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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
business soul prosperity
Industry is the soul of business and the keystone of prosperity. Charles Dickens
business fighting men
An Irish man fights before he reasons, a Scotchman reasons before he fights, an Englishman is not particular as to the order of precedence, but will do either to accommodate his customers. Charles Caleb Colton
business men morality
Most men are individuals no longer so far as their business, its activities, or its moralities are concerned. They are not units but fractions. Charles Dickens
business clever men
The first rule of business is: Do other men for they would do you Charles Dickens
business law brain
Contract law is essentially a defensive scorched-earth battleground where the constant question is, "if my business partner was possessed by a brain-eating monster from beyond spacetime tomorrow, what is the worst thing they could do to me?" Charles Stross
business past derivatives
It seems superfluous to constrain trading in some of the newer derivatives and other innovative financial contracts of the past decade. The worst have failed; investors no longer fund them and are not likely to in the future. Alan Greenspan
business colleagues depends
...our market system depends critically on trust-trust in the word of our colleagues and trust in the word of those with whom we do business. Alan Greenspan
business years risk
What we have found over the years in the marketplace is that derivatives have been an extraordinarily useful vehicle to transfer risk from those who shouldn't be taking it to those who are willing to and are capable of doing so. Alan Greenspan
business greatness views
I have found no greater satisfaction than achieving success through honest dealing and strict adherence to the view that, for you to gain, those you deal with should gain as well. Alan Greenspan
commitment ifs
He did each single thing as if he did nothing else. Charles Dickens
commitment reflection giving
Each of us will eventually give away all our earthly possessions. How we choose to do so, however, is a reflection of our commitment to the kingdom of God. Charles Stanley
commitment giving acres
It is true that Mr. Lincoln signed the Emancipation Proclamation, after which there was a commitment to give 40 acres and a mule. That's where the argument, to this day, of reparations starts. We never got the 40 acres. We went all the way to Herbert Hoover, and we never got the 40 acres. We didn't get the mule. So we decided we'd ride this donkey as far as it would take us. Al Sharpton
commitment fargo local looking request san
We want them to have that local commitment to the community, and that's a big part of our request for proposals. We're not looking for Wells Fargo out of San Francisco. Tim Sanders
commitment pinch playing term
We want to try and pinch some of their ball. Nathan has a long term commitment to playing for Scotland. Frank Hadden
commitment thinking gas
I'm totally in favour of meeting our Paris commitments to reduce greenhouse gas emissions. But I don't think we should do that by making ourselves uncompetitive. Chris Alexander
commitment artist political
There is something about important stories that is not just the message, but also the way that message is conveyed, the arrangement of the words, the felicity of the language. So it's really a balance between your commitment, whether it's political or economic or whatever, and your craft as an artist. Chinua Achebe
commitment drug hiv
Treating HIV/AIDS is a lifelong commitment that demands strict adherence to drug protocols, consistent care, and a trusting relationship with health care providers. David Mixner
commitment political environmental
What's now urgently needed [to stop environmental disaster] is the international political commitment to take action to avoid dangerous climate change. David Miliband
committed
But resist we much. We must, and we will much- about that- be committed. Al Sharpton
committed county ends near offices opposite protecting seems whereas
The performances of the different offices are on opposite ends of the spectrum. In Fresno County we have what seems to be a near abdication of their responsibilities, whereas in Alameda County we see an office committed to protecting all residents in the county. Chris Daly
committed future meet money needs praying projects street
We are praying we don't have an earthquake, ... This is money we've committed to sewer, street and other projects to meet the future needs of our city. G. H. Hardy
committed good individual ourselves team
We've all committed ourselves to having a good team, and we have a lot of individual talent. I think one-on-one, individually, we're better than any team in the country. Dane Moody
committed gate good guys help last penalties playing slow
We started slow out of the gate last week, and had some turnovers early. We also committed a lot of penalties and we know we can't do that this week. I've told our guys that Bowman is good enough as it is, and we don't need to help them by playing sloppy. Joey Lott
committed disagree great prices remain selection sharing strongly toys web
We strongly disagree with the judge's ruling. We remain committed to sharing a great selection of toys at great prices for our Web site. Patricia Smith
committed disagree great prices providing regardless ruling selection strongly toys
We strongly disagree with the judge's ruling in this case. Regardless of today's decision, Amazon.com is still committed to providing a great selection of toys at great prices for our customers. Patti Smith
committed project remain specific
We still remain committed to the development of an import terminal. It's not that the project is not occurring, it's just that these specific negotiations have ended. Doug Oliver
committed remain
We still remain committed to the development of an import terminal. Doug Oliver
experience
It is far better to borrow experience than to buy it. Charles Caleb Colton
experience taste helpful
One has to taste an experience for oneself and find out if the thing is genuine or helpful. Then, before discarding something, one has to go further, so that one gets firsthand experience. Chogyam Trungpa
experience incredible powerful pushed scores stories wonderful work
It was a wonderful experience to work with Sylvia. She pushed me to be more powerful with my acting, and she told me scores of the most incredible stories I've ever heard. She is amazing. Lukas Haas
experience hope negative remind talk whenever
I hope that whenever my daughter has a negative experience, I'm there to talk about it and remind her how we feel when it's done to her so that she doesn't do it to others. Lorraine Toussaint
experience lived richest
The person who has lived the most is not the one who has lived the longest, but the one with the richest experiences Jean-Jacques Rousseau
experience
We've all had experience to this point, which has been good. Mike Cisco
experience loved side totally west
West Side Story. It's a totally new experience for me. I've always loved theater. Diana DeGarmo
experience fools start wise
We start as fools and become wise through experience African Proverb
experience mental playing talent top tremendous
When you've got talent from top to bottom, everybody's playing to count. It's a tremendous experience to play without that mental cushion. Dan Brooks
relationship believe two
I don't want to be your other half. I believe that one and one make two. Alanis Morissette
relationship honesty wife
Marriage requires searing honesty at all costs. I learned that from my third wife. Alan Arkin
relationship leadership responsibility
We treat employees as a member of the family. If management take the risk of hiring them, we have to take the responsibility for them. Akio Morita
relationship sex passion
Hugh and I have been together for so long that in order to arouse extraordinary passion, we need to engage in physical combat. Once, he hit me on the back of the head with a broken wineglass, and I fell to the floor pretending to be unconscious. That was romantic, or would have been had he rushed to my side rather than stepping over my body to fetch the dustpan. David Sedaris
relationship girl realizing
I'd had a relationship with a French girl, a Japanese girl, an American girl, a Filippina and she was there all the time - a Lancashire girl. I thought: 'It's a Lancashire girl I was looking for. Why didn't I realize it? David Thewlis
relationship sex opposites
To succeed with the opposite sex, tell her you're impotent. She can't wait to disprove it. Cary Grant
relationship
Where to start? ... This has been a long, love-hate relationship between myself and the French. Lance Armstrong
relationship voice scare
I care," he said in a trembling voice. "I care so much that I do not know how to tell you without it seeming inconsequential compared to how I feel. Even if I am distant at times and seem as if I do not want to be with you, it is only because this scares me, too. Aimee Carter
relationship needs given
You've given me the best of you, but now I need the rest of you. Billy Joel
strong jobs men
No two things differ more than hurry and dispatch. Hurry is the mark of a weak mind, dispatch of a strong one. A weak man in office, like a squirrel in a cage, is laboring eternally, but to no purpose, and is in constant motion without getting on a job; like a turnstile, he is in everybody's way, but stops nobody; he talks a great deal, but says very little; looks into everything but sees nothing; and has a hundred irons in the fire, but very few of them are hot, and with those few that are, he only burns his fingers. Charles Caleb Colton
strong mind haste
Hurry is the mark of a weak mind, dispatch of a strong one. Charles Caleb Colton
strong party reason
He that aspires to be the head of a party will find it more difficult to please his friends than to perplex his foes. He must often act from false reasons which are weak, because he dares not avow the true reasons which are strong. Charles Caleb Colton
strong hands monsters
The mob is a monster, with the hands of Briareus, but the head of Polyphemus,--strong to execute, but blind to perceive. Charles Caleb Colton
strong advice desire
When we feel a strong desire to thrust our advice upon others, it is usually because we suspect their weakness; but we ought rather to suspect our own. Charles Caleb Colton
strong passion may
Strong as our passions are, they may be starved into submission, and conquered without being killed. Charles Caleb Colton
strong men thinking
Men of strong minds and who think for themselves, should not be discouraged on finding occasionally that some of their best ideas have been anticipated by former writers; they will neither anathematize others nor despair themselves. They will rather go on discovering things before discovered, until they are rewarded with a land hitherto unknown, an empire indisputably their own, both right of conquest and of discovery. Charles Caleb Colton
strong circles errors
Unity of opinion is indeed a glorious and desirable thing, and its circle cannot be too strong and extended, if the centre be truth; but if the centre be error, the greater the circumference, the greater the evil. Charles Caleb Colton
strong two mind
No two things differ more than hurry and despatch. Hurry is the mark of a weak mind; despatch of a strong one. Charles Caleb Colton
successful mislead-us watches
Falsehood is never so successful as when she baits her hook with truth, and no opinions so fatally mislead us as those that are not wholly wrong, as no watches so effectively deceive the wearer as those that are sometimes right. Charles Caleb Colton
success pride winning
To know a man, observe how he wins his object, rather than how he loses it; for when we fail, our pride supports us - when we succeed, it betrays us. Charles Caleb Colton
success achievement conceit
Success seems to be that which forms the distinction between confidence and conceit. Charles Caleb Colton
success hate men
For one man who sincerely pities our misfortunes, there are a thousand who sincerely hate our success. Charles Caleb Colton
success kissing hands
To judge by the event is an error all commit: for in every instance courage, if crowned with success, is heroism; if clouded by defeat, temerity. When Nelson fought his battle in the Sound, it was the result alone that decided whether he was to kiss a hand at court or a rod at a court-martial. Charles Caleb Colton
success congratulations adversity
Constant success shows us but one side of the world; adversity brings out the reverse of the picture. Charles Caleb Colton
success achievement silence
Constant success shows us but one side of the world. For as it surrounds us with friends who will tell us only our merits, so it silences those enemies from whom alone we can learn our defects. Charles Caleb Colton
successful causes flourishing
The increasing importance of Sydney must in some measure be attributed to the flourishing condition of the colony itself, to the industry of its farmers, to the successful enterprise of its merchants, and to particular local causes. Charles Sturt
success eggs laziness
The goose that lays the golden eggs likes to lay where there are eggs already. Charles Spurgeon
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
tired conceit found
None are so seldom found alone, and are so soon tired of their own company, as those coxcombs who are on the best terms with themselves. Charles Caleb Colton
tired writing skills
For someone who is starting out on developing their critical skills, just being aware of its existence is great: it can make the difference between trying to write a story around a cliche or an original idea, and better still, studying it can eventually clue you in on how to breathe new life into tired tropes. Charles Stross
tired here-i-am people
Janey accuses me of chasing jailbait. She bursts into angry tears, asking if it's because she's getting older. It's true. She's aging more noticeably every day—while I am standing still. I prefer the stillness here. I am tired of Earth. These people. I am tired of being caught in the tangle of their lives. Alan Moore
tired people action
The American people are tired. They're tired of the bickering in Washington, D.C., and the lack of action. Chris Christie
tired talking buffett
I'm so tired of talking about Warren Buffett. Chris Christie
tired im-tired
I'm tired of dealing with the crazies. Chris Christie
tired people long
There's always something ridiculous happening on the set, especially when people get tired because of the long days. Chiwetel Ejiofor
tired heart home
Good words will not give my people good health and stop them from dying. Good words will not get my people a home where they can live in peace and take care of themselves. I am tired of talk that comes to nothing. It makes my heart sick when I remember all the good words and broken promises. Chief Joseph
tired broken-promises american-indian
I am tired of talk that comes to nothing. Chief Joseph