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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
believe book writing
No men deserve the title of infidels so little as those to whom it has been usually applied; let any of those who renounce Christianity, write fairly down in a book all the absurdities that they believe instead of it, and they will find that it requires more faith to reject Christianity than to embrace it. Charles Caleb Colton
believe self denial
Forgiveness, that noblest of all self-denial, is a virtue which he alone who can practise in himself can willingly believe in another. Charles Caleb Colton
believe half literature
In religion as in politics it so happens that we have less charity for those who believe half our creed, than for those who deny the whole of it. Charles Caleb Colton
believe hallucinations scrooge
There's more of gravey than grave about you, whatever you are!" - Scrooge, referring to Marley's ghost which he believes is a hallucination from food poisoning Charles Dickens
believe remember cry
I verily believe that her not remembering and not minding in the least, made me cry again, inwardly - and that is the sharpest crying of all. Charles Dickens
believe soul done
Nothing that we do, is done in vain. I believe, with all my soul, that we shall see triumph. Charles Dickens
believe echoes sound
It is a silent, shady place, with a paved courtyard so full of echoes, that sometimes I am tempted to believe that faint responses to the noises of old times linger there yet, and that these ghosts of sound haunt my footsteps as I pace it up and down. Charles Dickens
believe adequate earth
And I am quite serious when I say that I do not believe there are, on the whole earth besides, so many intensified bores as in these United States. Charles Dickens
believe long people
It being a remarkable fact in theatrical history, but one long since established beyond dispute, that it is a hopeless endeavor to attract people to a theatre unless they can be first brought to believe that they will never get in. Charles Dickens
black calling world
If the universe is meaningless, so is the statement that it is so. If this world is a vicious trap, so is its accuser, and the pot is calling the kettle black. Alan Watts
black-and-white periods recreation
Period recreation is very difficult unless you make a black-and-white movie. Alan Parker
black magic mind
Magic is a state of mind. It is often portrayed as very black and gothic, and that is because certain practitioners played that up for a sense of power and prestige. That is a disservice. Magic is very colorful. Of this, I am sure. Alan Moore
black done facts
The writer cannot expect to be excused from the task of reeducation and regeneration that must be done. In fact, he should march right in front. Chinua Achebe
black ships peter
That is the Wasp, yes. But it was captured by Black Stache, and he’s coming for this ship now.” “And how do you know that?” asked Slank. “Did a seagull tell you?” This brought chuckles from the crew. Something like that, thought Peter. Dave Barry
black laughed ifs
If Black Stache laughed, you laughed. If he snarled, you snarled. If he breathed in your direction, you ran for cover. Dave Barry
black-and-white computer fascinated
It was a black and white only computer at the time, but it kept me fascinated. Buffy Sainte-Marie
black taught moments
At this moment, then, the Negroes must begin to do the very thing which they have been taught that they cannot do. Carter G. Woodson
black movement yards
I had formed a black movement, so I would speak for the Trotskyist movement and then walk about a hundred yards to where the black movement was speaking. C. L. R. James
fairy airy idealist
Don't make me into this airy-fairy, moralist, idealist because I'm not. Madeleine Albright
fairy born humans
You mocking changeling- fairy-born and human-bred! Charlotte Bronte
fairy-stories facts looks
Only thin, weak thinkers despise fairy stories. Each one has a true, strange fact hidden in it, you know, which you can find if you look. Diana Wynne Jones
fairytale focusing result send
We're focusing enough on doing what we have to do to get the right result and send him off with the fairytale end. George Gregan
fairy people tales
Many people think fairy tales and retellings of fairy tales are only for children, but I'm not the only writer to take an old tale and retell it for a sophisticated adult audience. Kate Forsyth
fairy hope influenced shows work
All of my work is influenced by fairy tales, and I hope my work shows Hans Christian Anderson's influence. Sandra Cisneros
fairy-tale invention tales
Fairy tales only happen in movies." -George Melies from The Invention of Hugo Cabret Brian Selznick
fairy charm true-gifts
Charm is the true gift of the Fairies. Charles Perrault
fairy love sort tale
I love that very traditional fairy tale where it's not all 'happily ever after.' I like all that old school, bloody, 'Brothers Grimm' sort of stuff. So you have all those shades of gray in there. Erin Morgenstern
finding-peace peace-on-earth teach
The person who finds peace inside and lives it, is the one who teaches what true peace is. Byron Katie
finding ourselves
We started off slow, but we're finding ourselves in each and every game. Nathan Taylor
finding-the-one littles interest
You will soon find that I am a bit obsessive about my work. And that is a little sad, one often feels strangely restricted, not finding time to simmer, although one actually has many interests. Arne Jacobsen
finding-yourself fame illness
There's probably no experience more alienating than fame, other than a terminal illness, where you actually find yourself in a situation that nobody around you can relate to. Diablo Cody
finding-someone share something-you-love
Success is finding something you love to do, getting paid to do it and finding someone to share it with. Dick Clark
findings
Got to start by finding it, have we? Can't start by looking for it, I suppose? C. S. Lewis
finding obsession truth
When you're working for yourself and your own obsession with finding the truth, you're at your own mercy. Errol Morris
finding guru joining work
I don't like the idea of spirituality done the way it's done. The only way I could understand it was through creativity, not by going to an Ashram, or finding a guru or joining a temple. I made work out of it. M.I.A.
finding presumably proposal realistic takes today
What they presumably need to do today is come up with something that is realistic enough and acknowledges enough of the judge's finding that he takes the proposal seriously. Kevin Arquit
hopeless situation finality
You'll never convince me there is a hopeless situation or there is any finality in any success or any failure. Carlos Ghosn
hopeless-romantic might looks
I might look like a tough chick - and I am - but I`m also a hopeless romantic inside. Avril Lavigne
hopeless friendless alas
Alas, I am a woman friendless, hopeless! William Shakespeare
hopelessly
I find the aesthetics of the 20th century hopelessly barren. Twyla Tharp
hopeless
Hope is the most hopeless thing of all. Abraham Cowley
hopeless-romantic sticks hopeless
I'm a hopeless romantic, I say very loudly and proudly. I get a lot of stick for it. Alex Pettyfer
hopeless should situation
That the situation appears hopeless should not prevent us from doing our best. Aldo Leopold
hopeless-romantic hopeless
I'M A HOPELESS ROMANTIC Aaron Paul
hopeless
Nothing is as bad as a marriage that's a hopeless failure. D. H. Lawrence
likely rockets solid violent whether
Whether solid rockets are more or less likely to fail than liquid-fuel rockets is debatable. More serious, though, is that when they do fail, it's usually violent and spectacular. Henry Spencer
likely puts september window
We're going to have to make some modifications to the tank, so that probably puts the September (launch) window into a not very likely possibility. William Gerstenmaier
likely understanding
We're more likely to be understanding than to be judgmental. David Carr
likely meaning ourselves setting tie
When our purpose is external, we may never find it. If we tie our purpose or meaning to our vocation, goal or an activity, we're more than likely setting ourselves up for suffering down the line. Kris Carr
likely volume
I'm working on something that's not yet novel-shaped but is something of a film-noir-flavored 'Alice in Wonderland.' It will also very likely be a single volume story and not the start of a series. Erin Morgenstern
likely normally problem
Least likely normally to have a problem is the kicker. Dick Vermeil
likely multiple parties
Settlement talks, if any, will likely be very complex, with multiple parties involved. Henry Blodget
likely problem
The overcrowding problem is likely to get worse. Keitaro Matsuda
likely overall remain sales somewhat total
The overall total of nominal sales is likely to remain somewhat weak. Anthony Chan
love lost-youth ideas
I don't remember who was there, except Dora. I have not the least idea what we had for dinner, besides Dora. My impression is, that I dined off Dora, entirely, and sent away half-a-dozen plates untouched. I sat next to her. I talked to her. She had the most delightful little voice, the gayest little laugh, the pleasantest and most fascinating little ways, that ever led a lost youth into hopeless slavery. She was rather diminutive altogether. So much the more precious, I thought. Charles Dickens
love mind unhappy
There can be no disparity in marriage like unsuitability of mind and purpose. Charles Dickens
love friendship relationship
Never close your lips to those whom you have already opened your heart. Charles Dickens
love powerful disappointment
Mystery and disappointment are not absolutely indispensable to the growth of love, but they are, very often, its powerful auxiliaries. Charles Dickens
love honesty heart
To conceal anything from those to whom I am attached, is not in my nature. I can never close my lips where I have opened my heart. Charles Dickens
love mean men
You know what I am going to say. I love you. What other men may mean when they use that expression, I cannot tell. What I mean is that I am under the influence of some tremendous attraction which I have resisted in vain, and which overmasters me. You could draw me to fire, you could draw me to water, you could draw me to the gallows, you could draw me to any death, you could draw me to anything I have most avoided, you could draw me to any exposure and disgrace. This and the confusion of my thoughts, so that I am fit for nothing, is what I mean by your being the ruin of me. Charles Dickens
love lying men
What lawsuits grow out of the graves of rich men, every day; sowing perjury, hatred, and lies among near kindred, where there should be nothing but love! Charles Dickens
love night reality
I loved you madly; in the distasteful work of the day, in the wakeful misery of the night, girded by sordid realities, or wandering through Paradises and Hells of visions into which I rushed, carrying your image in my arms, I loved you madly. Charles Dickens
love christmas education
I will honor Christmas in my heart, and try to keep it all the year. Charles Dickens
news good-news
The good news isn't that God is victorious. How can He not be victorious? The good news is we can be victorious, too. Aiden Wilson Tozer
news chaos should
Chaos should be regarded as extremely good news! Chogyam Trungpa
news foxes doe
Critics of Fox News have pointed out that Fox News does partisan propaganda, and there's ample evidence on a daily basis. David Shuster
news watches my-sister
My sister's the type who religiously watches the fear segments of her local Eyewitness News broadcasts, retaining nothing but the headline...Everything is dangerous all of the time, and if it's not yet been pulled off the shelves, then it's certainly under investigation -- so there. David Sedaris
news-stories years marketing
Other than that one year, Salon has been very cautious about the way it spends money. For instance, since last year, we've had virtually no marketing budget. It's just word of mouth. And our circulation continues to grow that way by breaking news stories. David Talbot
news youth
It's lamented that the youth get their news from Jon Stewart and Stephen Colbert. It's lamentable that they get more from them than from the news. Dick Cavett
news
Who, or why, or which, or what, Is the Akhond of Swat? Edward Lear
newspapers said evidence
The newspapers at one time said that I was dead but after carefully examining the evidence I came to the conclusion that this statement was false. Bertrand Russell
news agendas ranting-and-raving
The failures of the press have contributed immensely to the emergence of a talk-show nation, in which public discourse is reduced to ranting and raving and posturing. We now have a mainstream press whose news agenda is increasingly influenced by this netherworld. Carl Bernstein
tells
If you want to communicate with the American public, the literature tells you you've got to be talking at about a sixth-grade, seventh-grade level. Richard Carmona
tells
We usually end up crying. He tells us not to be scared. Melinda Shiraki
tells
No one ever tells us the truth, even those we love. Anna Held
tells
No one tells salesmen what they can and can't do. Barbara Corcoran
tells
Every forward is selfish, and any forward who tells you he is not selfish is a liar. Luis Suarez
tells
Nobody tells you Rwanda looks like Tuscany with its tiled roofs. Joanna Lumley
tells whatever wife
Whatever my wife tells me to do with it, Judd Gregg
tells
He tells guys, 'Go out there and play hard, but have fun,' Kenny Lofton
tells
He may. I think he does some things that tells you he can be in that running. Frank Beamer
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
true-love heart men
My heart is set, as firmly as ever heart of man was set on woman. I have no thought, no view, no hope, in life beyond her; and if you oppose me in this great stake, you take my peace and happiness in your hands, and cast them to the wind. Charles Dickens
true-friend ambition character
A high character might be produced, I suppose, by continued prosperity, but it has very seldom been the case. Adversity, however it may appear to be our foe, is our true friend; and, after a little acquaintance with it, we receive it as a precious thing - the prophecy of a coming joy. It should be no ambition of ours to traverse a path without a thorn or stone. Charles Spurgeon
true-friend sharks blood
There are no true friends in politics. We are all sharks circling, and waiting, for traces of blood to appear in the water. Alan Clark
true-knowledge sustenance
True knowledge without xperience is food without sustenance David Mitchell
true-friend thinking knows
The WORK 1.Is it true? 2.Can you absolutely know that it's true? 3.How do you react when you think that thought? 4.Who would you be without the thought? Byron Katie
true-friend love-you opposites
You know who your true friends are when things go wrong for you, but the opposite is also true. When things go well, the people who really love you are happy. Carlos Ruiz Zafon
true-identity people acting
I've scammed so many people throughout my whole life who never learned my true identity until I started acting. Charlie Bewley
true-love home causes
Well I never had a place that I could call my very own/That's all right, my love, 'cause you're my home. Billy Joel
true-friend select
True friends are families which you can select. Audrey Hepburn