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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
bad-day men dc-comics
All it takes is one bad day to reduce the sanest man alive to lunacy. That's how far the world is from where I am. Just one bad day." The Joker - The Killing Joke Alan Moore
bad-day self abuse
If I was having a bad day, eating was like self-medicating. But if you abuse food, you still have to use that substance that you abuse every day. You have to learn to use it responsibly. Al Roker
bad-day giving lazy
The only bad days as a writer are the ones when you are too cowardly or too lazy to sit down at the keyboard and give it everything you have. Chris Cleave
bad-ass thinking done
Designers think everything done by someone else is awful, and that they could do it better themselves, which explains why I designed my own living room carpet, I suppose. Chris Bangle
badass agency views
It is easy to romanticize poverty, to see poor people as inherently lacking agency and will. It is easy to strip them of human dignity, to reduce them to objects of pity. This has never been clearer than in the view of Africa from the American media, in which we are shown poverty and conflicts without any context. Chimamanda Ngozi Adichie
bad-ass bayonets ass
Where the hell do you put the bayonet? Chesty Puller
bad-mood mood
When I'm in a bad mood, I don't listen. Cathy Freeman
bad-relationship mice
I have a very bad relationship with mice. Casey Affleck
bad
You know, conservatism is not a bad thing. It's not a pejorative. Michael Steele
feels students university
We want to show how the university feels and show how the students feel and see how much of that is really true. Adam Allen
feels
I never feel as though I'm ever, ever alone. Chita Rivera
feels japanese-food
Japanese food makes me feel particularly good. David Mitchell
feels i-can
I don't intend to stay around any longer than I feel I can be No. 1. Carl Lewis
feels time
We've all put so much time in, and it's what we deserve. It's an unbelievable feeling. It feels great. Josh Brown
feels game hearts imagine played
We've all played this game and had our hearts broken. I can only imagine what it feels like at this level. Geoff Blum
feels free good life meditation mode moment retreat train weekend
We're in a mode where it feels like there's no free time, but there really is. To live a good life is not about going to a meditation retreat one weekend a year. It's about moment by moment, every day. You've got to train yourself, train yourself to be calm. Darrin Zeer
feels few guess number trend weeks
Where I would have thought this was 30-70 or 40-60 a few weeks ago, my guess is it feels more like 50-50 now, which is not just a number but a trend line. Rick Anderson
feels
C'est vrai. Voilá quelqu'un qui sent comme moi. (It is true. There is someone who feels as I do). Edgar Degas
greatness men mind
Great men, like comets, are eccentric in their courses, and formed to do extensive good by modes unintelligible to vulgar minds. Charles Caleb Colton
greatness deserving-it mind
Great minds had rather deserve contemporaneous applause without obtaining it, than obtain without deserving it. If it follow them it is well, but they will not deviate to follow it. Charles Caleb Colton
greatness men
In life we shall find many men that are great, and some that are good, but very few men that are both great and good. Charles Caleb Colton
greatness men too-much
Speaking generally, no man appears great to his contemporaries, for the same reason that no man is great to his servants--both know too much of him. Charles Caleb Colton
great-expectations secret tears
The secret was such an old one now, had so grown into me and become a part of myself, that I could not tear it away. Charles Dickens
great-expectations strange melancholy
So new to him," she muttered, "so old to me; so strange to him, so familiar to me; so melancholy to both of us!... Charles Dickens
great-expectations may done
But, in this separation I associate you only with the good and I will faithfully hold you to that always, for you have done far more good than harm, let me feel now what sharp distress I may. Charles Dickens
great-expectations may let-me
Let me feel now what sharp distress I may. Charles Dickens
greatness excellence littles
True greatness consists in being great in little things. Charles Simmons
lost-friendship sinister motive
Our very best friends have a tincture of jealousy even in their friendship; and when they hear us praised by others, will ascribe it to sinister and interested motives if they can. Charles Caleb Colton
lost
The gospel is not for you who can save yourselves, but for those who are lost. Charles Spurgeon
lost ability nations
When trust is lost, a nation's ability to transact business is palpably undermined. Alan Greenspan
lost left-behind behinds
And I'm lost behind The words I'll never find And I'm left behind As seasons roll on by Chris Cornell
lost-friendship sides asphalt
If he'd just crowded me down to the side of the asphalt, I'd have been OK. But when he ran me completely off the racetrack, I lost it. Cale Yarborough
lost
When you've lost something, and you find it again, it has so much more meaning. David Castillo
lost price safety
When you've lost a son, there's no price you can put on safety for the driver. Kyle Petty
lost said
You're not the same as you were before," he said. You were much more... muchier... you've lost your muchness. Lewis Carroll
lost credibility virginity
Credibility, like virginity, can only be lost once and never recovered. Charley Reese
ncaa potential risk
The potential here is significant. The NCAA is at some risk. Gary Roberts
ncaa tournament win won
We're in the tournament to win it all. We won the SEC tournament, and now we want to win the NCAA tournament. Corey Brewer
ncaa prepared ready
We're ready to go and we're prepared for the NCAA Tournament. Mike Nardi
ncaa ourselves playing reason score t
We are never going to give up and we're never going t look at the score and give ourselves a reason for not playing hard. We're playing to get into the NCAA tournament. Terri Mitchell
ncaa nobody players talks
Nobody talks about the NCAA Tournament, not the players or coaches. Only you guys. Richard Midgley
ncaa officials seen surprised
I don't know that we've seen it. But the NCAA surveys everybody. I'm not surprised they surveyed the officials about us. Mike Schulze
ncaa obviously tournament
I don't know where we're going, but you've got to look up. The NCAA tournament obviously is in jeopardy. If we want to be there, then we've just got to play. Eric Devendorf
ncaa single win
To feel like we're set for the NCAA Tournament, we have to win every single game. If we don't, we're going to feel like we're on the bubble, and we don't want to be in that position. Rahshon Clark
ncaa pressure tournament worry
We can go into the (Big Ten) tournament without any worry about the NCAA tournament. There's no pressure on us. Adam Haluska
proud not-sure be-proud
I'm not sure I enjoyed doing [Gigi Does It]. I'm cool with just being an actor. If anything, I learned to be proud of being an actor. David Krumholtz
proud firsts british
I was the first woman British commissioner, the first woman trade commissioner, so I am also proud to be the first woman High Representative. Catherine Ashton
proud littles looks
Respect me. Be proud, and if you love me, a little afraid, because love so often looks like fear. We are alike. We are alike. Catherynne M. Valente
proud salary teachers
We are proud we can give teachers the kind of salary we do. Vickie Simmons
proud since striving
We are proud of the improvements that we have made since 2004. We are going to keep striving to do better. Justin Glover
proud
We are proud of the effectiveness of our procedures. Stefan Pryor
proud work
We still, obviously, have a lot of work to do, but I'm proud of them. Chad Bankston
proud share knows
Tis beauty that doth oft make women proud; but, God He knows, thy share thereof is small. William Shakespeare
proud done decided
When I decided to direct, never having done that before, is something I'm very proud of Ed Harris
seasons
I will never have my best season. Brian Dawkins
season six wonderful
Six and five, ... We thought 6-5 would be a wonderful season for this team. Steve Spurrier
season
We've still a lot to do before the season starts. Richard Walker
season
She's been killing it all season and is only getting better. W. S. Gilbert
season
The PD is over now. We've got a new season to play now, and we need to go 3-0 to get to where we want to be. Walter Brower
season
(We) still have a lot to accomplish. That's something to think about when the season is over. Derrick Brooks
season second worked
I worked with her on the second season of Dark Angel in Vancouver, one of my first real jobs. Ashley Scott
season seasons tale
This season has really been a tale of two seasons for me, Ricky Ford
season
We didn't come out to play, we didn't come out with any urgency. We've got to do better because, if we do this in the playoffs, the season is over. Dema Kovalenko
tournaments
I never learned a thing from a tournament I won. Bobby Jones
tournament win
We're in the tournament to win it all. Corey Brewer
tournament
Were in the tournament now, and in the tournament anything can happen. Mike Conners
tournament work
We've still got a lot of work to do. The bye is nice, but we've got to go play come tournament time. Tom Herrion
tournament
Lennart is getting better. This tournament is part of his recovery. Peter Wright
tournament
If accommodations have to be made, they'll have to be made in how the tournament is scheduled. Gary Bettman
tournament win
I think we've got to win this tournament just to go to the NIT. Mike Carey
tournament truth
This tournament doesn't tell the truth about major-leaguers. Stan Javier
tournament
I think the tournament MVP is going to come out of that bracket. Jared Esala
twice
I am very disciplined with my skin - I tone and I moisturize my skin twice a day. I also exfoliate, and I try to get a facial, like, once every two months. Grace Gealey
twice year
We come up every year once or twice a year. Dave Lewis
twice weight work
Well, being 6' 5', pull-ups are my nemesis. I have really long arms so I have to do twice the work of someone with short arms to get the weight up there. Joe Manganiello
twice
Black unemployment is twice white unemployment and has been for decade after decade. Rand Paul
twice
I've never had that before, in how many years of coaching? So we've had it twice in two games, so we've got to get that squared away, too. Vic Koenning
twice win
The win wasn't important for me, it was important for the team, ... But getting the win is twice as nice. Phil Jackson
twice
It was 1989, and there was a big brouhaha that he was so old and so gray. Now, we wouldn't think twice about it. Aaron Krach