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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
anxiety lord ifs
If you have an anxiety lay it down before The Lord Charles Stanley
anxiety growth sorrow
Growth can be painful, change can be painful but nothing is as painful as staying stuck somewhere you don't belong Anxiety does not empty tomorrow of its sorrow it only empties today of it strengths Charles Spurgeon
anxiety brain attention
Conscious attention is a designed function of the brain which scans the environment for any trouble making changes. If you identify yourself with your trouble shooter, then naturally you define yourself as being in a perpetual state of anxiety. Alan Watts
anxiety nuisance uptight
Practically everybody knows what its like to feel anxious, worried, nervous, afraid, uptight, or panicky. Often, anxiety is just a nuisance, but sometimes it can cripple you and prevent you from doing what you really want with your life. But I have some great news for you: You can change the way you feel. David D. Burns
anxiety pay anticipation
The price we pay for anticipation of the future is anxiety about it Carl Sagan
anxiety insecurity may
Everyone wants to be Cary Grant. Even I want to be Cary Grant. Let me expand a bit. I sense that you may feel that I am free of problems. Let me assure you that I have the same anxieties and insecurities as anyone in this auditorium - maybe more. Cary Grant
anxiety cosmos analysis
Science is a method of logical analysis of nature's operations. It has lessened human anxiety about the cosmos by demonstrating the materiality of nature's forces, and their frequent predictability. Camille Paglia
anxiety coming good looking national next people shape waiting
We're in good shape for now, but there's still going to be this anxiety, where people are looking over their shoulders, waiting to see what's coming next on the national level. Donald Selkin
anxiety darkness doubt
Knowledge does away with darkness, [anxiety], and doubt; for these cannot exist where knowledge is. Dieter F. Uchtdorf
benefits tasks easy
It is an easy and vulgar thing to please the mob, and not a very arduous task to astonish them; but essentially to benefit and to improve them is a work fraught with difficulty, and teeming with danger. Charles Caleb Colton
benefits might alternatives
American consumers might benefit if lenders provided greater mortgage product alternatives to the traditional fixed-rate mortgage. Alan Greenspan
benefits cash size
We can guarantee cash benefits as far out and at whatever size you like, but we cannot guarantee their purchasing power. Alan Greenspan
benefits drive efforts focused offer pleased product recognized relevant source technology tremendous value
We are pleased that yet another independent source has recognized the tremendous value of our tires. Goodyear's product development efforts have focused on an application of relevant technology - advancements that are technologically innovative, but which also offer discernable benefits to those who drive on our tires. Bob Toth
benefits action longing
We must not stint Our necessary actions in the fear To cope malicious censurers, which ever, As rav'nous fishes, do a vessel follow That is new-trimmed, but benefit no further Than vainly longing. William Shakespeare
benefits brings great people rich wealth
Wealth brings great benefits to the world. Rich people are heros. P. J. O'Rourke
benefits persons
Unless what you say benefits the other person, don't say it. Denis Waitley
benefits people sick
We have no benefits at all -- no sick leave. What most people have, we don't have it. Darrell Braden
benefits card earning elite gives maximize members nights point potential rewards towards
We want our members to be able to maximize their point earning potential. This card not only allows members to earn more Marriott Rewards points, and it also gives them many benefits such as a free-night certificate yearly, and 15 nights towards Elite status. Ed French
created creates federal government job people project work
The federal government has never created one job that is sustainable long term. It creates government project work but not creating real work where people are. Michael Steele
created general government inspector position
The position of the (Interior Ministry) general inspector was not created by the government, it had been there before the new government was formed. Ghazi Hamad
created defense floor greatest man played press switch
We started out on a full-court press, but we had to switch to a man all over the floor when the press was not working. We created a lot of turnovers and our defense made opportunities for our offense. That is the greatest defense we have played all year. Jerome Antone
created genre gretzky mario wayne
Wayne Gretzky and Mario Lemieux created a whole new genre of players. Pierre McGuire
created dominated open today view wealth
Wealth today has been created by a world view dominated by fast-moving networks, open information, bottom-up entrepreneurialism. Jacqueline Novogratz
created hurt player playing style totally touch wake
We were totally playing their style most of the game. Then their player got hurt and we started playing our style which is 1-2 touch pass. We didn't wake up but once we did, we created chances. Aaron McFarland
created saying
What we're saying is that the documentation has been created to the same standard. Tom Brookes
created creating easily few finish game handle last minutes played
What a disappointing way to finish the match, especially after creating so many opportunities that we should have put away. It should have easily been 2-1 at halftime. We played to win, we created enough opportunities to win, and we didn't handle the last few minutes of the game very well at all. Steve Sampson
created invested worked
I have invested in companies. I have worked in companies. We have built companies; we have created jobs. Kenneth Langone
dealing might serving stop
We want the pedophiles to give it a thought, that they might be dealing with the police, ... And if we can stop them ... then we are serving our purpose. Robert Randall
deal dime increase nickel offer recognizes table three wage
We want them to get an offer to the table that they can live with. We want a deal that is more than just a nickel and a dime an hour. We want a deal that recognizes that they went without a wage increase for three years. Dave Minshall
deal might ready supposed systems understand whatever
We want them to be ready for whatever they might have to deal with on that first flight; to understand what to do if some of the systems don't do what they're supposed to. Jim Smith
dealing hierarchy might military properly
We want to set this up properly because we are dealing with a military hierarchy and I might set it up wrongly. Michael Defensor
deal opportunity positives sanctions ten tournament understanding
The positives are closure. We're going into the Big Ten tournament and we want our student-athletes to have the opportunity to participate in this tournament understanding there won't be any sanctions they have to deal with. ... They can play without that stress. Gene Smith
deal egyptian palate pleasures strangle whom
The pleasures of the palate deal with us like the Egyptian thieves, who strangle those whom they embrace. Lucius Annaeus Seneca
deal earn employees exemplary great hard hard-work honor proud represents salute share team work
We are proud to earn this award. It represents a great deal of hard work for us, for our suppliers and for their suppliers. We salute our team of exemplary employees and suppliers, and share this honor with them. Steve Perkins
deal later super
We started the deal and here they are 30-years later in the Super Bowl. Rolly Woolsey
deals people valuable
There are some deals to be made right now. Some people don't want to rebuild. And they don't want the headaches. But it's not as valuable as it will be in the future. Craig Brown
economics taxes
Whatever you tax you get less of. Alan Greenspan
economic plant profile
While it is true that we must seek value added industries like food processing plants and call center operations, we must do what is necessary to expand and develop our economic profile. Alan Autry
economic strengthen
We want to strengthen the commercial, economic relationship, Adnan Badran
economic currents flawed
The current economic system is fundamentally flawed and inevitably destructive. David Suzuki
economic verge
We are probably on the verge of an economic recovery. Stephen Leeb
economic luxury stage
We are at the stage of economic development where we do not have the luxury to be wasteful, Zeng Peiyan
economic market moment remarkably time virtually
We are at a moment here in economic time that things are really going remarkably well on virtually all fronts and that's why you see the market at all-time highs. Mary Farrell
economic figures last looks markets moving narrow oil percent push reason three waiting
We're in a narrow range, moving around about 1 percent over the last three days, and it looks like the markets are waiting for some economic figures or waiting on oil because there's really no reason to push anything now. David Briggs
economic-inequality long lasts
I will always have enough money to last the rest of my life...as long as I don't buy anything. Ed Asner
freedoms period protect relinquish seems short
To protect our freedoms, it seems like we're going to relinquish some of our freedoms for a short period of time. Neil Young
freedoms obama press violation
The violation of press freedoms has been egregious under this administration, even as the press fetes President Obama as an honest and effective commander-in-chief. Ben Shapiro
freedoms
As a physician, I would never encroach upon the religious freedoms of my patients. Ami Bera
freedoms national press speech
It is without doubt that freedoms of the press and speech need to be protected, but there are undisputed limits to these freedoms, limits that often come into play when national security is threatened. Charles B. Rangel
freedoms last maybe president seen sure taken wins year
Maybe after the president wins elections, as we're sure he will, the freedoms that we've seen for the Brotherhood over the last year will be taken away. Mohammed Habib
freedoms generous james mere
...Natural freedoms are but just:There's something generous in mere lust. (A Ramble in St James Park) John Wilmot
freedoms generous james mere
...Natural freedoms are but just: There's something generous in mere lust. (A Ramble in St James Park) John Wilmot
freedoms generous mere natural
Natural freedoms are but just:There's something generous in mere lust. John Wilmot
freedoms regularly understanding
Many Americans don't have an understanding of the freedoms they regularly enjoy. Dave Anderson
greatness men mind
Great men, like comets, are eccentric in their courses, and formed to do extensive good by modes unintelligible to vulgar minds. Charles Caleb Colton
greatness deserving-it mind
Great minds had rather deserve contemporaneous applause without obtaining it, than obtain without deserving it. If it follow them it is well, but they will not deviate to follow it. Charles Caleb Colton
greatness men
In life we shall find many men that are great, and some that are good, but very few men that are both great and good. Charles Caleb Colton
greatness men too-much
Speaking generally, no man appears great to his contemporaries, for the same reason that no man is great to his servants--both know too much of him. Charles Caleb Colton
great-expectations secret tears
The secret was such an old one now, had so grown into me and become a part of myself, that I could not tear it away. Charles Dickens
great-expectations strange melancholy
So new to him," she muttered, "so old to me; so strange to him, so familiar to me; so melancholy to both of us!... Charles Dickens
great-expectations may done
But, in this separation I associate you only with the good and I will faithfully hold you to that always, for you have done far more good than harm, let me feel now what sharp distress I may. Charles Dickens
great-expectations may let-me
Let me feel now what sharp distress I may. Charles Dickens
greatness excellence littles
True greatness consists in being great in little things. Charles Simmons
huge portions seeing systems
We started seeing huge vulnerabilities. And portions of those systems were extraordinarily secure. But they were Maginot Lines. Scott Borg
huge three win
We still need to win three games. I feel like if we win those three games, there's going to be a huge celebration. Luis Rivera
huge opens player space
When you take a player off the ice, even if it is your own team, that opens space and can be a huge advantage, especially when you have a player like Allie. She is just so dynamic... one of those worth-the-price-of-admission kind of players. Bill Halbrehder
huge job realized written
I was a huge rereader, so I've read all the Chronicles of Narnia, at minimum, 13 times each. In reading that series, I realized that someone had written those books, and that was that person's job. And I thought, 'That is the job for me. That is the job I'm going to have when I grow up.' Lisa Papademetriou
hugely land sale weighs whether
Whether or not a land is for sale weighs in hugely for criteria. Paul Campbell
huge next weeks
We're so young in so many areas. These next two weeks will be huge for our development. Pete Carroll
huge
There's a huge latent market for software development that's just flat-out honest. Kent Beck
huge limited
With the limited monies we've got, we know it's going to show the need for a huge appropriation by the state. Harvey Jewett
huge musical people
I'm not a huge musical fan. It's like when people just jump out singing; it's not real. Keke Palmer
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
wrong-person persons
Fear is just faith in the wrong person. Bill Johnson
wrong-person persons better-off
You are so much better off on your own than with the wrong person. Cat Deeley
wrong
We were as wrong as you could get. Gregg Laskoski
wrong-time right-thing
There is no wrong time to do the right thing. Charles M. Blow
wrong-road
You got to go down a lot of wrong roads to find the right one. Bob Parsons
wrong
With Nixon, you see the right way to do it and the wrong way to do it. Douglas Brinkley
wrong-number phones numbers
He looked from the phone to the unconscious figure of the Salesman. "What did you do to him?" he asked. "He got the wrong number," Alex said. Anthony Horowitz
wrong-things
When we hope, we usually hope for the wrong thing. Dean Koontz
wrong-things
Take Courage! Whatever you decide to do, it will probably be the wrong thing. Ashleigh Brilliant