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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
asked reason
The only reason why I know is because I get asked all the time. Darin Schreck
asked definitely
The person we interviewed is definitely the person we got. He's real. He's doing everything we asked to do. Ron Beck
asked bank money people star
The people who got star loans, they just went to the bank and asked for a loan, so they didn't take away in any way money someone in New York. Raul Cisneros
asked court courts forced pleased supported talk
We are pleased with this decision. We asked them to talk to us when they made this change, and they wouldn't. That forced us to go through the court system. And yet again, the courts have supported our position. Lee Huenecke
asked leave leaving listening people
We've always asked people to leave earlier, but because of Katrina, they are now listening to us and they're leaving as we say, Ann Thomas
asked talking
We started talking and half-jokingly, I think, I asked if he would be in (the movie), and he said 'Yeah, I could do that,' Gary Woods
asked ball invites knocked nobody president weak
If the president of the college had asked me what I thought about Dewey McLean, I'd say he's a weak sister. I thought he'd been knocked out of the ball game and had just disappeared, because nobody invites him to conferences anymore. Luis Walter Alvarez
asked autographs embarrass festival hope natalie signed
I've signed autographs as Natalie Portman. I was at a Film Festival party where someone asked if I was her, and I didn't want to embarrass them, so I signed the autograph as her. I hope she doesn't mind. Liane Balaban
asked brothers guy looked scientists similar theme three truck whether works
We actually got it from a guy that works at a U-Haul truck place in Berkeley. He thought that the three of us all looked very similar to one anotherwe all had on glassesand he asked whether we were all brothers and we said no and he asked whether we were all scientists. We said that we were not, but that was the theme of the name. Chris Cain
ball call force gary high pass percentage pull run stuff throw trying
We want to throw high percentage stuff this year, but it's like I told Gary the other day, if we call a pass and it's not there, pull the ball down and run with it and we'll come back and call another play. We just don't want him trying to force things and make mistakes. Gary Owens
ball grocery happen
We want to show that we're just like our neighbors. We go to ball games, we go to the grocery store, we go to church. We just happen to be Democrats. Sam Allen
balloons morality graves
Morality only is eternal. All the rest is balloon and bubble from the cradle to the grave. David McCullough
ballet lessons negative
You get more negative reactions than positive reactions as you go through life, and the big lesson is nobody counts you out but yourself...I never have; I never will. Buddy Ebsen
ballet rising world
Ballet is the body rising. Ballet is ceremonial and hieratic. Its disdain for the commonplace material world is the source of its authority and glamour. Camille Paglia
ballet theatre opera
Cricket is first and foremost a dramatic spectacle. It belongs with theatre, ballet, opera and the dance. C. L. R. James
ball football intent intention kid point ran supposed turning
The other thing that killed us was that punt. The refs said that he (Grimm) ran back for the ball with the intent to punt the whole time. How's our kid supposed to know that that this guy's intention is to punt? That was the turning point in the football game. Eric Foust
ball company easy few gigantic last money performance pot smaller time turn
The performance of the company over the last few years has been very erratic. It's also a smaller player. It was time for Milstein to take it easy and make a gigantic pot of money and turn the ball over to someone else. Howard Davidowitz
ball care clear difference games point position possesses winning
The point I've made very clear to him, and I made very clear to you: You will not play quarterback or any other position that possesses the ball for me. You have to take care of the ball because it's the difference between winning games in this league. Marty Schottenheimer
david struggle type
We're in a David and Goliath type struggle, and we're David, ... And David won, as we all know. Scott Moore
david help interested needed persons time whom
David Bruce, I think, is one of the outstanding persons for whom I've ever worked. He had a sense of balance. He was interested in everything that went on in the Embassy. He delegated authority, but at the same time when you needed the Ambassador's help on anything, you could go to him, and he would immediately respond. Hermann Eilts
david defined met nobody performance peter rare saw success whose
I never met Peter O'Toole, but he one was of those rare actors whose success was defined by a single role. His incandescent performance in David Lean's 'Lawrence of Arabia' is one that nobody who saw it will ever forget. Michael Korda
david preparing
When I was preparing for the film for tree weeks, with David Cronenberg, I had a lady friend come over. John Lone
david fear gay people status threat throughout
Throughout history, gay people such as myself and David have often been made scapegoats by those who fear that we are a threat to the status quo. Elton John
david pause people terms
It's easy to see why 'American Horror' is freaking people out. The ultraviolent hallucinations never pause long enough to make sense. In terms of coherence, it makes your average David Lynch movie look like 'Burn Notice.' Rob Sheffield
david love rap
David Bowie's my favorite musician. I love him above all, but I'm really into rap a lot right now. Ethan Suplee
david far grew jerry knew letterman performance
I grew up loving David Letterman and Pee-wee Herman, but as far as live performance comedy, all I knew were the Jerry Seinfeld-type comedians of the world, and that's what I thought live performance comedy was all about. Scott Aukerman
david needed threw
We needed a big play. I threw it up, David go under it touchdown! M. Wolfe
delighted
I voted for Obama and I was delighted that he's been elected. Bill Ayers
delighted europe european great grew offered partly until
I live in New York, but I am always delighted to come to Europe because I am European and grew up here until I was 20. I am not only Italian, I am partly Swedish. When my parents divorced, I was three years old and went to live in Paris... when I am offered a film in Europe, I come with great enthusiasm! Isabella Rossellini
delighted maybe totally
So I think the fans will be totally interested in the new developments and delighted that the old developments are still there and that they can still see some of the old characters maybe reappear. Andreas Katsulas
delighted liked marks question rolls run
She's run very well and, in a sense, we are delighted because there were little question marks after Dubai. I liked the way she accelerated. The story rolls on. Ed Dunlop
delighted indians mumbai sure
We are very happy to have Sachin as the Mumbai Indians Icon. I am sure the youngsters in the team will be delighted to have him around for guidance, and so would be the Mumbai Indians fans. Nita Ambani
delighted joined
We are delighted that Keith has joined our team. Brian Kelley
delighted flag flying july
We are delighted that he will be flying the flag for us on July 6th. Sebastian Coe
delighted streets warm welcome
We are delighted for them. It really will be a life-changing experience. They really will be getting a warm welcome on the streets of London. Dan Kirkby
delighted hard paid work
We are delighted - a lot of hard work has paid off Sebastian Coe
easy monopoly legislation
I'm not denying that monopolies are terrible things, but I am denying that it is readily easy to resolve them through legislation of that nature. Alan Greenspan
easy crosses lays
Be hard on yourself and easy on others. Carry your own cross but never lay one on the back of another Aiden Wilson Tozer
easy easy-things
Americans really don't understand the Japanese nature, but it's not an easy thing to understand. Cary-Hiroyuki Tagawa
easy it-takes-time take-time
Change isn't easy, it takes time. Caroline Kennedy
easy hard
Things are so easy to do, so hard to undo. Catherine Ryan Hyde
easy fight leaving problem ready union work
The percentages are low, no question, ... The work is leaving the workers. This outsourcing is a problem for union and non-union workers. Labor's never had it easy but we're ready to fight for workers' rights. Jack Shea
easy faces game half knew second stay stops tough
We started the game with stops and conversions, and we started the second half with stops and conversions. ? We knew we had to make it tough for them to score. We had to stay in their faces all night. No easy baskets. Louis Orr
easy struggled
We struggled through it, and nothing ever comes easy for us. Frank Robinson
easy embark feeling feels felt harder keeps knew might since time toes whenever
The more I act, the harder it gets, since I feel like I still have so much to learn. Whenever I embark on a new project, it always feels like the first time. If it were easy to me and I felt like I knew everything, my acting might have been different. I think the feeling of 'newness' keeps me on my toes and concentrated. Lee Byung-hun
gives
The person who gives is a person who has Lithuanian Proverb
gives good happy identify means positively school winning
We are pretty happy about winning a championship. It's always good when you win a championship. It means that you have represented your school well and gives the school something that you can positively identify with. Pedrito Estrill
gives hope perform plug point position road stronger win
We're in a position where we can look years down the road and plug in other things. I think that gives us hope for a stronger future. Now, they've got to win and perform well and all that stuff, but you've got to get yourself to that point where we are now. Dave Littlefield
gives good opportunity practice rested
We're in a good position, but we still have to go out there and compete. At least this gives us an opportunity to practice and go over some things and get rested up for Friday. Ashley Burnett
gives preach virtues wealth
Wealth is what gives you the right to preach about the virtues of poverty. Source Unknown
gives inventory room smaller
We have a smaller showroom than a lot of other dealerships. That gives us room for more inventory (on the lot). Mike Donahue
gives hurting message player sends
When you see a player go down like that and is really hurting and can't come back, I think that sends a message to our team. It gives you fire. David Booth
gives main portion remove room
We're going to remove that portion first because it gives us more room to remove the main portion. John Hanley
gives size
We're going to need him. He gives us more size out on the perimeter. Jay Wright
player games profound
As in the game of billiards, the balls are constantly producing effects from mere chance, which the most skillful player could neither execute nor foresee, but which, when they do happen, serve mainly to teach him how much he has still to learn; so it is in the most profound and complicated game of politics and diplomacy. In both cases, we can only regulate our play by what we have seen, rather than by what we have hoped; and by what we have experienced, rather than by what we have expected. Charles Caleb Colton
player sight league
It's important that top clubs don't lose sight of the fact that it's the English Premier League and English players should be involved. Alan Pardew
player nhl cities
I played with Joey Mullen back in Salt Lake City before he got called up to St. Louis. He was the first player ever to score 20 goals in the American League and 20 in the NHL. I've kept in contact with him and he's a great guy. Alain Vigneault
player league different
All of a sudden I'm in the major leagues and we're traveling from town to town. I see the other players dressing different every day. I've got only one suit and I keep wearing it over and over. I'm really embarrassed. Al Kaline
player long stylist
In my opinion, Louis Armstrong is the greatest trumpet stylist of all time and has influenced every trumpet player of his time and long after Al Hirt
player thinking long
I think I earned the players' respect, and that's the ultimate in life, isn't it? I didn't care if they liked me or disliked me, as long as I had their respect. Al Barlick
player dictator guilty
Once again, as a flawed evaluator of dictators and failed strategist who has permitted Russia back in as a major player in the Middle East, is Hillary Clinton guilty or not guilty? Chris Christie
player trying being-the-best
I'm just trying to be the best player that I can be. Chris Bosh
player games watches
When you're not in the game, you can watch. Certain players have mannerisms, and they do the same things repetitiously. Chris Bosh
praise good-things should
Good things should be praised. William Shakespeare
praise prove
Praise us as we are tasted, allow us as we prove. William Shakespeare
praise increase
We increase whatever we praise. Charles Fillmore
praise creation increase
We increase whatever we praise. The whole creation responds to praise, and is glad. Charles Fillmore
praise standards higher
Praise invariably implies a reference to a higher standard. Aristotle
praise strikes strokes
Thy praise or dispraise is to me alike; One doth not stroke me, nor the other strike. Ben Jonson
praise tis words
Tis better that a man's own works, than that another man's words should praise him L. Estrange
praise neglect mansfield-park
that you seemed almost as fearful of notice and praise as other women were of neglect. (Edmund to Fanny) Jane Austen
praise tend throw upbeat
I'm a pretty upbeat guy. I tend to throw a lot of praise around. Joe Girardi
rarely
I don't wear perfume, and I rarely wear jewelry. Karina Lombard
rarely
Rarely ever see or meet the writer during shooting. Tom Skerritt
rarely
When in doubt, one can rarely go wrong by going public. James E. Rogers
rarely
I'm a believer in the polls, by the way. Rarely do you see a poll that's very far off. Donald Trump
rarely
Very rarely is there any confusion as to when a painting or a song is finished. You just know when it's done. Brandon Boyd
rarely
I very rarely think in words at all. A thought comes, and I may try to express it in words afterwards. Albert Einstein
rarely
I rarely in a working day go more than 10 minutes without looking at Slack. Stewart Butterfield
rarely slogans troops
Slogans rarely convince the unconvinced. However, they do rally the troops already on your side. John McCarthy
rarely women
You rarely see women being nice to each other on television anymore. Aisha Tyler
roles guru shows
The role of the Guru is to show the person that he already has what he is looking for. Alan Watts
roles mayors convinced
I am convinced that your Mayor must take the leadership role in education too. Alan Autry
role-models people trying
I'd like to be the role model to teach other people who have Down's syndrome to be actors and actresses and to be themselves and not try to be a big shot. Chris Burke
roles
You go up for hundreds, thousands of roles, and you get told no, no, no, so many times. Chloe Grace Moretz
role-models community leader
Companies and leaders are role models - not just with the business community - but in the broader world. Chip Conley
roles
I choose my roles carefully. Catherine Deneuve
roles
I take away something from every role. Cary Elwes
roles life-is stills
I take away something from every role. I'm still learning and that's what life is about. Cary Elwes
roles money-in-politics wells
Well, the role of money in politics is pretty corrupting right now. Caroline Kennedy
special trophies ifs
If everyone is special, then no one is. If everyone gets a trophy, trophies become meaningless. David McCullough
special records world
It's something special to break the world record at the Olympics. David Rudisha
special routine crime
Like Richard Price and the late, great Elmore Leonard, Matt Burgess is one of those cool, quick and funny writers who can turn a seemingly routine crime caper into something special. Carl Hiaasen
special
Everyone tells you how they are going to be "special", but few do the work to get there. Do the work. Mark Cuban
special radio fascination
As far back as I can remember, the radio held a special fascination for me. Charley Pride
special realizing results
Beauty is the result of realizing what is special about you and not focusing on the things you don't like. Bobbi Brown
special scripts actors
I'm not one of these actors who can make a bad script good. Some actors, a script can be terrible, and they can bring something to it and make it really special. I can't. Eddie Marsan
special progress tools
There is not a tool, an implement, or a machine that has not resulted in a decrease in the contribution of human labor. Labor is not made permanently idle [though]; when replaced in one special category... it turns its attack against other obstacles on the main road to progress. Frederic Bastiat
special used call-me
Jim Cameron used to call me 'Special Ed.' Edward Furlong