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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
business soul prosperity
Industry is the soul of business and the keystone of prosperity. Charles Dickens
business fighting men
An Irish man fights before he reasons, a Scotchman reasons before he fights, an Englishman is not particular as to the order of precedence, but will do either to accommodate his customers. Charles Caleb Colton
business men morality
Most men are individuals no longer so far as their business, its activities, or its moralities are concerned. They are not units but fractions. Charles Dickens
business clever men
The first rule of business is: Do other men for they would do you Charles Dickens
business law brain
Contract law is essentially a defensive scorched-earth battleground where the constant question is, "if my business partner was possessed by a brain-eating monster from beyond spacetime tomorrow, what is the worst thing they could do to me?" Charles Stross
business past derivatives
It seems superfluous to constrain trading in some of the newer derivatives and other innovative financial contracts of the past decade. The worst have failed; investors no longer fund them and are not likely to in the future. Alan Greenspan
business colleagues depends
...our market system depends critically on trust-trust in the word of our colleagues and trust in the word of those with whom we do business. Alan Greenspan
business years risk
What we have found over the years in the marketplace is that derivatives have been an extraordinarily useful vehicle to transfer risk from those who shouldn't be taking it to those who are willing to and are capable of doing so. Alan Greenspan
business greatness views
I have found no greater satisfaction than achieving success through honest dealing and strict adherence to the view that, for you to gain, those you deal with should gain as well. Alan Greenspan
corporate
[The business is] more corporate and more formulaic and less experiential. Alan Arkin
corporate
I won't be making any friends in the corporate suites. Carl Hiaasen
corporate report
We want to see a prosecution of corporate manslaughter. This report has re-opened that possibility. Louise Christian
corporate economy market profits recover sooner stock telling
What the stock market is telling you is that the economy and corporate profits are going to recover sooner than thought. Vince Farrell
corporate economic fight fights gate next reaction seen smaller
We want his next fight to be in Little Rock, but it would have to make economic sense to us. I need to get a sense of the corporate reaction that, frankly, we haven't seen for the smaller fights in Little Rock. We need a gate that's competitive with Vegas. Lou DiBella
corporate definitive events investors last resolution seeing sentiment today wait week
What we're seeing today and what we have been seeing for the last week is a drying up of sentiment as investors wait for some definitive resolution of world events and some new corporate catalysts. Scotty George
corporate crucial earnings economy excess fact focusing forgetting good growth margin money needs negative quite relative stocks supply third
We're focusing much too much on what's moving, which at the margin are the kind of that are negative for stocks and forgetting what's really crucial here. The fact is we are in an excess supply of money relative to the needs of the economy and corporate earnings growth will in fact be quite good in the third quarter. Ron Hill
corporate growing positive prices rising stock three together
Three things out there: very, very positive liquidity, a growing economy, and rising corporate profits. Put those three things together stock prices have only one way to go and that's up. Ronald Hill
corporate knew short sponsors struggle time uphill
We knew this would be an uphill struggle to find corporate sponsors in so short a time frame. Ernest Collins
correlate hard result statistics trying
You're trying too hard to find a correlation here, ... You don't know these people, you don't know what they intended. You try to compile statistics and correlate them to a result that amounts to nothing more than speculation. Marc Racicot
correlate stock
They're doing well because they don't correlate to the stock market. Tom Grzymala
correlate success
He's energized. He's having fun. Hopefully, that can correlate to success on the field. Romeo Crennel
correlate favorite stage stuff theater time watching
I started in community theater at 7 years old. I loved being on stage and performing. At the time, I didn't correlate that the stuff I was doing on stage was the same thing that I was watching in my favorite films. Jessica Lucas
correlate lack legal ratings
Impairment ratings don't necessarily correlate with functionality or lack thereof. Impairment ratings are legal numbers. Dr. Johnson
engineers needs scientists ultimately
Ultimately Halcyon needs the greatest scientists and engineers in the world to succeed in its mission. Luke Nosek
engineers improve microsoft plan presented professor proposed work
The only plan professor Barrett has presented was in January, when he proposed that he work with Microsoft engineers to improve the documentation. Jonathan Todd
engineers founders
Many of those founders were not only engineers but immigrants. Carl Guardino
engineers level none scale
None of us have enough engineers to do what we need to do. You get scale on the engineering level by doing alliances and you get scale on the costs. Jim Olson
engineers equipment mention pakistan send soon sort winter
He did not mention it. It's more use for us to send engineers with road-clearing and snow-moving equipment - because it will be winter soon - than that sort of operation, which, to my knowledge, Pakistan has not requested. Hoop Scheffer
engineers humbled naturally perfect respect science stuff system technology treated
Because they are so humbled by their creations, engineers are naturally conservative in their expectations of technology. They know that the perfect system is the stuff of science fiction, not of engineering fact, and so everything must be treated with respect. Henry Petroski
engineers favorite moving nobody organized people phenomenon start walking
The phenomenon was that people who were walking at random, at their own favorite speed, not organized in any way, spontaneously synchronized, ... That's the phenomenon. Why did they all start moving in step? They did it unconsciously. That is what nobody had thought about and engineers did not anticipate. Steven Strogatz
engineers fifteen huge seems
Fifteen seconds, seems huge to me. We have engineers who say, if you could give me 100 nanoseconds, it would be useful. Lucy Jones
engineers fifteen huge seems
Fifteen seconds, seems huge to me, ... We have engineers who say, if you could give me 100 nanoseconds, it would be useful. Lucy Jones
focus ego attention
The ego is nothing other than the focus of conscious attention. Alan Watts
focus listening theatre
Acting is mostly about listening. If you just focus in on what the other person is saying, acting takes care of itself to quite a large extent. Alan Rickman
focus-and-concentration long calm
As long as I can concentrate and remain somewhat calm, I can normally do very well. Al Oerter
focus good-things happens
Good things happen when you narrow your focus Al Ries
focus albums guests
Any album that you pick up of mine, you know it's an Akon album. The guests are very limited, and you get to really feel the experience. You get the Akon experience when you get the albums. I always want to make sure that stays the way it is. I don't want to flood the album to where you lose focus on why you bought it. Akon
focus violence murder
The message [of Donald Trump] is that that type of thing happening. Let's focus on what happened.What happened was the murder, the murder of this person pushing a stroller, it's unacceptable in an American city to continue to have this level of violence and the level of violence in Chicago is unacceptable. Chris Christie
focus helping strategy
The expensive ones are for Starz. No. We decided, as part of our Encore strategy, to broaden and strengthen and help focus the Encore plexus by adding original programming. Chris Albrecht
focus mind calm
Whenever your mind is totally absorbed in whatever activities you are performing, your mind will remain calm and content. Chin-Ning Chu
focus effort luck
To gain paying customers you'll need to focus on attracting the right followers, and not just on attracting the most. Communicate often with useful information to increase your value, and focus on pitching your product in a genuine way. Make sure you have a professional web presence, and with any luck, you should start noticing your efforts pay off. David Rusenko
fresh miss perfume
The perfume is sweet, like the girl, and is young and a fresh reinvention of Miss Dior. John Galliano
fresh-start finals breaths
You can make a fresh start with your final breath. Bertolt Brecht
freshman good leadership potential quite role seems since stepped taken time waiting year
When (Foster) was a freshman she had a good year and we've been waiting since that time for her to play up to her potential and this seems to be the year. She's taken on a leadership role with our team. It wasn't quite expected, but she's stepped into the role. Terri Cash
freshman nobody stand
When he got a rebound, nobody was going to take it away from him. For a freshman to go in and make that kind of a stand is very significant. Jim Calhoun
fresh guys legs spread
We've always spread it around. All the guys give you a little something different. And I think fresh legs are important. Brad Childress
freshman home living period stay
When I was a freshman living in the dorms I went home a lot, but now that I live off-campus I really can't stay home for a long period of time. Desarae Garland
freshmen guys last maybe older quite ready realized stand wondering
We're going to solidify a lineup. There was a lot of things that went on last weekend. We just wanted to see what guys were made of. We realized that some of the freshmen weren't quite ready yet, and I think in the same aspect, we have some older guys that maybe started wondering where they stand with the team. Robby Wine
fresh game keeping people stay stories
We're going to play around with keeping the show fresh and creative, but the game is going to stay the same and real people who have interesting stories are going to be at the core. Mitch Metcalf
fresh kid liked movies music people seen
I really look up to Will Smith. He's internationally known, and people know him from everything. I don't know any kid who hasn't seen and liked Fresh Prince, or you'll like one of his movies or his music. He's perfect, and he's done everything. That's my dream: to be internationally known. Keke Palmer
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
leadership hope encouragement
Times of great calamity and confusion have been productive for the greatest minds. The purest ore is produced from the hottest furnace. The brightest thunder-bolt is elicited from the darkest storm. Charles Caleb Colton
leadership steps arrogant
God will never direct us to be prideful, arrogant and unforgiving, immoral or slothful or full of fear. We step into these things because we are insensitive to the leadership of the Holy Spirit within us. Charles Stanley
leadership decision benefits
Leadership requires the courage to make decisions that will benefit the next generation. Alan Autry
leadership sports winning
So what if I never win my fifth gold medal; It's only one end of the string. It's competing that matters. It's proving that there is a place for guys like me in sports. It's a persona challenge to extend myself. Al Oerter
leadership basketball sports
Winning is overrated. The only time it is really important is in surgery and war. Al McGuire
leadership sports zero
I believe in a business boarding up early. If you make a mistake, you put the boards in the window of the store and say, "Hey, I made a mistake." Let me take two shots in the arm and a punch on the nose and let me get on to the next thing. I don't believe in worrying over failures. I worry about successes. This is opposite from most people. Most people zero in on their failures. I try to keep all my attention on a pyramid type philosophy rather than the averaging-down philosophy. Al McGuire
leadership voice ideals
The ideal leader is one who hears the voice of God, and beckons on as the voice calls him and them. Aiden Wilson Tozer
leadership work reality
I would rather die than be in the United States Senate. I would be bored to death. Could you imagine me, banging around that chamber with 99 other people, asking for a motion on the amendment in the subcommittee? Forget it...You'd watch me just walk out and walk right into the Potomac River and drown. That would be it. Chris Christie
leadership health eye
The President's biggest problem right now is he's gotta tell the truth. And we've seen this in New Jersey. I've told lots of hard truths in New Jersey that people didn't necessarily agree with, but they give you credit for looking them in the eye and telling them the truth. Chris Christie
momentum financial possibility
In an economy that already has lost some momentum, one must remain alert to the possibility that greater caution and weakening asset values in financial markets could signal or precipitate an excessive softening in household and business spending. Alan Greenspan
momentum narrative mosaics
Momentum, in literary mosaic, derives not from narrative but from the subtle, progressive buildup of thematic resonances. David Shields
momentum tomorrow starting
Momentum is only as good as tomorrow's starting pitcher. Earl Weaver
momentum seen
We have seen a lot of momentum buying, Richard Herring
momentum
When we go down to Miami, we've got to keep the snowball going. We've got momentum going. We've got confidence. So we've got to keep it up. Ben Gordon
momentum
When we go down there, we've got to keep the snowball rolling. We have momentum right now. We have confidence. So we need to keep that up. Ben Gordon
momentum side
We feel the momentum is on our side now. Dave Tippett
momentum evolution human-nature
Human nature, as manifested in tribalism and nationalism, provides the momentum of the machinery of human evolution. Arthur Keith
momentum taking
Momentum switches in a heartbeat, ... I thought we were taking it to them, then there was one extraordinary play by their guy. ... I'd like to have it over again. Ken Klee
strategic
We have to be more strategic in the distribution, David Satcher
strategic wise
I think the wise and strategic thing to do is to have a two-track policy, David Smith
strategic
That was the attraction. It was a tremendously strategic location. David Strow
strategic turkey united
The long-term strategic goals of Iran and the long-term strategic goals of Turkey are close to the long-term strategic goals of the United States. Stephen Kinzer
strategic terrific
Rubbermaid and Newell are a terrific strategic fit, John McDonough
strategic
I don't really see anything new from a strategic standpoint. Matt Rosoff
strategic view visit
The visit is significant in view of the strategic partnership between the two countries. Navtej Sarna
strategy habit achieve
Achieve success in any area of life by identifying the optimum strategies and repeating them until they become habits. Charles J. Givens
strategy takes
We're going to set our strategy and do what we think it takes to win. It won't be cheap. Lauren Cercone
strategy towards
One thing that is challenging Dell is its strategy towards higher-end products, Sam Bhavnani
strategy
My strategy is just to attack, attack and attack. Don Frye
strategy
And whereas [Donald] Trump let two or three hanging curveballs go by, [Mike] Pence will not, unless they have a strategy to let them go by. Donald Trump
strategy surround talk
Our strategy with someone like this is ... surround and talk. And we will talk for a long time. Bill Toohey
strategy
Part of our strategy is to be able to effectively encircle Yugoslavia for 360 degrees. Jamie Shea
strategy force company
Every new change forces all the companies in an industry to adapt their strategies to that change. Bill Gates
strategy structured suicide
We need to put a clear, structured suicide preventions strategy in place, Patricia Grogan
strong jobs men
No two things differ more than hurry and dispatch. Hurry is the mark of a weak mind, dispatch of a strong one. A weak man in office, like a squirrel in a cage, is laboring eternally, but to no purpose, and is in constant motion without getting on a job; like a turnstile, he is in everybody's way, but stops nobody; he talks a great deal, but says very little; looks into everything but sees nothing; and has a hundred irons in the fire, but very few of them are hot, and with those few that are, he only burns his fingers. Charles Caleb Colton
strong mind haste
Hurry is the mark of a weak mind, dispatch of a strong one. Charles Caleb Colton
strong party reason
He that aspires to be the head of a party will find it more difficult to please his friends than to perplex his foes. He must often act from false reasons which are weak, because he dares not avow the true reasons which are strong. Charles Caleb Colton
strong hands monsters
The mob is a monster, with the hands of Briareus, but the head of Polyphemus,--strong to execute, but blind to perceive. Charles Caleb Colton
strong advice desire
When we feel a strong desire to thrust our advice upon others, it is usually because we suspect their weakness; but we ought rather to suspect our own. Charles Caleb Colton
strong passion may
Strong as our passions are, they may be starved into submission, and conquered without being killed. Charles Caleb Colton
strong men thinking
Men of strong minds and who think for themselves, should not be discouraged on finding occasionally that some of their best ideas have been anticipated by former writers; they will neither anathematize others nor despair themselves. They will rather go on discovering things before discovered, until they are rewarded with a land hitherto unknown, an empire indisputably their own, both right of conquest and of discovery. Charles Caleb Colton
strong circles errors
Unity of opinion is indeed a glorious and desirable thing, and its circle cannot be too strong and extended, if the centre be truth; but if the centre be error, the greater the circumference, the greater the evil. Charles Caleb Colton
strong two mind
No two things differ more than hurry and despatch. Hurry is the mark of a weak mind; despatch of a strong one. Charles Caleb Colton
totally
We were totally inept, to put it bluntly. Larry Coker
totally
At the end of the day, the numbers that we're hearing are not going to be totally correct or not correct at all. Eugene Levy
totally
We won't be totally disappointed because there will be other goodies in the package, Parris Chang
totally
The real breakthroughs will be in a totally different category. David Schultz
totally
When I'm playing as an actor, I don't want to interfere at all with the director. I'm just an actor. I'm totally respectful. Jordi Molla
totally
She was very distressed. She was very angry, she was very upset, and all of that is totally understandable. John Howard
totally
Sometimes there has to be a goat on some level, and I'm totally fine with that being me. Abby Wambach
totally whatever
We're not the same team. We're totally different. Whatever it is, we've got to keep it up. Tubby Smith
totally
Right now, I'm totally back, because I can do everything. Andray Blatche