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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
classes field forth retiring talked together took trips
We were back and forth together and our classes took field trips together. We've even talked about retiring together. Debbie Miller
classes house people reminded talk talked time whenever
Whenever she's around you're pretty much happy. She'd come over to my house between classes and I'd take her to class. We'd just talk. I told her all the time she reminded me of my sister. There aren't many people I could talk to like I talked to her. Adam Carr
classes found meetings practice rolling schedules stones
We found out why the Rolling Stones don't have a day job. Meetings and classes and conflicting schedules chews up a lot of practice time. John Sherry
classes taken
Yes, and we've already taken all the classes and shots. Dixie Aiazzi
classes compete couple difficult events field focus home individual majority monday night prepared saturday stay team travel
We're just going to focus on individual events this weekend. The majority of the team will travel home Saturday night after the individual events, while a couple of the field event competitors will stay to compete Sunday. It makes it difficult to compete in the relays on Sunday, travel home and be prepared for classes Monday morning. Robert Ford
classes good learned people university
I worry that people think you have to go to a university to be a good writer, which is categorically untrue. I don't think I learned how to write at Oxford. I did not go to any creative writing classes or anything. Samantha Shannon
classes glad living strange teach telling
I don't teach writing classes anymore, and I'm really glad I don't, because I would feel very strange about telling people, 'Go out there and be a writer, and make a living from it.' Ursula K. Le Guin
classes demands full meet move system
We had been at full capacity. Now we could unfreeze the system and move classes around to better meet demands on the campuses. Michael Beals
classes demands full meet move system
We had been at full capacity, ... Now we could unfreeze the system and move classes around to better meet demands on the campuses. Michael Beals
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
high junior played president schools york
I was president of the schools in junior high and high school, got a scholarship to New York University, played a little basketball, and was a celebrity. Louis Gossett, Jr.
highly regarding requests side
The other side has not responded to any of our requests regarding the abduction issue, so it is highly regrettable. Shinzo Abe
high potential profits
The potential profits are so high there's a win-at-any-cost mentality. James Browning
high models perception prices support
The perception is that it's too high end, too futuristic, but I think we will see prices and use models to support it. Mark Thompson
highest income leave north pay people simply tax
The people who pay the highest income tax are also the most mobile. They simply leave North Carolina. John Connaughton
high trying unique yorkers
We are always trying to look for unique ideas, and we wanted something new for New York. We thought that hey, it's an island, let's do something on the water...New Yorkers have pretty high expectations. John Remington
high large previous risk state
We've always been on a high state of alert. The perpetrators of the previous bombings are still very much at large and the risk is still very much with us, Marty Natalegawa
middle outside prevent shots struggled
We struggled to clog up the middle and prevent shots from outside the 18. Lance Lattin
middle sentences
Rabo Karabekian: I'm in the middle of a sentence. Circe Berman: Who isn't?. Kurt Vonnegut
middle-east dove making-peace
It takes more than one dove to make peace in the Middle East. Madeleine Albright
middle principal school work
When I was a middle school principal it disgusts me, some of the things I had to work through at that young age. Randy Simmons
middle nowhere rural singing songs whether
I think my songs are singing to the rural heart. It's not whether you're from a big city or the middle of nowhere in a small town. Rodney Atkins
middle ends get-involved
I get involved in the beginning, less in the middle, and very much at the end. Diane Sawyer
middle knows capable
Everyone tells us you really don't know what you're capable of till you're in the middle of it. Anthony Rapp
middle-east east middle
Syria is geographically and politically in the middle of the Middle East. Bashar al-Assad
middle points treat
We treat it no differently than a rainout in the middle of the season. We never make up a points race. Jiggs Thomason
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
school figures ifs
You can't figure out the Universe, especially if you're using figures to figure it. Alan Watts
school hard-work church
But perhaps when you were too obedient, and did not do openly what others did, and were quiet in church and hard-working at school, then some unknown rebellion brewed in you, doing harm to you, though how I do not understand. Alan Paton
school age taught
I've never studied anything formally. I was excluded from school at the age of 17, so I am an autodidact, which is a word that I have taught myself. Alan Moore
school opportunity thinking
I don’t think people realise how vital libraries are or what a colossal danger it would be if we were to lose any more. Having had a truncated school life myself, all of my education from the age of 17 has been self-taught. I wouldn’t be the person I am today if it wasn’t for the opportunities the library gave me. Alan Moore
school ideas forgotten
I've never forgotten that experience. But I had nobody at school that was either like Hector or Irwin. The masters had no idea what was expected of you in the scholarship exam, so you just had to busk it really. Alan Bennett
school boys oxford
My experience came before most of you were born. My school was a state school in Leeds and the headmaster usually sent students to Leeds University but he didn't normally send them to Oxford or Cambridge. But the headmaster happened to have been to Cambridge and decided to try and push some of us towards Oxford and Cambridge. So, half a dozen of us tried - not all of us in history - and we all eventually got in. So, to that extent, it [The History Boys] comes out of my own experience. Alan Bennett
school care students
I'm 53. I don't care about high school students. I find them irritating and uninformed. Alan Ball
school exercise keys
Musicals are hard for me because I got thrown out of the glee club in high school, because I couldn't sing in tune at the time. I can sing in tune now, but I have to work really hard on it to make sure that I don't exercise one of my great talents, which is the ability to sing in three keys at the same time. Alan Alda
school thinking lasts
When I studied how to think in school, I was taught that the first rule of logic was that a thing cannot both be and not be at the same time and in the same respect. That last note, “in the same respect,” says a lot. As soon as you change the frame of reference, you’ve changed the truthiness of a once immutable fact. Alan Alda
telling-the-truth mood foul
I prefer you like this, when you're in a foul mood, because you tell the truth. Carlos Ruiz Zafon
telling
I'm really into the idea of telling stories. Everyone needs stories. Everyone needs to escape every once in a while. Luke Bracey
telling
When you're young, you think you can do anything, and that was really a gift. That's why I can never understand someone telling me 'no' today. 'No' just isn't an option. Sandra Lee
telling-the-truth caution
It requires as much caution to tell the truth as to conceal it. Baltasar Gracian
telling
Magicians will always tell you the trick is the most important thing, but I'm more interested in telling a story. Marco Tempest
telling
The stammer was a way of telling the world that he was not like others, a way of expressing his singularity. Ted Morgan
telling
Singing is about telling a story. When you are onstage, you get to be your own self... When acting, you're someone else. Sabrina Carpenter
telling
What I am telling you is that Matta had a way of making you feel comfortable and that's probably why he had nine wives because he made them feel comfortable and then uncomfortable later. Robert Barnes
telling
Any story that I can consider worth telling is one that you could tell in words. Ira Glass
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
trying sometimes failing
Try to do unto others as you would have them do to you, and do not be discouraged if they fail sometimes. It is much better that they should fail than you should. Charles Dickens
trying want scripture
Dear friends, whenever you want to understand a text of Scripture, try to read the original Charles Spurgeon
trying littles reason-why
The great reason why we have so little good preaching is that we have so little piety. To be eloquent one must be in earnest; he must not only act as if he were in earnest, or try to be in earnest, but be in earnest. Charles Spurgeon
trying world term
A myth is an image in terms of which we try to make sense of the world. Alan Watts
trying world
But we try to pretend, you see, that the external world exists altogether independently of us. Alan Watts
trying way hurrying
Hurrying and delaying are alike ways of trying to resist the present. Alan Watts
trying rooms natural
That Beatle euphoria has always been there, and it's hard to be in a room with a Beatle and try to be totally natural. You never shake that off. Alan Parsons
trying entertainment television
I try to do things in comics that cannot be repeated by television, by movies, by interactive entertainment. Alan Moore
trying acting together
Improvisation sometimes seemed more like jazz than acting, like verbal jazz, with the actors playing a theme back and forth, and then introducing another theme, incorporating it, somehow trying to work their way all together to a meaning of some kind, or at least a conclusion. Alan Arkin