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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
ancient bringing foot life rest
We usually say of ancient persons, that they have already one foot in the grave, and the rest of their life is nothing else but the bringing of these feet together. John Pearson
ancient conjecture diana given originally portion rise temple
The Temple of Diana is in the vicinity of the fountain, which has given rise to the conjecture that it originally constituted a portion of the ancient baths. Marguerite Gardiner
ancient fell love monastery surrounded
I remember going to a monastery library when I was very young and being surrounded by ancient books. I fell in love. Hans-Ulrich Obrist
ancient ancient-history
I love Paris for its wide boulevards and cafes, and Rome for the ancient history, as seen at the Forum. Alan Titchmarsh
ancient move reason unless
Unless there's a reason to re-open ancient history, we should move on, Harvey Pitt
ancient arabic believed century greek hindus physical sought
Physical immortality is seductive. The ancient Hindus sought it; the Greek physician Galen from the 2nd Century A.D. and the Arabic philosopher/physician Avicenna from the 11th Century A.D. believed in it. S. Jay Olshansky
ancient both classical four greek heart learned love modern speak terms took
I would love with all my heart to be able to speak Greek, classical or modern or both. It is a beautiful language, both aurally and in terms of the intricacy of its construction. I took four semesters of Ancient Greek in college, but it's all rusted away now - and I never learned to speak it anyway. Sarah Monette
ancient conditions
If our inconceivably ancient universe even had any beginning, the conditions determining that beginning must even now be engraved in the atomic weights. Theodore William Richards
ancient codes common decisions derives distilled law life opponents purpose rather respect rules unchanged
Just as the common law derives from ancient precedents - judges' decisions - rather than statutes, baseball's codes are the game's distilled mores. Their unchanged purpose is to show respect for opponents and the game. In baseball, as in the remainder of life, the most important rules are unwritten. But not unenforced. George Will
bothering-you bother ifs
If something is bothering you, keep it to yourself. David Strickland
both discovery driven east finds fossil mary since understand
With the discovery of Zinjanthropus at Olduvai Gorge in 1959, my grandmother Mary Leakey pioneered the research in East Africa with my grandfather Louis. Many more spectacular fossil finds have since been made, both in Africa and elsewhere, by many researchers driven to understand our past. Louise Leakey
both since
Wendy and I both wanted kids, but since we were pushing 40, the clock was ticking. Lisa Cholodenko
both feed suffice
I care not to debate which came first, Islamism or anti-Muslim bigotry; suffice to say that both feed into each other symbiotically. Maajid Nawaz
both direct guess project serious
There is a healthy fraternal rivalry, but nothing serious and we both have been looking for a project to do together. I guess he may direct me in a project some day. Mackenzie Astin
both country english federal issue kinds language laws learn official people practical side state
The other side said (there are) 799 federal and state laws mandating the use of English. ... We would say those kinds of laws are not at issue here. I think that English is the official language of this country in a practical sense already. And I think that most people who come here both learn English and want to learn English. Richard Cohen
both checks dressing great knows reason rooms sit sound together worse
The other reason Rufus and I are great together is that we're both really lazy. The rehearsing, the sound checks -- he's actually worse than I am, and that's something. To get us to do anything other than sit in our dressing rooms is a challenge. Who knows what will happen? Ben Folds
both potential
The potential is unbelievable with both those girls. Duncan Chase
both huge potential sales
The potential is huge for them both in sales and production. Tarun Das
cannot conflicts parliament solved strengthen
We want to strengthen democracy. When conflicts cannot be solved in parliament they should be solved by citizens. Jaroslaw Kaczynski
cannot democracy island regime send signal strong surrounded
We want to send a strong signal to the regime in Swaziland that it cannot be an island surrounded by democracy in the region. Zwelinzima Vavi
cannot cause continue including received spur ted work
Much like the conservationists who previously have received the Audubon Medal, including Stewart Udall, Rachel Carson and Ted Turner, I realize that this recognition cannot be a cause to rest, but a spur to continue our work. Louis Bacon
cannot dream
You cannot kill a breeze, a wind, a fragrance; you cannot kill a dream or an ambition. Michel Onfray
cannot empty fathom good players souls stories tried whatever work
Players would empty their souls to me; you cannot fathom the stories I've heard, everything from the good to the bad. I tried whatever I could to work things out. Morgan Wootten
cannot choices choose deeply inspirational life today until
Until a person can say deeply and honestly, I am what I am today because of the choices I made yesterday, that person cannot say, I choose otherwise. Stephen R. Covey
cannot choice choices choose deeply otherwise today until
Until a person can say deeply and honestly, "I am what I am today because of the choices I made yesterday," that person cannot say, "I choose otherwise Stephen R. Covey
cannot clearer congress count domestic help house looking remedy totally white
We are looking to Congress, ... It is clearer than ever that America's domestic manufacturers cannot count on any help from the White House to remedy this totally unacceptable situation. Alan Tonelson
cannot ensure forget happened remember side
We are at their side as they suffer. One cannot forget what happened and one must remember to ensure it does not happen again. Felix Herrero
change begets
Change begets change. Charles Dickens
change integrity roots
He that has energy enough to root out a vice should go further, and try to plant a virtue in its place. Charles Caleb Colton
change begets
Change begets change. Nothing propagates so fast. Charles Dickens
change men rocks
Change begets change. Nothing propagates so fast. If a man habituated to a narrow circle of cares and pleasures, out of which he seldom travels, step beyond it, though for never so brief a space, his departure from the monotonous scene on which he has been an actor of importance would seem to be the signal for instant confusion. The mine which Time has slowly dug beneath familiar objects is sprung in an instant; and what was rock before, becomes but sand and dust. Charles Dickens
change country littles
If we strike a line to the N.W. from Sydney to Wellington Valley, we shall find that little change takes place in the geological features of the country. Charles Sturt
change age wells
It is not well to make great changes in old age. Charles Spurgeon
change becoming becoming-new
Everything is perpetually becoming new. Alan Watts
change way world
When you get free from certain fixed concepts of the way the world is, you find it is far more subtle, and far more miraculous, than you thought it was. Alan Watts
change vices computer
It is easier to change the specification to fit the program than vice versa. Alan Perlis
connects media music piece software
We're about deploying a piece of software that connects people. Our software is so much more than music or media. Steve Griffin
connects divisions expanding far forms great gulf islands largest separates three various
The Mediterranean Sea with its various branches, penetrating far into the great Continent, forms the largest gulf of the ocean, and, alternately narrowed by islands or projections of the land and expanding to considerable breadth, at once separates and connects the three divisions of the Old World. Theodor Mommsen
connects hear intangible lots regardless
We still feel there's something intangible that connects all the music. Lots of people, regardless of the song, can hear it and know that it's Gram Rabbit. Todd Rutherford
connects cover great truly
A truly great magazine cover surprises, even shocks, and connects in a nano-second. George Lois
connects difficult explosive forward goes nick player
Nick is an explosive player and it will be difficult to keep him off the pitch. He goes forward very well, dribbles well and connects with his teammates. Dana Taylor
connects dismiss funny involved music
I don't dismiss the music that I was involved with, I don't think it was a joke, I don't think it was funny or a phase, I don't think it was just something I was doing back then, to me it was who I am. It connects all the way through. I don't distance myself from any of it. Ian MacKaye
connects consensus continue course major national pursue reach sciences scientists social whether
That was the first major social sciences conference at which social scientists from all cultures wanted to reach a consensus on whether we can continue to pursue a national course in the social sciences or whether we need a cosmopolitan path that also connects us in a new way. Ulrich Beck
connects dabble love music projects side
I like to dabble in different things, but music is my first love. It connects to me in a way my side projects don't because it's so personal. I write the words. Music is like my diary. It's my therapy. Eve
connects environment finding landscape painter peace people
It connects with the soul. People connect with the environment and their surroundings and this painter really strove to do that with the landscape by finding the peace in it. Jessica Aiken
embrace melting moss point true
We are a true melting pot, and we made it work. It's really important that Moss Point embrace that idea. Kathy Murray
embrace life lived love moved west wherever
Wherever I am, I will embrace the life and the lifestyle. I've lived in Hollywood before, and we've moved into the old neighbourhood in West Hollywood. I love California. John Barrowman
embraced people surround turned
Where some people were bemoaning some of these things that surround the program, I think he has embraced them and turned them into positives. Pat Haden
embrace good hit quick time
Embrace good smells. No cost, no calories, no energy, no time - a quick hit of pleasure. Gretchen Rubin
embrace genre supervisors
As a music supervisor, you learn to embrace the best of every genre, and I really have to say there's nothing that I'm embarrassed of. Alexandra Patsavas
embrace heads men side turn women
When I get dolled up to go out, men turn their heads and I'm used to it. But I think all women are sexy and should embrace that side of themselves. Malin Akerman
embraced foster girls
Luckily, our girls have embraced foster care. They like new people. Suzy Buchholtz
embrace gets life
Life gets better when you embrace your geekiness Rose McGowan
embraces heart suffer words
The pope, in his heart and with his words of encouragement, embraces all who suffer injustice. Pope John
modern poet should
How many modern transsexuals are unacknowledged shamans? Perhaps it is to poets they should go for counsel, rather than surgeons. Camille Paglia
modern apprentice
The modern technologist is less 'sorcerer' and more 'sorcerer's apprentice'. Barry Commoner
modern
I would like to do something modern and possibly funny. Dan Stevens
modern solutions
It is a Modern day, and these times need Modern solutions to Modern problems. Corin Nemec
modern-life plumber ifs
If I had it [life] to do all over again, I'd have been a plumber. Albert Einstein
modern outside presidency turned
When a presidency has been turned around, particularly the modern presidency, there's often an outside element. Fred Greenstein
modern presented words
There are no four-letter words or vulgarity. It's got modern themes, but they are presented in an old-fashioned way. Sally Deering
modern people
I don't think people want chains. People want modern conveniences, but they don't want chains. Dean Miller
modern success tolkien
The success that the Tolkien books had redefined modern fantasy. George R. R. Martin