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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
bulk hard judge
We started getting the bulk of it after dark, so it is hard to judge (the damage). Allen Smith
bulk climate community directly global greenhouse large linked scientific seeing signature
What we're seeing right now in global climate temperature is a signature of climate change. The large bulk of the scientific community say what we are seeing now is linked directly to greenhouse gases. Greg Holland
bulk conscious directing maybe odd taken
I'm very conscious of the fact the directing career has taken some odd turns. Maybe there's enough bulk where I'm now pigeonholed in the 'eclectic box.' Kenneth Branagh
bulk decided helped involved mom sure
She and her mom were so involved with kids, she decided the bulk of it would go to the children's hospital. She wanted to make sure it helped children. Gerald Batto
bulk hang hats reality
The reality is the bulk of this construction is going to be occurring in mid-2007 and beyond, ... At the end of the day, this isn't something (investors) should hang their hats on. Don Roberts
bulk collection constitution defend exactly gather judicial perhaps rely warrants
How will we defend ourselves if the Patriot Act expires? Well, perhaps we could just rely on the Constitution and demonstrate exactly how traditional judicial warrants can gather all the info we need - and how bulk collection really hasn't worked. Rand Paul
bulk either hands money people proven retired shop spending time women
In America, it has been proven that the bulk of spending money is in the hands of women between 60 and 80, so it's so stupid. The people who do have the time and money to shop are either retired or empty-nesters. Iris Apfel
bulk gate released spot three
We released three bulk lots. There have been spot shortages because Chiron got out of the gate late. Julie Zawisza
bulk gate released spot three
We released three bulk lots, ... There have been spot shortages because Chiron got out of the gate late. Julie Zawisza
cancer sugar causes
Syntactic sugar causes cancer of the semicolon. Alan Perlis
cancer scary
It's a scary word, 'cancer. Alan Jackson
cancer illness bores
Cancer, like any other illness, is a bore. Alan Bennett
cancer light focus
A laser is a weak source of energy. A laser takes [only] a few watts of energy and focuses them in a coherent stream of light. But with a laser, you can drill a hole in a diamond or wipe out cancer. Al Ries
cancer return beats
I'm starting to understand that fear is like cancer - you can beat it back, but if it returns, it can be worse than ever. Darren Shan
cancer florida numbers
Florida's number three industry, behind tourism and skin cancer, is voter fraud. Dave Barry
cancer moving heart
The medical literature tells us that the most effective ways to reduce the risk of heart disease, cancer, stroke, diabetes, Alzheimer's, and many more problems are through healthy diet and exercise. Our bodies have evolved to move, yet we now use the energy in oil instead of muscles to do our work. David Suzuki
cancer population affected
I was told 50 percent of the population gets cancer. Everybody is going to be affected. Catherine Hardwicke
cancer knees firsts
With Alexander's cancer, I was definitely brought to my knees for the first time because of the fear factor. Cathy Freeman
data people needs
People will come to your site because you have good compelling content. You need to hit it from all angles: blog posts, articles, graphs, data, infographics, interactive content - even short pictures when you Tweet. Chris Bennett
data earlier economic enron investors life lock looking looks move next picture positive profits selling serious signs starting step tone toward year
The positive tone has more to do with the economic data that showed some signs of life in the economy. We've got through the Enron debacle and some selling that represented investors looking to lock in profits earlier on. Now we're starting to get a serious picture of what next year looks like, and it's probably the first serious step toward an upward move in the market. Joseph Battipaglia
data fortune fun hacking seeing shift theft
We are seeing a shift from the destruction of data to the theft of data. They are going from hacking for fun to hacking for fortune. Dean Turner
data economy saying starting tends
There are data saying that the economy is starting to recover, and there are data saying that it tends to be weak, William McDonough
data interface link management platform services single voice
We're integrating voice and data services on one platform -- with a single management interface and a single link to the Internet, Lewis Platt
data facts judgment
Making good judgments when one has complete data, facts, and knowledge is not leadership - it's bookkeeping Dee Hock
data used connected
Everybody is connected to everybody else, all data that can be shared will be shared: get used to it. Eben Moglen
data inquiring scientist
A scientist naturally and inevitably ... mulls over the data and guesses at a solution. He proceeds to testing of the guess by new data-predicting the consequences of the guess and then dispassionately inquiring whether or not the predictions are verified. Edwin Powell Hubble
data finals body
If the assumptions used in calculating energy are changed, then this seriously affects the final result, even though the same body of data might be used. Charles Francis Richter
firm overhead pay placement tough
We are pretty tough on fees. We are not going to pay a firm more because they have some overhead with a placement agent. Brad Pacheco
firm left newspaper shame sound stand standing view
We still stand firm in our view that there should be two newspapers. It would be a shame if there was arbitration, and only one newspaper left standing after all of this sound and fury. Anne Bremner
firm stand-firm
Stand firm, don't flutter! Benjamin Franklin
firm four looks next six sooner weeks
We're getting down to the wire. Looks to be in the next four to six weeks or sooner there will be some firm announcements of where we'll land. Brian France
firm
For who so firm that cannot be seduced? William Shakespeare
firm
Once when I was a fugitive, I was working for a law firm in Denver. Kevin Mitnick
firm love women
I'm pretty firm in my sexuality and my love for women. Kenny Chesney
firm learned past practices regret stronger subject tax
We regret the past tax practices that were the subject of the investigation. KPMG is a better and stronger firm today, having learned much from this experience. Timothy Flynn
firm intervene political position remain remained shall stand united
We have remained firm in our position that we shall remain united in this stand not to intervene in any of the political undertakings, Generoso Senga
remove
When you remove layers, simplicity and speed happen. Ginni Rometty
remove request title
We did get a request from the publisher to remove the title and we've done so. Patti Smith
remove
If they're in a destructive mood, we'll remove the mat, too. Kat Clark
remove restraint severe
Remove severe restraint and what will become of virtue? Lucius Annaeus Seneca
remove
Remove failure as an option. Joan Lunden
remove scare
The scare is if they remove the steroids, it can return. Terry Greene
remove statistics
Through the survey, we are able to remove the 'water' from the statistics of the manufacturing sector, in particular, from small-sized enterprises. Li Deshui
remove inhibitions
Remove literary, grammatical and syntactical inhibition, Jack Kerouac
remove
Only God who appointed me will remove me. Robert Mugabe
showing toning
Like to me, I did the 'Harajuku' stuff. I did the crazy stuff. And now I kind of want to tone that back, and it's not toning my personality back, it's just showing like I don't only have to do that. Nicki Minaj
showing
We're showing the film to show the underbelly of the porn industry. Eric Woods
showing
We're showing growth. It's pretty slow, but it's more up than down. Elma Damon
showing-up daring
There’s nothing more daring than showing up, putting ourselves out there and letting ourselves be seen. Brene Brown
showing somebody time
Every time I look at Twitter, there's always somebody showing support. French Montana
showing-up way plans
Love has a funny way of showing up when you aren't looking for it and didn't plan on it. Adriana Trigiani
showing somebody telling
For me, the act of telling the story and showing it to somebody is almost gravy. Joss Whedon
showing-up overcoming-fear daring-greatly
Courage starts with showing up and letting ourselves be seen. Brene Brown
showing
Me jumping on a song with Ariana Grande is just showing versatility, you know what I'm saying? ASAP Ferg
successful mislead-us watches
Falsehood is never so successful as when she baits her hook with truth, and no opinions so fatally mislead us as those that are not wholly wrong, as no watches so effectively deceive the wearer as those that are sometimes right. Charles Caleb Colton
successful causes flourishing
The increasing importance of Sydney must in some measure be attributed to the flourishing condition of the colony itself, to the industry of its farmers, to the successful enterprise of its merchants, and to particular local causes. Charles Sturt
successful men errors
Complicity with error will take from the best of men the power to enter any successful protest against it. Charles Spurgeon
successful mud viruses
Why do we argue? Life's so fragile, a successful virus clinging to a speck of mud, suspended in endless nothing. Alan Moore
successful coins tossers
The probability of ten consecutive heads is 0.1 percent; thus, when you have millions of coin tossers, or investors, in the end there will be thousands of very successful practitioners of coin tossing, or stock picking. Alan Greenspan
successful stuff way
Corruption, embezzlement, fraud, these are all characteristics which exist everywhere. It is regrettably the way human nature functions, whether we like it or not. What successful economies do is keep it to a minimum. No one has ever eliminated any of that stuff. Alan Greenspan
successful thinking next
The thing I think about is that once you've done it, you then start to think about what you're going to do next. It's much easier to follow something that's not been as successful as this. Alan Bennett
successful strive do-the-best
Not everything is going to be successful. To strive for that is really naive. You just do the best you can do. Alan Ball
successful animal different
We're highly social animals - I'm told by scientists that what makes us different from other animals is an acute social awareness, which is what has made us so successful. Alan Alda
surgery
Without that, the surgery would not have been possible. Vonetta Flowers
surgery talking
Streamlining is one thing. Amputation surgery is another -- and that's what we're talking about here. John Walke
surgery
The surgery went pretty well. There was nothing unexpected. Terry Greene
surgery took
It took a surgery to get me here. Brian Anderson
surgery
I don't like surgery. I don't like elective surgery, I don't like surgery that you have to have. Sandra Bernhard
women resentment consequence
Women generally consider consequences in love, seldom in resentment. Charles Caleb Colton
women flower sun
Pleasure is to women what the sun is to the flower; if moderately enjoyed, it beautifies, it refreshes, and it improves; if immoderately, it withers, deteriorates and destroys. Charles Caleb Colton
women want ornaments
Modesty is the richest ornament of a woman ... the want of it is her greatest deformity. Charles Caleb Colton
women intellectual female
A high degree of intellectual refinement in the female is the surest pledge society can have for the improvement of the male. Charles Caleb Colton
women doe attention
The plainest man who pays attention to women, will sometimes succeed as well as the handsomest man who does not. Charles Caleb Colton
women modest bashful
Women that are the least bashful are often the most modest. Charles Caleb Colton
women decorum length
Women do not transgress the bounds of decorum so often as men; but when they do, they go greater lengths. Charles Caleb Colton
women said mould
She's the sort of woman now,' said Mould, . . . 'one would almost feel disposed to bury for nothing: and do it neatly, too! Charles Dickens
women want today
You see what happens today. Women act like men and want to be treated like women. Alan Jay Lerner