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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
basically serve state
We want to serve our state and our country, that's basically it. Clifford Jordan
basically felt kansas production time took town worked
I was in Kansas for about a month, and we worked most of the time in a very small town, so it felt like the production basically took the whole town over. In a way, we were the Martians in Kansas. Lukas Haas
basically beat efficient fully markets might trained
I'm from Berkeley, California, so I'm fully trained in socialism and all, but basically what they teach you there is markets are efficient and we can't beat them, so we might as well index. Louis Navellier
basically certainly changes life relationships
'The Cardturner,' while it has bridge in it, you certainly don't need to know how to play bridge to read it. It's basically a book about relationships - between Alton and his great-uncle, and Alton and his friends, and how it changes his life. Louis Sachar
basically came played team
The other team played better than us today. That's basically what it came down to. Jim Myers
basically crowd energy felt half knew people positive received
The positive energy I received from the crowd was awesome. I felt like I basically knew half of the people in the gallery. Michelle Wie
basic cant equipment hand hear issues jobs logistics means needs offices personnel realize soldiers support
The personnel in the support offices know they are doing their jobs well when they never hear about themselves, because that means Soldiers have their food, equipment and issues squared away, ... If you look at the basic needs of Soldiersfood, shelter, a means to survivethen you realize that a Soldier cant eat, communicate, or have the equipment they need to do their job without logistics having a hand in the operation. Andy Watson
basically example football large lead plate players position rally taken team
The personality of the quarterback, he has a large plate and he is going to lead by example and by his play. That's basically where our football team is. Our players do rally around Eli and his play and that's the position he has taken and that's the way it should be. Tom Coughlin
basic hold lebanon perception rule strangle tried unable violated
the perception in the world was that they tried to strangle us. In Lebanon we violated this basic rule and we were unable to hold what we took. Ehud Barak
boot instant trade
We started bucking it, and it was an instant success. It tore up every boot in the trade show. Sam Reeves
bootleg designs versace
Versace designs have always been bootlegged. Now it's Versace bootlegging the bootleg for the bootleggers to bootleg the bootleg. M.I.A.
boots there-comes-a-time rhetoric
There comes a time when what is needed is not just rhetoric, but boots on the ground. Baldwin Spencer
booth dedicate name
We're going to dedicate the booth to him and name it after him, David Isay
boots christmas cowboy man shotgun
As a very young man growing up in Texas, usually I got a shotgun or cowboy boots for Christmas. Robert Wilson
booth life mary matter open telephone
Life with Mary was like being in a telephone booth with an open umbrella-no matter which way you turned, you got it in the eye. Jean Kerr
boots concrete fishes frank organized print rumors sleeping ties
The rumors of Frank Sinatra's violence and his ties to organized crime were such that journalists joked in print about me ending up in concrete boots and sleeping with the fishes if I proceeded to write his biography. Kitty Kelley
boots sexier stuff wears women
She's like, 'I'll do the thigh-high boots pregnant.' She wears the same kind of stuff she did before. I think women are sexier when they're pregnant, so why not go for it? Michael Kors
boot damage early except far flowering freeze growth hard heading injured late northwest occurred severe stages time wheat
Most of the wheat, except that in far northwest Kansas, was in the early boot to heading stages of growth at the time of the freezes. Damage can be especially severe if the freeze occurred in the late boot to flowering stages, but wheat can also be injured by a hard freeze at other growth stages. Jim Shroyer
campaign donations since
Unsolicited donations have doubled since the campaign started. Pam Brown
campaign citizens guidance healthier join national offer opportunity pleased provides senior simple steps toward
We are pleased to offer senior citizens the opportunity to join a national campaign that provides guidance and simple steps toward healthier lifestyles, Terry Murphy
campus dog few guide hit last
We've actually had someone on campus have their guide dog hit a few times last year. The dog now has messed-up hips. Sam Marks
campus expresses interested involved students voice
We're interested in doing something that expresses what the students on campus have to say. Those of us involved right now, we're not interested in doing a watered-down publication that is not a voice of the students. Ben Digman
campaign help possible stand worst
We stand by the report. The eviction campaign was the worst possible thing at the worst possible moment. ... The important thing now is to look to the future. We have to help these people. Jan Egeland
campaign medicare preserving programs social spoke
We spoke in this campaign about preserving social programs and Medicare and that we will do, Jean Chretien
camping cars catch dozens driving glimpse nights saw spent trying
We spent two nights camping there, but never saw anything but dozens of cars driving in at night trying to catch a glimpse of the ghost, Chad Lewis
campus grants help loans pay
Where there is a will, there is a way. There are scholarships, grants and loans that can help you pay for school; if you still need assistance, there is always campus work-study. Jenny Smith
campaign talk
We're not going to talk about campaign tactics, Mike DeWine
entertainment provocative entertaining
I'm part of what I consider the entertainment industry. For my photos to be entertaining, they have to be provocative and new. David LaChapelle
entering lives personal potential
The potential for their personal lives entering in their professional lives is dynamic. David Boreanaz
entered next thursday
The plea that will be entered next Thursday will be 'not guilty'. Andrew Patel
entertainment funniest home ourselves providing stage videos
We are providing a stage where everyone can participate and everyone can be seen. We see ourselves as a combination of America's Funniest Home Videos and Entertainment Tonight. E. Hurley
entertainment interested people providing types
We're interested in providing something for people of all types and ages. It's going to be family-friendly, and there'll be entertainment between each inning. Mike deMaine
entertainment bland entertainment-business
Generally the whole entertainment business now is bland. Eartha Kitt
entertainers havens
I haven't traditionally been a family entertainer. David Walliams
entertainment television associates
I've actually gotten so I don't associate television with entertainment very much. Dick Cavett
entering splinters becoming
Homosexuals are entering the mainstream, because they're becoming as boring and as tedious as any other splinter group. Dennis Miller
following ifs
If you'd been where I'd been... if you'd seen the things I'd seen!... you... you'd be me... Or someone following me around... Alan Parker
following gets highs looking months september whether
We want to see whether or not the following months follow on up out of here after September gets out of the way. We could be looking at the highs right now. Frank Lesh
following fun george good teams
We've all had fun following George Mason. But we've got a lot of other good teams in our league. Blaine Taylor
following house wants
A dog doesn't care if you're tired or it's raining. It wants to go out - and if it doesn't go out, it's going to be mournfully following you around the house for the whole evening. Mark Barrowcliffe
following
Dedicating myself to actually following through was my single biggest achievement. Nick Woodman
following-christ ifs mislead
If we are leading but not closely following Christ, we are misleading. Beth Moore
following guys monday players providence week
When we were 1-2 after the Providence game, our players that following week re-dedicated themselves, ... You don't get better on Friday, you get better on Monday through Thursday, and that's what these guys have done. The Vikings
following rest until
We're following up leads. We're not going to rest until we find the person responsible for this. Sheriff White
following markets oil worries
We're following international markets and their worries about the oil price. Tomas Taterka
given no-hope pledge
God has given no pledge which He will not redeem, and encouraged no hope which He will not fulfill. Charles Spurgeon
given guy guys perception
The perception now is that (Woods) is still the guy to beat. But I don't think guys think it's a given that he's going to win. Lee Janzen
given park rules
We've already given them an extension. It's really simple: The rules of the park have to be followed. Sharon Stewart
given life lived name people talk tony
I hate it when people talk about Tony Curtis and say: 'His real name was Bernie Schwartz... ' That was just the name that he was given at birth. It's not the person he lived his life with, and became. Nicolas Roeg
given movies sad
A lot of my movies have come to be thought about only years after the fact, and I'm sad about that but also happy about it in a way, as it's given them longevity. Nicolas Roeg
given relevant considering
I have given up considering happiness as relevant. Edward Gorey
given hoard wealth
Wealth that you hoard is not yours; wealth that you have given is really yours. Sathya Baba
given heck love sharks shocked
What the Sharks did, it shocked the heck out of me. We've always been rivals, but I think they know how much I love this game, and how much I've given to it. Luc Robitaille
given
We have assumed control where once we worked with what we were given. Bill McKibben
helping-someone achievement saving
Helping someone come to a saving knowledge of Christ is the greatest achievement possible. Charles Stanley
helping conservation protect
The more you know about a species, the more you understand about how better to help protect them. Alan Clark
help understand
We want them to understand we're here to help and do everything we can, Mike Harris
help organize
We want to see how we can help organize the transfer. Javier Solana
helping-others names way
Helping others is a question of being genuine and projecting that genuineness to others. This way of being doesn't have to have a title or a name particularly. It is just being ultimately decent. Chogyam Trungpa
helping conspiracy crime
Prosecutors tend to love conspiracy charges because the rules of evidence are easier, meaning you can get more in to help prove a crime. David Shuster
helping-someone stories sometimes
I love helping someone else tell their story, but I like being the storyteller sometimes. David Schwimmer
helping ability
All of those measures of relationships that you have in your life help feed your and inform your ability to act. David Koechner
helping help-me help-yourself
Seriously? You won’t help me?” “Help yourself get killed? No, I won’t. Dave Barry
intensive night searching
We've all been up all night searching for these folks. We have a very intensive search going on, Mike Haley
intensive
The patient is in intensive care but still alive. Javier Perez de Cuellar
intensive
We were able to play pretty intensive defense. Scott Rapson
intensive late next treatment undergo
He will undergo intensive treatment and will be reassessed late next week. Errol Alcott
intensive round
There will be intensive consultations in this round of the six-party talks, Song Min
intensive mastered skill technical thus
We hypothesized that cardiac auscultation is more of a technical skill and thus could be mastered through the use of intensive repetition. Michael Barrett
intensive manage review structured
We are undertaking an intensive review of how we are structured and how we manage each of our businesses. William Carpenter
intensive jobs lost outsource skilled takes workers
The jobs of 2,500 skilled maintenance workers would be lost if Qantas takes this step. The work that Qantas is threatening to outsource is the most intensive and most important maintenance work. Doug Cameron
intensive move realized room surgery time
After surgery and my time in intensive care, I was deposited in my room and I realized I was without back pain, but that I couldn't move my legs. Marie Windsor
prepared zimbabwe
We are prepared to play Zimbabwe in March. Samir Inamdar
prepared
We are prepared to go all-Boeing or all-Airbus, James Hogan
prepared
We are prepared financially to see this thing through to the very end. Brian Bogosian
prepared time
We're going to take our time and be careful. We are prepared for problems. Bob Castle
prepared
We are prepared for some things, and we receive just as fast as we prepare ourselves. Brigham Young
prepare time track work
I usually prepare a track and then I work with the artist when it's time to do the vocals. Kenneth Edmonds
prepared rubber stamp work
I am ready and prepared to work with the President, but I will not be a rubber stamp for any president. Daniel Inouye
prepare
This withdrawal should prepare for the establishment of an independent Palestinian state, Ahmed Qurei
prepared quick ready
We didn't think he was that fast. He's pretty quick but we were ready for it. We were prepared for everything they did. DeMeco Ryans
program explaining ifs
If a listener nods his head when you're explaining your program, wake him up. Alan Perlis
program
The Libyan program recently discovered was far more extensive than was assessed prior to that. David Kay
program programming ifs
If we can't program it, we can't understand it. David Deutsch
program understood ifs
If you can’t program it, you haven’t understood it. David Deutsch
program six students
We started participating in the program in 2004. We started with six students at the Rockledge hospital, and now we have 12 there and two in Melbourne. Sandy Williams
program save sooner
Sooner or later the space program will need to save us by detecting and deflecting an incoming asteroid. Nathan Myhrvold
program advantage admission
Early admission programs tend to advantage the advantaged. Derek Bok
program social social-programs
I don't like a lot of social programs either because it makes you non-productive. Charles Evers
program support turn
We've been able to turn the program around and we're an (Jayhawk East) power. That's just because of the support that we've received. Josh Matthews
skills honey taste
Most plagiarists, like the drone, have neither taste to select, industry to acquire, nor skill to improve, but impudently pilfer the honey ready prepared, from the hive. Charles Caleb Colton
skills generations novelists
We're currently living with a generation of established novelists who are embarrassingly out of date with respect to social networking, internet skills, and so on. Charles Stross
skills perception taoism
But the transformation of consciousness undertaken in Taoism and Zen is more like the correction of faulty perception or the curing of a disease. It is not an acquisitive process of learning more and more facts or greater and greater skills, but rather an unlearning of wrong habits and opinions. As Lao-tzu said, "The scholar gains every day, but the Taoist loses every day. Alan Watts
skills age lucky
And the maestro surely wielded the chairman's baton with extraordinary skill. His stellar record suggests that the only right answer to the age-old question of whether it is better to be lucky or good may be: both. Alan Blinder
skills cards world
I don't know if this is an illusion but I would love to be able to take my card-throwing skills and be able to puncture a watermelon. Now I know I can take this question and say, "I would want to solve the economic problems in the world" - but I want to stick that card in that watermelon. Dave Franco
skills judging-yourself luck
Don't confuse luck with skill when judging others, and especially when judging yourself. Carl Icahn
skills class looks
You've got to look and pick your shots - and that's where your class and skill comes out. Billy Joe Saunders
skills mind soil
In the productions of the mind, as in those of the soil, the gifts of nature are excelled by industry and skill . . . Edward Gibbon
skills energy kind
Picasso is still influencing me. Of course, I haven't got that kind of energy, or skill. David Hockney
supporting
I know I could make a difference by supporting the right causes. Nell Newman
supporting wants win
He wants to win and we're just supporting him. Teresa Johnson
supporting
The only thing is we didn't have the supporting cast. Marcel Dionne
supporting tired winds
I think the winds are changing. We're all tired of supporting the scandals. Debbie Smith
supporting supports
I'm still undecided about who I'm supporting for governor, but I'm a person who supports the anti-Nussle campaign. Robin Butler
supporting
They say they're supporting the troops, but they're not. Steve Gillis
supporting whether
You need supporting actors to help to tell the story. For me, I'm lucky to be a part of the films. Being an actor, I'll take any role, whether it's supporting or leading. Robert Maillet
supporting
Supporting causes with whatever we do can be effective. Waris Ahluwalia
supporting tradition
The E.U. has a long tradition of supporting the Palestinians. Robert Lowe
teaches
It's not the winning that teaches you how to be resilient. It's the setback. It's the loss. Beth Brooke
teaches
Everything we say and everything we do teaches something to our children. E.R. Rock
teaches
Each one wanted to be the one who teaches her about life. Anne Francis
workers
I am a compulsive worker. But I'm also a compulsive relaxer. A. Scott Berg
workers hardest felt
I never felt entitled to anything. I'm the hardest worker I know. Daryl Hall
workers
Every workers should be honored, every worker should be respected. Paul Lopez
workers
Workers making more than $100,000 in yearly salary, Cynthia Morgan
workers
They will do anything for the worker, except become one. Gregory Benford
workers
In effect, it shuts them down. They're not permitting workers to be employed. Dean Fryer
workers disgruntled
Workers insist that they are not disgruntled. They are very gruntled. Kevin Nealon
workers barack american-workers
Barack Obama is betting on the American worker. Ted Strickland