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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
confident everybody
We are pretty confident everybody will be back tomorrow. Mark Klein
confident good
We acknowledge they're a good team. But we know we have a good team, too. I feel confident about our chances. Chris Jones
confident group lucky matter open plan
We always have a Plan B, and we're working on a C and D. We are confident we're going to find someone. All the ingredients are here. It's just a matter of what lucky group will open the store. Rob Dickson
confident guys hold qualify state
We want to qualify as many guys for state as we can. If we can do that, I'm confident that we can hold our taper for another week. Todd Wuerger
confident forward looking telling
We have a story to tell, and we're looking forward to telling it and we're very confident how it's going to come out. Dan Petrocelli
confident solution
We have a solution that fixes the problem, and we're confident that this is going to be the right remedy. Kristen Kinley
confident defense great solid
We have a solid defense and a solid keeper. She made some great saves. I'm really confident in my keeper. Nikki Green
confident evidence fairly feathers primitive
We have no evidence of feathers in this species. But there is evidence of feathers in another primitive tyrannosaur. We are fairly confident that it did have feathers. James Clarke
confident defend feeling good knowing leave people session
We want people to leave here after a session knowing they got a good workout, feeling confident and able to defend themselves. Daniel Gaul
driving truck inns
Childbirth, as a strictly physical phenomenon, is comparable to driving a United Parcel truck through an inner tube. Dave Barry
driving force activism
Activism has always been the driving force for change. David Swanson
driving love soon together
We started driving around together as soon as we got our licenses. We love to drive. Nick Pisca
driving experience jump lost precious sudden turned upside
This sudden jump turned her driving experience upside down and her whole world upside down. She lost the most precious thing there was to her. Her intoxication had nothing to do with that. Elbert Hatchett
driving factors market nice reminder step
When you step back and put it all together, it's nice timing. It's a New Year's reminder of the geo-political factors that are driving the market higher. Mike Wittner
driving easy interstate
It's not supposed to be easy. It's not supposed to be driving down the interstate. Carl Edwards
driving girls help run
When you run with those girls every day, you can't help but get better and that is what is driving them. Tracy Harris
driving home safely
We want everyone to get home safely who may be impaired from driving for any reason. Bob Krueger
driving hurricane imagine looked loss months six
When we were first driving through the town, I was at a loss for words. It looked like the hurricane had just come through the day before we got there. I can not even imagine what it looked like six months ago. Ryanne Floyd
efficiency graduated highest lost next passing won
The other thing I would say about Vince Young is he just had the highest passing efficiency of any quarterback in the country. We're very complicated with what we do offensively, and he's won 30 and lost two. He would have graduated next fall. Mack Brown
efficiency efficient qualities sorts
There are only 2 qualities in the world: efficiency and inefficiency, and only 2 sorts of people: the efficient and the inefficient. George Bernard Shaw
efficiency pace stories telling type
I had just come off doing a lot of commercials when I did 'Go,' so a part of the fast pace and efficiency comes from the discipline I had to learn from telling stories in 25-second increments, and that type of discipline is insane. Doug Liman
efficiency information mourning rates survival
We need better information on survival rates and recruitment rates of mourning doves. But we have to look at the availability and efficiency of non-toxic shot. Jay Roberson
efficiency experts favor laid
If all efficiency experts were laid end to end- I'd be in favor of it Al Diamond
efficiency score
Efficiency is anything that scores. Bruce Lee
efficiency good hardest job offense passing
He's done a very good job as a leader. One of the hardest things to do on offense is be consistent, and he's really done a good job. His passing efficiency (194.0) has been outstanding. He's done a good job of being a disciplined player. Jim Bollman
efficiency extreme extremes fear generate market periods proper
During periods of extreme fear or greed, you don't have the proper balance between those two to generate market efficiency and you get extremes in behavior. Andrew Lo
efficiency law limit permits present promise rapidly service
To the limit the present law allows, I promise you there will be unification as rapidly as the efficiency of the service permits it. Louis A. Johnson
fuel help normal pursuing solutions
We are aggressively pursuing solutions that will help get fuel deliveries back to a more normal status, David Lemmon
fuel hard
Are you gonna fuel your faith or fuel your fear? I'm all about fueling my faith, especially when it's hard to do so. Carrie-Anne Moss
fuel increase massive seen
We have seen a massive increase in fuel prices. Martin George
fuel matter meaning producing research
We have said long before that the matter of research is not part of the negotiation, research has its own meaning and it has nothing to do with producing fuel industrially. Ali Larijani
fuel happy
We want more from the chancellor. We are not happy with the levy on fuel tax. Steve Williams
fuel talk
What they've got to do is talk about fuel efficiency. Daniel Gorrell
fuel head meeting objectives possible protecting start supply
We're getting a head start in meeting the president's objectives of protecting Americans from possible fuel supply disruptions this winter, Bill Richardson
fuel hoping instead offset passengers price raise ride
We're hoping to be able to offset the price of fuel ... by having more passengers ride ... instead of having to raise fares, Mike Rizzo
fuel understand
We know you're out there, ... We understand there's been fuel shortages. Bill White
setting work
When I work on a novel, I usually have one character and a setting in mind. Kevin Henkes
setting various
There are various interpretations of the new law. It is setting us back. Sam Aiona
setting whatever whether
She's our unquestioned leader. She does so much, whatever we need, whether it's points, rebounds, assists, setting up plays. She does it all. Mike Harris
setting unable women
In the Sixties, fashion was about liberation. It was about setting women free; it wasn't about being unable to walk. Veruschka von Lehndorff
setting
I don't think it's so much of a disadvantage setting up from scratch. David Leslie
setting
I have begun, with my colleagues, setting up a new party, Ariel Sharon
setting team win
I'd been setting up my team all night, ... I'm going to win the game. That's what I do. . . . They didn't say it was going to be easy. Gilbert Arenas
setting
We've got the possibility of setting things right, Ruby Dee
setting talking teenagers
We've got two teenagers we're talking to right now, and one of them has confessed to setting the fire. Yvonne Martinez
simple different missionary
I realized that my life was to be one of simple, childlike faith, and that my part was to trust, not to do. I was to trust in Him and He would work in me to do His good pleasure. From that time my life was different. Charles Studd
simple destiny joy
God's plan for enlarging His kingdom is so simple - one person telling another about the Savior. Yet we're busy and full of excuses. Just remember, someone's eternal destiny is at stake. The joy you'll have when you meet that person in heaven will far exceed any discomfort you felt in sharing the gospel. Charles Stanley
simple world doctrine
The anitya doctrine is, again, not quite the simple assertion that the world is impermanent, but rather that the more one grasps at the world, the more it changes. Alan Watts
simple differences panic
The difference between being an actor and a director is simple. The director has to hide his panic; the actor doesn't. Alan Rickman
simple awful
Nothing's that simple, not even things that are simply awful. Alan Moore
simple color simplicity
Keep it simple: In general, interfaces should use simple geometric forms, minimal contours, and a restricted color palette comprised primarily of less-saturated or neutral colors balanced with a few high contrast accent colors that emphasize important information. Typography should not vary widely in an interface. Alan Cooper
simple world pleasure
Nothing in or of this world measures up to the simple pleasure of experiencing the presence of God. Aiden Wilson Tozer
simple balls golden
I've often been described more than once in my life as very much like a golden retriever. Just sort of happy and excited to do whatever it is even if it's as simple as retrieving a ball and bringing it back ad nauseum. Chris Carmack
simple men games
Men do communicate, often very directly, but women sometimes cannot accept how simple what we have to say is. We seldom play games--we aren't that sophisticated. Chris Abani
strong jobs men
No two things differ more than hurry and dispatch. Hurry is the mark of a weak mind, dispatch of a strong one. A weak man in office, like a squirrel in a cage, is laboring eternally, but to no purpose, and is in constant motion without getting on a job; like a turnstile, he is in everybody's way, but stops nobody; he talks a great deal, but says very little; looks into everything but sees nothing; and has a hundred irons in the fire, but very few of them are hot, and with those few that are, he only burns his fingers. Charles Caleb Colton
strong mind haste
Hurry is the mark of a weak mind, dispatch of a strong one. Charles Caleb Colton
strong party reason
He that aspires to be the head of a party will find it more difficult to please his friends than to perplex his foes. He must often act from false reasons which are weak, because he dares not avow the true reasons which are strong. Charles Caleb Colton
strong hands monsters
The mob is a monster, with the hands of Briareus, but the head of Polyphemus,--strong to execute, but blind to perceive. Charles Caleb Colton
strong advice desire
When we feel a strong desire to thrust our advice upon others, it is usually because we suspect their weakness; but we ought rather to suspect our own. Charles Caleb Colton
strong passion may
Strong as our passions are, they may be starved into submission, and conquered without being killed. Charles Caleb Colton
strong men thinking
Men of strong minds and who think for themselves, should not be discouraged on finding occasionally that some of their best ideas have been anticipated by former writers; they will neither anathematize others nor despair themselves. They will rather go on discovering things before discovered, until they are rewarded with a land hitherto unknown, an empire indisputably their own, both right of conquest and of discovery. Charles Caleb Colton
strong circles errors
Unity of opinion is indeed a glorious and desirable thing, and its circle cannot be too strong and extended, if the centre be truth; but if the centre be error, the greater the circumference, the greater the evil. Charles Caleb Colton
strong two mind
No two things differ more than hurry and despatch. Hurry is the mark of a weak mind; despatch of a strong one. Charles Caleb Colton
successful mislead-us watches
Falsehood is never so successful as when she baits her hook with truth, and no opinions so fatally mislead us as those that are not wholly wrong, as no watches so effectively deceive the wearer as those that are sometimes right. Charles Caleb Colton
successful causes flourishing
The increasing importance of Sydney must in some measure be attributed to the flourishing condition of the colony itself, to the industry of its farmers, to the successful enterprise of its merchants, and to particular local causes. Charles Sturt
successful men errors
Complicity with error will take from the best of men the power to enter any successful protest against it. Charles Spurgeon
successful mud viruses
Why do we argue? Life's so fragile, a successful virus clinging to a speck of mud, suspended in endless nothing. Alan Moore
successful coins tossers
The probability of ten consecutive heads is 0.1 percent; thus, when you have millions of coin tossers, or investors, in the end there will be thousands of very successful practitioners of coin tossing, or stock picking. Alan Greenspan
successful stuff way
Corruption, embezzlement, fraud, these are all characteristics which exist everywhere. It is regrettably the way human nature functions, whether we like it or not. What successful economies do is keep it to a minimum. No one has ever eliminated any of that stuff. Alan Greenspan
successful thinking next
The thing I think about is that once you've done it, you then start to think about what you're going to do next. It's much easier to follow something that's not been as successful as this. Alan Bennett
successful strive do-the-best
Not everything is going to be successful. To strive for that is really naive. You just do the best you can do. Alan Ball
successful animal different
We're highly social animals - I'm told by scientists that what makes us different from other animals is an acute social awareness, which is what has made us so successful. Alan Alda
tips
We're getting hundreds of tips all over Mexico. Rich Knighten
tips
Tips for a long lifeKeep sweet, keep friendly, keep loving, if ye would keep young Edgar Cayce
tips
I don't know about that. I don't know if he can take any tips from me. We play two different sports. Lee Humphrey
using-people gay evil
One of the many evils this world has to offer is the sin of homosexuality. Satan, the enemy is using people to further his agenda to destroy the Kingdom of God and as many souls as he can. Alan Chambers
using-your-talents giving bird
Use those talents you have. You will make it. You will give joy to the world. Take this tip from nature: The woods would be a very silent place if no birds sang except those who sang best. Bernard Meltzer
using whether
I think every woman should be using a foundation, whether it's liquid or compact. Aerin Lauder
using
The only use for an atomic bomb is to keep somebody else from using one. George Wald
using
This current round of gigs, I'm just doing it using pure electronics. Tom Jenkinson
using work
When you work with chains or any kind of weapons, or just when you're using hand-to-hand combat, you are going to get hurt. Lucy Liu
using
We are using resources as if we had two planets, not one. There can be no 'plan B' because there is no 'planet B.' Ban Ki-moon
using
Basically, if I have no intention of using a service then I won't bother reverse-engineering it. Jon Johansen
using
It's interesting to play a female character who's not ever using feminine wiles to get things done. Allison Tolman