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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
attractive-things scotland people
One of the attractive things about being in Scotland is that we have a very good pipeline of new people coming into the company from the excellent universities around us. David Milne
attracted emotional films force tend
I tend not to be so attracted to films that force me into an intellectual place over an emotional one. Lisa Cholodenko
attract begin birth cloud colonies entire hundred inherit leave pass single time trillion unseen womb
We inherit every one of our genes, but we leave the womb without a single microbe. As we pass through our mother's birth canal, we begin to attract entire colonies of bacteria. By the time a child can crawl, he has been blanketed by an enormous, unseen cloud of microorganisms - a hundred trillion or more. Michael Specter
attractive catholic children himself product schools sent
The other thing that was attractive to me is that he himself is a product of Catholic schools and has sent two children through Catholic schools. Dan Garrett
attractive companies direct earnings effect interest less rates rising stocks worries
The possibility of rising interest rates worries investors. For many companies there is a direct effect on their earnings and stocks can also become less attractive to bonds. Felix Lanters
attract easily fact great kentucky league losing perception players power program teams therefore true
The perception that Kentucky is down, therefore the league is down, is very true because they are the flagship program in the SEC. It's a combination of (UK) and the fact that (success) in power conferences is cyclical. Often a league that can attract top-caliber recruits is more easily susceptible to losing great players to the NBA. How much better would some of these teams be if they had those players now? Fran Fraschilla
attracting declined seeing segment success
We are seeing a lot of success in the ski/wakeboard segment in attracting new boaters, while pontoons have declined substantially in this area. Eric Sorensen
attractive believe both broader capital commitment companies component continue corporate driven equity fill financing flexible generate growing helps junior levels markets pleased private provide providing record returns solutions sponsors street strong superior time york
We are pleased to continue our partnership with York Street Capital. This expanded capital commitment helps to fill the growing need for junior capital driven by strong buyout markets and record levels of private equity fundraising. Through York Street, we are providing broader financing alternatives to companies and equity sponsors at a time when flexible junior capital solutions are an important component in financing both buyouts and corporate expansion. We believe that York Street will continue to generate superior returns and provide attractive co-investment opportunities for Teachers' Private Capital. Jim Leech
attraction catchy guys might monday night regularly seasons three
We started three seasons ago with Monday Night Football. We thought it might be a catchy attraction to get guys who don't regularly go to church. John Snow
brain mentor able
Eloquence, to produce her full effect, should start from the head of the orator, as Pallas from the brain of Jove, completely armed and equipped. Diffidence, therefore, which is so able a mentor to the writer, would prove a dangerous counsellor for the orator. Charles Caleb Colton
brain bud taste
We have developed a culture in which we eat with our taste buds, not our brains. David H. Murdock
brain literature nuclear
The nuclear generator of brain sludge is television. Dave Barry
brain damage economics
Conventional economics is a form of brain damage. David Suzuki
brain bills lightning
Quick as lightning Wild Bill pulled his revolver. The stranger fell dead, shot through the brain. Buffalo Bill
brain may pages
Sometimes I get a lyric, and the lyric, you know, comes off the page, and goes into my brain and comes out with a melody. Other times, I may create a melody first. Carole King
brain information too-much
Too much information will make your brain choke. Bryan Davis
brain despair strikes
Despair doth strike as deep a furrow in the brain as mischief or remorse. Bryan Procter
brain
Close up your head; your brain is getting loose. Catherynne M. Valente
challenges want musician
I always want to set myself a challenge by doing something no-one would expect me to do! But, having said that, I don't feel as a musician you can steer too far away from what you normally do. Akon
challenges refuse solutions
We are a nation that seeks out solutions and refuses to ignore challenges. Chris Chocola
challenges way lucky
I love any challenge that comes my way, and I've been lucky to have many. Chris Bauer
challenges gone television
The scripts for Marco Polo are absolutely, positively fantastic. The challenge of making that show in China has proved to be as formidable as we feared. It's not like making a movie in China where, once you load up and you leave, you're gone. We have to be able to come back and capture something that's going to feel like a major feature film, on a television budget, and do it, hopefully season after season, so we are taking more time than the producers thought. Chris Albrecht
challenges
I have always loved a challenge. Chita Rivera
challenges sophisticated feels
I feel that audiences are very sophisticated, and part of my challenge is to keep them engaged because they are so complex. Chiwetel Ejiofor
challenges traps ifs
A trap is only a trap if you don't know about it. If you know about it, it's a challenge. China Mieville
challenges trying growing
I like to challenge myself. I like to learn - so I like to try new things and try to keep growing. David Schwimmer
challenges acting telling-stories
I love telling stories. I like the challenges presented to me on a daily basis. There's nothing resting about acting. David Morrissey
conditions environment family
We are fashioned not by our genes, but by our environment - by the family and socio-historic conditions in which we evolve. Michel Onfray
conditions monetary strength
The pound's strength is tightening monetary conditions in the U.K., but it's not enough. Stewart Newnham
conditions consumer continue high improvement labor spending support wage
The possibility is high that an improvement in labor and wage conditions will continue to support consumer spending going forward. Taro Saito
conditions saw seeing similar
We are seeing conditions that are similar to about what we saw in 2002. William Paul
conditions diseases infectious preparing spread
We are preparing for the possibility of infectious diseases that could be spread under conditions of crowding in shelters, Julie Gerberding
conditions looking martha violated whether
We are looking into whether Martha Stewart violated the conditions of her release, Chris Stanton
conditions country create divided government
There are conditions to create a government and to govern, even if the country is divided in two. Piero Fassino
conditions four handle three
There are some conditions we just can't handle here. Like dialysis. We can't do that, and they'll be here three or four days, so they'll need it before then. Kevin Stephens
conditions cope flourishes virtue
Where there are difficulties to cope with, and unsatisfactory conditions to overcome, there virtue most flourishes and manifests its glory. James Allen
draining fighting sports time waste
Fighting is a very emotionally draining sport. I don't want to waste time on drama beforehand. Holly Holm
draining great lights offices proud york
One of the things you see in New York is that offices keep their lights on at night. They're proud of their building. Great. But they must find another way to be proud without draining energy. Richard Rogers
drains contact offers
Anyone we come in contact with, we either offer them life, or we drain them. Brennan Manning
drains feels
It is an appalling thing to feel all one possesses drain away. Blaise Pascal
draining energy helping innings modest neither nor
Modest innings were draining him. He had no energy to give to the team, which was helping neither him nor us. Greg Chappell
draining foundation others replaced roof save sides three
We've shored up the foundation and addressed the moisture problem. The tile roof was all removed, and we were able to save three sides and replaced the others with duplicates. It wasn't draining properly. Holly Hawkins
drain entire explain face fixed funding level people social ultimately undermine
We must level with the people and explain to them that Social Security will first face funding problems in 2042 that can be fixed now with changes that do not undermine and ultimately drain from the entire program. Grace Napolitano
drain guys momentum power rolling
When you're on the power play you get the momentum rolling for you, even when you don't score. You drain the guys who are killing penalties. Ian Laperriere
drained order ourselves time
As caretakers, we feel drained when caring for another, and in order to take care of someone else, we need to take care of ourselves at the same time. Jenna Morasca
educational keys doors
A very little key will open a very heavy door. Charles Dickens
education teaching brain
Pedantry crams our heads with learned lumber and takes out our brains to make room for it. Charles Caleb Colton
education book men
He who studies books alone will know how things ought to be, and he who studies men will know how they are. Charles Caleb Colton
education mind armor
The acquirements of science maybe termed the armor of the mind. Charles Caleb Colton
education teaching knowledge
Examinations are formidable even to the best prepared, for the greatest fool may ask more than the wisest man can answer. Charles Caleb Colton
education prayer men
An unschooled man who knows how to meditate upon the Lord has learned far more than the man with the highest education who does not know how to meditate. Charles Stanley
educational clothes giving
Our educational system in its entirety does nothing to give us any kind of material competence. In other words, we don't learn how to cook, how to make clothes, how to build houses, how to make love, or to do any of the absolutely fundamental things of life. Alan Watts
education learning buddhism
A scholar tries to learn something everyday; a student of Buddhism tries to unlearn something daily. Alan Watts
education country government
The United States government has the obligation to educate all young people in this country. Al Sharpton
faculty four himself lose man
It must be that a man who shuts himself up between four walls must lose the faculty of associating ideas and words. Jules Verne
faculty great priorities private recruit retain support
One of the priorities of ?Campaign Arizona' was endowed support of faculty and staff, not only to retain the great faculty that you already have but also to recruit more from other institutions or private industry. Rodney Campbell
faculty great learn students writer
Now, students and faculty can all learn about this great writer firsthand, Frank Turner
faculty future golf great holes hope moment offer proud provide rates staff student students university walk week
We're proud that any student can walk and play 18 holes of golf for $5 during the week and $8 during the weekend. Faculty and staff will have discounted rates as well. It's a great thing for the university as a whole. Students will have to provide their own equipment. In the future we hope to offer rental sets, but at the moment we don't have any. Rich Ballinger
faculty people quality students super support teachers thank work
I thank the faculty and administration and students for their support over the years. We have super teachers who are quality people to work with. Ben Borries
faculty good leader quiet shows
He is a quiet leader and an outstanding student. What impresses me the most is that all of the faculty have nothing but good things to say about him, and that shows his character. Gene Pingatore
faculty missed presence professor
The PPL faculty have also missed Professor Arthur's presence and participation in the department. Steven Scalet
faculty group meetings personal small textbook
We are encouraging personal meetings and small group discussions between faculty and the textbook representatives at every opportunity. Virginia Johnson
faculty focus issues members people races tend
Faculty members tend to focus on those issues just like people of all races tend to do. Keith Jackson
feature
Feature filmmaking is a different kind of complication as documentary comes in the editing room. Nicholas Jarecki
feature whether
Whether it would be a feature film or not I didn't know. Michael Almereyda
feature guy moved receiver
When we began, we had him at receiver and I didn't have a guy who could tote the mail. When we moved him to tailback, I told him I was going to feature him. Rod Oden
feature felt good hit hole instead move running
We felt like we had a good corral of running backs, so instead of running the (I-formation) and featuring one, we wanted to feature more backs. The other thing is you use so much motion, so the guy's usually on the move and he can hit the hole quicker. Dave Adams
feature life might modern oppose sad
However, we might oppose it, abortion is a sad feature of modern life. Robert Casey
feature mind
We did this film in 13 days, mind you. And 13 days is not very long for a feature film. Nobody in their right mind would argue that. Nobody in their right mind would do that. Kurtwood Smith
feature grew high prime school shows time tv
We have a lot of American TV in Australia. I grew up watching 'Seinfeld,' 'The Simpsons' and those prime time TV shows over the years that feature grown-ups and high school kids. We had a saturation of American voices. Sarah Snook
feature novels people
People who actually tell stories, meaning people who write novels and make feature films, don't see themselves as storytellers. Stefan Sagmeister
feature industry island journalist premier production solid television tourist travel
The production of the television feature by the renowned travel journalist was a solid endorsement of Jamaica's tourist industry and an affirmation of the island as a premier destination, Paul Pennicook
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
higher rising students
We have to get students rising to that higher standard. John Winn
higher naturally raise software stocks trade
We're going to see more software acquisitions at higher valuations. Stocks naturally will trade higher when you raise the bar. Patrick Mason
higher law past quality submit
We are getting more submissions so, on the law of averages, we are going to end up with higher quality bands. Those who didn't submit in the past now know this isn't some rinky-dink festival. Bill Donabedian
higher prices
Ultimately, it will be higher prices for the consumer. Charles Holliday
higher life people
In centenarians and supercentenarians - people over 110 - you see a higher level of fecundity much later in life. S. Jay Olshansky
higher
Nobody is going to occupy a place higher than I. Alexis de Tocqueville
higher percentage trying
We're just trying to get better down there, ... We just need to get more (touchdowns). We're not going to get a touchdown every time, but we need to get a higher percentage of them. Mark Richt
parts people please simply teachers
I see a lot of actors that are doing things to please their coaches, their teachers in the past. They say 'No' to parts they should have said 'Yes' to simply because of the opinion of people in their past. I have no one in my past who is judging me and saying, 'Maybe you shouldn't do that.' I'll do it all. Terry Crews
parts truck
We're an International truck dealer, sales, parts and service. Ken Thompson
parts worth
LCS and Communicator are not worth a whole lot without the back end. They have to have the back end in place, or the other parts don't move. Rob Enderle
parts
We don't know what parts are going to be implemented or how we are going to do it yet. Tela Mange
parts
I don't think, as an actress, you want to be beautiful. It's actually a disadvantage because that's not where all the interesting parts lie. Tuppence Middleton
parts strongest
One of the strongest parts to our organization is depth. It allows us to do a lot of things. Bill Stoneman
parts wherever
You can go to Europe, and there's no turnin' back - any parts of Europe. Wherever you are, there is no stop and go for the blues. The blues go but it don't stop. John Lee Hooker
parts people point replace rid shoot willing
I don't think we're at the point where most people are willing to get rid of body parts and replace them, but then again, people who shoot lasers in their eyes come out with better-than-perfect vision. John Scalzi
parts society takes
I don't think it takes much for a cult to be a cult. Many parts of our society are cultish, and you only need a charismatic leader and some teachings, and before you know it, you have a cult. Jerome Flynn
poor
Suffice it to say, I'm not poor. August Wilson
poor backgrounds harder
If you're from a poor background, you have to work even harder. But that's what makes you who you are. Carol Vorderman
poorly pressure stage
We were awful, we started poorly and never got in the game. At no stage did we put any pressure on the French. Andy Robinson
poor starters finishers
I hired finishers because I'm a good starter and a poor finisher. Alan Kay
poor
What have they done to you, my poor child? Johann Wolfgang von Goethe
poor-richard reproach
The Sting of a reproach, is the Truth of it. Benjamin Franklin
poor
It is a poor thing for the writer to take on that which he doesn't understand. Anton Chekhov
poor sad tired
Too tired to yawn, too tired to sleep: / Poor tired Tim! It's sad for him. Walter Mare
poor poverty-and-the-poor
The poor would never be able to live at all if it were not for the poor. George Moore
problem chopping horns
...the habitual dualist's solution to the problem of dualism: to solve the dilemma by chopping off one of the horns. Alan Watts
problem holy judaism
We have no problems with Jews and highly respect Judaism as a holy religion. Akbar Hashemi Rafsanjani
problem thousand right-place
As God is exalted to the right place in our lives, a thousand problems are solved all at once. Aiden Wilson Tozer
problem theological handiwork
Because we are the handiwork of God, it follows that all our problems and their solutions are theological. Aiden Wilson Tozer
problem bigs big-problems
The big problem is not whether the Bible is true. The big problem is whether it is true in you. Aiden Wilson Tozer
problem sort
We want to sort of put this out there that this is an institutional problem and not just one incident. Justin Davis
problem wells solutions
If you can properly define the problem, then you've already defined the solution as well. Chip Kidd
problem gender should
The problem with gender is that it prescribes how we should be, rather than recognising how we are. Chimamanda Ngozi Adichie
problem victim
Those who fume at their problems become their victims. David Seabury
striking time tough
Legislators are going to have a tough time striking that balance. Larry Morandi
striking
I'm striking out way too much. I'm not making any adjustments, either. Chris Shelton
striking
It's like striking out in baseball. It's a long way back to the bench. Scott Gomez