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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
among french
There would probably be less of a frenzy among the French public. Michel Patini
among societies
Societies should be judged by how they treat the weakest among them. Maajid Nawaz
among efforts parents people possible rates remain though
The possible slowdown of illicit drug use among young people is encouraging, even though rates of use remain unacceptably high. All of us, especially parents and teachers, need to redouble our efforts Donna Shalala
among aware changed difficult game golf good grown hard high number people perception players respect school
The perception of high school golf a number of years back was not the highest, that it wasn't that hard a sport. That has all changed as the game has grown - especially among young people. There is a lot more respect for the players and the sport. People now are aware of how difficult it is to be good at golf. Bob Hamilton
among computing game held high jobs parents perception school students widely
The perception among high school students and their parents is that the game is over, that all computing jobs are going overseas. It's an extraordinarily widely held misperception. David Patterson
among apt businesses carry climate economic economy employees executives focus global growth hiring hopeful improving indicator might optimism perception postponed programs spending stronger top
The perception among C-suite executives that the global economy is getting stronger should be a hopeful indicator for global business. As optimism for the global economic climate improves, top executives are more apt to focus on improving their own businesses by spending for programs that might have been curtailed or postponed and by hiring new employees to carry out their growth plans. Mark Foster
among customers direct microsoft nobody perception products relationship security
The perception among a lot of customers is that nobody understands Microsoft products like Microsoft. Many of them want the security of that direct relationship with Microsoft. Dwight Davis
among human impossible point
The point of 'Othello,' among other points, is that it is impossible to know another human being, Patrick Page
among competition forward looking owns vibrant
We are looking forward to a vibrant competition among politicians for these voters. No one owns them. Gary Bauer
capable pitcher ride step
The other two (pitchers) will come around because we can't ride one pitcher the whole season. They have to step up, and they're capable of doing that. JoAnne Graf
capable knocking
(The other riders) were all stressing. As long as they know (I'm capable of knocking them off), that's all that matters. Bucky Lasek
capable million shown tests
We've already shown in tests that we're capable of doing 1 million gallons a day. Rich Henning
capable given goals good hope last possibly result run team victories winning
We are a team that always has goals in it and as a result we are capable of winning anywhere. It will need a good run from us, possibly half-a-dozen victories from our last 11 games, but we haven't given up hope yet. Terry Harris
capable dangerous five good overlook positions season teams winning
There are some good teams in this sectional, so I don't think you can overlook anyone, ... From our standpoint, we thought when the season started that we could be dangerous at all five positions and we think we have been. We think we're capable of winning it all -- there's a chance. Mike Wise
capable games playing
We still need someone else who is capable of playing 20 to 25 games a year. Don Waddell
capable directors great saying taking themselves
I think today there are too many directors taking themselves seriously; the only one capable of saying anything really new and interesting is Luis Bunuel. He's a very great director. Luchino Visconti
capable example good wayne work
Wayne McGregor's 'Dyad 1929' is a good example of this capable British choreographer's work. Robert Gottlieb
capable certainly energy high hurt level memphis playing points putting
When he got hurt in Memphis he was playing at a high level in the first half. We need him. We need him out there. We need his energy and certainly we need the way he?s capable of putting points on the board. Maurice Cheeks
civilized example expect message send society strong
We want to send a very strong message ... this is not what we expect out of civilized society, ... We're going to make an example of somebody. John Wilson
civilized greater importance relatively verb
The verb is relatively of much greater importance in an Indian tongue than in a civilized language. John Wesley Powell
civilized ensure independence
There is a requirement to ensure the withdrawal takes place in a civilized manner. We will be able to show the world we deserve independence and freedom. Mahmoud Abbas
civilized societies
Free and civilized societies do not hold prisoners incommunicado. Tom McClintock
civilized goes left running
When your whole system, your whole civilized system goes down, this is pretty much what you get left with. We have no communications, no running water, no electricity, no real help. Kathleen Blanco
civilized freedoms protect rest
to protect the freedoms of the rest of the civilized world. Hoshyar Zebari
civilized measure redemption society
Redemption is possible, and it is the measure of a civilized society. Greg Boyle
civilized corps nations recoil
On the day when two army corps may mutually annihilate each other in a second, probably all civilized nations will recoil with horror and disband their troops. Alfred Nobel
civilized
The Internet does not have a reputation as being a particularly civilized place. Anita Borg
conditions environment family
We are fashioned not by our genes, but by our environment - by the family and socio-historic conditions in which we evolve. Michel Onfray
conditions monetary strength
The pound's strength is tightening monetary conditions in the U.K., but it's not enough. Stewart Newnham
conditions consumer continue high improvement labor spending support wage
The possibility is high that an improvement in labor and wage conditions will continue to support consumer spending going forward. Taro Saito
condition cultural personal spread travel-and-tourism
The personal appropriation of clichTs is a condition for the spread of cultural tourism. Serge Daney
conditions saw seeing similar
We are seeing conditions that are similar to about what we saw in 2002. William Paul
conditions diseases infectious preparing spread
We are preparing for the possibility of infectious diseases that could be spread under conditions of crowding in shelters, Julie Gerberding
conditions looking martha violated whether
We are looking into whether Martha Stewart violated the conditions of her release, Chris Stanton
conditions country create divided government
There are conditions to create a government and to govern, even if the country is divided in two. Piero Fassino
conditions four handle three
There are some conditions we just can't handle here. Like dialysis. We can't do that, and they'll be here three or four days, so they'll need it before then. Kevin Stephens
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
few-words speak adages
With few words, one can speak the truth. Bryan Adams
fewer
Much better to do fewer things and have time to make the most of them. Carl Honore
few liked love properly sure
I don't think I've ever properly been in love. I've had a few girlfriends and have liked them loads, but I'm not sure it was love. Luke Pasqualino
few helping hit move next plugging series work
Those three years on 'Loving' were instrumental in helping me move through the next few years of work, where it was hit or miss. I was on series that would get canceled, then I would be a movie that wouldn't come out or do as well as I hoped. You learn that you have to just keep plugging away and never take anything for granted. Michael Weatherly
few gave intrigued khan money next politics registered sure titles typical
I have registered few titles like 'Bharat Bandh,' 'Calendar Girl,' 'Money Politics.' The titles just intrigued me, so I registered. I had a title, 'Jai Ho,' which I gave to Sohail Khan for his next film with Salman Khan. These are typical Madhur Bhandarkar kind of films. I may make a film or not on such titles... not sure yet. Madhur Bhandarkar
few matter mean minutes stopped
We stopped doing what we were doing and we let them right back in the game. Then we're tied. No matter what we did in the first few minutes it didn't mean anything. Tim DeBruycker
few learning players season
We started off the season making a few more turnovers than we would have liked, but a lot of that had to do with all the new players learning a new system. Joddie Gleason
few missed picked receive serve serves
We started a little slow, and we picked it up after the first loss. We didn't serve receive well, and we missed a few serves that were critical. That just comes with experience. Nancy Diers
few games needed played playoff stay
We started a few games where we started strong, experience-wise but we should have played better in the end. We needed this game to stay in the playoff hunt. Jamie Watson
forming government proceed
We want the negotiations on forming a new government to proceed quickly. Matthias Platzeck
forming results talk time whenever
Whenever the results of the investigation come to the surface, then the time will be suitable to talk about forming the new government. Ayad Allawi
forming people
We're just forming this on our own. We're just going to give people another voice. Steve Kolenda
forming guiding needs strategies yardstick
To get the most from agricultural resources, poor farmers' needs must come first, guiding investment strategies and forming the yardstick for gauging results. Sylvia Mathews Burwell
forming neural throughout
Our brains have the ability to reorganize themselves by forming new neural connections throughout our lives. This ability is called neuroplasticity. Elizabeth Thornton
forming marketing niche push step
This would be another step for Boone in biotech and value-added agriculture to push that marketing niche we're forming in our community. Brent Trout
forming involved willing
We are more than willing to get involved in forming a new system. Rob Reiner
forming interest means nobody none sold somebody special tied
Nobody is tied to a special interest, none that I can discern, which means they are all independent, and that is so important to forming a team, because if you have somebody who is sold out to a special interest they're never going to get along. Phil Hardberger
forming name
I think a lot of it is a forming of attitudes. I think, primarily, they know our name but they don't know much about us. John Newton
fortune difficulty careful
That which we acquire with the most difficulty we retain the longest; as those who have earned a fortune are usually more careful of it than those who have inherited one. Charles Caleb Colton
fortune nations accidents
The fortune of nations has often depended on accidents . . . Edward Gibbon
fortune good-fortune
I had the good fortune of having a happy, closely knit family. Carlos Fuentes
fortune-cookie plans
It's better to have a bad plan then no plan at all. Charles de Gaulle
fortune tricks
Fortune has played me a sad trick by letting me live on and on. Belle Boyd
fortune good imposed privilege rank
The responsibilities which are imposed by rank and privilege and good fortune can... become very onerous indeed. Robert W. Welch, Jr.
fortune good ray
Luckily, I have the good fortune of being on the same team as Ray Lewis. I don't have to face him on Sunday. Jamal Lewis
fortune found gotten hanging meeting particular special
I've had the fortune of meeting most of the 'Kids in the Hall.' One meeting was special in particular because this was before I had gotten anything, before anything was clicking, and I just found myself hanging out with Scott Thompson. Thomas Middleditch
fortune hostage
Every happiness is a hostage to fortune. Arthur Helps
good-morning beauty nature
Nature gives to every time and season some beauties of its own; and from morning to night, as from the cradle to the grave, it is but a succession of changes so gentle and easy that we can scarcely mark their progress. Charles Dickens
good-friend trying disability
Try not to associate bodily defect with mental, my good friend, except for a solid reason Charles Dickens
good-life two evil
Of two evils, it is perhaps less injurious to society, that good doctrine should be accompanied by a bad life, than that a good life should lend its support to a bad doctrine. Charles Caleb Colton
good-things cruelty
A good thing can't be cruel. Charles Dickens
good-man energy attention
Promptitude is not only a duty, but is also a part of good manners; it is favorable to fortune, reputation, influence, and usefulness; a little attention and energy will form the habit, so as to make it easy and delightful. Charles Simmons
good-day writing emotional
If you give me a typewriter and I'm having a good day, I can write a scene that will astonish its readers. That will perhaps make them laugh, perhaps make them cry - that will have some emotional clout to it. It doesn't cost much to do that. Alan Moore
goodbye farewell heart
The best things said come last. People will talk for hours saying nothing much and then linger at the door with words that come with a rush from the heart. Alan Alda
good-movie complicated enjoyable
A truly good movie is enjoyable too. There’s nothing complicated about it. Akira Kurosawa
good looking
We want them all to go on, and realistically they all have a shot. They all want to be state-placers and they're all looking to be pretty tough. I just want them all to have a good time. Brian Nicola
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
high junior played president schools york
I was president of the schools in junior high and high school, got a scholarship to New York University, played a little basketball, and was a celebrity. Louis Gossett, Jr.
highly regarding requests side
The other side has not responded to any of our requests regarding the abduction issue, so it is highly regrettable. Shinzo Abe
high potential profits
The potential profits are so high there's a win-at-any-cost mentality. James Browning
high models perception prices support
The perception is that it's too high end, too futuristic, but I think we will see prices and use models to support it. Mark Thompson
highest income leave north pay people simply tax
The people who pay the highest income tax are also the most mobile. They simply leave North Carolina. John Connaughton
high trying unique yorkers
We are always trying to look for unique ideas, and we wanted something new for New York. We thought that hey, it's an island, let's do something on the water...New Yorkers have pretty high expectations. John Remington
high large previous risk state
We've always been on a high state of alert. The perpetrators of the previous bombings are still very much at large and the risk is still very much with us, Marty Natalegawa
indeed success
Were I to flatter myself with the possibility of success in such combat, it would indeed be presumption. Anna Seward
indeed women
I'm indeed a mandasi seller, and I'm proud of it, because the majority of women in Malawi are like us, mandasi sellers. Joyce Banda
indeed mind ways
It is a damn poor mind indeed which can't think of at least two ways to spell any word. Andrew Jackson
indeed software wide
There is indeed such a bottleneck, and if their software does what they claim, it should get wide support. Bob Wheeler
indeed life number whatever
Whatever the number of a man's friends, there will be times in his life when he has one too few; but if he has only one enemy, he is lucky indeed if he has not one too many. Edward G. Bulwer-Lytton
indeed less poetry rather rhetoric sensuous subtle
Rhetoric . . . To which poetry would be made subsequent, or indeed rather precedent, as being less subtle and fine, but more simple, sensuous and passionate. John Milton
indeed security
But as to how many they are, we don?t really know and they are indeed a security concern. Michael Defensor
indeed mean privilege
I am indeed completely nuts, but that doesn't mean I don't care about how I look. Sometimes, I admit, I will privilege appearance over comfort. Russell Smith
indeed needs shared
His story is indeed a story that needs to come out, and needs to be shared with the world. Shakeel Syed
moral courageous obligation
I feel that it is our moral obligation to stand and to be courageous with these families, and particularly Cindy, that have become the conscience of this nation. Al Sharpton
moral manners pleasure
To offend is my pleasure; I love to be hated. Edmond Rostand
morality
Morality is but the vestibule of religion. Edwin Hubbel Chapin
moral compromise
It is a moral issue how we are going to treat workers. On these issues, these are moral issues, principled issues, where there aren't compromises. Edward Kennedy
moral-corruption indifference crime
The accomplice to the crime of corruption is frequently our own indifference. Bess Myerson
moral sock behave
It was time to pull my moral socks up and behave myself. Charlaine Harris
moral conformity resolve
All moral obligation resolves itself into the obligation of conformity to the will of God. Charles Hodge
morality credibility knows
Do you know why I have credibility? Because I don't exude morality. Bob Hawke
moral reluctance seems
We seem to be afflicted by a widespread and eroding reluctance to take any stand on any values, moral, behavioral or esthetic. Barbara Tuchman
none useless vain
Where none admire, 'tis useless to excel; / Where none are beaux, 'tis vain to be a belle. Lord Lyttelton
none tread
When we are young we long to tread a way none have trod before William Butler Yeats
none partners stressful sure
We're going to make sure none of his partners put him in any kind of stressful situation. Kenny Perry
none partners stressful sure
We're just going to make sure none of his partners put him in any kind of stressful situation. Kenny Perry
none stories
I can think of no one that my grandparents knew, that told me stories and that I experienced myself, had any sense of social inferiority growing up in segregated Washington. None whatsoever. Ed Smith
none proposed site
Site Q was proposed to be in one place, then in another place. There were all these candidates, but none of them really panned out. Marcello Canuto
none talking walking
She is talking some of the talk, but walking none of the walk. Don Brash
none
I'll answer to none but the King himself. Thomas Blood
none york
New York - that unnatural city where every one is an exile, none more so than the American. Charlotte Perkins Gilman
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
states secretary
I loved what I did. I could've been secretary of state for ever. Madeleine Albright
states evident secretary
I loved being Secretary of State, that's probably evident to everyone who watched me. Madeleine Albright
states barometer interest
...interest is the barometer of the state... David Hume
states hyperbole constant
I live in a constant state of hyperbole. Eden Sher
states senators productive
I was very productive as a senator for my state. Carol Moseley Braun
state
We wrestled better than we did in the first. We got after the guys, and they wanted to get to the state final. Clifford Garnto
state
to play in the state in which they're franchised. Paul Tagliabue
state
We're realists. We know we're in a state where the Legislature is anti-choice. Susan Hill
state systems whether
When the state inspectors look at us, they will see that the systems are in place. You have to have a system whether you have one person or 100. Al Mollozzi