't get a good night's sleep. Iris Chenault
effects good offered reason saw special
We did the first one as good as you can. You can't make the special effects any better. There was no reason to do it. They offered it to me years ago, and I just saw no reason to do it. Michael Douglas
effects ground pile throw walk
We are going to throw it into a big pile on the ground and everyone has to walk through it and really see the effects of what they are doing. Bogan Durr
expanding growing hoping
We're hoping it is one of those things that will never be finished. We want to keep growing and expanding to have more facilities. Robert Collins
expanding interested period since
We've been interested since day one in expanding the tour. It was just something that had to be assessed over a period of time. Bob Walsh
expanding opening
So far, we're opening no new shelters. We're just expanding where we are. Nedra Turney
expanding friendship gift openly outer palate
Plunderous is the palate I gift to you, openly I hug the universe of our friendship expanding its outer limit. Bradley Chicho
expanding general media reach strategic successful
Media General has been very successful in expanding its reach through strategic purchases. Paula Otto
expanding neighbor
What we're doing is kind of expanding upon the neighbor concept. Bill Gross
expanding family presents property stays
With the world as it now presents itself, there is something perverse, and probably dysfunctional, about a person who stays in the same house for 40 years. What about the expanding family syndrome, the school-lottery migration, the property portfolio neurosis? Have you no imagination? Iain Sinclair
expanding family health illinois kid known talked work
Here in Illinois it's known as Kid Care, and I talked about expanding it to family care. So if you work full- time, you get health care. Rahm Emanuel
expanding human monster perceive population qualities science terrifying
Here's what's terrifying about Ebola. Ebola is invisible. It's a monster without a face. With the science that we have now, we can perceive Ebola as being not one thing but as a swarm, and the swarm is moving through the human population and expanding its numbers. It has the qualities of a monster. Richard Preston
kids wells understood
Well, as a kid I did not get Shakespeare. I just never understood it. Alanis Morissette
kids winning
You'll never win anything with kids Alan Hansen
kids scientist natural
Kids are natural scientists. Alan Alda
kids mind desperate
In my own mind, I was sort of a desperate kid. Al Purdy
kids gang-members wife
Near my house in Los Angeles is a waterfall. I love to take the wife and kids, but it's also near a sketchy neighborhood. So there's a lot of gang members that hang out at the waterfall. It's like somebody took an Ansel Adams photo and then put a Cypress Hill video inside it. Al Madrigal
kids enjoyed
I went to all the Love-Ins. I took my kids. I enjoyed myself. Al Lewis
kids sure various
We want the kids to do as well as they can. There are so many opportunities (for various activities), and that's good. But, how do we make sure it's not a distraction. Brad Lancaster
kids years add
It doesn't matter how old I get, I always act like an excited five year-old kid with severe ADD and a waddle at Disneyland. Chris Colfer
kids awkward special
My life is an awkward visit from the kid's table while awaiting a History Channel special. Chris Colfer
kinds seen
We've all seen it over and over again, those kinds of plays. It's just Champ. That's what he does. Domonique Foxworth
kinds rid until valid ways
We have no idea yet how long it's going to take to get rid of it. We're working on all kinds of different ways to get rid of debris, but we won't know if any of them are valid until we see what we've got to get rid of. Jean Kelly
kinds roles vice
I think being an actor makes me a better writer and vice versa. I know the kinds of roles I would kill to play, and I try to create them for others. Katori Hall
kinds
With these kinds of horses, you just dont know, ... Shes just one we really, really wanted. John Moynihan
kinds spend time worries
There are two kinds of worries -- those you can do something about and those you can't. Don't spend any time on the latter. Duke Ellington
kinds people quiet speakers-and-speaking talk
There are two kinds of people who don't say much, those who are quiet and those who talk a lot. Source Unknown
kinds labor people women
There are two kinds of people in the labor movement: women and people who like women, Lane Kirkland
kinds therefore
There are two kinds of fools: One says, ''This is old therefore it is good.'' The other one says, ''This is new therefore it is better.'' R. Inge
kinds
There are two kinds of failures: those who thought and never did, andthose who did and never thought. Laurence J. Peter
learning enemy safe
It is always safe to learn, even from our enemies; seldom safe to venture to instruct, even our friends. Charles Caleb Colton
learning ignorance knowledge
The greater the scientist, the more he is impressed with his ignorance of reality, and the more he realizes that his laws and labels, descriptions and definitions, are the products of his own thought. They help him to use the world for purposes of his own devising rather than understand and explain it. Alan Watts
learning evolution programming
Optimization hinders evolution. Alan Perlis
learning nouns programming
Any noun can be verbed. Alan Perlis
learning thinking language
A good programming language is a conceptual universe for thinking about programming. Alan Perlis
learning thinking knowing
A language that doesn't affect the way you think about programming is not worth knowing. Alan Perlis
learning machines program
To understand a program, you must become both the machine and the program. Alan Perlis
learn offspring reason
We want them to go back to doing what they used to do, which is migrate. The reason they migrate is for food. When they don't migrate, their offspring don't learn to migrate. Bruce Barber
learn people stop tolerant
We want to stop profiling. The more that people learn about Islam, the more tolerant they become. Wissam Nasr
lines
You are in every line I have ever read. Charles Dickens
lines forget-you gremlins
I get stage fright and gremlins in my head saying: 'You're going to forget your lines'. Alan Rickman
lines born guinness
f they'd been working with Alec Guinness, for instance, they wouldn't have known they were born if they'd not towed the line! Alan Bennett
lines hobbies mental-illness
There is a very fine line between hobby and mental illness. Dave Barry
lines credit my-family
I fully credit my family for keeping me grounded and for putting me back in line whenever necessary. Camilla Belle
lines number reverse spoke swing
We spoke about a number of things from conventional swing to reverse swing and different lines and lengths. Brett Lee
lines remember moments
There's a point you get to on the stage where you're not remembering lines but living them, and you reach this pure moment which, really, is more intense than what you can achieve in life. Bill Pullman
lines input ordinary
Take the classic experiment of using ordinary feedback: just take the output of something and feed it back into the input. Those of us who do that have had really rich experiences. And it is obvious that that line of experimentation can continue. David Tudor
lines owners creator
You're kinda striding the line of what's yours and theirs. What's yours (points to us), what's mine, what's ours as creators of it and what's yours as owners. David Duchovny
marketing phrases idiot
That pompous phrase (graphic novel) was thought up by some idiot in the marketing department of DC. I prefer to call them Big Expensive Comics. Alan Moore
marketing advertising timing
Strategy and timing are the Himalayas of marketing. Everything else is the Catskills. Al Ries
marketing company ultimate
Marketing is what a company is in business to do. Marketing is a company's ultimate objective. Al Ries
marketing mind building
Marketing is not selling. Marketing is building a brand in the mind of the prospect. Al Ries
marketing cows looks
A branding program should be designed to differentiate your cow from all the other cattle on the range. Even if all the cattle on the range look pretty much alike. Al Ries
marketing world needs
All you need is the best product in the world, the most efficient production in the world and global marketing. Akio Morita
market
We still like the equities market and think the S&P 500 could potentially go through 1300 this week. Henry McVey
marketing advertising products
Marketing is what you do when your product is no good. Edwin Land
marketing coaching good-coaches
I was a pretty good coach and working with marketing was like coaching. Bernard Ebbers
productive-work people mud
I hope I don't sound like an old-fashioned stick-in-the-mud, but when I hear about people making vast fortunes without doing any productive work or contributing anything to society, my reaction is: “How can I get in on that? Dave Barry
products quarter talked
There are some big inventories out there. The new products that they have talked about aren't out for another quarter or so. So it's probably going to be more of the same for some time. Bob Turner
products
It is necessary that I am viewed as a product. I am a product. Ayumi Hamasaki
production
We're getting production from different people. They're working well as a team. Ed Miller
product ready search serious
We're ready to compete. We're very serious about this. Search evolves. We have a product that I think is part of that. Barry Diller
products putting quality shelves sure
We want to make sure we're only putting safe, quality products on our shelves for our customers. Karen Burk
product
The product is out there. It's not necessarily right, and it's not necessarily wrong. It's just the idea that was generated. Matt Flynn
production recording step
The production and recording is a big step up. Grayson White
productive-life people good-relationship
Psychology, unlike chemistry, unlike algebra, unlike literature, is an owner's manual for your own mind. It's a guide to life. What could be more important than grounding young people in the scientific information that they need to live happy, healthy, productive lives? To have good relationships? Daniel Goldstein
products quarter talked
There are some big inventories out there. The new products that they have talked about aren't out for another quarter or so. So it's probably going to be more of the same for some time. Bob Turner
products
It is necessary that I am viewed as a product. I am a product. Ayumi Hamasaki
products putting quality shelves sure
We want to make sure we're only putting safe, quality products on our shelves for our customers. Karen Burk
products
We got to this point by constantly perfecting our products. Connie Sellecca
products
one of the better products we've launched in a long time. Jerry Yang
products shipping uncertain
I am uncertain about shipping our products on time. Fazlul Haque
products showcase
Basically, we do it to showcase our products to celebrities. Deanna Anderson
products providers sell service unless
More and more of the products are going to become 'carrier Ethernet,' because manufacturers aren't going to be able to sell them to service providers unless they have all these features. Michael Howard
products
You have to be a product of the product. Anthony Powell
research copying stealing
Copying one person is stealing. Copying ten is research. Chet Atkins
research just-being producers
But I'm a historian. I wasn't interested in just being a producer, I was interested in doing research and presenting that research to a general public Bernice Johnson Reagon
research fields modern
Never before in the history of the modern research university have entire departments and fields been devoted to purely ideological pursuits. David Horowitz
research sociopath psychopath
I'm a high-functioning sociopath, do your research. Benedict Cumberbatch
research
I don't research anything. Derek Bailey
research can-do
Do not do anything that anyone else can do readily. Edwin Land
research conducting finished
One must stop conducting research before one has finished. Otherwise, one will never stop and never finish. Barbara Tuchman
research sociopath psychopath
I'm not a psychopath, I'm a fully functioning sociopath. Do your research. Arthur Conan Doyle
research world body
I shall not cease learning while I live, nor when I arrive in the spirit-world… and when I again receive my body, I shall …still continue my researches Brigham Young
saying-less balance would-be
There are many who say more than the truth on some occasions, and balance the account with their consciences by saying less than the truth on others. But the fact is that they are in both instances as fraudulant as he would be that exacted more than his due from his debtors, and paid less than their due to his creditors. Charles Caleb Colton
saying waiting
What they're saying is the conventional firms are waiting too long, Raymond James
saying-and-doing quarrels poor-richard
Saying and Doing, have quarrel'd and parted. Benjamin Franklin
saying teachers
We're just saying we want him to stay. He's saying he doesn't want any more than the teachers get. Tom Ferguson
saying technology until
We're just saying 'time out' to technology until the new year. Burke Stinson
saying wait watch wish
We're getting a lot of e-mails saying they wish they could watch curling more often. They can't wait for Vancouver. Cassie Johnson
saying skirt
The sneaker heels thing is a myth. They were saying, 'They're like sneakers.' No, they're like heels is what they're like. That's like saying a denim skirt is like jeans. It's not. Anna Kendrick
saying-no offensive said
Stop saying no offense,” I said, “when you say offensive things. It’s not a free pass. Daniel Handler
saying seen treasury
We've seen this movie before. What Treasury is saying is pretty much of a rerun of what it said back in May. Frank Vargo
seems interfere
Work doesn't seem to interfere with my life. I have time for everything, even time to be alone. Carolina Herrera
seems situation stop trying
We're in a situation where we just can't stop the bleeding. We keep trying to put band-aids on the wound, but nothing seems to help. John Sacchi
seems work
When you stop thinking about something, the idea comes to you. It seems to work. Jim Rash
seems
We're going to do what we've been doing all year. It seems to be working fine. Nicole Piggott
seems commonplace
Anything seems commonplace, once explained. Arthur Conan Doyle
seem
We're getting better. We just can't seem to get over the hump. Larry Mikesell
seem time
We haven't had crime writers, and for a long time in the Republic, we didn't seem to have a crime problem as such. Ken Bruen
seemed tries whereas work
Ulster seemed to get their tries effortlessly whereas we had to work for ours. Todd Blackadder
seems
I do feel as if... Look, I think I'm a very kind of ordinary person, and it seems to me that things that are of interest to me will probably be of interest to other people. I'm not exceptional; I don't have exceptional thoughts. Kate Grenville