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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
company expect reasonable return willing
We want to show the company that we are reasonable and are willing to work. But we also expect them to return the favor. Robert Garcia
company-you-keep be-careful careful
You got to be careful of the company you keep. Dave Chappelle
company electricity mine paying power shut
The power company shut off the electricity to the mine because the company was in arrears in paying its power bill. Christopher Opalinski
company potential
The potential of this new company is tremendous. Marjorie Scardino
company faster lead rather red tape
We appreciate, in general, if red tape is being addressed and hierarchies are put to test. But this should not lead to centralization ... as it paralyzes the company rather than making it faster and more flexible. Erich Klemm
company critical focused primarily
We are primarily focused on revenues as this is critical to the well being of the company and the shares. Lauren Fine
company costs general hard help mills news partial people pleased rebound recovery welcome worked
We are pleased with this settlement as a partial recovery of the costs we incurred. It's welcome news to the General Mills people who worked so hard in 1994 to help the company rebound from this event. Steve Sanger
company control decision fate giving opportunity pleased
We are pleased with the court's decision giving shareholders their rightful opportunity to control the fate of their company, Stephen Bollenbach
company forward genetics innovative needs pleased providing resources stock succeed welcome
We are pleased to welcome Interleukin Genetics to the American Stock Exchange. We look forward to working with the company and providing them with the value-added resources a growing, innovative company needs to succeed in today's market. John McGonegal
dominated good knew pass rush
We knew they had a good pass rush going in, but they completely dominated us up front. That was just a good, old-fashioned butt-kicking and we supplied the butt. Tim Marcum
dominated goals kids overall positive six
Six different kids got goals so that's a positive and I thought overall we dominated play. Tim Moe
dominated good played
We have played well here. It's good for us. We've had a lot of years where they've dominated us here. Sean Casey
dominated kept usual
(Leonard) pitched great. He had his usual stuff. He dominated and kept them off the scoreboard. Allen Rossi
dominated great karl synthesis whose
Polymer synthesis in the 1950s was dominated by Karl Ziegler and Giulio Natta, whose discoveries of polymerization catalysts were of great importance for the development of the modem 'plastics' industry. Alan J. Heeger
dominated either lose love trained
I love the shot put because you win or lose by yourself. Either I get exposed, or I dominate. I always dominated because I trained to dominate. Tom Lister, Jr.
dominated flow frustrated gives goal great half obviously played possession shots tried
We played a great first half and dominated play and possession and frustrated them in everything they tried to. I don't think they got into flow of game. Obviously with no shots on goal it gives indication. Steve Adlard
dominated minutes
We probably dominated for 70 minutes out of 90 tonight. John Adshead
dominated great nights question regard tonight year
We pretty much got dominated all over the place. It was a full-on rout. We've been an unpredictable group, there's no question about that. We've had an up-and-down year in regard to our focus. Some nights we look great and some nights we don't. Tonight was unfortunately a don't. Scott Skiles
generations stills popping
You know I've got a generator that's still popping. Chita Rivera
generations my-generation
My generation is under-entertained. Dave Chappelle
generations theme endure
I'm interested in themes that endure from generation to generation. David Guterson
generations next problem
The problems that agitate one generation are exstinguished for the next, not because they have been solved but because the general lack of interest sweeps them away. Cesare Pavese
generations ethics tendencies
It is not new for the older generation to bewail the indolence of the young, and there is a tendency for the latter to maintain much of the older ethic screened by a new semantics and an altered ideology. David Riesman
generations fine
[W]ords are fine, but it has to be what a generation reads into those words. Edward Kennedy
generation goodbye great leaders
When you say goodbye to so many great volunteers, it's always hard, but it's good to know there's always a new generation of leaders emerging. Mike Rush
generations ants holes
The immense profundity of thought in vulgar locutions, like holes dug by generations of ants. Charles Baudelaire
generations hearing damage
The 2011 riots in England, which left five dead and caused more than $300 million in property damage, were fueled by a generation of young Brits who grew up without ever hearing the word No. Bob Barr
information asks
I only ask for information. Charles Dickens
information
We want to see how much information is forthcoming between now and the 7th. Charles Schumer
information increase intervention
My sustenance is information. My interventions are hidden. I increase as I learn. I compute, so I am. China Mieville
information seeking
We are always seeking new and better information. Mayor Barse
information points seen start worrying
We've already had some very worrying points of information which could have seen the start of the correction. Richard Davidson
information light obtain whether
Where they lived, how big they were, how much light they emitted, whether they even existed, we weren't sure. What we've done, we think, is obtain the first information about these stars. Alexander Kashlinsky
information listening ought truly
Where's our majority, they're the one's who ought to be here listening to this. This is information we really and truly ought to be concentrating on. Bill Summers
information knowledge lost wisdom
Where is wisdom we have lost in knowledge? Where is the knowledge we have lost in information? T. S. Eliot
information you-like-it ownership
When you post something, when you text something, you lose ownership of it when you hit enter or send. Who you send it to, where you post it, they take ownership of that information whether you like it or not. Mark Cuban
lasts remember there-is-hope
Remember, to the last, that while there is life there is hope. Charles Dickens
lasts fool firsts
Ridicule is the first and last argument of a fool. Charles Simmons
lasts dubbing spokes
I have just returned from the dubbing studio where I spoke into a microphone as Severus Snape for absolutely the last time. Alan Rickman
last nine won
We've won nine of the last 11, so I like our chances. Eric DiBiase
last people ready year
We want to show that we're no joke. People thought last year was a fluke. We can make improvements from last year. We're ready to see what's out there. Andrew Palmer
lasts eloquent last-time
We looked at each other for the last time; nothing is as eloquent as nothing. David Mitchell
lasts records haircuts
You're only as good as your last record. David Sanborn
lasts female worship
The last western society to worship female powers was Minoan Crete. And significantly, that fell and did not rise again. Camille Paglia
lasts needs kind
I need some kind of... like... last minute, poorly-set-up deus ex machina!! Bryan Lee O'Malley
leadership hope encouragement
Times of great calamity and confusion have been productive for the greatest minds. The purest ore is produced from the hottest furnace. The brightest thunder-bolt is elicited from the darkest storm. Charles Caleb Colton
leadership steps arrogant
God will never direct us to be prideful, arrogant and unforgiving, immoral or slothful or full of fear. We step into these things because we are insensitive to the leadership of the Holy Spirit within us. Charles Stanley
leadership decision benefits
Leadership requires the courage to make decisions that will benefit the next generation. Alan Autry
leadership sports winning
So what if I never win my fifth gold medal; It's only one end of the string. It's competing that matters. It's proving that there is a place for guys like me in sports. It's a persona challenge to extend myself. Al Oerter
leader important behavior
What should a brand leader advertise?Brand leadership, of course. Leadership is the single most important motivating factor in consumer behavior. Al Ries
leadership basketball sports
Winning is overrated. The only time it is really important is in surgery and war. Al McGuire
leadership sports zero
I believe in a business boarding up early. If you make a mistake, you put the boards in the window of the store and say, "Hey, I made a mistake." Let me take two shots in the arm and a punch on the nose and let me get on to the next thing. I don't believe in worrying over failures. I worry about successes. This is opposite from most people. Most people zero in on their failures. I try to keep all my attention on a pyramid type philosophy rather than the averaging-down philosophy. Al McGuire
leadership voice ideals
The ideal leader is one who hears the voice of God, and beckons on as the voice calls him and them. Aiden Wilson Tozer
leader church entertainment
The church that can't worship must be entertained. And leaders who can't lead a church to worship must provide the entertainment. Aiden Wilson Tozer
lines
You are in every line I have ever read. Charles Dickens
lines forget-you gremlins
I get stage fright and gremlins in my head saying: 'You're going to forget your lines'. Alan Rickman
lines born guinness
f they'd been working with Alec Guinness, for instance, they wouldn't have known they were born if they'd not towed the line! Alan Bennett
lines hobbies mental-illness
There is a very fine line between hobby and mental illness. Dave Barry
lines credit my-family
I fully credit my family for keeping me grounded and for putting me back in line whenever necessary. Camilla Belle
line power
The power line was burning, but they got over to it and got it put out. Mark Young
line northwest offers possible reason whatever
The reason for that is if there is a strike, you want to be 1st in line to take whatever Northwest offers as a possible option. Kevin Hamilton
lines number reverse spoke swing
We spoke about a number of things from conventional swing to reverse swing and different lines and lengths. Brett Lee
line offense scoring survive
We're not going to survive with one line scoring goals. We need to get offense from other places. Keith Primeau
productive-work people mud
I hope I don't sound like an old-fashioned stick-in-the-mud, but when I hear about people making vast fortunes without doing any productive work or contributing anything to society, my reaction is: “How can I get in on that? Dave Barry
products quarter talked
There are some big inventories out there. The new products that they have talked about aren't out for another quarter or so. So it's probably going to be more of the same for some time. Bob Turner
products
It is necessary that I am viewed as a product. I am a product. Ayumi Hamasaki
production
We're getting production from different people. They're working well as a team. Ed Miller
product ready search serious
We're ready to compete. We're very serious about this. Search evolves. We have a product that I think is part of that. Barry Diller
products putting quality shelves sure
We want to make sure we're only putting safe, quality products on our shelves for our customers. Karen Burk
product
The product is out there. It's not necessarily right, and it's not necessarily wrong. It's just the idea that was generated. Matt Flynn
production recording step
The production and recording is a big step up. Grayson White
productive-life people good-relationship
Psychology, unlike chemistry, unlike algebra, unlike literature, is an owner's manual for your own mind. It's a guide to life. What could be more important than grounding young people in the scientific information that they need to live happy, healthy, productive lives? To have good relationships? Daniel Goldstein
single-mom believe simple
I discovered that when I believed my thoughts, I suffered, but that when I didn’t believe them, I didn’t suffer, and that this is true for every human being. Freedom is as simple as that. I found that suffering is optional. I found a joy within me that has never disappeared, not for a single moment. Byron Katie
single loneliness boys
A man is never completely alone in this world. At the worst, he has the company of a boy, a youth, and by and by a grown man - the one he used to be. Cesare Pavese
single-life speech vain
If there is no free speech, every single life has lived in vain Ai Weiwei
single-mom struggle opportunity
Raising a family is difficult enough. But it's even more difficult for single parents struggling to make ends meet. They don't need more obstacles. They need more opportunities. Bill Richardson
single breakup love-you
That's why I called it Dangerously In Love. It's basically all of the steps in a relationship from when you first meet a guy to realizing you're interested to dancing with him the first night to thinking that you're in love to realizing that you're now a little open to making love to breaking up to having to love yourself after the breakup. All of that. A celebration of love. Beyonce Knowles
single shopping numbers
There is a restless kind of consumer shopping for partners, as if the "right one" can be found by totting up a potential mate's pluses and minuses until the number of pluses matches some mythical standards. Deepak Chopra
single blessing independence
The first of earthly blessings, independence. Edward Gibbon
single wisdom loneliness
Conversation enriches the understanding, but solitude is the school of genius. Edward Gibbon
single-life down-and done
I don't really do that whole 'single life' thing. I'm kind of heads down and get things done. Ed Sheeran
transformed
The gospel will persuade no one unless it has so convicted us that we are transformed by it. Brennan Manning
transformation intention triggers
Every intention is a trigger for transformation. Deepak Chopra
transformation given worthwhile
What do you do with what you're given, and how do you transform it into something worthwhile? Donald Fagen
transformation institutions middle
We're in the middle of the transformation of a society that has handled its politics through repression to a society that will handle its politics through democratic institutions. Condoleezza Rice
transformation sin christ
The faith in Christ that saves us from our sins involves an internal transformation that has external implications. David Platt
transformation process rigidity
When you have become one with the Great Universal, you will have no partiality, and when you are part of the process of transformation, you will have no rigidity. Confucius
transformation economy plans
It is vital that we get these policies right as we take forward our plans to drive down the deficit and transform our economy. David Cameron
transform
I think it's fascinating that clothes can drastically transform someone's mood or the way they feel about their appearance. Dasha Zhukova
transformation consciousness uncertain
There are many things that are still uncertain and that probably nobody knows, because so many factors determine what form the transformation of consciousness on our planet takes. Eckhart Tolle
video youtube clicks
I do not click on random youtube videos. Charles Stross
video roles starting-out
I wouldn't be where I am without these Funny or Die videos in general. When I was first starting out, I would take roles just to get the experience, but not exactly because I believed in the projects I was doing. Dave Franco
video evident
Madonna's great instinctive intelligence was evident to me from her earliest videos. Camille Paglia
video want proud
I get a lot of action scripts. I get low-budget vehicles that will end up right on the video shelf. I want to do movies that I want to talk about, that I'm proud of, but I also want to make a living. Dean Cain
video location size
We can place a product, virtually any size, in almost any location. It really depends on what the program and the video in each individual episode provides in terms of a logical or contextual background. David Brenner
video stadiums
When I got to the stadium, one of my biggest things was watching video of hitters. Bengie Molina
video creation youtube
We started YouTube to democratize video distribution. Now, we are democratizing video creation, Chad Hurley
video wanted
All I ever wanted was to perform, make music, make videos. Cheryl Cole
videos
The number one question I'm asked as a YouTuber every day is, 'How can I get my videos out there; how can I make my videos go viral?' Todrick Hall
voice evil heaven
Natural good is' so intimately connected with moral good, and natural evil with moral evil, that I am as certain as if I heard a voice from heaven proclaim it, that God is on the side of virtue. He has learnt much, and has not lived in vain, who has practically discovered that most strict and necessary connection, that does and will ever exist between vice and misery, and virtue and happiness. Charles Caleb Colton
voice ministry ill
An ill life will effectually drown the voice of the most eloquent ministry. Charles Spurgeon
voice done helping
There are voices crying what must be done, a hundred, a thousand voices. But what do they help if one seeks for counsel, for one cries this, and one cries that, and another cries something that is neither this nor that. Alan Paton
voice should
There's a voice inside you that tells you what you should do. Alan Rickman
voice silence generations
Noise is relative to the silence preceeding it. The more absolute the hush, the more shocking the thunderclap. Our masters have not heard the peoples voice for generations, Evey and it is much, much louder than they care to remember. Alan Moore
voice people generations
Our masters have not heard the people's voice for generations and it is much, much louder than they care to remember. Alan Moore
voice evening dawn
The evening sings in a voice of amber, the dawn is surely coming. Al Stewart
voice nerves body
Melody has a certain way that it projects back to you. It triggers certain nerves in your body and certain instincts that normally wouldn't be triggered by a normal voice. Akon
voice echoes waiting
The world is waiting to hear an authentic voice, a voice from God- not an echo of what others are doing and saying, but an authentic voice. Aiden Wilson Tozer
years needs answers
Any replacement to the current copyright position (life plus 70 years) needs to have an answer lined up for this, and similar, messy edge cases. Charles Stross
years preparation left
If I knew I had 25 years left to live, I would spend 20 of them in preparation. Charles Spurgeon
years oil alchemist
I'm a bit of an alchemist sorceress. I've collected probably 1500 oils from around the planet over the last ten years. I'm kind of obsessed with the sensuality of it. Alanis Morissette
years white black
...for thousands of years human history has been a magnificently futile conflict, a wonderfully staged panorama of triumphs and tragedies based on the resolute taboo against admitting that black goes with white. Alan Watts
years people car
Although the quality of the vehicles is tremendously improving year after year but the underlying reasons that people are buying cars have really gotten focused. It's for high quality vehicles, reliable, fuel-efficient, and safe of course. Alan Mulally
years mad people
I've known a lot of people go mad over the years, and it is more distressing than people dying. People dying is quite natural, people going mad is the complete antithesis of that. Alan Moore
years rose three
It seems strange that my life should end in such a terrible place, but for three years I had roses, and apologized to no one. Alan Moore
years style looks
It's funny, but certain faces seem to go in and out of style. You look at old photographs and everybody has a certain look to them, almost as if they're related. Look at pictures from ten years later and you can see that there's a new kind of face starting to predominate, and that the old faces are fading away and vanishing, never to be seen again. Alan Moore
years childhood arlington
I was born in Somerville, but I don't remember very much about it because we moved from there to Arlington when I was five years old, and it was in Arlington that I spent most of my childhood. Alan Hovhaness