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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
alienate blue congress plan red states talk tax votes
When you talk about a tax plan that has to make it through Congress, you can't alienate the blue states, because you need a lot of red votes in blue states to get it passed. Joseph Thorndike
aliens aliens-movie linen
Stop your grinnin and drop your linen Bill Paxton
alien europe followed illegal law means mexicans needs people saying
What we're saying is the law needs to be applied. The law needs to be followed and that means the law for everyone, not just the illegal alien Mexicans but people who are here illegally from Europe and from around the world. Rick Oltman
aliens affair should
He who doesn't know how to be a servant should never be allowed to be a master; the interests of public life are alien to anyone who is unable to enjoy others' successes, and such a person should never be entrusted with public affairs. Anton Chekhov
alien barriers close coming conflicts created emotions ended familiar home invisible isolation people personal propel reach setting songs tough toward
We experienced a deconstruction of our personal lives. Coming home to a familiar setting and being alien to it created a sense of isolation from the people we're close to. There were all these invisible barriers that were tough to reach through. So we ended up with songs like 'Alone, Jealous, and Stoned,' about how our emotions propel us toward these conflicts and away from the people we love. Brandon Curtis
alien doctor might state threshold
With the state of the world today, an alien intervention might be just what the doctor ordered. ... Threshold Brent Spiner
alien beyond bizarre civilization depends future mingle planet within
There are many bizarre alien things at beyond and within the planet earth. The future of our civilization really depends on our willingness to mingle with them. Toba Beta
alienated expect given good interact mainstream parallel people sent separate square time trouble value
There are people so alienated from the mainstream of American culture that it's like a parallel universe. They don't expect anything but trouble from the square world. Every time they interact with that world, they're given a ticket, sent to jail, drafted. It's never good. So they live by a separate value system. Daniel Woodrell
alienation concerned decline democratic hostility increase led politics public rapid recent seen tone
I'm very concerned about the tone of politics in recent years. We've seen a decline in civility and bipartisanship, and a rapid increase in hostility between those who have differing opinions. I think this has led to the alienation of the public in governance, which jeopardizes democratic participation. Kyrsten Sinema
animal safety giving
Subtlety will sometimes give safety, no less than strength; and minuteness has sometimes escaped, where magnitude would have been crushed. The little animal that kills the boa is formidable chiefly from its insignificance, which is incompressible by the folds of its antagonist. Charles Caleb Colton
animal mind facts
You can only form the minds of reasoning animals upon Facts: nothing else will ever be of any service to them. Stick to Facts, sir! Charles Dickens
animal lions sulky
Quadruped lions are said to be savage, only when they are hungry; biped lions are rarely sulky longer than when their appetite for distinction remains unappeased. Charles Dickens
animal lust use
...the whole universe is through and through the playing of love in every shade of the word's use, from animal lust to divine charity. Alan Watts
animal envy simplicity
At times almost all of us envy the animals. They suffer and die, but do not seem to make a "problem" of it. Alan Watts
animal technology vegetables
"It is essential to understand this point thoroughly: that the thing-in-itself, whether animal, vegetable, or mineral, is not only unknowable-it does not exist. This is important not only for sanity and peace of mind, but also for the most "practical" reasons of economics, politics, and technology.. This is not to say only that things exist in relation to one another, but that what we call "things" are no more than glimpses of a unified process. Certainly, this process has distinct features which catch our attention, but we must remember that distinction is not separation." Alan Watts
animal acting kind
I'm very aware that when one is acting in the theater, you do become kind of animal about it. And you're reliant on instincts rather than tact a lot of the time. Alan Rickman
animal rocks rock-n-roll
Rock n Roll Animal, the live album, is one of the greatest live albums out there. It was a huge influence on me. Al Jourgensen
animal essence abuse
The abuse of a harmless thing is the essence of sin. Aiden Wilson Tozer
believe book writing
No men deserve the title of infidels so little as those to whom it has been usually applied; let any of those who renounce Christianity, write fairly down in a book all the absurdities that they believe instead of it, and they will find that it requires more faith to reject Christianity than to embrace it. Charles Caleb Colton
believe self denial
Forgiveness, that noblest of all self-denial, is a virtue which he alone who can practise in himself can willingly believe in another. Charles Caleb Colton
believe half literature
In religion as in politics it so happens that we have less charity for those who believe half our creed, than for those who deny the whole of it. Charles Caleb Colton
believe hallucinations scrooge
There's more of gravey than grave about you, whatever you are!" - Scrooge, referring to Marley's ghost which he believes is a hallucination from food poisoning Charles Dickens
believe remember cry
I verily believe that her not remembering and not minding in the least, made me cry again, inwardly - and that is the sharpest crying of all. Charles Dickens
believe soul done
Nothing that we do, is done in vain. I believe, with all my soul, that we shall see triumph. Charles Dickens
believe echoes sound
It is a silent, shady place, with a paved courtyard so full of echoes, that sometimes I am tempted to believe that faint responses to the noises of old times linger there yet, and that these ghosts of sound haunt my footsteps as I pace it up and down. Charles Dickens
believe adequate earth
And I am quite serious when I say that I do not believe there are, on the whole earth besides, so many intensified bores as in these United States. Charles Dickens
believe long people
It being a remarkable fact in theatrical history, but one long since established beyond dispute, that it is a hopeless endeavor to attract people to a theatre unless they can be first brought to believe that they will never get in. Charles Dickens
concept forward historical reason
The only reason we would go forward with this concept is for the historical preservation of the property. Kevin Campbell
concept cup forward great looking region
The Powergen Cup is a great new concept for us and one everyone at the region is looking forward to, Paul Turner
concept continued develop smaller towns
Where the Mike's concept started was in smaller towns and has continued to develop in smaller towns, and we have done well with that. Madison Jobe
conception crude early elements form history minds prevails
The so-called 'materialistic conception of history,' with the crude elements of genius of the early form which appeared, for instance, in the 'Communist Manifesto,' still prevails only in the minds of laymen and dilettantes. Max Weber
concept pervasive solve
A really important thing when you come up with a concept is that you solve a pervasive problem for people, and you don't try to create a new way to do something that isn't necessarily broken. Nick Woodman
concept fears means position promoted unequal
Long before gun control was touted as 'common sense' measures, the concept was promoted as a means to keep ethnic populations in an unequal position while assuaging the fears of whites. Niger Innis
concept overall reach
We want to reach an overall concept in the foreseeable future, Hans Tietmeyer
concept corporate foreign freedom government investors private profound property rescue respects social
We want more investors to come, to rescue the concept of corporate social responsibility. We will be a government that respects foreign investments, that has a profound respect for private property and freedom of expression. Ollanta Humala
concept difficult extinction
Extinction was a difficult concept for a 10-year-old. Nell Newman
existence indicate sign
I am waiting for a sign that will indicate to me what meaning I must give to my life, but right now my existence is satisfactory. Lucy Lawless
existence enjoyed
While I loved, and while I was loved, what an existence I enjoyed! Charlotte Bronte
existence
So much of existence is so boring. To have little moments of stupidity is always welcome. Kurt Braunohler
existence uses
I take pride in the creation of my wealth, in its existence and in the uses to which it has been and is being put. J. Paul Getty
existence amazement ifs
Existence itself is nothing if not an amazement. Good poems restore amazement. Jane Hirshfield
existence hits reason
This really hits hard. Our reason for existence is to find people. Tim Jones
existence guess
We've been in existence for 30 years, so I guess we're doing something right. Patricia Murray
existence family life moments okay private sector tendencies
I've had moments in my life when I've thought if I wasn't acting, if I wasn't doing what I do and I had a career in the private sector and I didn't have a family, that I do have some tendencies where I could really kind of have a monastic existence and be okay with it. Will Ferrell
existence poetry protest represents salute supremely
Poetry, being supremely useless, by its very existence represents a protest against the so-called 'real world' of busy-ness and moneymaking, so we must embrace, salute and support our poets. Tom Hodgkinson
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
forming government proceed
We want the negotiations on forming a new government to proceed quickly. Matthias Platzeck
formal terrible settings
I'd make a terrible practitioner of any religion in any formal setting. David Knopfler
form novel mediums
The novel has always been the form that incorporates other forms. For me, it has always been the ultimate medium. Chad Harbach
form disguise behinds
Lifelessness is only a disguise behind which hide unknown forms of life. Bruno Schulz
form good including lump magical neutrality tolerate toward
We can no more tolerate neutrality and benevolence toward every conceivable form of discourse, including that of magical thinking, than we can lump together executioner and victim, good and evil. Michel Onfray
form protesting
We are protesting a new form of dictatorship and authoritarianism. Abhisit Vejjajiva
form forward great looking moment
We're in great form at the moment and looking forward to every match. Alex Ferguson
form rapper whatever whereas
I'm an entertainer, so in whatever form I entertain... The thing about being a rapper is that you have more control over your form, whereas with acting you have to compromise a lot. Method Man
formed studios
I think the big studios shaped and formed the artists that they put under contract. Nicolas Roeg
human-nature abstinence appetite
Subdue your appetites, my dears, and you've conquered human nature . Charles Dickens
human-nature lifeless permanent
The more a thing tends to be permanent, the more it tends to be lifeless. Alan Watts
humanity architect grey
Yes, Garnett Grey was an Architect. Were a psychoanalyst to approach him from behind, tap his shoulder, and say 'Humanity,' Garrett'd spin and respond, without hesitation, 'Solvable'. Chip Kidd
humanity
We cannot trample upon the humanity of others without devaluing our own. Chinua Achebe
humanity mud practicals
We cannot trample upon the humanity of others without devaluing our own. The Igbo, always practical, put it concretely in their proverb Onye ji onye n'ani ji onwe ya: 'He who will hold another down in the mud must stay in the mud to keep him down.' Chinua Achebe
humanity end-of-the-world world
Anticipating the end of the world is humanity's oldest passtime David Mitchell
humanity originality specks
Your turn has come to sift through the dreck of humanity for rare specks of originality David Mitchell
humanity states organized
The better organized the state, the duller its humanity. David Mitchell
humanity identity divorced
Our identity was bestowed upon us by God and when humanity rebelled against God, we were divorced from the source of our identity. In this vacuum, work can wrongfully become the source of our identity wreaking havoc on our lives and work. Work was never meant to carry the weight of our identity. David Kim
lower
Most organisations do not actively seek out input from their lower echelons. Noreena Hertz
lower months move
We're going to move lower from here. It's not going to take months and months to get all these refineries back. Mark Waggoner
lower man sleeping somewhere ticket
What's lower than writing a man a ticket for sleeping on the street? If he had somewhere else to go, don't you think he'd be there? Gary Jones
lower safe sure work
We're doing everything we can to make sure it's safe to live and work in Lower Manhattan. Michael Brown
lower
If you are going to lower me into the grave, and I feel something is wrong, I will get up. Lee Kuan Yew
lower might
We might get to the lower 8,000's before we get through with this. Vince Farrell
lower trying ways
We're always trying to find ways to lower interceptions and stuff. My nature, I'm aggressive. I'll take shots, I'll take chances; therefore, you have mistakes, Brett Favre
lowering marginal middle pressure rates tax welcome
Lowering the marginal salaries tax rates is welcome and will go some way in relieving the pressure on the middle class. Paul Chan
lower
I want to lower taxes for the middle class. Donald Trump
minds product stick
We want our product to stick in the minds of consumers. Michael Sands
minds offices work
When you work at 'The Daily Show,' you have to give 100 percent, or you're gone. The competitiveness and the minds that work in those offices are incredible. Nate Corddry
mindset stay
Let's just say that at 74 I'm in the mindset that, having been free-to-air, I want to stay free-to-air. Richie Benaud
minds
should be able to make up their own minds about what they view. Chris Evans
minds
Minds that have nothing to conferFind little to perceive. William Wordsworth
mindset project trying
To get into another person's mindset and what they are trying to do with their project is a challenge, and it is what I like. David Zayas
mindset performed
We want to keep that mindset going. They've performed admirably so far. Scott Olson
minds none running
None of this has anything to do with me running. So, what's the real issue? What is the issue? I can't get into the minds of people. Ron Oden
mindset
I don't go out there with the mindset that he did this, now I'm going to better him. This game's too hard. Curt Schilling
races taking
She's taking a little break. It's just too many races for her right now, at the end of the season. Vedran Pavlek
races top trained
She's at the top of her game. She has trained excellent, and she does well when her races are spaced. Jeff Bonde
races
She's going to have one of the most competitive races in the state, Joseph Bruno
races seven six three top win
We are going to win six or seven races and be in the top three in the Chase. If we don't win the championship, it won't be by much. Dale Jr
races winning
We want to be winning races and so just being on the podium is disappointing. Jenson Button
races run trucks
I don't think you can do it with 10 races to go in trucks because we only run 25 races, Bobby Hamilton
races
I thought the races would be a little closer, Keith Williams
races
This will be one of the most competitive races in America. Morgan Dobbs
races six strong win
To win six races is something I'll look back on and think that was a strong season. Dan Wheldon
rejects-you decision accepting
God will never reject you. Whether you accept Him is your decision. Charles Stanley
rejection condemnation ifs
If you get condemnation out of the Gospel, you put the condemnation into it yourselves! It is not the Gospel, but your rejection of it that will condemn you. Charles Spurgeon
rejection ego identity
The hallucination of separateness prevents one from seeing that to cherish the ego is to cherish misery. We do not realize that our so-called love and concern for the individual is simply the other face of our own fear of death or rejection. In his exaggerated valuation of separate identity, the personal ego is sawing off the branch on which he is sitting, and then getting more and more anxious about the coming crash! Alan Watts
reject senate strongly unwise urge
We strongly urge the Senate to reject this unwise amendment, Carlos Gutierrez
rejection
Everyone fears rejection. Derek Jeter
rejects-you survivor music-business
I'm a survivor in a business that constantly rejects you. Dick Clark
rejection environment worst
As a writer, the worst thing you can do is work in an environment of fear of rejection. Carol Leifer
rejection next remember
The next time you feel rejection's sting, remember God's words to Samuel: "It is not you they have rejected, but they have rejected me." (1 Sam. 8:7) Beth Moore
rejected
I work constantly to be better at being rejected. Aya Cash