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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
analysis logic cases
Programmers are not to be measured by their ingenuity and their logic but by the completeness of their case analysis. Alan Perlis
analysis balls needs
All that analysis is well and good, but what I need right now is a left-handed batter who can hit the ball over the shortstop's head. Casey Stengel
analysis appreciate based conducting decision diligence reaching
We appreciate the Commission?s diligence in conducting its analysis and reaching a decision based on real, farm-level conditions. Charles Kruse
analysis based believe hearing outcome quickly recall stock storm
We believe that the Firestone recall is a storm that will intensify with the upcoming congressional hearing and then quickly pass. Based on our analysis of the outcome of other high-profile, controversial recalls, the stock should make a recovery. John Casesa
analysis last phase several
We're in a phase of analysis that will last several days. Elio Rupo
analysis confirm letter navy
What the NOAA letter does is confirm that the Navy analysis is fundamentally flawed. Michael Jasny
analysis paralysis
He suffered from paralysis by analysis. Bill Vaughan
analysis apparent became began best college marketing maximize perspective sales sports
When we began our analysis of the videogame landscape, it became apparent that EA SPORTS was best positioned from a marketing and development perspective to maximize the sales opportunities for college football. Pat Battle
analysis data effect nutrients
We can do a lot more analysis on this data set to systematically investigate these nutrients and their effect on their endpoints. Barbara Howard
combined current investor parts perception positive price reaction result share sum worth
The positive share price reaction is a result of investor perception that the sum of the parts is worth more than the current combined businesses. Keith Bowman
combined cycle fire footprint high ideal incredible innovation performance platform power previous price sun
We're in a new cycle of innovation for SPARC that delivers incredible performance gains, ... Scalable high performance processing, combined with the same power consumption, footprint and price as previous generations, make the new Sun Fire servers the ideal platform for server consolidation. David Yen
combined global great market order portfolio position product strategy support validated
We also solidified the transformation of our product line, and the market validated our strategy with every order during the year. Our new portfolio of airplanes from 100 to 450 seats, combined with our global support services, put us in a great position for the long term. Alan Mulally
combined generation glad ice
We're so glad to be a part of this generation of ice dancing. It's a combined score. Tanith Belbin
combined create downward economy global pressure third
What's new about the global economy is First World productivity combined with Third World wages. That can create some real downward pressure on high-wage countries. Harley Shaiken
combined incredible learning
With their combined knowledge, it's just incredible . . . I'm learning something new every day, Duane Campbell
combined costs increased innovative overall product products provide reduce scale
With the increased scale of the combined company, we can reduce overall product costs and provide more innovative products at more competitive prices. Bill Watkins
combined count longer short trips
Make your trips count too, don't do too many short trips try to combined the trips into one longer trip. Ken Davis
combined customer moving offer range single toward wide
When you're able to offer the customer a whole wide range of communications products, it's more attractive, ... The world is moving toward bundles and combined packaging, and not single products. Ted Rogers
invaluable planning relationship
He's been invaluable in our discussions and our planning going forward, and the working relationship has been outstanding. Andrew Friedman
invaluable leadership trying
He understands everything we're trying to do. He's invaluable to us, more so for his leadership than anything else. Rich Rodriguez
invaluable middle near placed simply students
Our students won't simply be placed at the back of a section. They'll be right in the middle of the action, near the front. It will give them invaluable experience. Timothy Dean
invaluable money time
Time is a resource, much like money or autonomy, which can be invaluable or can be squandered. Chris Gabrieli
invaluable played playing time tonight
(Cronin) got invaluable playing time tonight and I thought he played very well for his debut. Steve Sampson
invaluable preparing ready until
You never feel like you're really ready for this until it happens. Preparing for a big to-do like this is an invaluable experience. Keith Reynolds
invaluable
They have been invaluable in the development of the team, in every aspect. Daniele Audetto
invaluable natural protected sure
It's really an invaluable natural resource. We wanted to make sure it's in a protected state. Patrick Cox
invaluable job learn time
It's an invaluable time for him because he can learn so much. It's a little disappointing we didn't get the job done. Ron Rivera
picks
You don’t get to pick where you’re from, but you always have control of where you’re going. Chris Colfer
pick practice
We have to get focused. This was pretty much a practice game. Now we have to pick it up and play really hard. Jessie Coiffard
pick reason
We're going to have to (wait). There's no reason to pick one right now. It's not clear-cut enough to say one's better than the other. Wes Meier
pickles
Squeamish stomachs cannot eat without pickles. Benjamin Franklin
pick time
We're battling, and that's all you can do. This time of year, you can't make any trades, you can't pick up anybody. You have your team. This is what you do. You go play. Gary Williams
pick vegas
Vegas is going to pick up, too, ... If you want to party, everything's there restaurants, gaming. Roger Dow
pick stop trying
making excuses. Why don't they let the inspectors do their job? Stop making excuses, stop trying to politicize the operation, stop trying to pick the inspectors. James Rubin
pickles information internet
Turns out, theres not a lot of information about pickles on the Internet. Brian Posehn
picked
Ah... romance to me is spontaneity. It's not diamond earrings; it's a bunch of daffodils that's freshly picked from the field. Kate Winslet
played taken
We've already done that. The two quarterbacks we have, Vincent hasn't played before and Gill played JC. We've taken out as much as we can. Hal Mumme
played stopped ways
We stopped doing all the little things that we did earlier. We reverted back to some of our old ways and played with not a lot of intensity. Mike Pomerenke
played stood
We stood up to the challenge. We played very well. We did not play well enough to win. Dave Odom
played
We started a little slow, but we hadn't played any. Scooter Dunn
played since team time
We were a whole different team since the first time we played them. Indy Uhlenhopp
played teams
'Justified' is one of the greatest teams I've ever played for. It's just awesome. Neal McDonough
played
When we weren't in the box, I thought we played pretty well. Jeff Halpern
played proud starting
We're starting to come together. We played as a team, and I was very proud of them tonight. Travis Paquet
played prepared time
We're more prepared for it than the first time we played them. Jeff Perreault
rate
But at any rate, the point is that God is what nobody admits to being, and everybody really is. Alan Watts
rates worse
This rates up there as one of the worse we have ever seen. Mark Langan
rate recognized
We have recognized that our churn rate was too high, and we have been monitoring the credit, Chase Carey
rates wants
Let's get one thing straight: No one wants Stafford loan interest rates to increase. John Kline
rates
Different industries have different risks and growth rates and volatility. Leon Black
rate turkey
Turkey does not have an official exchange rate target. Ali Babacan
rate stays taxes
The (property tax) rate stays the same, but the taxes go up all the time. John Parsons
rate success
The rate of success is high, under the appropriate circumstances. David Fischman
rated reflects strengthen tendency
There's a tendency for the yen to strengthen because it's rated highly, but I don't think that accurately reflects Japan's economic performance. Yoshihiko Noda
resources
We're getting a lot of good, technological resources we can use. David Taylor
resources
There are only so many resources that can be allocated to these programs. Jon Purnell
resources minutes
Time is your most precious resource; make every minute count. Brian Tracy
resources using
I'm using all my resources to help me with that and I feel the sky is the limit for me. William Green
resources sue
We don't have the resources to sue everybody. Norm Zada
resources planets
The planets resources are rare; we must consume more ethically and equitably. Alain Ducasse
resources supporters
There are so many more resources in Harrisburg. I have a boatload of supporters there. Pauletta Vaughn
resources supplies sure trying
We're trying to make sure that the residents that are out there have the supplies and resources that they need, and that they are safe. Brent Nelson
resources
You have more resources than you can probably imagine. Sue Densmore
smarter stupid
We know we have to sharpen up a lot. We've got to play smarter and not make stupid passes." () Chris McCray
smarter new-yorkers
Every writer at the New Yorker is smarter than me. Bob Dylan
smarter
Education doesn't make you smarter. Aleksandr Solzhenitsyn
smarter year
I'm a lot smarter than I was a year ago. Kevin Heath
smarter
He's got to be smarter with his pitches. David Daniels
smarter
I think Marvin would have been the smarter hire, but I'm biased, Brian Billick
smarter sometime technology
Humanity is smart. Sometime in the technology world we think we are smarter, but we are not smarter than you. Mitchell Baker
smarter
We're a lot smarter now than we were in 1999 and 2000. William Dugan
smarter store
You're a smarter shopper when you go into the store with $30 in your pocket. H. Hunt
successful mislead-us watches
Falsehood is never so successful as when she baits her hook with truth, and no opinions so fatally mislead us as those that are not wholly wrong, as no watches so effectively deceive the wearer as those that are sometimes right. Charles Caleb Colton
success pride winning
To know a man, observe how he wins his object, rather than how he loses it; for when we fail, our pride supports us - when we succeed, it betrays us. Charles Caleb Colton
success achievement conceit
Success seems to be that which forms the distinction between confidence and conceit. Charles Caleb Colton
success hate men
For one man who sincerely pities our misfortunes, there are a thousand who sincerely hate our success. Charles Caleb Colton
success kissing hands
To judge by the event is an error all commit: for in every instance courage, if crowned with success, is heroism; if clouded by defeat, temerity. When Nelson fought his battle in the Sound, it was the result alone that decided whether he was to kiss a hand at court or a rod at a court-martial. Charles Caleb Colton
success congratulations adversity
Constant success shows us but one side of the world; adversity brings out the reverse of the picture. Charles Caleb Colton
success achievement silence
Constant success shows us but one side of the world. For as it surrounds us with friends who will tell us only our merits, so it silences those enemies from whom alone we can learn our defects. Charles Caleb Colton
successful causes flourishing
The increasing importance of Sydney must in some measure be attributed to the flourishing condition of the colony itself, to the industry of its farmers, to the successful enterprise of its merchants, and to particular local causes. Charles Sturt
success eggs laziness
The goose that lays the golden eggs likes to lay where there are eggs already. Charles Spurgeon
system word
We feel that the system will get the word out when it's needed. Kevin Potter
systematic mental-illness institutions
The family unit is the institution for the systematic production of mental illness. Ashley Montagu
system weakness
There is a weakness in the system somewhere, David Hayes
systems
I think you'll see very aggressively priced systems out there. Paul Otellini
system
We've got to have just one system . . . it's a no-brainer. Lance Lyttle
systems weather
Fortunately, the weather did end up cooperating, and it's all systems go. Mike Claffey
systems-change consciousness individual
As one individual changes, the system changes. Ram Dass
system talking
There is no new system in place. I don't know what you're talking about. Bill Belichick
system
We need a better dredging system that we have now. Gary Anderson
teams
The other teams have left, and they're still not really back. We haven't left, and we're not going anywhere. Walter Leger
teams
We've already made the decision. Most teams put five, but we're going to put six. Alain Vigneault
teams three
When the three of us are on, we're really tough. There are not a lot of teams that can keep up with us when we play like that. Paul Davies
teams trying
We're just still searching, just trying to find out what teams are the best. Steve Rodecap
teams
Most teams that you have, they have one or two go-to guys. They've got a go-to team. Bernie Bickerstaff
teams top
Most of the teams at the top just didn't give up as much ground. Matthew Faltys
teams
When we started out as freshmen, we were ok, but there were other teams out there who were a lot better than us. Tyler Mitchell
teams travel
Many of them play on the same travel teams and know each other well. Marissa Chovanec
teams
SEC teams are going to make runs. That just happens. It's part of the game, man. Eric Ferguson
ties perfection mind
That alliance may be said to have a double tie, where the minds are united as well as the body; and the union will have all its strength when both the links are in perfection together. Charles Caleb Colton
ties looks bread
Bread is a second cause; the LORD Himself is the first source of our sustenance. He can work without the second cause as well as with it; and we must not tie Him down to one mode of operation. Let us not be too eager after the visible, but let us look to the invisible God. Charles Spurgeon
ties answers spirit
It is the cowish terror of his spirit that dares not undertake; he'll not feel wrongs which tie him to an answer. William Shakespeare
ties government secret
A reporter's ability to keep the bond of confidentiality often enables him to learn the hidden or secret aspects of government. Bob Woodward
ties people political
Often dismissed or underestimated by political opponents, President Reagan had the most valuable weapon in the political arsenal: a bond with the people. Bill Jenkins
ties security-guards security
I probably was as bad as a security guard as I was as a tie salesman. David Hyde Pierce
ties may belief
Disbelief in futurity loosens in a great measure the ties of morality, and may be for that reason pernicious to the peace of civil society. David Hume
ties government guarantees
We borrowed money, it helped us with bonds and what not, and the Federal Government backed it, but it was a guarantee, it was not a grant. And we not only paid it off, but we paid it off ahead of time. David Dinkins
ties shields hips
I wasn't born with a tie or with Mark Shields stapled to my left hip. I have another life. David Brooks
track signals familiar
How can I ever hope to communicate something to you unless I get signals back from you that I'm on the right track or that I've started at some place that you're familiar with? Alan Alda
track figures crosses
But no, we cross, crisscross, and recross our old tracks like figure skaters. David Mitchell
track racing special
Its always a little different, racing on your hometown track. It makes it more special. Buddy Rice
track together different
I like to piece together different guitarists, unlikely bedfellows. You have Jonny Greenwood playing next to Nile Rodgers on the same track, so it becomes like an orchestra of sounds. Bryan Ferry
track enjoy
I enjoy my life, I love track, I'm set for life financially. Carl Lewis
track income needs
You need a very good financial person to keep you honest, and to keep track of income and outgo. Bill Kurtis
track railroads green
I started composting in 1970 by taking my food scraps out behind where I lived and burying them in a hole next to the railroad tracks - and green things started to grow there! Ed Begley, Jr.
track albums easier
It is definitely much easier to feel that an album is disposable - to dismiss an album or delete the tracks you don't like or to just throw it into shuffle or whatever. Ed Droste
track long desire
So long as your desire to explore is greater than your desire to not screw up, you're on the right track. Ed Helms
watches nightmare film
It's a nightmare to sit and watch a film that I'm in. There's a horrible inescapability to it. Alan Rickman
watches culture ugh
I am so spoiled. I cannot watch a show where it gets interrupted for ads. I have to TiVo it and skip through the ads, because the culture of advertising is so false and phony that I just... ugh, you know? Alan Ball
watches looks like-you
How galling to watch someone who looks like you, who basically is you, do all the shagging you didn't get to do. David Tennant
watches hours skates
I could sit here in the tribunes and watch Michelle Kwan skate for hours... Carolina Kostner
watches instinct impress
When I watch species other than my own, their instinct's wisdom is what most impresses and disturbs me. Charles Lindbergh
watches lord caught
We boast in the Lord but watch carefully that we never get caught depending on Him. Aiden Wilson Tozer
watches disaster conversation
You don't have conversations with microprocessors. You tell them what to do, then helplessly watch the disaster when they take you literally! David Brin
watches trailers
I don't watch trailers, I like to go into every movie fresh. Benh Zeitlin
watches world
I have learnt how to live…how to be in the world and of the world, and not just to stand aside and watch. Audrey Hepburn