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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics.
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online.
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services.
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts.
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters.
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here,
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof.
approved consumers contain dangers diet difficult experience fda origin people physicians pills problems products purchase side trace treat unknown
There are dangers to consumers who purchase diet pills that contain drugs of unknown origin and quality. These products are not approved by the FDA and if people experience side effects, it is difficult to trace problems and for physicians to treat them.
approved aware hold positions similar
We were aware that they were approved for positions that, I believe, are very similar to the positions they hold at Christina.
approved enclosed phase similar
We were approved for 18 new units in January. The new units will be similar to the ones in phase II, in that they will be in an enclosed space. Jim Davies
approved district fields four money spending
We're spending the money the district approved four years ago. I have not enough fields and too many teams, Andy Dick
approved develop glad information people school team
We're going to have information on how people can develop a team and we will tell them what their responsibilities are. It's just getting started right now. I'm glad that the school has approved it.
approved board directors specific unless until
unless and until its board of directors has approved a specific transaction.
approved bankruptcy fully united
United fully complied with the solicitation and tabulation procedures, which were approved by the bankruptcy court.
approved board commission planning somewhat unusual
Usually if a Planning Commission is on board and their recommendations are incorporated into the plan, it's somewhat unusual to not have it approved by the council.
approved demand hungarian ministers names president submitted
Upon this the Hungarian ministers resigned, but the names submitted by the president of the council, at the demand of the king, were not approved of for successors. Lajos Kossuth
attempts crack fraudulent license possible step
We want to take every possible step to crack down on fraudulent attempts to get a driver's license in New Mexico.
attempted break hit seem sell stores sure week
The other stores don't seem to be hit like they are -- there was an attempted break just a week ago, ... I'm not sure if what they sell is more attractive.
attempt develop efforts land opposed persistent
The persistent efforts to develop the accreted land are unconscionable, ... Any such attempt will be vigorously opposed by the association and its members.
attempting dress jeans possibly realized remember run silicon tech trying valley
The perception in Silicon Valley is that if you dress well, you couldn't possibly be smart, or you're in P.R. but couldn't possibly run a company. I remember briefly attempting the Adidas and jeans and sweatshirt over T-shirt look, but I realized I was trying to dress like a young tech geek, and that just wasn't me. Leila Janah
attempts cost desire disconnect faster jack point prices push rapidly starts
The point comes where there starts to be a disconnect between the attempts to rapidly jack up those prices for faster MIPS and IBM's desire to push the cost of MIPS down,
attempt congress office structure
unprecedented attempt by Congress to structure the office of the president. John Roberts
attempts banning believe ether gasoline known laws proposed provisions regarding state
We believe that provisions in the proposed legislation regarding reformulated gasoline are back-door attempts at invalidating state laws banning the use of methyl tertiary butyl ether (MTBE), a known carcinogen.
attempted believe cast emotional focusing kim lawyers main rather severe terrible toward
We believe that Mr. Baldwin has severe emotional problems. Mr. Baldwin's lawyers attempted to cast terrible aspersions toward Kim rather than focusing on the main issue, which is his daughter.
attempting offer program
We are attempting to offer the program statewide.
bothering-you bother ifs
If something is bothering you, keep it to yourself. David Strickland
both discovery driven east finds fossil mary since understand
With the discovery of Zinjanthropus at Olduvai Gorge in 1959, my grandmother Mary Leakey pioneered the research in East Africa with my grandfather Louis. Many more spectacular fossil finds have since been made, both in Africa and elsewhere, by many researchers driven to understand our past. Louise Leakey
both since
Wendy and I both wanted kids, but since we were pushing 40, the clock was ticking. Lisa Cholodenko
both feed suffice
I care not to debate which came first, Islamism or anti-Muslim bigotry; suffice to say that both feed into each other symbiotically. Maajid Nawaz
both direct guess project serious
There is a healthy fraternal rivalry, but nothing serious and we both have been looking for a project to do together. I guess he may direct me in a project some day. Mackenzie Astin
both country english federal issue kinds language laws learn official people practical side state
The other side said (there are) 799 federal and state laws mandating the use of English. ... We would say those kinds of laws are not at issue here. I think that English is the official language of this country in a practical sense already. And I think that most people who come here both learn English and want to learn English.
both checks dressing great knows reason rooms sit sound together worse
The other reason Rufus and I are great together is that we're both really lazy. The rehearsing, the sound checks -- he's actually worse than I am, and that's something. To get us to do anything other than sit in our dressing rooms is a challenge. Who knows what will happen? Ben Folds
both potential
The potential is unbelievable with both those girls.
both huge potential sales
The potential is huge for them both in sales and production.
constitution should caution
The Constitution is a document that should only be amended with great caution. Carl Levin
constitution court decided essential fee imposing indiana pleased programs school services
We are pleased the court decided the Indiana Constitution prohibits the Evansville school corporation from imposing a fee for programs and services that are essential to young Hoosiers' education.
constitution subvert truth united wants
The truth is that anyone... that wants to subvert our Constitution to Shariah Law is an enemy of the United States. Louie Gohmert
constitution not-sure consent
I consent Sir, to this Constitution because I expect no better, and because I am not sure, that it is not the best. Benjamin Franklin
constitution
We seek not to overthrow the constitution, but to overthrow those who would prevert it. Abraham Lincoln
constitution deliberate division emphatic extensive majority power preventing unbridled
In the Constitution of the American Republic there was a deliberate and very extensive and emphatic division of governmental power for the very purpose of preventing unbridled majority rule. Robert W. Welch, Jr.
constitution government great republic
Our constitution works. Our great republic is a government of laws, not of men. Gerald R. Ford
constitution
Our constitution got built around the idea of minority protection. Eula Biss
constitution continue county department engaged ensure equitable fair ferguson louis places work
Ferguson and St. Louis County are not the first places that we have become engaged to ensure fair and equitable policing, and they will not be the last. The Department of Justice will continue to work tirelessly to ensure that the Constitution has meaning for all communities. Eric Holder
contentment alive able
For unless one is able to live fully in the present, the future is a hoax. There is no point whatever in making plans for a future which you will never be able to enjoy. When your plans mature, you will still be living for some other future beyond. You will never, never be able to sit back with full contentment and say, "Now, I've arrived!" Your entire education has deprived you of this capacity because it was preparing you for the future, instead of showing you how to be alive now. Alan Watts
contentment unhappy not-happy
I'm not "happy" but I'm not unhappy about it. Alan Bennett
content continuous cycle deep focused incredibly information internet newspaper opinion post provides responds smart voices work
The Post newspaper provides an incredibly deep and smart opinion report. The Web-only content supplements that with some different voices and with work that responds to the Internet's continuous news cycle and is more focused on Internet information sources.
content delivered digital excited gamers incredibly providing xbox
We're incredibly excited about providing gamers with that they want - inexpensive and entertaining digital content delivered right to their Xbox 360,
content depth elements enterprise greater guiding inclined information key multiple news principle quickly readers serve stories tailor true web work
We're increasingly inclined to put our scoops on the Web before publication in the newspaper. Our guiding principle should be to serve our readers first, getting news and information out as quickly as possible. It's also true that some stories just work better in print, particularly enterprise and investigative work with multiple elements and greater depth and length. The key is to tailor the content to the platform. Ken Paulson
contention happy mind three
We have to find three more tenths tomorrow. We have something in mind. We're just happy to be in contention for a medal.
contentment wish littles
My motto is: Contented with little, yet wishing for more. Charles Lamb
contentment digital needs
Digital piracy needs to be addressed. Without content protection, investment in content can't be supported. We need secure distribution. If you (telecommunications equipment and software makers) help us, we will make it easier for you to distribute our content. Bob Iger
content eat family good home older sit string
I have a good family and I like to be home with them. The older I get, the lazier I get, and the more content I am to sit at home and eat string cheese. Michael Ian Black
dangerous
Life has to be dangerous. Alain Robert
danger dangers perceived potential problems quite realistic
The possibility of danger is there, but the realistic dangers are quite remote. People's perceived potential problems are something they have to conquer.
dangerous dreading
We've already had some dangerous situations, and I am really dreading March.
dangerous dread grass january month number situation
We've already had a dangerous situation in January with a number of grass fires. But the month I dread is March.
danger focus helping immediate period point prevention
We are at this point not in any immediate danger. We are in a period in which we need to focus on prevention and helping each other as much as possible,
dangerous extremely hackers issue microsoft sets sharing smart takes time tools using
There are some extremely smart hackers out there using and sharing the tools that find these vulnerabilities. When Microsoft takes a long time to issue fixes, it sets up a dangerous situation,
dangers four impress likely odds parents schools severe students teach three trying week
We're in schools at least three or four times a week trying to teach students and parents about the dangers on the Internet. We try to impress upon them that the odds are in their favor. They most likely won't be a victim, but if they are, there can be severe consequences.
dangerous extra half pass played second spread tonight
We spread them out and made the extra pass in the second half. The first half was one pass and one shot. You got to at least make them play defense, we didn't do that in the first half. We could have been pretty dangerous tonight if we played all 32 minutes.
danger evidence found rather
I don't think anyone's found a way of eliminating thoughts of danger and loss. It's rather that, when they're unrealistic, you become an acrobat at marshaling evidence against them. Martin Seligman
deepening despite efforts life oriented remain tendency time toward wholly
The tendency of our time is wholly oriented toward the secular. The efforts of the mystics will remain episodes. Despite a deepening of our conceptions of life, we will build no cathedrals. Ludwig Mies van der Rohe
deepening delaware entire examine facts join project region supporting trust
Mr. Speaker, the Delaware River deepening project is important for my constituents, for our region and for the entire nation. I trust that, when they examine the facts about it, every one of my colleagues will join me in supporting it.
deepening extending poetry publishing range
Elaine Equi has been publishing her observant, often playful poetry for some 30 years, extending and deepening the range of her intrinsically wry voice.
deepening ears eyes far government rural
The government is deepening its crackdown in Ethiopia's rural areas, far from the eyes and ears of international observers.
deepening democracy knowledge
Participants take part in a combination of caucuses, presentations and activities, all aimed at deepening their knowledge of American democracy and the free-enterprise system.
deepening quick
That was kind of my first impression: Wow, this one is deepening as quick as Andrew, ... It's larger.
deepening foreign framework peace region relations stability tehran ties
Deepening ties between Tehran and Kabul in the framework of peace, development and stability in the region is one of the Kabul foreign relations priorities. Abdullah Abdullah
deepening heads
deepening the divides, in people's heads and sometimes in their hearts.
deepening violence
deepening its involvement in incitement, violence and terror. Ariel Sharon
dividends foul great importance paid stress
We stress foul shooting. It is something we place great importance on every day. It paid dividends tonight.
dividends faster growing period seeing
What's interesting now is we're seeing a period where dividends are growing faster then earnings,
divided problems solve united
United we can solve our problems and divided we have nothing. Louis Farrakhan
divide individual information investors traders
With the Internet, the information divide between professional traders and individual investors has become very small.
divide kinds people
There are two kinds of people in this world - those who divide everything into two and those who don't Robert Benchley
dividends fortunate paying strengthen teach techniques therapy
I was fortunate to have a grandfather who was an optometrist. Vision therapy was something that we routinely did to strengthen our eyes and give us better focus. I was fortunate that he could teach me techniques that are still paying dividends for me to this day. Larry Fitzgerald
divided favorable seniors
Seniors are still divided as to being favorable or unfavorable, but many still don't know enough to have an opinion.
dividends engagement policy shown
The policy of constructive engagement has shown some dividends but not as much as we had hoped. Najib Razak
divide divine invariably perceive talked unable
I have often talked with angels on this subject, and they have invariably declared that in heaven they are unable to divide the Divine into three, because they know and perceive that the Divine is One and this One is in the Lord. Emanuel Swedenborg
divisions facto number shrinking taking
What they're really doing is taking their divisions and shrinking their number in a de facto way.
divisions group operating outdoor pleased record results stations television
We're pleased to see improvements in all segments, ... The company's stations group had record operating results with each of the divisions - radio, outdoor and television - contributing to the results. Mel Karmazin
divisions historian nixon reagan richard structure subject
My big subject as a historian is how Americans divide themselves. What are the divisions that structure our political lives. Richard Nixon and Ronald Reagan were perfect foils for that story. Rick Perlstein
divisions fighters four good puerto rican title
To be the first Puerto Rican to win a world title in four divisions would be an achievement. Gomez, Benitez, there have been a lot of good fighters from Puerto Rico before me. When I started boxing, Tito Trinidad was our big star. Miguel Cotto
divisions eat hardcore
You can be vegetarian and eat fish. It's your choice, just say: 'I am what I am.' There are no hardcore divisions anymore. Yotam Ottolenghi
divisions elsewhere few second stars third thousands
Obviously, you'll still need a few stars elsewhere in the world, but not the hundreds and thousands who play in the second or third divisions in other countries. Sepp Blatter
divisions huge
I don't think we'll see huge divisions here in Greece.
divisions hard lower playing stepping
It has been hard for some of them, stepping up from the lower divisions where they are playing a lot more games, is tough. John Toshack
divisions great three
We will have three different divisions playing. We should have great participation and it should be as competitive as it has always been. Robert Williams
ethnicity interesting long
As long as our civilisation keeps trundling along generally forwards, then there is the possibility of a future where ethnicity is merely an interesting badge, not a uniform you can't take off. David Mitchell
ethnicity people age
After Zorro, people spoke Spanish to me for ages. I'm Welsh but that movie instantly gave me a new ethnicity. Catherine Zeta-Jones
ethnicity world sometimes
Sometimes my ethnicity is relevant, other times not. I definitely get the best of both worlds. Archie Panjabi
ethnicity years agents
I have always let the lack of Indian actors in the industry drive me, not hold me back. I remember an agent in L.A. telling me a few years ago that an Indian actor wouldn't ever make it in Hollywood, but my ethnicity has helped me.
ethnicity people great-work
Regardless of your ethnicity or anything, if you do great work, people will notice and you'll get hired. Aziz Ansari
ethnic groups patrol putting quite together
(The patrol force) is pretty extensive, ... You are putting ethnic groups together ... It is quite a mix.
ethnicity race world
The Klan sees the world in terms of race and ethnicity. So do Liberals Ann Coulter
ethnic groups happens middle people religious rooms share smack worst
Some of the worst violence in the world today between estranged religious and ethnic groups happens not on the battlefields. It happens smack in the middle of living rooms and between people who share a lot, who have a lot in common. Miroslav Volf
ethnic good
I don't think it's a good thing to have Christian states, Muslim states, or any kind of ethnic states. Norman Finkelstein
likely rockets solid violent whether
Whether solid rockets are more or less likely to fail than liquid-fuel rockets is debatable. More serious, though, is that when they do fail, it's usually violent and spectacular. Henry Spencer
likely puts september window
We're going to have to make some modifications to the tank, so that probably puts the September (launch) window into a not very likely possibility.
likely understanding
We're more likely to be understanding than to be judgmental. David Carr
likely meaning ourselves setting tie
When our purpose is external, we may never find it. If we tie our purpose or meaning to our vocation, goal or an activity, we're more than likely setting ourselves up for suffering down the line. Kris Carr
likely volume
I'm working on something that's not yet novel-shaped but is something of a film-noir-flavored 'Alice in Wonderland.' It will also very likely be a single volume story and not the start of a series. Erin Morgenstern
likely normally problem
Least likely normally to have a problem is the kicker. Dick Vermeil
likely multiple parties
Settlement talks, if any, will likely be very complex, with multiple parties involved. Henry Blodget
likely problem
The overcrowding problem is likely to get worse.
likely overall remain sales somewhat total
The overall total of nominal sales is likely to remain somewhat weak.
maintain point travel
We still maintain that travel is not to be interrupted in the world at this point of time.
main
I always feel calmer when I exercise. In fact, that's probably the main reason I exercise. Gretchen Rubin
maintaining-the-status-quo innovation needs
Philanthropy is involved with basic innovations that transform society, not simply maintaining the status quo or filling basic social needs that were formerly the province of the public sector. David Rockefeller
maintain ways
Ways have to be found to maintain university research untramelled by requirements of forecasting application or usefulness.
main theater whenever
Whenever we are not doing a show in our main theater or after the main show, we will do things down here.
maintain played playing score trying
We were trying to maintain where we were at (down by 10), but when you can't score it makes it really hard. Chesterton started playing better on offense, and we played worse.
main
'Cloud Atlas' is for everybody. The main character in the movie is humanity. Andy Wachowski
mainly providing shower
We're mainly providing a place to sleep, shower and use restrooms. Robert G. Allen
maintain rather stadium
We would rather not maintain the new stadium if we didn't have to.
overcome thinking
You do have to overcome the child's thinking that this new woman, who is not their mother, is going to be in their lives. Nancy O'Dell
overcome
Nothing is difficult, if one can overcome with it !
overcome
He was able to overcome everything. He's an inspiration to me and to others. Adam Brown
overcome
I think we will be able to overcome these issues, Charles Clark
overcome problems work
If we work together, we can overcome these problems, Manmohan Singh
overcome pain
If we can keep him pain-free for a long time, he can overcome it.
overcome punch red trying
We're young right now and we're trying to overcome some of that. We just weren't able to punch it in down in the red zone.
overcome
Yeah, they're good. It will be another challenge. But if we play well, we can overcome it. Michael Cole
overcome played
We should have played better, especially in the first half, but we were able to overcome our difficulties.
process tainted
The possibility for the process to be tainted is just too much.
process seeing spreading
We are seeing a process of spreading poverty.
process
Interleaf is based on the formatting process. Bill Joy
process force establishing-relationships
Mothering/nurturing is a vital force and process establishing relationships throughout the universe. Bernice Johnson Reagon
process riot learning-process
The learning process is something you can incite, literally incite, like a riot. Audre Lorde
process animation dislike
I don't dislike the process of animation... I find it daunting, but only as much as I find everything daunting. Bill Nighy
process
We have no idea how long this process will take. Bruce Miller
process honestly whole
Honestly, I was offended by the whole process, Chandler Parsons
process performing
Performing, for me, has always been a very inner process. Barbra Streisand
rather sooner
We're insisting that it be sooner rather than later.
rather
Like Hubie, and sometimes like Jim, I can be rather lengthy. Jim Calhoun
rather rule
made it a rule ... rather than the exception.
rather record
I'm a lazy guy. I can't focus for too long. I'd rather hear a record that has no filler. Thomas Mars
rather work
I don't know about hiding away, but I really only like to present myself when I'm working on something - it's more my work I like to present to the world rather than myself. Kate Bush
rather
I am not into action and adventure on holiday; that doesn't really do it for me. I would much rather go and lie down. Keeley Hawes
rather stated
Mohamed stated he would rather kill only Americans.
rather strange
So I think it is rather strange that I got into ballet, something that I hadn't seen. Suzanne Farrell
rather survive taken
She was rather abrasive and difficult, but it must've taken that kind of personality to survive and to do what she did in the 1960s.
sides god-is-with-us
God works, and therefore we work; God is with- us, and therefore we are with God, and stand on His side. Charles Spurgeon
sides actors safe
An actor always goes to the safe side. Chloe Grace Moretz
sides darker-side
Vocally, I really like going into the darker side of myself. Dave Gahan
side wants
The other side wants to make me the issue, Jack Thompson
sides aspect
There are a lot of similar aspects in all the religions. The question is which side of it you hold up. Madeleine Albright
sides homosexual borderline
I have this side of me that is a very European flamboyant; I won't say queenie, but it's borderline - could be perceived as homosexual. Charlie Bewley
sides spirit good-health
I would like to explore some side roads in life while I am still in good health and good spirits. Charles Kuralt
sidelines standing coaches
I suppose I'm like most coaches now, standing on the sideline hoping somebody asks them a question. Bobby Bowden
sides action side-effects
No action is without its side effects. Barry Commoner
steps backing-up steady
History has spurts and then is steady, and then maybe even backing up a step, and then forward again. Alan Bean
step
We want to take a step forward. There's some worries. But you just go in there and play.
steps surprise reader
I really like it when you can step outside of what's come before and find a surprise for the reader and find a surprise for yourself. Dave Gibbons
steps tough push-yourself
You take yourself to a place where you've got absolutely nothing left and then you find out you have to push yourself one more step. That's a tough place to be in. Bryan Clay
steps comfort grows
It is only when You really STEP OUT of Your comfort zone that You GROW. Bear Grylls
steps problem illegal
Illegal immigrants are already a very big problem for us. We are already taking big steps to disallow illegal immigrants from coming in. Antonis Samaras
steps commencement experiments
One failed experiment is one step closer to Success Denzel Washington
steps should
Until we see what we are, we cannot take steps to become what we should be. Charlotte Perkins Gilman
steps looks hard
It's hard to see things when you're too close. Take a step back and look. Bob Ross
three four finished
In 1980 I finished three or four times in seventh place. Alain Prost
three balls easy
The three-ball is an easy shot if you're uncontested, but when they know you can shoot, it's a lot harder to get off. Chris Copeland
three essentials action
There are three essential factors in all human activity: spirit, materials, and action. Chiang Kai-shek
three kind i-can
I can find only three kinds of business in the Universe: mine, yours, and God's. Byron Katie
three england beats
When you beat Arsenal, they are a good three points. Bryan Robson
three
The other three have really made strides. They're consistently getting better.
three
We've already got three up on the board. Steve Alford
three moments hours
Preferred three hours quicker over one moment late. William Shakespeare
three kind persons
Before repeating something bad about another person, ask yourself these three questions: Is it true? Is it necessary for me to tell it? Is it kind to tell it?
within
I would say it's more within my expectations.
within
We're number-crunching to see what we can do within our mandate. Michael Mann
within work
We will have to work within the budget.
within work
We work within the system. I don't want to say we're rebellious.
within
We have very well-trained RAs and RDs within residence halls,
within
Typically within two weeks, we're done with the analysis.
within work
We have to learn how to work within the limits that are possible, not what is desirable.
within
We should be able to energize it within one or two days.
within
They say, 'we're within the treaty, we're within our rights'.